Genes Germs And Medicine The Life Of Joshua Lederberg

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Genes, Germs And Medicine: The Life Of Joshua Lederberg

Author : Jan Sapp
Publisher : World Scientific
ISBN 13 : 9811225494
Total Pages : 424 pages
Book Rating : 4.8/5 (112 download)

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Book Synopsis Genes, Germs And Medicine: The Life Of Joshua Lederberg by : Jan Sapp

Download or read book Genes, Germs And Medicine: The Life Of Joshua Lederberg written by Jan Sapp and published by World Scientific. This book was released on 2021-02-23 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genes, Germs and Medicine explores the development of modern biomedical science in the United States through the life of one of the Twentieth Century's most influential scientists.Joshua Lederberg was a scientific renaissance man. He and his collaborators founded the field of bacterial genetics, and he was awarded the Nobel Prize at the age of 33 (the second youngest in history). He helped to lay the foundations for genetic engineering, made fundamental revisions to immunological and evolutionary theory, and developed medical genetics. He initiated the search for extraterrestrial microbial life, developed artificial intelligence, and was a visionary of the Digital Age. Lederberg coined some of the central terms of modern biology: plasmid, transduction, exobiology, euphenics and microbiome.A complex humanist who spoke out for social justice, Lederberg confronted racism, and denied a gene-centered view of humans. Pondering our social evolution outside of nature, he forewarned of the complex ethical issues arising from bioengineering. He sounded the alarm about coming pandemics at a time when few would listen, and warned of the peril of biowarfare and strove to prevent it. Lederberg was a man with a deep sense of social and intellectual responsibility, a trusted advisor to eight presidential administrations.

Digitizing Diagnosis

Author : Andrew S. Lea
Publisher : JHU Press
ISBN 13 : 1421446812
Total Pages : 255 pages
Book Rating : 4.4/5 (214 download)

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Book Synopsis Digitizing Diagnosis by : Andrew S. Lea

Download or read book Digitizing Diagnosis written by Andrew S. Lea and published by JHU Press. This book was released on 2023-07-25 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This is the first book-length account of early efforts to computerize medical diagnosis. It explores how these efforts produced and interacted with certain professional tensions, disease constructions, personal identities, cultural ideals, economic interests, and material practices. The book offers a historical account that raises pressing questions, problems, and challenges that must be addressed as we work to harness artificial intelligence for the benefit of the medical profession and its patients"--

Bulletin of the Atomic Scientists

Author :
Publisher :
ISBN 13 :
Total Pages : 48 pages
Book Rating : 4./5 ( download)

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Book Synopsis Bulletin of the Atomic Scientists by :

Download or read book Bulletin of the Atomic Scientists written by and published by . This book was released on 1966-10 with total page 48 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Bulletin of the Atomic Scientists is the premier public resource on scientific and technological developments that impact global security. Founded by Manhattan Project Scientists, the Bulletin's iconic "Doomsday Clock" stimulates solutions for a safer world.

Good Germs, Bad Germs

Author : Jessica Snyder Sachs
Publisher : Macmillan + ORM
ISBN 13 : 1429923296
Total Pages : 410 pages
Book Rating : 4.4/5 (299 download)

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Book Synopsis Good Germs, Bad Germs by : Jessica Snyder Sachs

Download or read book Good Germs, Bad Germs written by Jessica Snyder Sachs and published by Macmillan + ORM. This book was released on 2008-09-30 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Making Peace with Microbes Public sanitation and antibiotic drugs have brought about historic increases in the human life span; they have also unintentionally produced new health crises by disrupting the intimate, age-old balance between humans and the microorganisms that inhabit our bodies and our environment. As a result, antibiotic resistance now ranks among the gravest medical problems of modern times. Good Germs, Bad Germs addresses not only this issue but also what has become known as the "hygiene hypothesis"— an argument that links the over-sanitation of modern life to now-epidemic increases in immune and other disorders. In telling the story of what went terribly wrong in our war on germs, Jessica Snyder Sachs explores our emerging understanding of the symbiotic relationship between the human body and its resident microbes—which outnumber its human cells by a factor of nine to one! The book also offers a hopeful look into a future in which antibiotics will be designed and used more wisely, and beyond that, to a day when we may replace antibacterial drugs and cleansers with bacterial ones—each custom-designed for maximum health benefits.

