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Genomics In Asia
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Book Synopsis Evolutionary Genomics by : Maria Anisimova
Download or read book Evolutionary Genomics written by Maria Anisimova and published by Humana Press. This book was released on 2012-03-08 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Together with early theoretical work in population genetics, the debate on sources of genetic makeup initiated by proponents of the neutral theory made a solid contribution to the spectacular growth in statistical methodologies for molecular evolution. Evolutionary Genomics: Statistical and Computational Methods is intended to bring together the more recent developments in the statistical methodology and the challenges that followed as a result of rapidly improving sequencing technologies. Presented by top scientists from a variety of disciplines, the collection includes a wide spectrum of articles encompassing theoretical works and hands-on tutorials, as well as many reviews with key biological insight. Volume 2 begins with phylogenomics and continues with in-depth coverage of natural selection, recombination, and genomic innovation. The remaining chapters treat topics of more recent interest, including population genomics, -omics studies, and computational issues related to the handling of large-scale genomic data. Written in the highly successful Methods in Molecular BiologyTM series format, this work provides the kind of advice on methodology and implementation that is crucial for getting ahead in genomic data analyses. Comprehensive and cutting-edge, Evolutionary Genomics: Statistical and Computational Methods is a treasure chest of state-of the-art methods to study genomic and omics data, certain to inspire both young and experienced readers to join the interdisciplinary field of evolutionary genomics.
Book Synopsis Genomics In Asia by : Margaret Sleeboom-Faulkner
Download or read book Genomics In Asia written by Margaret Sleeboom-Faulkner and published by Routledge. This book was released on 2012-11-12 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Genomics in Asia" focuses on issues dealing with the development and application of molecular biology and bioengineering technologies in Asian societies and cultures. The workshop on which this book is based aimed to gain an insight into bioethical issues with relation to the dynamics of Asian societies, cultures and religions. It was to generate debate on Asian Genomics and create a basis for comparative research into the relationship between the development and application of modern genetics, cultural values, and local interests in Asian societies. The papers first of all reflect a great variety of bioethical views discussed from the angle of different disciplinary and cultural backgrounds, creating a basis on which a further comparison between different local knowledge systems in relation to genomic practices will be feasible. This book provides insights on research into the social, political and ethical aspects of genomics, and reflects the bioethical experiences of researchers from Japan, China, the Philippines, Thailand, Taiwan, Pakistan, India and Malaysia. The subjects of discussion vary from genetics in China to religious perspectives on cloning and genetic therapy. Themes include the commercial and medical application of new bioengineering technologies, such as the impact of preventive genetic medicine, genetic counselling, genetically modified organisms [GMOs] and stem-cell research on wealth distribution, cultural traditions, social well-being, and political and legal regulations and institutions. In the study of bioengineering in Asia, various perspectives were brought together at a concrete research level. The authors tried to avoid macro-concepts incorporated by dichotomies of East and West and to acquire new insights into the relationship between local knowledge systems and cultures and interests groups on the one hand and the constellation of various interests of scientific research, governments and MNCs on the other.
Book Synopsis The Peopling of East Asia by : Roger Blench
Download or read book The Peopling of East Asia written by Roger Blench and published by Routledge. This book was released on 2005-03-20 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent findings in the fields of East Asian archaeology, linguistics and genetics are collected together here, making this an ideal reference tool for scholars in all disciplines working on the reconstruction of the East Asian past.
Book Synopsis Who We Are and How We Got Here by : David Reich
Download or read book Who We Are and How We Got Here written by David Reich and published by Oxford University Press. This book was released on 2018-03-29 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past few years have seen a revolution in our ability to map whole genome DNA from ancient humans. With the ancient DNA revolution, combined with rapid genome mapping of present human populations, has come remarkable insights into our past. This important new data has clarified and added to our knowledge from archaeology and anthropology, helped resolve long-existing controversies, challenged long-held views, and thrown up some remarkable surprises. The emerging picture is one of many waves of ancient human migrations, so that all populations existing today are mixes of ancient ones, as well as in many cases carrying a genetic component from Neanderthals, and, in some populations, Denisovans. David Reich, whose team has been at the forefront of these discoveries, explains what the genetics is telling us about ourselves and our complex and often surprising ancestry. Gone are old ideas of any kind of racial 'purity', or even deep and ancient divides between peoples. Instead, we are finding a rich variety of mixtures. Reich describes the cutting-edge findings from the past few years, and also considers the sensitivities involved in tracing ancestry, with science sometimes jostling with politics and tradition. He brings an important wider message: that we should celebrate our rich diversity, and recognize that every one of us is the result of a long history of migration and intermixing of ancient peoples, which we carry as ghosts in our DNA. What will we discover next?
