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Gonadal Steroid Hormones Advances In Research And Application 2011 Edition
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Book Synopsis Gonadal Steroid Hormones: Advances in Research and Application: 2011 Edition by :
Download or read book Gonadal Steroid Hormones: Advances in Research and Application: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gonadal Steroid Hormones: Advances in Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Gonadal Steroid Hormones. The editors have built Gonadal Steroid Hormones: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Gonadal Steroid Hormones in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Gonadal Steroid Hormones: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Book Synopsis Gonadal Hormones: Advances in Research and Application: 2011 Edition by :
Download or read book Gonadal Hormones: Advances in Research and Application: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gonadal Hormones: Advances in Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Gonadal Hormones. The editors have built Gonadal Hormones: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Gonadal Hormones in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Gonadal Hormones: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Book Synopsis Gonadal Steroid Hormones—Advances in Research and Application: 2012 Edition by :
Download or read book Gonadal Steroid Hormones—Advances in Research and Application: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 30 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gonadal Steroid Hormones—Advances in Research and Application: 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Gonadal Steroid Hormones in a compact format. The editors have built Gonadal Steroid Hormones—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Gonadal Steroid Hormones in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Gonadal Steroid Hormones—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Book Synopsis Pituitary Hormone-Releasing Hormones: Advances in Research and Application: 2011 Edition by :
Download or read book Pituitary Hormone-Releasing Hormones: Advances in Research and Application: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pituitary Hormone-Releasing Hormones: Advances in Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Pituitary Hormone-Releasing Hormones in a concise format. The editors have built Pituitary Hormone-Releasing Hormones: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Pituitary Hormone-Releasing Hormones in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Pituitary Hormone-Releasing Hormones: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Book Synopsis Progesterone Congeners—Advances in Research and Application: 2012 Edition by :
Download or read book Progesterone Congeners—Advances in Research and Application: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progesterone Congeners—Advances in Research and Application: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Progesterone Congeners in a concise format. The editors have built Progesterone Congeners—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Progesterone Congeners in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Progesterone Congeners—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Book Synopsis Hormones, Hormone Substitutes, and Hormone Antagonists: Advances in Research and Application: 2011 Edition by :
Download or read book Hormones, Hormone Substitutes, and Hormone Antagonists: Advances in Research and Application: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hormones, Hormone Substitutes, and Hormone Antagonists: Advances in Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Hormones, Hormone Substitutes, and Hormone Antagonists. The editors have built Hormones, Hormone Substitutes, and Hormone Antagonists: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Hormones, Hormone Substitutes, and Hormone Antagonists in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Hormones, Hormone Substitutes, and Hormone Antagonists: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Book Synopsis Corpus Luteum Hormones—Advances in Research and Application: 2012 Edition by :
Download or read book Corpus Luteum Hormones—Advances in Research and Application: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: Corpus Luteum Hormones—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Corpus Luteum Hormones. The editors have built Corpus Luteum Hormones—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Corpus Luteum Hormones in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Corpus Luteum Hormones—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Book Synopsis Assessing Prenatal and Neonatal Gonadal Steroid Exposure for Studies of Human Development: Methodological and Theoretical Challenges by : Rebecca Christine Knickmeyer
