Gene Machines

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Gene Machine

Author : Venki Ramakrishnan
Publisher : Basic Books
ISBN 13 : 046509337X
Total Pages : 290 pages
Book Rating : 4.4/5 (65 download)

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Book Synopsis Gene Machine by : Venki Ramakrishnan

Download or read book Gene Machine written by Venki Ramakrishnan and published by Basic Books. This book was released on 2018-11-06 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Nobel Prize-winning biologist tells the riveting story of his race to discover the inner workings of biology's most important molecule "Ramakrishnan's writing is so honest, lucid and engaging that I could not put this book down until I had read to the very end." -- Siddhartha Mukherjee, author of The Emperor of All Maladies and The Gene Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome -- an enormous molecular machine made up of a million atoms -- that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases. But this is also a human story of Ramakrishnan's unlikely journey, from his first fumbling experiments in a biology lab to being the dark horse in a fierce competition with some of the world's best scientists. In the end, Gene Machine is a frank insider's account of the pursuit of high-stakes science.

Gene Machines

Author : Fran Balkwill
Publisher : CSHL Press
ISBN 13 : 9780879696115
Total Pages : 36 pages
Book Rating : 4.6/5 (961 download)

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Book Synopsis Gene Machines by : Fran Balkwill

Download or read book Gene Machines written by Fran Balkwill and published by CSHL Press. This book was released on 2002 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt: Summary: An introduction to how genes work, including basic information about cloning and gene therapy.

Mother Earth and the Gene Machines

Author : A. Carlson Whalen
Publisher : A. Carlson Whalen
ISBN 13 : 9780533153398
Total Pages : 308 pages
Book Rating : 4.1/5 (533 download)

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Book Synopsis Mother Earth and the Gene Machines by : A. Carlson Whalen

Download or read book Mother Earth and the Gene Machines written by A. Carlson Whalen and published by A. Carlson Whalen. This book was released on 2006-08 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Gene Machine

Author : Bonnie Rochman
Publisher : Scientific American / Farrar, Straus and Giroux
ISBN 13 : 0374713960
Total Pages : 289 pages
Book Rating : 4.3/5 (747 download)

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Book Synopsis The Gene Machine by : Bonnie Rochman

Download or read book The Gene Machine written by Bonnie Rochman and published by Scientific American / Farrar, Straus and Giroux. This book was released on 2017-02-28 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: A sharp-eyed exploration of the promise and peril of having children in an age of genetic tests and interventions Is screening for disease in an embryo a humane form of family planning or a slippery slope toward eugenics? Should doctors tell you that your infant daughter is genetically predisposed to breast cancer? If tests revealed that your toddler has a genetic mutation whose significance isn’t clear, would you want to know? In The Gene Machine, the award-winning journalist Bonnie Rochman deftly explores these hot-button questions, guiding us through the new frontier of gene technology and how it is transforming medicine, bioethics, health care, and the factors that shape a family. Rochman tells the stories of scientists working to unlock the secrets of the human genome; genetic counselors and spiritual advisers guiding mothers and fathers through life-changing choices; and, of course, parents (including Rochman herself) grappling with revelations that are sometimes joyous, sometimes heartbreaking, but always profound. She navigates the dizzying and constantly expanding array of prenatal and postnatal tests, from carrier screening to genome sequencing, while considering how access to more tests is altering perceptions of disability and changing the conversation about what sort of life is worth living and who draws the line. Along the way, she highlights the most urgent ethical quandary: Is this technology a triumph of modern medicine or a Pandora’s box of possibilities? Propelled by human narratives and meticulously reported, The Gene Machine is both a scientific road map and a meditation on our power to shape the future. It is a book that gets to the very core of what it means to be human.