Download or read book Fungible Life written by Aihwa Ong and published by Duke University Press. This book was released on 2016-10-13 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Fungible Life Aihwa Ong explores the dynamic world of cutting-edge bioscience research, offering critical insights into the complex ways Asian bioscientific worlds and cosmopolitan sciences are entangled in a tropical environment brimming with the threat of emergent diseases. At biomedical centers in Singapore and China scientists map genetic variants, disease risks, and biomarkers, mobilizing ethnicized "Asian" bodies and health data for genomic research. Their differentiation between Chinese, Indian, and Malay DNA makes fungible Singapore's ethnic-stratified databases that come to "represent" majority populations in Asia. By deploying genomic science as a public good, researchers reconfigure the relationships between objects, peoples, and spaces, thus rendering "Asia" itself as a shifting entity. In Ong's analysis, Asia emerges as a richly layered mode of entanglements, where the population's genetic pasts, anxieties and hopes, shared genetic weaknesses, and embattled genetic futures intersect. Furthermore, her illustration of the contrasting methods and goals of the Biopolis biomedical center in Singapore and BGI Genomics in China raises questions about the future direction of cosmopolitan science in Asia and beyond.
Book Synopsis Genome Analysis: Current Procedures and Applications by : Maria S. Poptsova
Download or read book Genome Analysis: Current Procedures and Applications written by Maria S. Poptsova and published by Caister Academic Press. This book was released on 2019-04-28 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years there have been tremendous achievements made in DNA sequencing technologies and corresponding innovations in data analysis and bioinformatics that have revolutionized the field of genome analysis.In this book, an impressive array of expert authors highlight and review current advances in genome analysis. This volume provides an invaluable, up-to-date and comprehensive overview of the methods currently employed for next-generation sequencing (NGS) data analysis, highlights their problems and limitations, demonstrates the applications and indicates the developing trends in various fields of genome research. The first part of the book is devoted to the methods and applications that arose from, or were significantly advanced by, NGS technologies: the identification of structural variation from DNA-seq data; whole-transcriptome analysis and discovery of small interfering RNAs (siRNAs) from RNA-seq data; motif finding in promoter regions, enhancer prediction and nucleosome sequence code discovery from ChiP-Seq data; identification of methylation patterns in cancer from MeDIP-seq data; transposon identification in NGS data; metagenomics and metatranscriptomics; NGS of viral communities; and causes and consequences of genome instabilities. The second part is devoted to the field of RNA biology with the last three chapters devoted to computational methods of RNA structure prediction including context-free grammar applications.An essential book for everyone involved in sequence data analysis, next-generation sequencing, high-throughput sequencing, RNA structure prediction, bioinformatics and genome analysis.
