Genetic Manipulation Of Receptor Expression And Function

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Genetic Manipulation of Receptor Expression and Function

Author : Domenico Accili
Publisher : Wiley-Liss
ISBN 13 :
Total Pages : 278 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Genetic Manipulation of Receptor Expression and Function by : Domenico Accili

Download or read book Genetic Manipulation of Receptor Expression and Function written by Domenico Accili and published by Wiley-Liss. This book was released on 2000-04-13 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our ability to manipulate the genome of living organisms for the elucidation of gene function in vivo has improved dramatically over the last decade. Genetic Manipulation of Receptor Expression and Function provides a comprehensive review of the principles and applications for genetic manipulation of receptor expression and function. By providing the necessary conceptual framework of transgenic and knockout technologies, Genetic Manipulation of Receptor Expression and Function offers a concise and easily accessible analysis for researchers. The material reviews the numerous advances in the field of transgenic technology allowing researchers to alter expression and function in the mouse genome. This volume also: * Provides a roadmap to transgenic and knockout methodology * Includes a detailed explanation of the differences between embryonic stem cells and fertilized zygotes * Clarifies the use of a DNA construct to make a transgenic mouse and a targeting vector for a knockout * Reviews the considerable progress in receptor research * Covers rapidly changing aspects in transgenic mouse technology (such as the generation of transgenic mice using large DNA fragments, the role of modifier genes, the importance of behavioral testing in analyzing disease phenotypes, and the growing role of antisense techniques in studies of gene function) Receptor biochemists, neuroscientists, molecular biologists, cell biologists, and molecular geneticists will find Genetic Manipulation of Receptor Expression and Function a useful guide.

Principles of Gene Manipulation

Author : R. W. Old
Publisher : Univ of California Press
ISBN 13 : 9780520046269
Total Pages : 228 pages
Book Rating : 4.0/5 (462 download)

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Book Synopsis Principles of Gene Manipulation by : R. W. Old

Download or read book Principles of Gene Manipulation written by R. W. Old and published by Univ of California Press. This book was released on 1981 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Safety of Genetically Engineered Foods

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309166152
Total Pages : 254 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Safety of Genetically Engineered Foods by : National Research Council

Download or read book Safety of Genetically Engineered Foods written by National Research Council and published by National Academies Press. This book was released on 2004-07-08 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assists policymakers in evaluating the appropriate scientific methods for detecting unintended changes in food and assessing the potential for adverse health effects from genetically modified products. In this book, the committee recommended that greater scrutiny should be given to foods containing new compounds or unusual amounts of naturally occurring substances, regardless of the method used to create them. The book offers a framework to guide federal agencies in selecting the route of safety assessment. It identifies and recommends several pre- and post-market approaches to guide the assessment of unintended compositional changes that could result from genetically modified foods and research avenues to fill the knowledge gaps.

Genetic Manipulation of the Nervous System

Author :
Publisher : Elsevier
ISBN 13 : 0080532403
Total Pages : 297 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Genetic Manipulation of the Nervous System by :

Download or read book Genetic Manipulation of the Nervous System written by and published by Elsevier. This book was released on 1995-11-24 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroscience Perspectives provides multidisciplinary reviews of topics in one of the most diverse and rapidly advancing fields in the life sciences.Whether you are a new recruit to neuroscience, or an established expert, look to this series for 'one-stop' sources of the historical, physiological, pharmacological, biochemical, molecular biological and therapeutic aspects of chosen research areas.The recent development of Gene Therapy procedures which allow specific genes to be delivered to human patients who lack functional copies of them is of major therapeutic importance. In addition such gene delivery methods can be used in other organisms to define the function of particular genes. These studies are of particular interest in the nervous system where there are many incurable diseases like Alzheimer's and Parkinson's diseases which may benefit from therapies of this kind. Unfortunately gene delivery methods for use in the nervous system have lagged behind those in other systems due to the fact that the methods developed in other systems are often not applicable to cells like neurons which do not divide. This book discusses a wide range of methods which have now been developed to overcome these problems and allow safe and efficient delivery of particular genes to the brain. Methods discussed include virological methods, physical methods (such as liposomes) and the transplantation of genetically modified cells. In a single volume therefore this book provides a complete view of these methods and indicates how they can be applied to the development of therapies for treating previously incurable neurological disorders.