The Science of Human Perfection

Author : Nathaniel Comfort
Publisher : Yale University Press
ISBN 13 : 0300188870
Total Pages : 371 pages
Book Rating : 4.3/5 (1 download)

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Book Synopsis The Science of Human Perfection by : Nathaniel Comfort

Download or read book The Science of Human Perfection written by Nathaniel Comfort and published by Yale University Press. This book was released on 2012-09-25 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: Almost daily we hear news stories, advertisements, and scientific reports that promise genetic medicine will make us live longer, enable doctors to identify and treat diseases before they start, and individualize our medical care. But surprisingly, a century ago eugenicists were making the same promises. The Science of Human Perfection traces the history of the promises of medical genetics and of the medical dimension of eugenics. The book also considers social and ethical issues that cast troublesome shadows over these fields./divDIV DIVKeeping his focus on America, science historian Nathaniel Comfort introduces the community of scientists, physicians, and public health workers who have contributed to the development of medical genetics from the nineteenth century to today. He argues that medical genetics is closely related to eugenics, and indeed the two cannot be fully understood separately. He also carefully examines how the desire to relieve suffering and to improve ourselves genetically, though noble, may be subverted. History makes clear that as patients and consumers we must take ownership of genetic medicine, using it intelligently, knowledgeably, and skeptically, lest pernicious interests trump our own./div

Microbial Evolution and Co-Adaptation

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309131219
Total Pages : 330 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Microbial Evolution and Co-Adaptation by : Institute of Medicine

Download or read book Microbial Evolution and Co-Adaptation written by Institute of Medicine and published by National Academies Press. This book was released on 2009-05-10 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Joshua Lederberg - scientist, Nobel laureate, visionary thinker, and friend of the Forum on Microbial Threats - died on February 2, 2008. It was in his honor that the Institute of Medicine's Forum on Microbial Threats convened a public workshop on May 20-21, 2008, to examine Dr. Lederberg's scientific and policy contributions to the marketplace of ideas in the life sciences, medicine, and public policy. The resulting workshop summary, Microbial Evolution and Co-Adaptation, demonstrates the extent to which conceptual and technological developments have, within a few short years, advanced our collective understanding of the microbiome, microbial genetics, microbial communities, and microbe-host-environment interactions.

Biomedical Computing

Author : Joseph A. November
Publisher : JHU Press
ISBN 13 : 1421406659
Total Pages : 361 pages
Book Rating : 4.4/5 (214 download)

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Book Synopsis Biomedical Computing by : Joseph A. November

Download or read book Biomedical Computing written by Joseph A. November and published by JHU Press. This book was released on 2012-06-01 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Winner of the Computer History Museum Prize of the Special Interest Group: Computers, Information, and Society Imagine biology and medicine today without computers. What would laboratory work be like if electronic databases and statistical software did not exist? Would disciplines like genomics even be feasible if we lacked the means to manage and manipulate huge volumes of digital data? How would patients fare in a world absent CT scans, programmable pacemakers, and computerized medical records? Today, computers are a critical component of almost all research in biology and medicine. Yet, just fifty years ago, the study of life was by far the least digitized field of science, its living subject matter thought too complex and dynamic to be meaningfully analyzed by logic-driven computers. In this long-overdue study, historian Joseph November explores the early attempts, in the 1950s and 1960s, to computerize biomedical research in the United States. Computers and biomedical research are now so intimately connected that it is difficult to imagine when such critical work was offline. Biomedical Computing transports readers back to such a time and investigates how computers first appeared in the research lab and doctor's office. November examines the conditions that made possible the computerization of biology—including strong technological, institutional, and political support from the National Institutes of Health—and shows not only how digital technology transformed the life sciences but also how the intersection of the two led to important developments in computer architecture and software design. The history of this phenomenon has been only vaguely understood. November's thoroughly researched and lively study makes clear for readers the motives behind computerizing the study of life and how that technology profoundly affects biomedical research today.