The Selfish Gene

Author : Richard Dawkins
Publisher : Oxford University Press, USA
ISBN 13 : 9780192860927
Total Pages : 372 pages
Book Rating : 4.8/5 (69 download)

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Book Synopsis The Selfish Gene by : Richard Dawkins

Download or read book The Selfish Gene written by Richard Dawkins and published by Oxford University Press, USA. This book was released on 1989 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Science need not be dull and bogged down by jargon, as Richard Dawkins proves in this entertaining look at evolution. The themes he takes up are the concepts of altruistic and selfish behaviour; the genetical definition of selfish interest; the evolution of aggressive behaviour; kinshiptheory; sex ratio theory; reciprocal altruism; deceit; and the natural selection of sex differences. 'Should be read, can be read by almost anyone. It describes with great skill a new face of the theory of evolution.' W.D. Hamilton, Science

The Ascent of Information

Author : Caleb Scharf
Publisher : Penguin
ISBN 13 : 0593087259
Total Pages : 353 pages
Book Rating : 4.5/5 (93 download)

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Book Synopsis The Ascent of Information by : Caleb Scharf

Download or read book The Ascent of Information written by Caleb Scharf and published by Penguin. This book was released on 2022-06-14 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Full of fascinating insights drawn from an impressive range of disciplines, The Ascent of Information casts the familiar and the foreign in a dramatic new light.” —Brian Greene, author of The Elegant Universe Your information has a life of its own, and it’s using you to get what it wants. One of the most peculiar and possibly unique features of humans is the vast amount of information we carry outside our biological selves. But in our rush to build the infrastructure for the 20 quintillion bits we create every day, we’ve failed to ask exactly why we’re expending ever-increasing amounts of energy, resources, and human effort to maintain all this data. Drawing on deep ideas and frontier thinking in evolutionary biology, computer science, information theory, and astrobiology, Caleb Scharf argues that information is, in a very real sense, alive. All the data we create—all of our emails, tweets, selfies, A.I.-generated text and funny cat videos—amounts to an aggregate lifeform. It has goals and needs. It can control our behavior and influence our well-being. And it’s an organism that has evolved right alongside us. This symbiotic relationship with information offers a startling new lens for looking at the world. Data isn’t just something we produce; it’s the reason we exist. This powerful idea has the potential to upend the way we think about our technology, our role as humans, and the fundamental nature of life. The Ascent of Information offers a humbling vision of a universe built of and for information. Scharf explores how our relationship with data will affect our ongoing evolution as a species. Understanding this relationship will be crucial to preventing our data from becoming more of a burden than an asset, and to preserving the possibility of a human future.

Enjoy Your Cells

Author : Frances R. Balkwill
Publisher : CSHL Press
ISBN 13 : 9780879695842
Total Pages : 36 pages
Book Rating : 4.6/5 (958 download)

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Book Synopsis Enjoy Your Cells by : Frances R. Balkwill

Download or read book Enjoy Your Cells written by Frances R. Balkwill and published by CSHL Press. This book was released on 2001-10-25 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt: Enjoy Your Cells is a new series of children's books from the acclaimed creative partnership of scientist/author Fran Balkwill and illustrator Mic Rolph. The titles in the series include: Enjoy Your Cells Germ Zappers Have a Nice DNA! Gene Machines Once again, they use their unique brand of simple but scientifically accurate commentary and exuberantly colorful graphics to take young readers on an entertaining exploration of the amazing, hidden world of cells, proteins, and DNA. It's over ten years since Fran and Mic invented a new way of getting science across to children. Think what extraordinary advances have been made in biology in that time - and how often those discoveries made headlines. Stem cells, cloning, embryo transfer, emerging infections, vaccine development...here in these books are the basic facts behind the public debates. With these books, children will learn to enjoy their cells and current affairs at the same time. And they're getting information that has been written and reviewed by working scientists, so it's completely correct and up-to-date. Readers aged 7 and up will appreciate the stories' lively language and with help, even younger children will enjoy and learn from the jokes and illustrations - no expert required! This series is a must for all elementary school students and those who care about educating them to be well-informed in a world of increasingly complex health-related and environmental issues. Fran Balkwill is Professor of Cancer Biology at St. Bartholomew's Hospital and the London Queen Mary School of Medicine. Mic Rolph is a graphic designer with much television and publishing experience. Together, they have created many books for children, and have won several awards, including the prestigious COPUS Junior Science Book Prize.

