OECD Guidelines for Testing of Chemicals

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Publisher : Organisation for Economic Co-operation and Development ; [Montréal : Renouf]
ISBN 13 : 9789264122215
Total Pages : pages
Book Rating : 4.1/5 (222 download)

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Book Synopsis OECD Guidelines for Testing of Chemicals by : Organisation for Economic Co-operation and Development

Download or read book OECD Guidelines for Testing of Chemicals written by Organisation for Economic Co-operation and Development and published by Organisation for Economic Co-operation and Development ; [Montréal : Renouf]. This book was released on 1981 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Guidelines for the Testing of Chemicals for Toxicity

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Author :
Publisher :
ISBN 13 :
Total Pages : 74 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis Guidelines for the Testing of Chemicals for Toxicity by : Great Britain. Committee on Toxicity of Chemicals in Food, Consumer Products, and the Environment

Download or read book Guidelines for the Testing of Chemicals for Toxicity written by Great Britain. Committee on Toxicity of Chemicals in Food, Consumer Products, and the Environment and published by . This book was released on 1982 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Toxicity Testing in the 21st Century

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Publisher : National Academies Press
ISBN 13 : 0309109922
Total Pages : 217 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Toxicity Testing in the 21st Century by : National Research Council

Download or read book Toxicity Testing in the 21st Century written by National Research Council and published by National Academies Press. This book was released on 2007-10-05 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in molecular biology and toxicology are paving the way for major improvements in the evaluation of the hazards posed by the large number of chemicals found at low levels in the environment. The National Research Council was asked by the U.S. Environmental Protection Agency to review the state of the science and create a far-reaching vision for the future of toxicity testing. The book finds that developing, improving, and validating new laboratory tools based on recent scientific advances could significantly improve our ability to understand the hazards and risks posed by chemicals. This new knowledge would lead to much more informed environmental regulations and dramatically reduce the need for animal testing because the new tests would be based on human cells and cell components. Substantial scientific efforts and resources will be required to leverage these new technologies to realize the vision, but the result will be a more efficient, informative and less costly system for assessing the hazards posed by industrial chemicals and pesticides.

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 423: Acute Oral toxicity - Acute Toxic Class Method

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Author :
Publisher : OECD Publishing
ISBN 13 : 9264071008
Total Pages : 14 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 423: Acute Oral toxicity - Acute Toxic Class Method by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 423: Acute Oral toxicity - Acute Toxic Class Method written by OECD and published by OECD Publishing. This book was released on 2002-02-08 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a test guideline for testing for Acute Oral Tosxidity using the Acute Toxic Class Method.

Test No. 223: Avian Acute Oral Toxicity Test

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Publisher : OECD Publishing
ISBN 13 : 9264090894
Total Pages : 25 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis Test No. 223: Avian Acute Oral Toxicity Test by : OECD

Download or read book Test No. 223: Avian Acute Oral Toxicity Test written by OECD and published by OECD Publishing. This book was released on 2010-07-23 with total page 25 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes procedures designed to estimate the acute oral toxicity of substances to birds, and it provides three testing options: (1) limit dose test, (2) LD50-slope test, and (3) LD50-only test. The LD50-slope and LD50-only ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 420: Acute Oral Toxicity - Fixed Dose Procedure

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Publisher : OECD Publishing
ISBN 13 : 926407094X
Total Pages : 14 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 420: Acute Oral Toxicity - Fixed Dose Procedure by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 420: Acute Oral Toxicity - Fixed Dose Procedure written by OECD and published by OECD Publishing. This book was released on 2002-02-08 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt: A principle of the method is that in the main study only moderately toxic doses are used, and the administration of doses that are expected to be lethal should be avoided. This Guideline is intended primarily for use with rat. Groups of animals of a ...

Test No. 421: Reproduction/Developmental Toxicity Screening Test

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Publisher : OECD Publishing
ISBN 13 : 9264070966
Total Pages : 10 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis Test No. 421: Reproduction/Developmental Toxicity Screening Test by : OECD

Download or read book Test No. 421: Reproduction/Developmental Toxicity Screening Test written by OECD and published by OECD Publishing. This book was released on 1995-07-27 with total page 10 pages. Available in PDF, EPUB and Kindle. Book excerpt: The test substance is administered in graduated doses to several groups of males and females. Males should be dosed for a minimum of four weeks. Females should be dosed throughout the study, so approximately 54 days. This Test Guideline is designed ...

Toxicity Testing for Assessment of Environmental Agents

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Publisher : National Academies Press
ISBN 13 : 0309164869
Total Pages : 270 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Toxicity Testing for Assessment of Environmental Agents by : National Research Council

Download or read book Toxicity Testing for Assessment of Environmental Agents written by National Research Council and published by National Academies Press. This book was released on 2006-04-07 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicity testing in laboratory animals provides much of the information used by the Environmental Protection Agency (EPA) to assess the hazards and risks associated with exposure to environmental agents that might harm public health or the environment. The data are used to establish maximum acceptable concentrations of environmental agents in drinking water, set permissible limits of exposure of workers, define labeling requirements, establish tolerances for pesticides residues on food, and set other kinds of limits on the basis of risk assessment. Because the number of regulations that require toxicity testing is growing, EPA called for a comprehensive review of established and emerging toxicity-testing methods and strategies. This interim report reviews current toxicity-testing methods and strategies and near-term improvements in toxicity-testing approaches proposed by EPA and others. It identifies several recurring themes and questions in the various reports reviewed. The final report will present a long-range vision and strategic plan to advance the practices of toxicity testing and human health assessment of environmental contaminants.