The Gene

Author : Siddhartha Mukherjee
Publisher : Simon and Schuster
ISBN 13 : 1476733538
Total Pages : 624 pages
Book Rating : 4.4/5 (767 download)

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Book Synopsis The Gene by : Siddhartha Mukherjee

Download or read book The Gene written by Siddhartha Mukherjee and published by Simon and Schuster. This book was released on 2016-05-17 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History Now includes an excerpt from Siddhartha Mukherjee’s new book Song of the Cell! From the Pulitzer Prize–winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). “Sid Mukherjee has the uncanny ability to bring together science, history, and the future in a way that is understandable and riveting, guiding us through both time and the mystery of life itself.” —Ken Burns “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).

Biotechnology and Genetic Engineering

Author : Kathy Wilson Peacock
Publisher : Infobase Publishing
ISBN 13 : 1438130600
Total Pages : 369 pages
Book Rating : 4.4/5 (381 download)

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Book Synopsis Biotechnology and Genetic Engineering by : Kathy Wilson Peacock

Download or read book Biotechnology and Genetic Engineering written by Kathy Wilson Peacock and published by Infobase Publishing. This book was released on 2010 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explains why biotechnology is a relevant and volatile issues. Begins with a history of biotechnology and its effect on agriculture, medicine, and the environment. Equal space is devoted to discussing the efforts of human-rights advocates, animal-rights advocates, and environmentalists to create definitive governmental regulations for this budding industry.

Pleased to Meet Me

Author : Bill Sullivan
Publisher : National Geographic Books
ISBN 13 : 1426220561
Total Pages : 340 pages
Book Rating : 4.4/5 (262 download)

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Book Synopsis Pleased to Meet Me by : Bill Sullivan

Download or read book Pleased to Meet Me written by Bill Sullivan and published by National Geographic Books. This book was released on 2019-08-06 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why are you attracted to a certain "type?" Why are you a morning person? Why do you vote the way you do? From a witty new voice in popular science comes a clever, life-changing look at what makes you you. "I can't believe I just said that." "What possessed me to do that?" "What's wrong with me?" We're constantly seeking answers to these fundamental human questions, and now, science has the answers. The foods we enjoy, the people we love, the emotions we feel, and the beliefs we hold can all be traced back to our DNA, germs, and environment. This witty, colloquial book is popular science at its best, describing in everyday language how genetics, epigenetics, microbiology, and psychology work together to influence our personality and actions. Mixing cutting-edge research and relatable humor, Pleased to Meet Me is filled with fascinating insights that shine a light on who we really are--and how we might become our best selves.

Pioneers In Microbiology: The Human Side Of Science

Author : King-thom Chung
Publisher : World Scientific
ISBN 13 : 9813200383
Total Pages : 599 pages
Book Rating : 4.8/5 (132 download)

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Book Synopsis Pioneers In Microbiology: The Human Side Of Science by : King-thom Chung

Download or read book Pioneers In Microbiology: The Human Side Of Science written by King-thom Chung and published by World Scientific. This book was released on 2017-08-23 with total page 599 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pasteurization, penicillin, Koch's postulates, and gene coding. These discoveries and inventions are vital yet commonplace in modern life, but were radical when first introduced to the public and academia. In this book, the life and times of leading pioneers in microbiology are discussed in vivid detail, focusing on the background of each discovery and the process in which they were developed — sometimes by accident or sheer providence.

The Microbial Challenge

Author : Robert I. Krasner
Publisher : Jones & Bartlett Publishers
ISBN 13 : 1449673333
Total Pages : 580 pages
Book Rating : 4.4/5 (496 download)

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Book Synopsis The Microbial Challenge by : Robert I. Krasner