Smarter Than Their Machines

Author : John Cullinane
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1627055525
Total Pages : 381 pages
Book Rating : 4.6/5 (27 download)

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Book Synopsis Smarter Than Their Machines by : John Cullinane

Download or read book Smarter Than Their Machines written by John Cullinane and published by Morgan & Claypool Publishers. This book was released on 2014-11-01 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: Smarter Than Their Machines: Oral Histories of the Pioneers of Interactive Computing is based on oral histories archived at the Charles Babbage Institute, University of Minnesota. Included are the oral histories of some key pioneers of the computer industry selected by John that led to interactive computing, such as Richard Bloch, Gene Amdahl, Herbert W. Robinson, Sam Wyly, J.C.R. Licklider, Ivan Sutherland, Larry Roberts, Robert Kahn, Marvin Minsky, Michael Dertouzos, and Joseph Traub, as well as his own. John has woven them together via introductions that is, in essence, a personal walk down the computer industry road. John had the unique advantage of having been part of, or witness to, much of the history contained in these oral histories beginning as a co-op student at Arthur D. Little, Inc., in the 1950’s. Eventually, he would become a pioneer in his own right by creating the computer industry's first successful software products company (Cullinane Corporation). However, an added benefit of reading these oral histories is that they contain important messages for our leaders of today, at all levels, including that government, industry, and academia can accomplish great things when working together in an effective way. This is how the computer industry was created, which then led to the Internet, both totally unanticipated just 75 years ago.

The Society of Genes

Author : Itai Yanai
Publisher : Harvard University Press
ISBN 13 : 0674425022
Total Pages : 295 pages
Book Rating : 4.6/5 (744 download)

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Book Synopsis The Society of Genes by : Itai Yanai

Download or read book The Society of Genes written by Itai Yanai and published by Harvard University Press. This book was released on 2016-01-11 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nearly four decades ago Richard Dawkins published The Selfish Gene, famously reducing humans to “survival machines” whose sole purpose was to preserve “the selfish molecules known as genes.” How these selfish genes work together to construct the organism, however, remained a mystery. Standing atop a wealth of new research, The Society of Genes now provides a vision of how genes cooperate and compete in the struggle for life. Pioneers in the nascent field of systems biology, Itai Yanai and Martin Lercher present a compelling new framework to understand how the human genome evolved and why understanding the interactions among our genes shifts the basic paradigm of modern biology. Contrary to what Dawkins’s popular metaphor seems to imply, the genome is not made of individual genes that focus solely on their own survival. Instead, our genomes comprise a society of genes which, like human societies, is composed of members that form alliances and rivalries. In language accessible to lay readers, The Society of Genes uncovers genetic strategies of cooperation and competition at biological scales ranging from individual cells to entire species. It captures the way the genome works in cancer cells and Neanderthals, in sexual reproduction and the origin of life, always underscoring one critical point: that only by putting the interactions among genes at center stage can we appreciate the logic of life.

Evolutionary Approach to Machine Learning and Deep Neural Networks

Author : Hitoshi Iba
Publisher : Springer
ISBN 13 : 9811302006
Total Pages : 254 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Evolutionary Approach to Machine Learning and Deep Neural Networks by : Hitoshi Iba

Download or read book Evolutionary Approach to Machine Learning and Deep Neural Networks written by Hitoshi Iba and published by Springer. This book was released on 2018-06-15 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides theoretical and practical knowledge about a methodology for evolutionary algorithm-based search strategy with the integration of several machine learning and deep learning techniques. These include convolutional neural networks, Gröbner bases, relevance vector machines, transfer learning, bagging and boosting methods, clustering techniques (affinity propagation), and belief networks, among others. The development of such tools contributes to better optimizing methodologies. Beginning with the essentials of evolutionary algorithms and covering interdisciplinary research topics, the contents of this book are valuable for different classes of readers: novice, intermediate, and also expert readers from related fields. Following the chapters on introduction and basic methods, Chapter 3 details a new research direction, i.e., neuro-evolution, an evolutionary method for the generation of deep neural networks, and also describes how evolutionary methods are extended in combination with machine learning techniques. Chapter 4 includes novel methods such as particle swarm optimization based on affinity propagation (PSOAP), and transfer learning for differential evolution (TRADE), another machine learning approach for extending differential evolution. The last chapter is dedicated to the state of the art in gene regulatory network (GRN) research as one of the most interesting and active research fields. The author describes an evolving reaction network, which expands the neuro-evolution methodology to produce a type of genetic network suitable for biochemical systems and has succeeded in designing genetic circuits in synthetic biology. The author also presents real-world GRN application to several artificial intelligent tasks, proposing a framework of motion generation by GRNs (MONGERN), which evolves GRNs to operate a real humanoid robot.