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies

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Publisher : OECD Publishing
ISBN 13 : 9264071202
Total Pages : 18 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 18 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of these chronic toxicity studies is to characterize the profile of a substance in a mammalian species (primarily rodents) following prolonged and repeated exposure. The Test Guideline focuses on rodents and oral administration. Both ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 414: Prenatal Developmental Toxicity Study

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Publisher : OECD Publishing
ISBN 13 : 9264070826
Total Pages : 14 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 414: Prenatal Developmental Toxicity Study by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 414: Prenatal Developmental Toxicity Study written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline for developmental toxicity testing is designed to provide general information concerning the effects of prenatal exposure on the pregnant test animal and on the developing organism. The test substance is normally administered to ...

Science and Judgment in Risk Assessment

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Publisher : National Academies Press
ISBN 13 : 030904894X
Total Pages : 668 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Science and Judgment in Risk Assessment by : National Research Council

Download or read book Science and Judgment in Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 1994-01-01 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: The public depends on competent risk assessment from the federal government and the scientific community to grapple with the threat of pollution. When risk reports turn out to be overblownâ€"or when risks are overlookedâ€"public skepticism abounds. This comprehensive and readable book explores how the U.S. Environmental Protection Agency (EPA) can improve its risk assessment practices, with a focus on implementation of the 1990 Clean Air Act Amendments. With a wealth of detailed information, pertinent examples, and revealing analysis, the volume explores the "default option" and other basic concepts. It offers two views of EPA operations: The first examines how EPA currently assesses exposure to hazardous air pollutants, evaluates the toxicity of a substance, and characterizes the risk to the public. The second, more holistic, view explores how EPA can improve in several critical areas of risk assessment by focusing on cross-cutting themes and incorporating more scientific judgment. This comprehensive volume will be important to the EPA and other agencies, risk managers, environmental advocates, scientists, faculty, students, and concerned individuals.

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 403: Acute Inhalation Toxicity

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Author :
Publisher : OECD Publishing
ISBN 13 : 9264070605
Total Pages : 20 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 403: Acute Inhalation Toxicity by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 403: Acute Inhalation Toxicity written by OECD and published by OECD Publishing. This book was released on 2009-09-08 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt: This method provides information on health hazard likely to arise from short-term exposure to a test article (gas, vapour or aerosol/particulate test article) by inhalation. The revised Test Guideline describes two studies: a traditional LC50 ...

Toxicity Testing for Assessment of Environmental Agents

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Author :
Publisher : National Academies Press
ISBN 13 : 0309100925
Total Pages : 271 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Toxicity Testing for Assessment of Environmental Agents by : National Research Council

Download or read book Toxicity Testing for Assessment of Environmental Agents written by National Research Council and published by National Academies Press. This book was released on 2006-05-07 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicity testing in laboratory animals provides much of the information used by the Environmental Protection Agency (EPA) to assess the hazards and risks associated with exposure to environmental agents that might harm public health or the environment. The data are used to establish maximum acceptable concentrations of environmental agents in drinking water, set permissible limits of exposure of workers, define labeling requirements, establish tolerances for pesticides residues on food, and set other kinds of limits on the basis of risk assessment. Because the number of regulations that require toxicity testing is growing, EPA called for a comprehensive review of established and emerging toxicity-testing methods and strategies. This interim report reviews current toxicity-testing methods and strategies and near-term improvements in toxicity-testing approaches proposed by EPA and others. It identifies several recurring themes and questions in the various reports reviewed. The final report will present a long-range vision and strategic plan to advance the practices of toxicity testing and human health assessment of environmental contaminants.

OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 210: Fish, Early-life Stage Toxicity Test

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Publisher : OECD Publishing
ISBN 13 : 9264203788
Total Pages : 24 pages
Book Rating : 4.2/5 (642 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 210: Fish, Early-life Stage Toxicity Test by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 210: Fish, Early-life Stage Toxicity Test written by OECD and published by OECD Publishing. This book was released on 2013-07-26 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt: The test method described in this Test Guideline, is intended to define the lethal and sub-lethal effects of chemicals on the early life stages of the species tested. The early-life stages of fish are exposed to five concentrations of the test ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 433: Acute Inhalation Toxicity: Fixed Concentration Procedure

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Author :
Publisher : OECD Publishing
ISBN 13 : 9264284168
Total Pages : 20 pages
Book Rating : 4.2/5 (642 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 433: Acute Inhalation Toxicity: Fixed Concentration Procedure by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 433: Acute Inhalation Toxicity: Fixed Concentration Procedure written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt: This method provides information on health hazard likely to arise from short-term exposure to a test chemical by inhalation. It is a principle of the method that only moderately toxic concentrations are used so that ‘evident toxicity’, rather than death/moribundity is used as an endpoint, and ...

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Document on Aquatic Toxicity Testing of Difficult Substances and Mixtures

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Author :
Publisher : OECD Publishing
ISBN 13 : 9264078401
Total Pages : 53 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Document on Aquatic Toxicity Testing of Difficult Substances and Mixtures by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Document on Aquatic Toxicity Testing of Difficult Substances and Mixtures written by OECD and published by OECD Publishing. This book was released on 2002-05-10 with total page 53 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document provides guidance for the testing of substances, and mixtures, classed as “difficult to test” for the purposes of determining their aquatic toxicity.

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 402: Acute Dermal Toxicity

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Author :
Publisher : OECD Publishing
ISBN 13 : 9264070583
Total Pages : 13 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 402: Acute Dermal Toxicity by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 402: Acute Dermal Toxicity written by OECD and published by OECD Publishing. This book was released on 2017-10-09 with total page 13 pages. Available in PDF, EPUB and Kindle. Book excerpt: This method provides information on health hazard likely to arise from a short-term exposure to solid or liquid test substance by the dermal route. This Test Guideline is intended primarily for use with rodents (rat, rabbit or guinea pig may be ...