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Glutamine And Glutamate Mammals
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Book Synopsis Glutamine and Glutamate Mammals by : Elling Kvamme
Download or read book Glutamine and Glutamate Mammals written by Elling Kvamme and published by CRC Press. This book was released on 2018-01-18 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on the joint effort of a great many top scientists, this book covers most aspects of the metabolism and function of glutamine and glutamate in mammals.
Book Synopsis Glutamine and Glutamate Mammals by : Elling Kvamme
Download or read book Glutamine and Glutamate Mammals written by Elling Kvamme and published by CRC Press. This book was released on 2018-01-18 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on the joint effort of a great many top scientists, this book covers most aspects of the metabolism and function of glutamine and glutamate in mammals.
Book Synopsis Glutamine and Glutamate in Mammals by : Elling Kvamme
Download or read book Glutamine and Glutamate in Mammals written by Elling Kvamme and published by . This book was released on 1982 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Glutamine and Glutamate in Mammals by : Elling Kvamme
Download or read book Glutamine and Glutamate in Mammals written by Elling Kvamme and published by CRC PressI Llc. This book was released on 1988 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Glutamine Metabolism in Mammalian Tissues by : D. Häussinger
Download or read book Glutamine Metabolism in Mammalian Tissues written by D. Häussinger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System by : Institute of Medicine
Download or read book Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System written by Institute of Medicine and published by National Academies Press. This book was released on 2011-08-05 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glutamate is the most pervasive neurotransmitter in the central nervous system (CNS). Despite this fact, no validated biological markers, or biomarkers, currently exist for measuring glutamate pathology in CNS disorders or injuries. Glutamate dysfunction has been associated with an extensive range of nervous system diseases and disorders. Problems with how the neurotransmitter glutamate functions in the brain have been linked to a wide variety of disorders, including schizophrenia, Alzheimer's, substance abuse, and traumatic brain injury. These conditions are widespread, affecting a large portion of the United States population, and remain difficult to treat. Efforts to understand, treat, and prevent glutamate-related disorders can be aided by the identification of valid biomarkers. The Institute of Medicine's Forum on Neuroscience and Nervous System Disorders held a workshop on June 21-22, 2010, to explore ways to accelerate the development, validation, and implementation of such biomarkers. Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System: Workshop Summary investigates promising current and emerging technologies, and outlines strategies to procure resources and tools to advance drug development for associated nervous system disorders. Moreover, this report highlights presentations by expert panelists, and the open panel discussions that occurred during the workshop.
Book Synopsis Glutamine and Glutamate Mammals by : Elling Kvamme
Download or read book Glutamine and Glutamate Mammals written by Elling Kvamme and published by CRC Press. This book was released on 2018-01-18 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on the joint effort of a great many top scientists, this book covers most aspects of the metabolism and function of glutamine and glutamate in mammals.
Book Synopsis Regulation of Amino Acid Metabolism in Mammals by : Bernard Schepartz
Download or read book Regulation of Amino Acid Metabolism in Mammals written by Bernard Schepartz and published by W.B. Saunders Company. This book was released on 1973 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Glutamic Acid written by Lloyd J. Filer and published by Raven Press (ID). This book was released on 1979 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Heterogeneity of Cancer Metabolism by : Anne Le
Download or read book The Heterogeneity of Cancer Metabolism written by Anne Le and published by Springer. This book was released on 2018-06-26 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.
Book Synopsis The Glutamate/GABA-Glutamine Cycle by : Arne Schousboe
Download or read book The Glutamate/GABA-Glutamine Cycle written by Arne Schousboe and published by Springer. This book was released on 2016-11-25 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamental biochemical studies of basic brain metabolism focusing on the neuroactive amino acids glutamate and GABA combined with the seminal observation that one of the key enzymes, glutamine synthetase is localized in astroglial cells but not in neurons resulted in the formulation of the term “The Glutamate-Glutamine Cycle.” In this cycle glutamate released from neurons is taken up by surrounding astrocytes, amidated by the action of glutamine synthetase to glutamine which can be transferred back to the neurons. The conversion of glutamate to glutamine is like a stealth technology, hiding the glutamate molecule which would be highly toxic to neurons due to its excitotoxic action. This series of reactions require the concerted and precise interaction of a number of enzymes and plasma membrane transporters, and this volume provides in-depth descriptions of these processes. Obviously such a series of complicated reactions may well be prone to malfunction and therefore neurological diseases are likely to be associated with such malfunction of the enzymes and transporters involved in the cycle. These aspects are also discussed in several chapters of the book. A number of leading experts in neuroscience including intermediary metabolism, enzymology and transporter physiology have contributed to this book which provides comprehensive discussions of these different aspects of the functional importance of the glutamate-glutamine cycle coupling homeostasis of glutamatergic, excitatory neurotransmission to basic aspects of brain energy metabolism. This book will be of particular importance for students as well as professionals interested in these fundamental processes involved in brain function and dysfunction.