Book Synopsis Genomics of Cultivated Palms by : V Arunachalam
Download or read book Genomics of Cultivated Palms written by V Arunachalam and published by Elsevier. This book was released on 2011-12-12 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinformatics offers novel tools and resources to analyze plant genomes and genes. The complete genomes of two important commercial palms (dates and oil palm) have recently been sequenced. This offers scope for many computational tools to decipher the synteny, collinearity and common and unique genes of palms. This book reviews the latest developments in this field. Includes the latest information on the molecular breeding and bioinformatics of palms Covers past and current work and future opportunities Written in simple language avoiding technical jargon
Book Synopsis Applied Plant Genomics and Biotechnology by : Palmiro Poltronieri
Download or read book Applied Plant Genomics and Biotechnology written by Palmiro Poltronieri and published by Woodhead Publishing. This book was released on 2015-01-27 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applied plant genomics and biotechnology reviews the recent advancements in the post-genomic era, discussing how different varieties respond to abiotic and biotic stresses, investigating epigenetic modifications and epigenetic memory through analysis of DNA methylation states, applicative uses of RNA silencing and RNA interference in plant physiology and in experimental transgenics, and plants modified to produce high-value pharmaceutical proteins. The book provides an overview of research advances in application of RNA silencing and RNA interference, through Virus-based transient gene expression systems, Virus induced gene complementation (VIGC), Virus induced gene silencing (Sir VIGS, Mr VIGS) Virus-based microRNA silencing (VbMS) and Virus-based RNA mobility assays (VRMA); RNA based vaccines and expression of virus proteins or RNA, and virus-like particles in plants, the potential of virus vaccines and therapeutics, and exploring plants as factories for useful products and pharmaceuticals are topics wholly deepened. The book reviews and discuss Plant Functional Genomic studies discussing the technologies supporting the genetic improvement of plants and the production of plant varieties more resistant to biotic and abiotic stresses. Several important crops are analysed providing a glimpse on the most up-to-date methods and topics of investigation. The book presents a review on current state of GMO, the cisgenesis-derived plants and novel plant products devoid of transgene elements, discuss their regulation and the production of desired traits such as resistance to viruses and disease also in fruit trees and wood trees with long vegetative periods. Several chapters cover aspects of plant physiology related to plant improvement: cytokinin metabolism and hormone signaling pathways are discussed in barley; PARP-domain proteins involved in Stress-Induced Morphogenetic Response, regulation of NAD signaling and ROS dependent synthesis of anthocyanins. Apple allergen isoforms and the various content in different varieties are discussed and approaches to reduce their presence. Euphorbiaceae, castor bean, cassava and Jathropa are discussed at genomic structure, their diseases and viruses, and methods of transformation. Rice genomics and agricultural traits are discussed, and biotechnology for engineering and improve rice varieties. Mango topics are presented with an overview of molecular methods for variety differentiation, and aspects of fruit improvement by traditional and biotechnology methods. Oilseed rape is presented, discussing the genetic diversity, quality traits, genetic maps, genomic selection and comparative genomics for improvement of varieties. Tomato studies are presented, with an overview on the knowledge of the regulatory networks involved in flowering, methods applied to study the tomato genome-wide DNA methylation, its regulation by small RNAs, microRNA-dependent control of transcription factors expression, the development and ripening processes in tomato, genomic studies and fruit modelling to establish fleshy fruit traits of interest; the gene reprogramming during fruit ripening, and the ethylene dependent and independent DNA methylation changes. - provides an overview on the ongoing projects and activities in the field of applied biotechnology - includes examples of different crops and applications to be exploited - reviews and discusses Plant Functional Genomic studies and the future developments in the field - explores the new technologies supporting the genetic improvement of plants
Book Synopsis Revisiting Race in a Genomic Age by : Barbara A. Koenig
Download or read book Revisiting Race in a Genomic Age written by Barbara A. Koenig and published by Rutgers University Press. This book was released on 2008 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essays explore a range of topics that include drug development and the production of race-based therapeutics, the ways in which genetics could contribute to future health disparities, the social implications of ancestry mapping, and the impact of emerging race and genetics research on public policy and the media.