Download or read book Assessing Prenatal and Neonatal Gonadal Steroid Exposure for Studies of Human Development: Methodological and Theoretical Challenges written by Rebecca Christine Knickmeyer and published by Frontiers Media SA. This book was released on 2015-07-28 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is extensive evidence from animal models that gonadal steroids, produced in fetal and neonatal life, act on the developing organism to produce sex differences far beyond the reproductive system. That early gonadal steroid exposure also plays an important role in human development is supported by studies of individuals with disorders of sex determination and differentiation. It is much less clear whether normal variation in gonadal steroid exposure predicts sexually dimorphic health outcomes or within-sex variation. This is largely due to challenges related to the assessment of gonadal steroid exposure in the developing fetus and neonate. Regarding the prenatal period, serial measurements of serum hormone levels in the fetus, for use in studies of later development, are not possible for ethical reasons. Researchers have measured hormones in maternal blood, umbilical cord blood, and amniotic fluid; used putative anthropometric indices such as the relative lengths of the 2nd and 4th digits (2D:4D); evaluated common variants in genes related to hormone production, transport, and metabolism; and examined development in opposite sex twins and the offspring of mothers with hyperandrogeny. Each of these approaches has particular strengths and notable weaknesses. Regarding the neonatal period, serial measurements in serum are often impractical for studies of typical development. Salivary hormone assays, frequently used in studies of older children and adults, have not been extensively investigated in neonates. The most appropriate timing for testing is also open to debate. Early work suggested that testosterone levels in males begin to rise after the first postnatal week, peak around the 3rd to 4th months of life, and then drop back to very low levels by 1 year. However a more recent study of 138 infants did not demonstrate this pattern. Testosterone was highest on the day of birth and gradually dropped over the first 6 months. Even less is known about patterns of early estrogen exposure, though highly sensitive bioassays indicated that sex differences are present in early childhood. In addition, the design and interpretation of studies may be impacted by widespread acceptance of conceptual frameworks that are not well-supported empirically. For example, many researchers presume that the free hormone hypothesis, which states that unbound hormone is more readily diffusible into tissues and thus a better measure of actual exposure, is true. However this hypothesis has been challenged on multiple grounds. A second example: it is generally accepted that masculinization of the human brain is primarily mediated by the androgen receptor (in contrast to rodents where the estrogen receptor plays a major role), in part because chromosomal males with complete androgen insensitivity generally espouse a female gender identity. However this is not always the case, and other sexually dimorphic outcomes have not been carefully assessed in CAIS. The aim of this research topic is to gather together experimental and review papers which address the diverse challenges in assessing prenatal and neonatal gonadal steroid exposure for studies of human development with the expectation that this will allow more critical appraisal of existing studies, identify critical research gaps, and improve the design of future studies.
Book Synopsis The Chemistry Between Us by : Larry Young PhD
Download or read book The Chemistry Between Us written by Larry Young PhD and published by Penguin. This book was released on 2014-01-28 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: How much control do we have over love? Much less than we like to think. All that mystery, all that poetry, all those complex behaviors surrounding human bonding leading to the most life-changing decisions we’ll ever make, are unconsciously driven by a few molecules in our brains. How does love begin? How can two strangers come to the conclusion that it would not only be pleasant to share their lives, but that they must share them? How can a man say he loves his wife, yet still cheat on her? Why do others stay in relationships even after the romance fades? How is it possible to fall in love with the “wrong” person? How do people come to have a “type”? Physical attraction, jealousy, infidelity, mother-infant bonding—all the behaviors that so often leave us befuddled—are now being teased out of the fog of mystery thanks to today’s social neuroscience. Larry Young, one of the world’s leading experts in the field, and journalist Brian Alexander explain how those findings apply to you. Drawing on real human stories and research from labs around the world, The Chemistry Between Us is a bold attempt to create a “grand unified theory” of love. Some of the mind-blowing insights include: Love can get such a grip on us because it is, literally, an addiction. To a woman falling in love, a man is like her baby. Why it’s false to say society makes gender, and how it’s possible to have the body of one gender and the brain of another. Why some people are more likely to cheat than others. Why we sometimes truly can’t resist temptation. Young and Alexander place their revelations into historical, political, and social contexts. In the process, they touch on everything from gay marriage to why single-mother households might not be good for society. The Chemistry Between Us offers powerful insights into love, sex, gender, sexual orientation, and family life that will prove to be enlightening, controversial, and thought provoking.