Molecular Biology of the Cell

Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genetic Manipulation of DNA and Protein

Author : David Figurski
Publisher : BoD – Books on Demand
ISBN 13 : 9535109944
Total Pages : 465 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Genetic Manipulation of DNA and Protein by : David Figurski

Download or read book Genetic Manipulation of DNA and Protein written by David Figurski and published by BoD – Books on Demand. This book was released on 2013-02-05 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: This diverse collection of research articles is united by the enormous power of modern molecular genetics. Every author accomplished two objectives: (1) making the field and the research described accessible to a large audience and (2) explaining fully the genetic tools and approaches that were used in the research. One fact stands out - the importance of a genetic approach to addressing a problem. I encourage you to read several chapters. You will feel the excitement of the scientists, and you will learn about an area of research with which you may not be familiar. Perhaps most importantly, you will understand the genetic approaches; and you will appreciate their importance to the research.

Gene Expression and Manipulation in Aquatic Organisms

Author : S. J. Ennion
Publisher : Cambridge University Press
ISBN 13 : 9780521570039
Total Pages : 232 pages
Book Rating : 4.5/5 (7 download)

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Book Synopsis Gene Expression and Manipulation in Aquatic Organisms by : S. J. Ennion

Download or read book Gene Expression and Manipulation in Aquatic Organisms written by S. J. Ennion and published by Cambridge University Press. This book was released on 1996-06-20 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: The techniques of molecular biology offer a powerful means of investigating and controlling the genetic basis of mechanisms operating in living organisms. The development of these techniques in aquatic animals has now reached the stage where important questions relating to growth, development and adaptation to the environment can be addressed at the level of gene expression, and the introduction and expression of novel genes achieved. This volume presents some of the most exciting advances in this rapidly expanding area, with contributions on the evolution of adaptation to low temperature, adaptation to short-term fluctuations in temperature and salinity, gene expression during growth and development, myosin polymorphism and the generation of transgenic fish. As such, it will be of interest to all those working in the fields of marine and freshwater biology and also to those working in aquaculture.

Gene Manipulation and Expression

Author : Robert E. Glass
Publisher : Springer Science & Business Media
ISBN 13 : 9401165653
Total Pages : 567 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Gene Manipulation and Expression by : Robert E. Glass

Download or read book Gene Manipulation and Expression written by Robert E. Glass and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents selected papers from the international symposium on "Gene Manipulation and Expression" held in the Bechyne Castle, in South Bohemia, Czechoslovakia, on September 3 to 7, 1984. The symposium was sponsored by Academician J. Riman, vicepresident of the Czechoslovak Academy of Sci ences and director of the Institute of Molecular Genetics of the Czechoslovak Academy of Sciences, and by corresponding member of the Czechoslovak Academy of Sciences Prof. V. Krumphanzl, president of the Czechoslovak Society for Microbiology and director of the Institute of Microbiology of the Czechoslovak Academy of Sciences, with Dr. K. Mikulik of the same Institute acting as chairman of the Organizing Committee. The book is divided into four parts entitled: (l) Rearrangement of prokaryotic genetic material and DNA cloning vectors; (2) DNA-Dependent RNA polymerase in prokaryotes: structure and function; (3) The role of cAMP in gene expression; (4) Translational control of gene expression. We wish to thank all participants who con tributed to this volume. We should also like to express our deep gratitude to Drs. I. Janda and J. Weiser, both of the Institute of Microbiology of the Czechoslovak Academy of Sciences, for their invaluable help in the editorial work and Mrs. J. Pistorova for patiently retyping all the manu scripts

Principles of Gene Manipulation and Genomics

Author : Sandy B. Primrose
Publisher : John Wiley & Sons
ISBN 13 : 1405135441
Total Pages : 675 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Principles of Gene Manipulation and Genomics by : Sandy B. Primrose

Download or read book Principles of Gene Manipulation and Genomics written by Sandy B. Primrose and published by John Wiley & Sons. This book was released on 2006-02-10 with total page 675 pages. Available in PDF, EPUB and Kindle. Book excerpt: The increasing integration between gene manipulation and genomics is embraced in this new book, Principles of Gene Manipulation and Genomics, which brings together for the first time the subjects covered by the best-selling books Principles of Gene Manipulation and Principles of Genome Analysis & Genomics. Comprehensively revised, updated and rewritten to encompass within one volume, basic and advanced gene manipulation techniques, genome analysis, genomics, transcriptomics, proteomics and metabolomics Includes two new chapters on the applications of genomics An accompanying website - www.blackwellpublishing.com/primrose - provides instructional materials for both student and lecturer use, including multiple choice questions, related websites, and all the artwork in a downloadable format. An essential reference for upper level undergraduate and graduate students of genetics, genomics, molecular biology and recombinant DNA technology.