Book Synopsis The Genome Factor by : Dalton Conley
Download or read book The Genome Factor written by Dalton Conley and published by Princeton University Press. This book was released on 2018-11-13 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: "For a century, social scientists have avoided genetics like the plague. But in the past decade, a small but intrepid group of economists, political scientists, and sociologists have harnessed the genomics revolution to paint a more complete picture of human social life than ever before. The Genome Factor describes the latest astonishing discoveries being made at the scientific frontier where genomics and the social sciences intersect. The Genome Factor reveals that there are real genetic differences by racial ancestry--but ones that don't conform to what we call black, white, or Latino. Genes explain a significant share of who gets ahead in society and who does not, but instead of giving rise to a genotocracy, genes often act as engines of mobility that counter social disadvantage. An increasing number of us are marrying partners with similar education levels as ourselves, but genetically speaking, humans are mixing it up more than ever before with respect to mating and reproduction. These are just a few of the many findings presented in this illuminating and entertaining book, which also tackles controversial topics such as genetically personalized education and the future of reproduction in a world where more and more of us are taking advantage of cheap genotyping services like 23andMe to find out what our genes may hold in store for ourselves and our children. The Genome Factor shows how genomics is transforming the social sciences--and how social scientists are integrating both nature and nurture into a unified, comprehensive understanding of human behavior at both the individual and society-wide levels."--
Book Synopsis Past Human Migrations in East Asia by : Alicia Sanchez-Mazas
Download or read book Past Human Migrations in East Asia written by Alicia Sanchez-Mazas and published by Routledge. This book was released on 2008-07-25 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of the prehistory of East Asia is developing very rapidly. In uncovering the story of the flows of human migration that constituted the peopling of East Asia there exists widespread debate about the nature of evidence and the tools for correlating results from different disciplines. Drawing upon the latest evidence in genetics, linguistics and archaeology, this exciting new book examines the history of the peopling of East Asia, and investigates the ways in which we can detect migration, and its different markers in these fields of inquiry. Results from different academic disciplines are compared and reinterpreted in the light of evidence from others to attempt to try and generate consensus on methodology. Taking a broad geographical focus, the book also draws attention to the roles of minority peoples – hitherto underplayed in accounts of the region’s prehistory – such as the Austronesian, Tai-Kadai and Altaic speakers, whose contribution to the regional culture is now becoming accepted. Past Human Migrations in East Asia presents a full picture of the latest research on the peopling of East Asia, and will be of interest to scholars of all disciplines working on the reconstruction of the peopling of East and North East Asia.
Book Synopsis Mien Relations by : Hjorleifur Jonsson
Download or read book Mien Relations written by Hjorleifur Jonsson and published by Cornell University Press. This book was released on 2018-07-05 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thailand's hill tribes have been the object of anthropological research, cultural tourism, and government intervention for a century, in large part because these groups are held to have preserved distinctive ethnic traditions despite their contacts with "modern" culture. Hjorleifur Jonsson rejects the conventional notion that the worlds of traditional peoples are being transformed or undone by the forces of modernity. Among the Mien people of northern Thailand he finds a complex highlander identity that has been shaped by a thousand years of interaction in a multiethnic contact zone. In Mien Relations, Jonsson suggests that as early as the thirteenth century, the growing influence of Chinese and Thai state authority had led to a peculiarly urban understanding of the hinterlands—the forests and the mountains—as an area beyond state control and the rhetoric of civilization. Mountain peoples became understood as a distinct social type, an idea elaborated by government classification systems in the late nineteenth and early twentieth centuries. Their "discovery" by Western anthropologists is, he suggests, merely one more episode influencing Mien identity. Jonsson questions traditional ethnography's focus on fieldwork and personal observation—and its concomitant blindness to political manipulation and to historical formation. Throughout Mien Relations, he revisits long-neglected connections between China and Southeast Asia, combines ancient history and contemporary ethnography, engages with the serious politics of representation without abandoning the quest to write ethnographically about particular communities, and keeps state control in view without assuming its success or coherence.
Book Synopsis The History and Geography of Human Genes by : L L Cavalli-sforza
Download or read book The History and Geography of Human Genes written by L L Cavalli-sforza and published by Princeton University Press. This book was released on 2018-06-05 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hailed as a breakthrough in the understanding of human evolution, The History and Geography of Human Genes offers the first full-scale reconstruction of where human populations originated and the paths by which they spread throughout the world. By mapping the worldwide geographic distribution of genes for over 110 traits in over 1800 primarily aboriginal populations, the authors charted migrations and devised a clock by which to date evolutionary history. This monumental work is now available in a more affordable paperback edition without the myriad illustrations and maps, but containing the full text and partial appendices of the authors' pathbreaking endeavor.