Book Synopsis Recent Progress and Perspectives in Neurosteroid Research by : Hubert Vaudry
Download or read book Recent Progress and Perspectives in Neurosteroid Research written by Hubert Vaudry and published by Frontiers Media SA. This book was released on 2022-08-16 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Principles of Endocrinology and Hormone Action by : Antonino Belfiore
Download or read book Principles of Endocrinology and Hormone Action written by Antonino Belfiore and published by Springer. This book was released on 2018-02-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides comprehensive coverage of the current knowledge of the physiology of the endocrine system and hormone synthesis and release, transport, and action at the molecular and cellular levels. It presents essential as well as in-depth information of value to both medical students and specialists in Endocrinology, Gynecology, Pediatrics, and Internal Medicine. Although it is well established that the endocrine system regulates essential functions involved in growth, reproduction, and homeostasis, it is increasingly being recognized that this complex regulatory system comprises not only hormones secreted by the classic endocrine glands but also hormones and regulatory factors produced by many organs, and involves extensive crosstalk with the neural and immune system. At the same time, our knowledge of the molecular basis of hormone action has greatly improved. Understanding this complexity of endocrine physiology is crucial to prevent endocrine disorders, to improve the sensitivity of our diagnostic tools, and to provide the rationale for pharmacological, immunological, or genetic interventions. It is such understanding that this book is designed to foster.
Book Synopsis An Introduction to Neuroendocrinology by : Richard E. Brown
Download or read book An Introduction to Neuroendocrinology written by Richard E. Brown and published by Cambridge University Press. This book was released on 1994-01-27 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed as an introductory text in neuroendocrinology; the study of the interaction between the brain and endocrine system and the influence of this on behaviour. The endocrine glands, pituitary gland and hypothalamus and their interactions and hormones are discussed. The action of steroid and thyroid hormone receptors and the regulation of target cell response to hormones is examined. The function of neuropeptides is discussed with respect to the neuroendocrine system and behaviour. The neuroimmune system and lymphokines are described and the interaction between the neuroendocrine and neuroimmune systems discussed. Finally, methods for studying hormonal influences on behaviour are outlined. Each chapter has review and essay questions designed for advanced students and honours or graduate students with a background in neuroscience, respectively.
Book Synopsis Testosterone, An Issue of Urologic Clinics, E-Book by : Kevin R. Loughlin
Download or read book Testosterone, An Issue of Urologic Clinics, E-Book written by Kevin R. Loughlin and published by Elsevier Health Sciences. This book was released on 2022-10-29 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Urologic Clinics of North America, guest editor Dr. Kevin R. Loughlin brings his considerable expertise to the topic of Testosterone. With about 2 out of 10 men older than 60 years having low testosterone (American Urological Association), coupled with an aging population, this issue is an important resource for all urologists for effectively treating men and improving outcomes. It provides a current update on testosterone in men from top experts in the field, covering prostate cancer treatment, the use of anabolic steroids, hypogonadism, testosterone replacement, and more. - Contains 15 practice-oriented topics including current management and controversies surrounding andropause; testosterone and male sexual function; the interplay of testosterone and dihydrotestosterone in prostate cancer; and more. - Provides in-depth clinical reviews on testosterone, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Book Synopsis Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays by : Franz J. Hock
Download or read book Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays written by Franz J. Hock and published by Springer Nature. This book was released on 2025-02 with total page 2751 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many aspects of drug safety have become an outstanding and even persistent issue and may occur during the process of both drug discovery and development. Until 15 years ago, drug discovery and evaluation was primarily a sequential process starting with the selection of the most pharmacologically active compound from a series of newly synthesized small molecule chemical series by means of distinctive pharmacological assays. Safety aspects were addressed by evaluation of the selected compound at high doses in a series of specific studies directed at indications other than the intended indication of the new compound. These tests are then followed by pharmacokinetic studies, which are primarily conducted to confirm whether the selected compound possesses a suitable half-life for sufficient exposure and efficacy and, whether it has the desired properties specificity to the intended route of administration. Safety aspects relied predominantly on the conduct of single and repeat toxicologydose studies, which inform changes in organ structure rather than organ function. Both toxicological and pharmacokinetic studies are adapted to the progress of studies in clinical pharmacology and clinical trials. The new edition of this well and broadly accepted reference work contains several innovative and distinguished chapters. This "sequential" strategy has been abandoned with this new version of the book for several reasons: - Of the possible multitude of negative effects that novel drugs may impart