Download or read book Glutamate written by Peter J. Roberts and published by John Wiley & Sons. This book was released on 1981 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Mammalian Amino Acid Transport by : D. Häussinger
Download or read book Mammalian Amino Acid Transport written by D. Häussinger and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amino acid transport is a part of each of two larger subjects, amino acid metabolism and the biomembrane transport of various . small molecules and ions. Nevertheless in this volume we treat amino acid transport as more than a fragment of either of these two larger subjects. A more comprehensive approach is justified when we remember two historic and ongoing aspects of the title subject. First, amino acid transport had its beginning and acquired a distinct momentum (even if somewhat interrupted from 1913 until about 1945) as amino acid metabolism with the central and pioneer work of Van Slyke and Meyer in 1913. The reviews in this volume will show that it steadily becomes a larger aspect of amino acid metabolism, broadly perceived. These chapters will show for how many organelles, cells, tissues, organs and organ systems, the transmembrane compartmentations and flows of amino acids play very large parts in their fundamental biological relations. The authors here are tending collectively to evaluate an understanding of amino acid flows across biomernbranes, and the regulation of these flows, as necessary to an ultimate understanding of the full range of development and metabolism. Such an understanding goes far beyond the purely substrate-destabilizing contributions by enzymes, which have often been arbitrarily limited to that conceptual entity, "the cell", and which for so long a splendid time had most of biochemical research attention.
Book Synopsis Military Strategies for Sustainment of Nutrition and Immune Function in the Field by : Institute of Medicine
Download or read book Military Strategies for Sustainment of Nutrition and Immune Function in the Field written by Institute of Medicine and published by National Academies Press. This book was released on 1999-05-13 with total page 722 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every aspect of immune function and host defense is dependent upon a proper supply and balance of nutrients. Severe malnutrition can cause significant alteration in immune response, but even subclinical deficits may be associated with an impaired immune response, and an increased risk of infection. Infectious diseases have accounted for more off-duty days during major wars than combat wounds or nonbattle injuries. Combined stressors may reduce the normal ability of soldiers to resist pathogens, increase their susceptibility to biological warfare agents, and reduce the effectiveness of vaccines intended to protect them. There is also a concern with the inappropriate use of dietary supplements. This book, one of a series, examines the impact of various types of stressors and the role of specific dietary nutrients in maintaining immune function of military personnel in the field. It reviews the impact of compromised nutrition status on immune function; the interaction of health, exercise, and stress (both physical and psychological) in immune function; and the role of nutritional supplements and newer biotechnology methods reported to enhance immune function. The first part of the book contains the committee's workshop summary and evaluation of ongoing research by Army scientists on immune status in special forces troops, responses to the Army's questions, conclusions, and recommendations. The rest of the book contains papers contributed by workshop speakers, grouped under such broad topics as an introduction to what is known about immune function, the assessment of immune function, the effect of nutrition, and the relation between the many and varied stresses encountered by military personnel and their effect on health.
Book Synopsis Glutamine metabolism in mammalian tissues by : Helmut Sies
Download or read book Glutamine metabolism in mammalian tissues written by Helmut Sies and published by . This book was released on 1983 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Metabolism in Cancer by : Thorsten Cramer
Download or read book Metabolism in Cancer written by Thorsten Cramer and published by Springer. This book was released on 2016-08-24 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook presents concise chapters written by internationally respected experts on various important aspects of cancer-associated metabolism, offering a comprehensive overview of the central features of this exciting research field. The discovery that tumor cells display characteristic alterations of metabolic pathways has significantly changed our understanding of cancer: while the first description of tumor-specific changes in cellular energetics was published more than 90 years ago, the causal significance of this observation for the pathogenesis of cancer was only discovered in the post-genome era. The first 10 years of the twenty-first century were characterized by rapid advances in our grasp of the functional role of cancer-specific metabolism as well as the underlying molecular pathways. Various unanticipated interrelations between metabolic alterations and cancer-driving pathways were identified and currently await translation into diagnostic and therapeutic applications. Yet the speed, quantity, and complexity of these new discoveries make it difficult for researchers to keep up to date with the latest developments, an issue this book helps to remedy.
Book Synopsis Amino Acids in Nutrition and Health by : Guoyao Wu
Download or read book Amino Acids in Nutrition and Health written by Guoyao Wu and published by Springer Nature. This book was released on 2021-03-26 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amino acids (AAs) are not only building blocks of protein, but are also signalling molecules as well as regulators of gene expression and the protein phosphorylation cascade. Additionally, AAs are key precursors for syntheses of hormones and low-molecular weight nitrogenous substances with each having enormous biological importance. For example, physiological concentrations of AA metabolites (e.g., nitric oxide, polyamines, glutathione, taurine, thyroid hormones, and serotonin) are required for cell functions. Growing evidence shows that humans and animals have dietary requirements for all proteinogenic AAs. Mammals, birds and fish also have species- and age-dependent needs for some AA-related substances. However, elevated levels of other products (e.g., ammonia, homocysteine, H2S, and asymmetric dimethylarginine) are pathogenic factors for neurological disorders, oxidative stress, and cardiovascular disease. Thus, optimal amounts of AAs and their ratios in diets and circulation are crucial for whole body homeostasis and health. Adequate provision of one or a mixture of functional AAs or metabolites may be beneficial for ameliorating health problems at various stages of the life cycle (e.g., fetal growth restriction, neonatal morbidity and mortality, weaning-associated intestinal dysfunction and wasting syndrome, obesity, diabetes, cardiovascular disease, the metabolic syndrome, and infertility). Dietary supplementation of these nutrients can also optimize the efficiency of metabolic transformations to enhance muscle growth, milk production, and athletic performance, while preventing excess fat deposition and reducing adiposity. Therefore, functional AAs hold great promise in improving the growth, health and well-being of individuals. Chapter 7 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.