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Guidelines For The Clinical Evaluation Of Drugs Used In The Treatment Of Osteoporosis
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Author :United States. Food and Drug Administration. Division of Metabolism and Endocrine Drug Products Publisher : ISBN 13 : Total Pages :16 pages Book Rating :4.:/5 (319 download)
Book Synopsis Guidelines for the Clinical Evaluation of Drugs Used in the Treatment of Osteoporosis by : United States. Food and Drug Administration. Division of Metabolism and Endocrine Drug Products
Download or read book Guidelines for the Clinical Evaluation of Drugs Used in the Treatment of Osteoporosis written by United States. Food and Drug Administration. Division of Metabolism and Endocrine Drug Products and published by . This book was released on 1979 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Guidelines for the Clinical Evaluation of Drugs Used in the Treatment of Osteoporosis by :
Download or read book Guidelines for the Clinical Evaluation of Drugs Used in the Treatment of Osteoporosis written by and published by . This book was released on 1979 with total page 5 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Guidelines for Clinical Evaluation of Agents Used in the Treatment Or Prevention of Osteoporosis by : United States. Food and Drug Administration
Download or read book Guidelines for Clinical Evaluation of Agents Used in the Treatment Or Prevention of Osteoporosis written by United States. Food and Drug Administration and published by . This book was released on 1985 with total page 9 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :United States. Food and Drug Administration. Division of Metabolism and Endocrine Drug Products Publisher : ISBN 13 : Total Pages :20 pages Book Rating :4.:/5 (352 download)
Book Synopsis Guidelines for Preclinical and Clinical Evaluation of Agents Used in the Prevention Or Treatment of Postmenopausal Osteoporosis by : United States. Food and Drug Administration. Division of Metabolism and Endocrine Drug Products
Download or read book Guidelines for Preclinical and Clinical Evaluation of Agents Used in the Prevention Or Treatment of Postmenopausal Osteoporosis written by United States. Food and Drug Administration. Division of Metabolism and Endocrine Drug Products and published by . This book was released on 1994 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Guidelines for Preclinical Evaluation and Clinical Trials in Osteoporosis by : World Health Organization
Download or read book Guidelines for Preclinical Evaluation and Clinical Trials in Osteoporosis written by World Health Organization and published by . This book was released on 1998-01-01 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides comprehensive guidelines for the design, implementation, and interpretation of preclinical studies and clinical trials of agents undergoing investigation for the management of osteoporosis. Noting the magnitude of the public health problem caused by osteoporosis and related fractures, the book responds to the urgent need for a cohesive and rational approach to the search for new therapeutic or preventive agents. Recommended principles and methods reflect the consensus reached by a large number of international experts, representatives of the pharmaceutical industry, and drug regulatory authorities. The book opens with a brief discussion of the current and future public health problem caused by osteoporotic fractures, followed by conceptual and operational definitions of osteoporosis and a recommended classification of four intervention categories that facilitate the definition of treatment objectives and the design of targetted studies. Against this background, the next chapter offers a detailed guide to the aims, design, conduct and interpretation of preclinical studies. Specific recommendations are given for the selection of in vitro and animal models, the design of the study, including dose ranges and duration of treatment, and the most appropriate end-points for assessing efficacy. The most extensive chapter provides a comprehensive description of basic principles and methods to follow during clinical trials. Information ranges from a discussion of problems with the use of bone mineral density to predict fracture risk, through advice on the choice of tests and techniques for measuring the effects of interventions, to a discussion of general principles of trial design, including selection of study population, treatment regimen, duration of studies, sample size, and frequency of measurement. Drawing on these detailed principles and methods, subsequent chapters offer concise guidance specific to phase I and phase II studies, phase III studies in severe osteoporosis, phase III studies in osteoporosis without fragility fractures, and phase III studies in osteopenia. The book concludes with chapters outlining principles and methods for phase III clinical trials in subjects with normal bone mass, and for phase IV studies.