The Meme Machine

Author : Susan Blackmore
Publisher : OUP Oxford
ISBN 13 : 0191574619
Total Pages : 288 pages
Book Rating : 4.1/5 (915 download)

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Book Synopsis The Meme Machine by : Susan Blackmore

Download or read book The Meme Machine written by Susan Blackmore and published by OUP Oxford. This book was released on 2000-03-16 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Humans are extraordinary creatures, with the unique ability among animals to imitate and so copy from one another ideas, habits, skills, behaviours, inventions, songs, and stories. These are all memes, a term first coined by Richard Dawkins in 1976 in his book The Selfish Gene. Memes, like genes, are replicators, and this enthralling book is an investigation of whether this link between genes and memes can lead to important discoveries about the nature of the inner self. Confronting the deepest questions about our inner selves, with all our emotions, memories, beliefs, and decisions, Susan Blackmore makes a compelling case for the theory that the inner self is merely an illusion created by the memes for the sake of replication.

Murder Machine

Author : Gene Mustain
Publisher : Penguin
ISBN 13 : 1101665882
Total Pages : 496 pages
Book Rating : 4.1/5 (16 download)

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Book Synopsis Murder Machine by : Gene Mustain

Download or read book Murder Machine written by Gene Mustain and published by Penguin. This book was released on 1993-07-01 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The inside story of a single Brooklyn gang that killed more Americans than the Iraqi army."—Mike McAlary, columnist, New York Post They were the DeMeo gang—the most deadly hit men in organized crime. Their Mafia higher-ups came to know, use, and ultimately fear them as the Murder Machine. They killed for profit and for pleasure, following cold-blooded plans and wild whims, from the mean streets of New York to the Florida Gold Coast, and from coast to coast. Now complete with personal revelations of one of the key players, this is the savage story that leaves no corpse unturned in its terrifying telling. INCLUDES PHOTOGRAPHS

Evolvable Machines

Author : Nadia Nedjah
Publisher : Springer
ISBN 13 : 3540323643
Total Pages : 276 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Evolvable Machines by : Nadia Nedjah

Download or read book Evolvable Machines written by Nadia Nedjah and published by Springer. This book was released on 2006-06-23 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods for the artificial evolution of active components, such as programs and hardware, are rapidly developing branches of adaptive computation and adaptive engineering. Evolvable Machines reports innovative and significant progress in automatic and evolutionary methodology applied to machine design. This book presents theoretical as well as practical chapters concentrating on Evolvable Robots, Evolvable Hardware Synthesis, as well as Evolvable Design.

Gene Regulation and Metabolism

Author : Julio Collado-Vides
Publisher : MIT Press
ISBN 13 : 9780262532686
Total Pages : 326 pages
Book Rating : 4.5/5 (326 download)

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Book Synopsis Gene Regulation and Metabolism by : Julio Collado-Vides

Download or read book Gene Regulation and Metabolism written by Julio Collado-Vides and published by MIT Press. This book was released on 2002 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of current computational approaches to metabolism and gene regulation.

Computational Genomics with R

Author : Altuna Akalin
Publisher : CRC Press
ISBN 13 : 1498781861
Total Pages : 463 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Computational Genomics with R by : Altuna Akalin