Experimental Manipulation of Gene Expression

Author : Masayori Inouye
Publisher : Academic Press
ISBN 13 : 1483273970
Total Pages : 330 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Experimental Manipulation of Gene Expression by : Masayori Inouye

Download or read book Experimental Manipulation of Gene Expression written by Masayori Inouye and published by Academic Press. This book was released on 2014-06-28 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experimental Manipulation of Gene Expression discusses a wide range of host systems in which to clone and express a gene of interest. The aims are for readers to quickly learn the versatility of the systems and obtain an overview of the technology involved in the manipulation of gene expression. Furthermore, it is hoped that the reader will learn enough from the various approaches to be able to develop systems and to arrange for a gene of particular interest to express in a particular system. The book opens with a chapter on the design and construction of a plasmid vector system used to achieve high-level expression of a particular phage regulatory protein normally found in minute amounts in a phage-infected bacterial cell. This is followed by separate chapters on topics such as high-level expression vectors that utilize efficient Escherichia coli lipoprotein promoter as well as various other portions of the lipoprotein gene Ipp; DNA cloning systems for streptomycetes; and the design and application of vectors for high-level, inducible synthesis of the product of a cloned gene in yeast.

New Directions for Biosciences Research in Agriculture

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309035422
Total Pages : 136 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis New Directions for Biosciences Research in Agriculture by : National Research Council

Download or read book New Directions for Biosciences Research in Agriculture written by National Research Council and published by National Academies Press. This book was released on 1985-01-01 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authored by an integrated committee of plant and animal scientists, this review of newer molecular genetic techniques and traditional research methods is presented as a compilation of high-reward opportunities for agricultural research. Directed to the Agricultural Research Service and the agricultural research community at large, the volume discusses biosciences research in genetic engineering, animal science, plant science, and plant diseases and insect pests. An optimal climate for productive research is discussed.

Genetic Engineering of Plants

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309034345
Total Pages : 97 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Genetic Engineering of Plants by : National Research Council

Download or read book Genetic Engineering of Plants written by National Research Council and published by National Academies Press. This book was released on 1984-02-01 with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The book...is, in fact, a short text on the many practical problems...associated with translating the explosion in basic biotechnological research into the next Green Revolution," explains Economic Botany. The book is "a concise and accurate narrative, that also manages to be interesting and personal...a splendid little book." Biotechnology states, "Because of the clarity with which it is written, this thin volume makes a major contribution to improving public understanding of genetic engineering's potential for enlarging the world's food supply...and can be profitably read by practically anyone interested in application of molecular biology to improvement of productivity in agriculture."

Testicular Function: From Gene Expression to Genetic Manipulation

Author : Mario Stefanini
Publisher : Springer Science & Business Media
ISBN 13 : 3662036711
Total Pages : 356 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Testicular Function: From Gene Expression to Genetic Manipulation by : Mario Stefanini

Download or read book Testicular Function: From Gene Expression to Genetic Manipulation written by Mario Stefanini and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the text of the plenary lectures given by internationally recognized experts in the field of gametogenesis and endocrinology at the 10th European Workshop on Molecular and Cellular Endocrinology of the Testis. Topics include spermatogonial transplantation, germ stem cell biology, regulation of meiosis and spermiogenesis, growth factors, cell signaling and transduction, steriodogenesis, androgen-regulated genes, sperm activation and sperm factors active at fertilization. The present volume pays particular attention to the use of genetically manipulated animal models in the study of the regulation of spermatogenesis and testicular functions.