Book Synopsis Osteoporosis in Men by : Eric S. Orwoll
Download or read book Osteoporosis in Men written by Eric S. Orwoll and published by Academic Press. This book was released on 2009-11-30 with total page 764 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the first edition, the U.S. Surgeon General released the first-ever report on bone health and osteoporosis in October 2004. This report focuses even more attention on the devastating impact osteoporosis has on millions of lives. According to the National Osteoporosis Foundation, 2 million American men have osteoporosis, and another 12 million are at risk for this disease. Yet despite the large number of men affected, the lack of awareness by doctors and their patients puts men at a higher risk that the condition may go undiagnosed and untreated. It is estimated that one-fifth to one-third of all hip fractures occur in men. This second edition brings on board John Bilezikian and Dirk Vanderschueren as editors with Eric Orwoll. The table of contents is more than doubling with 58 planned chapters. The format is larger – 8.5 x 11. This edition of Osteoporosis in Men brings together even more eminent investigators and clinicians to interpret developments in this growing field, and describe state-of-the-art research as well as practical approaches to diagnosis, prevention and therapy. Brings together more eminent investigators and clinicians to interpret developments in this growing field Describes state-of-the-art research as well as practical approaches to diagnosis, prevention and therapy There is no book on the market that covers osteoporosis in men as comprehensively as this book
Author :United States. Food and Drug Administration. Division of Oncology and Radiopharmaceutical Drug Products Publisher : ISBN 13 : Total Pages :24 pages Book Rating :4.:/5 (318 download)
Book Synopsis Guidelines for the Clinical Evaluation of Radiopharmaceutical Drugs by : United States. Food and Drug Administration. Division of Oncology and Radiopharmaceutical Drug Products
Download or read book Guidelines for the Clinical Evaluation of Radiopharmaceutical Drugs written by United States. Food and Drug Administration. Division of Oncology and Radiopharmaceutical Drug Products and published by . This book was released on 1981 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Guidelines for the Clinical Evaluation of Radiopharmaceutical Drugs by : United States. Food and Drug Administration. Bureau of Drugs
Download or read book Guidelines for the Clinical Evaluation of Radiopharmaceutical Drugs written by United States. Food and Drug Administration. Bureau of Drugs and published by . This book was released on 1981 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Guidelines for the Clinical Evaluation of Antineoplastic Drugs by :
Download or read book Guidelines for the Clinical Evaluation of Antineoplastic Drugs written by and published by . This book was released on 1981 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Guidelines for the Clinical Evaluation of Drugs to Prevent, Control and by : United States. Food and Drug Administration
Download or read book Guidelines for the Clinical Evaluation of Drugs to Prevent, Control and written by United States. Food and Drug Administration and published by . This book was released on 1978 with total page 4 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :United States. Food and Drug Administration. Division of Neuropharmacological Drug Products Publisher : ISBN 13 : Total Pages :20 pages Book Rating :4.:/5 (318 download)
Book Synopsis Guidelines for the Clinical Evaluation of Antiepileptic Drugs (adults and Children). by : United States. Food and Drug Administration. Division of Neuropharmacological Drug Products
Download or read book Guidelines for the Clinical Evaluation of Antiepileptic Drugs (adults and Children). written by United States. Food and Drug Administration. Division of Neuropharmacological Drug Products and published by . This book was released on 1981 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :United States. Food and Drug Administration. Division of Metabolism and Endocrine Drug Products Publisher : ISBN 13 : Total Pages :20 pages Book Rating :4.:/5 (319 download)
Book Synopsis Guidelines for the Clinical Evaluation of Lipid-altering Agents in Adults and Children by : United States. Food and Drug Administration. Division of Metabolism and Endocrine Drug Products
Download or read book Guidelines for the Clinical Evaluation of Lipid-altering Agents in Adults and Children written by United States. Food and Drug Administration. Division of Metabolism and Endocrine Drug Products and published by . This book was released on 1980 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :Andrea Giustina Publisher :Karger Medical and Scientific Publishers ISBN 13 :3805572964 Total Pages :213 pages Book Rating :4.8/5 (55 download)
Book Synopsis Glucocorticoid-induced Osteoporosis by : Andrea Giustina
Download or read book Glucocorticoid-induced Osteoporosis written by Andrea Giustina and published by Karger Medical and Scientific Publishers. This book was released on 2002 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: Osteoporosis is one of the most clinically relevant disabling chronic disease encountered in clinical practice. A common cause of osteoporosis is glucocorticoid excess, as glucocorticoids may increase bone resorption, inhibit bone formation, have indirect actions on bone by decreasing intestinal calcium absorption and induce hypercalciuria. This book presents a comprehensive overview of the effects of glucocorticoids on bone metabolism and structure and on the diagnosis and treatment of glucocorticoid-induced osteoporosis. It aims at providing updated information on the pathogenesis, diagnosis and treatment of this often dramatic complication of glucocorticoid excess. Being one of the few publications completely devoted to glucocorticoid-induced osteoporosis it will heighten the awareness of specialists who prescribe glucocorticoids of the clinical relevance of this treatment complication. 'Glucocorticoid-Induced Osteoporosis' is addressed to clinical experts as well as to general practitioners who will both benefit from the comprehensive and integrative view of the management of patients exposed to glucocorticoids.