Download or read book The Microbial Challenge written by Robert I. Krasner and published by Jones & Bartlett Publishers. This book was released on 2014 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbes play a highly significant role in our daily lives as agents of infectious disease and are a major public health concern. The third edition of The Microbial Challenge: A Public Health Perspective addresses this topic and has been extensively revised and updated with the latest data in a fast-paced field. It focuses on human-microbe interactions and considers bacterial, viral, prion, protozoan, fungal and helminthic (worm) diseases. A chapter on beneficial aspects of microbes makes it clear that not all microbes are disease producers and that microbes are necessary for the sustenance of life on Earth. The response of the immune system, concepts of epidemiology, and measures of control from the individual to the international level to thwart potentially life-threatening epidemics are described. Sections on fungi and fungal diseases are new. The third edition includes new and contemporary information on vaccinations, antibiotic resistant microbes, practical disinfection information, virotherapy and emerging diseases. New boxes throughout the text feature items of human interest such as big and bizarre viruses, probiotics, rats, and synthetic biology. Ancillary instructor and student resources have been updated and expanded including the end of the chapter Self Evaluations. New and Key Features of the Third Edition: -New end-of-chapter questions included in every chapter. -A wealth of new feature boxes add a real-world perspective to the topics at hand. -New data on virotherapy and prions as infectious agents -New and updated statistics and data tables included throughout the text -Includes the latest on emerging and reemerging infectious diseases as major health problems

Collecting Experiments

Author : Bruno J. Strasser
Publisher : University of Chicago Press
ISBN 13 : 022663504X
Total Pages : 421 pages
Book Rating : 4.2/5 (266 download)

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Book Synopsis Collecting Experiments by : Bruno J. Strasser

Download or read book Collecting Experiments written by Bruno J. Strasser and published by University of Chicago Press. This book was released on 2019-06-04 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Databases have revolutionized nearly every aspect of our lives. Information of all sorts is being collected on a massive scale, from Google to Facebook and well beyond. But as the amount of information in databases explodes, we are forced to reassess our ideas about what knowledge is, how it is produced, to whom it belongs, and who can be credited for producing it. Every scientist working today draws on databases to produce scientific knowledge. Databases have become more common than microscopes, voltmeters, and test tubes, and the increasing amount of data has led to major changes in research practices and profound reflections on the proper professional roles of data producers, collectors, curators, and analysts. Collecting Experiments traces the development and use of data collections, especially in the experimental life sciences, from the early twentieth century to the present. It shows that the current revolution is best understood as the coming together of two older ways of knowing—collecting and experimenting, the museum and the laboratory. Ultimately, Bruno J. Strasser argues that by serving as knowledge repositories, as well as indispensable tools for producing new knowledge, these databases function as digital museums for the twenty-first century.

The Cambridge History of Medicine

Author : Roy Porter
Publisher : Cambridge University Press
ISBN 13 : 0521864267
Total Pages : 11 pages
Book Rating : 4.5/5 (218 download)

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Book Synopsis The Cambridge History of Medicine by : Roy Porter

Download or read book The Cambridge History of Medicine written by Roy Porter and published by Cambridge University Press. This book was released on 2006-06-05 with total page 11 pages. Available in PDF, EPUB and Kindle. Book excerpt: Against the backdrop of unprecedented concern for the future of health care, 'The Cambridge History of Medicine' surveys the rise of medicine in the West from classical times to the present. Covering both the social and scientific history of medicine, this volume traces the chronology of key developments and events.

Essential Microbiology

Author : Stuart Hogg
Publisher : John Wiley & Sons
ISBN 13 : 1119978912
Total Pages : 534 pages
Book Rating : 4.1/5 (199 download)

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Book Synopsis Essential Microbiology by : Stuart Hogg

Download or read book Essential Microbiology written by Stuart Hogg and published by John Wiley & Sons. This book was released on 2013-06-10 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential Microbiology 2nd Edition is a fully revised comprehensive introductory text aimed at students taking a first course in the subject. It provides an ideal entry into the world of microorganisms, considering all aspects of their biology (structure, metabolism, genetics), and illustrates the remarkable diversity of microbial life by devoting a chapter to each of the main taxonomic groupings. The second part of the book introduces the reader to aspects of applied microbiology, exploring the involvement of microorganisms in areas as diverse as food and drink production, genetic engineering, global recycling systems and infectious disease. Essential Microbiology explains the key points of each topic but avoids overburdening the student with unnecessary detail. Now in full colour it makes extensive use of clear line diagrams to clarify sometimes difficult concepts or mechanisms. A companion web site includes further material including MCQs, enabling the student to assess their understanding of the main concepts that have been covered. This edition has been fully revised and updated to reflect the developments that have occurred in recent years and includes a completely new section devoted to medical microbiology. Students of any life science degree course will find this a concise and valuable introduction to microbiology.