Download or read book Asian Biotech written by Aihwa Ong and published by Duke University Press. This book was released on 2010-11-05 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing the first overview of Asia’s emerging biosciences landscape, this timely and important collection brings together ethnographic case studies on biotech endeavors such as genetically modified foods in China, clinical trials in India, blood collection in Singapore and China, and stem-cell research in Singapore, South Korea, and Taiwan. While biotech policies and projects vary by country, the contributors identify a significant trend toward state entrepreneurialism in biotechnology, and they highlight the ways that political thinking and ethical reasoning are converging around the biosciences. As ascendant nations in a region of postcolonial emergence, with an “uncanny surplus” in population and pandemics, Asian countries treat their populations as sources of opportunity and risk. Biotech enterprises are allied to efforts to overcome past humiliations and restore national identity and political ambition, and they are legitimized as solutions to national anxieties about food supplies, diseases, epidemics, and unknown biological crises in the future. Biotechnological responses to perceived risks stir deep feelings about shared fate, and they crystallize new ethical configurations, often re-inscribing traditional beliefs about ethnicity, nation, and race. As many of the essays in this collection illustrate, state involvement in biotech initiatives is driving the emergence of “biosovereignty,” an increasing pressure for state control over biological resources, commercial health products, corporate behavior, and genetic based-identities. Asian Biotech offers much-needed analysis of the interplay among biotechnologies, economic growth, biosecurity, and ethical practices in Asia. Contributors Vincanne Adams Nancy N. Chen Stefan Ecks Kathleen Erwin Phuoc V. Le Jennifer Liu Aihwa Ong Margaret Sleeboom-Faulkner Kaushik Sunder Rajan Wen-Ching Sung Charis Thompson Ara Wilson
Book Synopsis A History of Ayutthaya by : Chris Baker
Download or read book A History of Ayutthaya written by Chris Baker and published by Cambridge University Press. This book was released on 2017-05-11 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first full history of a great commercial and political center that rose in Asia over almost five centuries.
Book Synopsis Genomics and Health in the Developing World by : Dhavendra Kumar
Download or read book Genomics and Health in the Developing World written by Dhavendra Kumar and published by Oxford University Press. This book was released on 2012-05-11 with total page 1569 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomics and Health in the Developing World provides detailed and comprehensive coverage of population structures, human genomics, and genome variation--with particular emphasis on medical and health issues--in the emerging economies and countries of the developing world. With sections dedicated to fundamtals of genetics and genomics, epidemiology of human disease, biomarkers, comparative genomics, developments in translational genomic medicine, current and future health strategies related to genetic disease, and pertinent legislative and social factors, this volume highlights the importance of utilizing genetics/genomics knowledge to promote and achieve optimal health in the developing world. Grouped by geographic region, the chapters in this volume address: - Inherited disorders in the developing world, including a thorough look at genetic disorders in minority groups of every continent - The progress of diagnostic laboratory genetic testing, prenatal screening, and genetic counseling worldwide - Rising ethical and legal concerns of medical genetics in the developing world - Social, cultural, and religious issues related to genetic diseases across continents Both timely and vastly informative, this book is a unique and comprehensive resource for genetists, clinicians, and public health professionals interested in the social, ethical, economic, and legal matters associated with medical genetics in the developing world.
Book Synopsis Rice Genomics, Genetics and Breeding by : Takuji Sasaki
Download or read book Rice Genomics, Genetics and Breeding written by Takuji Sasaki and published by Springer. This book was released on 2018-02-14 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest advances in rice genomics, genetics and breeding, with a special focus on their importance for rice biology and how they are breathing new life into traditional genetics. Rice is the main staple food for more than half of the world’s population. Accordingly, sustainable rice production is a crucial issue, particularly in Asia and Africa, where the population continues to grow at an alarming rate. The book’s respective chapters offer new and timely perspectives on the synergistic effects of genomics and genetics in novel rice breeding approaches, which can help address the urgent issue of providing enough food for a global population that is expected to reach 9 billion by 2050.