Download or read book Computational Genomics with R written by Altuna Akalin and published by CRC Press. This book was released on 2020-12-16 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Genomics with R provides a starting point for beginners in genomic data analysis and also guides more advanced practitioners to sophisticated data analysis techniques in genomics. The book covers topics from R programming, to machine learning and statistics, to the latest genomic data analysis techniques. The text provides accessible information and explanations, always with the genomics context in the background. This also contains practical and well-documented examples in R so readers can analyze their data by simply reusing the code presented. As the field of computational genomics is interdisciplinary, it requires different starting points for people with different backgrounds. For example, a biologist might skip sections on basic genome biology and start with R programming, whereas a computer scientist might want to start with genome biology. After reading: You will have the basics of R and be able to dive right into specialized uses of R for computational genomics such as using Bioconductor packages. You will be familiar with statistics, supervised and unsupervised learning techniques that are important in data modeling, and exploratory analysis of high-dimensional data. You will understand genomic intervals and operations on them that are used for tasks such as aligned read counting and genomic feature annotation. You will know the basics of processing and quality checking high-throughput sequencing data. You will be able to do sequence analysis, such as calculating GC content for parts of a genome or finding transcription factor binding sites. You will know about visualization techniques used in genomics, such as heatmaps, meta-gene plots, and genomic track visualization. You will be familiar with analysis of different high-throughput sequencing data sets, such as RNA-seq, ChIP-seq, and BS-seq. You will know basic techniques for integrating and interpreting multi-omics datasets. Altuna Akalin is a group leader and head of the Bioinformatics and Omics Data Science Platform at the Berlin Institute of Medical Systems Biology, Max Delbrück Center, Berlin. He has been developing computational methods for analyzing and integrating large-scale genomics data sets since 2002. He has published an extensive body of work in this area. The framework for this book grew out of the yearly computational genomics courses he has been organizing and teaching since 2015.

The Truth Machines

Author : Jinee Lokaneeta
Publisher : University of Michigan Press
ISBN 13 : 0472054392
Total Pages : 263 pages
Book Rating : 4.4/5 (72 download)

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Book Synopsis The Truth Machines by : Jinee Lokaneeta

Download or read book The Truth Machines written by Jinee Lokaneeta and published by University of Michigan Press. This book was released on 2020-02-26 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using case studies and the results of extensive fieldwork, this book considers the nature of state power and legal violence in liberal democracies by focusing on the interaction between law, science, and policing in India. The postcolonial Indian police have often been accused of using torture in both routine and exceptional criminal cases, but they, and forensic psychologists, have claimed that lie detectors, brain scans, and narcoanalysis (the use of “truth serum,” Sodium Pentothal) represent a paradigm shift away from physical torture; most state high courts in India have upheld this rationale. The Truth Machines examines the emergence and use of these three scientific techniques to analyze two primary themes. First, the book questions whether existing theoretical frameworks for understanding state power and legal violence are adequate to explain constant innovations of the state. Second, it explores the workings of law, science, and policing in the everyday context to generate a theory of state power and legal violence, challenging the monolithic frameworks about this relationship, based on a study of both state and non-state actors. Jinee Lokaneeta argues that the attempt to replace physical torture with truth machines in India fails because it relies on a confessional paradigm that is contiguous with torture. Her work also provides insights into a police institution that is founded and refounded in its everyday interactions between state and non-state actors. Theorizing a concept of Contingent State, this book demonstrates the disaggregated, and decentered nature of state power and legal violence, creating possible sites of critique and intervention.

The Selfish Gene

Author : Richard Dawkins
Publisher : Oxford University Press
ISBN 13 : 0191093068
Total Pages : 497 pages
Book Rating : 4.1/5 (91 download)

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Book Synopsis The Selfish Gene by : Richard Dawkins

Download or read book The Selfish Gene written by Richard Dawkins and published by Oxford University Press. This book was released on 2016-05-26 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: The million copy international bestseller, critically acclaimed and translated into over 25 languages. As influential today as when it was first published, The Selfish Gene has become a classic exposition of evolutionary thought. Professor Dawkins articulates a gene's eye view of evolution - a view giving centre stage to these persistent units of information, and in which organisms can be seen as vehicles for their replication. This imaginative, powerful, and stylistically brilliant work not only brought the insights of Neo-Darwinism to a wide audience, but galvanized the biology community, generating much debate and stimulating whole new areas of research. Forty years later, its insights remain as relevant today as on the day it was published. This 40th anniversary edition includes a new epilogue from the author discussing the continuing relevance of these ideas in evolutionary biology today, as well as the original prefaces and foreword, and extracts from early reviews. Oxford Landmark Science books are 'must-read' classics of modern science writing which have crystallized big ideas, and shaped the way we think.