on organ function, e.g. ventricular tachy-arrhythmia, many are detected too late in non-clinical studies to inform clinicians. On the other hand, negative findings in chronic toxicity studies in animals may turn out to be irrelevant for human beings. - New scientific approaches, e.g. high-throughput screening, human pluripotent stem cells, transgenic animals, knock-out animals, in silico models, pharmaco-genomics and pharmaco-proteomics, as well as Artificial Intelligence (AI) methods offered new possibilities. - There are several examples, that show that the "druggability" of compounds was considerably underestimated when the probability of success of a new project was assessed. The success rate in the pharmaceutical industry and the introduction of new chemical entities to the market per year dropped dramatically, whereas the development time for a new compound increased, sometimes exceeding the patent protection. Research and development scientists, involving the following changes, therefore adopted a change of strategy: - Parallel instead of sequential involvement of the various disciplines (multidimensional compound optimization). - The term "Safety Pharmacology" was coined. The International Conference on Harmonization (ICH) founded a Safety Pharmacology Working Group and the Safety Pharmacology Society (SPS) was launched. The discipline provided for evaluation, development and validation of a multitude of safety tests outlined in the 'Core Battery of Studies'. - Characterizing the exposure profile of a drug by conducting pharmacokinetic studies that evaluates the absorption, distribution, metabolism and excretion should to be investigated at an early stage of development as results contribute to the selection of a compound for further development. Advancements in Toxicology were achieved by the introduction of new methods, e.g., in silico methods, genetic toxicology, computational toxicology and AI. The book is a landmark in the continuously changing world of drug research and developments. As such, it is essential reading for many groups: not only for all students of pharmacology and toxicology but also for industry scientists and physicians, especially those involved in clinical trials of drugs, and for pharmacists who must know the safety requirements of drugs. The book is essential for scientists and managers in the pharmaceutical industry who are involved in drug discovery, drug development and decision making in the development process. In particular, the book will be of use to government institutions and committees working on official guidelines for drug evaluation worldwide.
Book Synopsis Synthesis of Best-Seller Drugs by : Ruben Vardanyan
Download or read book Synthesis of Best-Seller Drugs written by Ruben Vardanyan and published by Academic Press. This book was released on 2016-01-07 with total page 870 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesis of Best-Seller Drugs is a key reference guide for all those involved with the design, development, and use of the best-selling drugs. Designed for ease of use, this book provides detailed information on the most popular drugs, using a practical layout arranged according to drug type. Each chapter reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and synthesis. Of high interest to all those who work in the captivating areas of biologically active compounds and medicinal drug synthesis, in particular medicinal chemists, biochemists, and pharmacologists, the book aims to support current research efforts, while also encouraging future developments in this important field. - Describes methods of synthesis, bioactivity and related drugs in key therapeutic areas - Reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and more - Presents a practical layout designed for use as a quick reference tool by those working in drug design, development and implementation
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :0309490111 Total Pages :493 pages Book Rating :4.3/5 (94 download)
Book Synopsis The Promise of Adolescence by : National Academies of Sciences, Engineering, and Medicine
Download or read book The Promise of Adolescence written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-07-26 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adolescenceâ€"beginning with the onset of puberty and ending in the mid-20sâ€"is a critical period of development during which key areas of the brain mature and develop. These changes in brain structure, function, and connectivity mark adolescence as a period of opportunity to discover new vistas, to form relationships with peers and adults, and to explore one's developing identity. It is also a period of resilience that can ameliorate childhood setbacks and set the stage for a thriving trajectory over the life course. Because adolescents comprise nearly one-fourth of the entire U.S. population, the nation needs policies and practices that will better leverage these developmental opportunities to harness the promise of adolescenceâ€"rather than focusing myopically on containing its risks. This report examines the neurobiological and socio-behavioral science of adolescent development and outlines how this knowledge can be applied, both to promote adolescent well-being, resilience, and development, and to rectify structural barriers and inequalities in opportunity, enabling all adolescents to flourish.
Book Synopsis Hormones and Their Receptors in Fish Reproduction by : Philippa Melamed
Download or read book Hormones and Their Receptors in Fish Reproduction written by Philippa Melamed and published by World Scientific. This book was released on 2005 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research on the molecular aspects of fish reproduction has progressedswiftly over the past few years. With the availability of wide-rangingmolecular tools, fish researchers have elucidated many of themolecular mechanisms regulating reproduction which operate in thebrain, pituitary and gonad.