Gene Expression

Author : M. Karin
Publisher : Springer Science & Business Media
ISBN 13 : 1468468111
Total Pages : 313 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Gene Expression by : M. Karin

Download or read book Gene Expression written by M. Karin and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first volume in a new series Progress in Gene Expres sion. The control of gene expression is a central-most topic in molecular biology as it deals with the utilization and regulation of gene informa tion. As we see huge efforts mounting all over the developed world to understand the structure and organization of several complex eukaryotic genomes in the form of Gene Projects and Genome Centers, we have to remember that without understanding the basic mechanisms that gov ern the use of genetic information, much of this effort will not be very productive. Fortunately, however, research during the past seven years on the mechanisms that control gene expression in eukaryotes has been extremely successful in generating a wealth of information on the basic strategies of transcriptional control. (Although regulation of gene ex pression is exerted at many different levels, much of the emphasis in this series will be on transcriptional control. A future volume, however, will deal with other levels of regulation). The progress in understanding the control of eukaryotic transcription can only be appreciated by realizing that seven years ago we did not know the primary structure of a single sequence specific transcriptional activator, and those whose primary structures were available (e. g. , homeo domain proteins) were not yet recognized to function in this capacity.

Plant Biotechnology

Author : Adrian Slater
Publisher : OUP Oxford
ISBN 13 : 0199282617
Total Pages : 401 pages
Book Rating : 4.1/5 (992 download)

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Book Synopsis Plant Biotechnology by : Adrian Slater

Download or read book Plant Biotechnology written by Adrian Slater and published by OUP Oxford. This book was released on 2008-03-27 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant Biotechnology presents a balanced, objective exploration of the technology behind genetic manipulation, and its application to the growth and cultivation of plants. The book describes the techniques underpinning genetic manipulation and makes extensive use of case studies to illustrate how this influential tool is used in practice.

An Introduction to Molecular Medicine and Gene Therapy

Author : Thomas F. Kresina
Publisher : John Wiley & Sons
ISBN 13 : 0471461040
Total Pages : 408 pages
Book Rating : 4.4/5 (714 download)

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Book Synopsis An Introduction to Molecular Medicine and Gene Therapy by : Thomas F. Kresina

Download or read book An Introduction to Molecular Medicine and Gene Therapy written by Thomas F. Kresina and published by John Wiley & Sons. This book was released on 2004-03-24 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Introduction to Molecular Medicine and Gene Therapy Edited by Thomas F. Kresina, Ph.D. Gene therapy, or the use of genetic manipulation for disease treatment, is derived from advances in genetics, molecular biology, clinical medicine, and human genomics. Molecular medicine, the application of molecular biological techniques to disease treatment and diagnosis, is derived from the development of human organ transplantation, pharmacotherapy, and elucidation of the human genome. An Introduction to Molecular Medicine and Gene Therapy provides a basis for interpreting new clinical and basic research findings in the areas of cloning, gene transfer, and targeting; the applications of genetic medicine to clinical conditions; ethics and governmental regulations; and the burgeoning fields of genomics, biotechnology, and bioinformatics. By dividing the material into three sections - an introduction to basic science, a review of clinical applications, and a discussion of the evolving issues related to gene therapy and molecular medicine-this comprehensive manual describes the basic approaches to the broad range of actual and potential genetic-based therapies. In addition, An Introduction to Molecular Medicine and Gene Therapy: * Covers new frontiers in gene therapy, animal models, vectors, gene targeting, and ethical/legal considerations * Provides organ-based reviews of current studies in gene therapy for monogenetic, multifactoral or polygenic disorders, and infectious diseases * Includes bold-faced terms, key concepts, summaries, and lists of helpful references by subject in each chapter * Contains appendices on commercial implications and a review of the history of gene therapy This textbook offers a clear, concise writing style, drawing upon the expertise of the authors, all renowned researchers in their respective specialties of molecular medicine. Researchers in genetics and molecular medicine will all find An Introduction to Molecular Medicine and Gene Therapy to be an essential guide to the rapidly evolving field of gene therapy and its applications in molecular medicine.

An Introduction to Genetic Engineering

Author : Desmond S. T. Nicholl
Publisher : Cambridge University Press
ISBN 13 : 9780521004718
Total Pages : 308 pages
Book Rating : 4.0/5 (47 download)

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Book Synopsis An Introduction to Genetic Engineering by : Desmond S. T. Nicholl

Download or read book An Introduction to Genetic Engineering written by Desmond S. T. Nicholl and published by Cambridge University Press. This book was released on 2002-02-07 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: The author presents a basic introduction to the world of genetic engineering. Copyright © Libri GmbH. All rights reserved.