Book Synopsis The Osteoporosis Manual by : Reiner Bartl
Download or read book The Osteoporosis Manual written by Reiner Bartl and published by Springer. This book was released on 2019-02-06 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive manual covers all aspects of the prevention, diagnosis and management of osteoporosis, offering an upbeat and optimistic assessment of what can be achieved. While scientifically based, the book provides easy-to-follow guidelines for lifelong maintenance of skeletal structure and function. It deals with everything from the basic physiology of bone and mineral metabolism to the diagnostic utility of radiologic imaging and specialized tests and current treatment recommendations, including for fracture management. The relationship of osteoporosis to a variety of other disorders is also thoroughly explored and elucidated. Osteoporosis represents a global threat because every human being is vulnerable to it as time passes. The authors point out the enormous scale of the problem in terms of the human suffering, morbidity, and mortality on the one hand and the associated astronomical national and global costs on the other. Osteoporosis is preventable, and every doctor in every medical discipline can contribute to this goal. And though prevention is better than cure, it is never too late for effective therapy, as outlined in this book. Bone is every doctorʼs and every bodyʼs business!
Download or read book Osteoporosis written by and published by . This book was released on 2012 with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are a number of therapies and treatments available for the prevention of fragility fractures in people thought to be at risk, or to prevent further fractures in those who have already had one or more fragility fractures. However, identifying who will benefit from preventative treatment is imprecise. A number of risk assessment tools are available to predict fracture incidence over a period of time, and these may be used to aid decision making. These tools are limited in that they may not include all risk factors, or may lack details of some risk factors. Tools are dependent on the accuracy of the epidemiological data used to derive them and tools validated in other populations may not apply to the UK. Two tools, FRAX and QFracture, are available for use in the UK. It is not clear whether these tools are equally accurate and whether choice of tool should depend on circumstances. This short clinical guideline aims to provide guidance on the selection and use of risk assessment tools in the care of people who may be at risk of fragility fractures in all settings in which NHS care is received.
Book Synopsis Anabolic Treatments for Osteoporosis by : James F. Whitfield
Download or read book Anabolic Treatments for Osteoporosis written by James F. Whitfield and published by CRC Press. This book was released on 2013-11-12 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Osteoporosis, a growing epidemic among women in North America, Europe, and Japan, is a painful, costly disease that has presented a treatment challenge to healthcare professionals. Until recently, therapies have focused on agents that slow bone resorption, and have had only limited success at increasing bone mass.
Book Synopsis Goodman and Gilman's Manual of Pharmacology and Therapeutics by : Louis Sanford Goodman
Download or read book Goodman and Gilman's Manual of Pharmacology and Therapeutics written by Louis Sanford Goodman and published by McGraw Hill Professional. This book was released on 2008 with total page 1232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Put the authority of Goodman & Gilman's in the palm of your hand! 5 STAR DOODY'S REVIEW! "...the most authoritative and trusted source of pharmacological information, has now spawned a portable pocket drug guide....This manual extracts the essential core drug information from the eleventh edition of the parent book, referring the reader to the online version of the parent book for historical aspects, many chemical and clinical details, and additional figures and references. This makes G & G a very useful book. This will be of use to individuals in training or practice in the fields of pharmacy, medicine, nursing, or allied health disciplines where knowledge of drug actions are important....Each chapter provides the core essential information provided in the parent book in a very readable format. Readers can use this easy to handle and read manual for essential information along with the online version of the parent book as a reference for more in-depth specific information on drugs."--Doody's Review Service The Goodman & Gilman Manual of Pharmacology and Therapeutics offers the renowned content of Goodman & Gilman's Pharmacological Basis of Therapeutics, Eleventh Edition, condensed into an ultra-handy, streamlined reference. More than just a pocket drug guide, this indispensable resource offers: A carry-along source of essential fundamental information, with all the authority of Goodman & Gilman's Pharmacological Basis of Therapeutics, Eleventh Edition The benefits of the world's leading pharmacology text in a convenient, portable format Comprehensive, yet streamlined and clinically relevant coverage of the pharmacological basis of therapeutics High-yield overview of pharmacokinetics, pharmacodynamics, and the foundations of pharmacology Expert insights into the properties, mechanisms, and uses of all the major drug classes Considerations of vital patient-specific issues