Snyder and Champness Molecular Genetics of Bacteria

Author : Tina M. Henkin
Publisher : John Wiley & Sons
ISBN 13 : 1555819753
Total Pages : 642 pages
Book Rating : 4.5/5 (558 download)

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Book Synopsis Snyder and Champness Molecular Genetics of Bacteria by : Tina M. Henkin

Download or read book Snyder and Champness Molecular Genetics of Bacteria written by Tina M. Henkin and published by John Wiley & Sons. This book was released on 2020-10-27 with total page 642 pages. Available in PDF, EPUB and Kindle. Book excerpt: The single most comprehensive and authoritative textbook on bacterial molecular genetics Snyder & Champness Molecular Genetics of Bacteria is a new edition of a classic text, updated to address the massive advances in the ﬁeld of bacterial molecular genetics and retitled as homage to the founding authors. In an era experiencing an avalanche of new genetic sequence information, this updated edition presents important experiments and advanced material relevant to current applications of molecular genetics, including conclusions from and applications of genomics; the relationships among recombination, replication, and repair and the importance of organizing sequences in DNA; the mechanisms of regulation of gene expression; the newest advances in bacterial cell biology; and the coordination of cellular processes during the bacterial cell cycle. The topics are integrated throughout with biochemical, genomic, and structural information, allowing readers to gain a deeper understanding of modern bacterial molecular genetics and its relationship to other ﬁelds of modern biology. Although the text is centered on the most-studied bacteria, Escherichia coli and Bacillus subtilis, many examples are drawn from other bacteria of experimental, medical, ecological, and biotechnological importance. The book's many useful features include Text boxes to help students make connections to relevant topics related to other organisms, including humans A summary of main points at the end of each chapter Questions for discussion and independent thought A list of suggested readings for background and further investigation in each chapter Fully illustrated with detailed diagrams and photos in full color A glossary of terms highlighted in the text While intended as an undergraduate or beginning graduate textbook, Molecular Genetics of Bacteria is an invaluable reference for anyone working in the ﬁelds of microbiology, genetics, biochemistry, bioengineering, medicine, molecular biology, and biotechnology. "This is a marvelous textbook that is completely up-to-date and comprehensive, but not overwhelming. The clear prose and excellent ﬁgures make it ideal for use in teaching bacterial molecular genetics." —Caroline Harwood, University of Washington

The New Foundations of Evolution

Author : Jan Sapp
Publisher : Oxford University Press
ISBN 13 : 0199889171
Total Pages : 765 pages
Book Rating : 4.1/5 (998 download)

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Book Synopsis The New Foundations of Evolution by : Jan Sapp

Download or read book The New Foundations of Evolution written by Jan Sapp and published by Oxford University Press. This book was released on 2009-07-24 with total page 765 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the story of a profound revolution in the way biologists explore life's history, understand its evolutionary processes, and reveal its diversity. It is about life's smallest entities, deepest diversity, and greatest cellular biomass: the microbiosphere. Jan Sapp introduces us to a new field of evolutionary biology and a new brand of molecular evolutionists who descend to the foundations of evolution on Earth to explore the origins of the genetic system and the primary life forms from which all others have emerged. In so doing, he examines-from Lamarck to the present-the means of pursuing the evolution of complexity, and of depicting the greatest differences among organisms. The New Foundations of Evolution takes us into a world that classical evolutionists could never have imagined: a deep phylogeny based on three domains of life and multiple kingdoms, and created by mechanisms very unlike those considered by Darwin and his followers. Evolution by leaps seems to occur regularly in the microbial world where molecular evolutionists have shown the inheritance of acquired genes and genomes are major modes of evolutionary innovation. Revisiting the history of microbiology for the first time from the perspective of evolutionary biology, Sapp shows why classical Darwinian conceptions centering on questions of the origin of species were forged without a microbial foundation, why classical microbiologists considered it impossible to know the course of evolution, and classical molecular biologists considered the evolution of the molecular genetic system to be beyond understanding. In telling this stirring story of scientific iconoclasm, this book elucidates how the new evolutionary biology arose, what methods and assumptions underpin it, and the fiery controversies that continue to shape biologists' understanding of the foundations of evolution today.