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Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Graeme L Hammond
Publisher : World Scientific
ISBN 13 : 9814492604
Total Pages : 328 pages
Book Rating : 4.8/5 (144 download)
Download or read book Gene Families: Studies Of Dna, Rna, Enzymes & Proteins written by Graeme L Hammond and published by World Scientific. This book was released on 2001-06-22 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: This archival volume is an invaluable collection of rigorously reviewed articles by experts in the fields of gene families, DNA, RNA and proteins, to commemorate the passing of a giant of science — Professor Clement L Markert (1917-1999).In 1959, Clement Markert and Freddy Moller developed the concept of the isozyme, which paved the way for extensive studies of enzyme, protein and gene multiplicity across all living organisms. This important scientific discovery has had a profound influence on the biological sciences for more than 40 years, and has provided the basis for regular international meetings to discuss the biological and biomedical implications of enzyme multiplicity. More recently, this concept has been extended to a wide range of gene families of DNA, RNA, proteins and enzymes.
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309038405
Total Pages : 128 pages
Book Rating : 4.3/5 (9 download)
Download or read book Mapping and Sequencing the Human Genome written by National Research Council and published by National Academies Press. This book was released on 1988-01-01 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.
Author : James D. Watson
Publisher : Knopf
ISBN 13 : 0307521486
Total Pages : 464 pages
Book Rating : 4.3/5 (75 download)
Download or read book DNA written by James D. Watson and published by Knopf. This book was released on 2009-01-21 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fifty years ago, James D. Watson, then just twentyfour, helped launch the greatest ongoing scientific quest of our time. Now, with unique authority and sweeping vision, he gives us the first full account of the genetic revolution—from Mendel’s garden to the double helix to the sequencing of the human genome and beyond. Watson’s lively, panoramic narrative begins with the fanciful speculations of the ancients as to why “like begets like” before skipping ahead to 1866, when an Austrian monk named Gregor Mendel first deduced the basic laws of inheritance. But genetics as we recognize it today—with its capacity, both thrilling and sobering, to manipulate the very essence of living things—came into being only with the rise of molecular investigations culminating in the breakthrough discovery of the structure of DNA, for which Watson shared a Nobel prize in 1962. In the DNA molecule’s graceful curves was the key to a whole new science. Having shown that the secret of life is chemical, modern genetics has set mankind off on a journey unimaginable just a few decades ago. Watson provides the general reader with clear explanations of molecular processes and emerging technologies. He shows us how DNA continues to alter our understanding of human origins, and of our identities as groups and as individuals. And with the insight of one who has remained close to every advance in research since the double helix, he reveals how genetics has unleashed a wealth of possibilities to alter the human condition—from genetically modified foods to genetically modified babies—and transformed itself from a domain of pure research into one of big business as well. It is a sometimes topsy-turvy world full of great minds and great egos, driven by ambitions to improve the human condition as well as to improve investment portfolios, a world vividly captured in these pages. Facing a future of choices and social and ethical implications of which we dare not remain uninformed, we could have no better guide than James Watson, who leads us with the same bravura storytelling that made The Double Helix one of the most successful books on science ever published. Infused with a scientist’s awe at nature’s marvels and a humanist’s profound sympathies, DNA is destined to become the classic telling of the defining scientific saga of our age.
Author : Paul D. Waters
Publisher : Springer Science & Business Media
ISBN 13 : 9048190231
Total Pages : 518 pages
Book Rating : 4.0/5 (481 download)
Download or read book Marsupial Genetics and Genomics written by Paul D. Waters and published by Springer Science & Business Media. This book was released on 2010-08-05 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: Marsupials belong to the Class Mammalia, sharing some features with other mammals, yet they also possess many unique features. It is their differences from the more traditionally studied mammals, such as mice and humans, that is of greatest value to comparative studies. Sequencing of genomes from two distantly related marsupials, the short grey-tailed opossum from South America and the Australian tammar wallaby, has launched marsupials into the genomics era and accelerated the rate of progress in marsupial research. With the current worldwide concern for the plight of the endangered Tasmanian devil, marsupial genetics and genomics research is even more important than ever if this species is to be saved from extinction. This volume recounts some of the history of research in this field and highlights the most recent advances in the many different areas of marsupial genetics and genomics research.
Author : Anne C. Ferguson-Smith
Publisher : Springer Science & Business Media
ISBN 13 : 1402091877
Total Pages : 437 pages
Book Rating : 4.4/5 (2 download)
Download or read book Epigenomics written by Anne C. Ferguson-Smith and published by Springer Science & Business Media. This book was released on 2008-12-05 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetic modifications act on DNA and its packaging proteins, the histones, to regulate genome function. Manifest as the heritable methylation of DNA and as post-translational histone modifications, these molecular flags influence the architecture and integrity of the chromosome, the accessibility of DNA to gene regulatory components and the ability of chromatin to interact within nuclear complexes. While a multicellular individual has only one genome, it has multiple epigenomes reflecting the diversity of cell types and their properties at different times of life; in health and in disease. Relationships are emerging between the underlying DNA sequence and dynamic epigenetic states and their consequences,such as the role of RNA interference and non-coding RNA. These integrated approaches go hand-in-hand with studies describing the genomic locations of epigenetic modifications in different cell types at different times. The excitement and curiosity surrounding epigenomics is driven by a growing community of researchers in a burgeoning field and the development of new technologies built on the backbone of genome sequencing projects. Research has shown that the adaptability and vulnerability of epigenetic states has profound effects on natural variation, the response of the genome to its environment and on health and disease. The aim of this volume is not to describe epigenomes, but rather to explore how understanding epigenomes tells us more about how biological systems work and the challenges and approaches taken to accomplish this. These contributions have attempted to integrate epigenomics into our understanding of genomes in wider context, and to communicate some of the wonders of epigenetics illustrated through examples across the biological spectrum.
Author : L. Joseph Su
Publisher : Springer
ISBN 13 : 1447166787
Total Pages : 327 pages
Book Rating : 4.4/5 (471 download)
Download or read book Environmental Epigenetics written by L. Joseph Su and published by Springer. This book was released on 2015-05-18 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.
Author : Hwa A Lim
Publisher : World Scientific
ISBN 13 : 9814477567
Total Pages : 444 pages
Book Rating : 4.8/5 (144 download)
Download or read book Multiplicity Yours: Cloning, Stem Cell Research, And Regenerative Medicine written by Hwa A Lim and published by World Scientific. This book was released on 2006-07-21 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book of its kind that treats reproduction, cloning, stem cell research and regenerative medicine in an integrative manner.Touching on the science, social aspects, legal and ethical issues, and the current status of cloning, stem cell research and regenerative medicine, this self-contained book is an excellent source for introducing newcomers to the field or broadening the perspectives of experts and practitioners.In contrast to existing books on the market, which treat each topic in isolation or sensationalize the areas, this book takes an integrative and balanced approach. The treatment is easy to grasp and clear illustrations, graphics and photos explain the key concepts. The book explains the diverse topics from a scientific angle, a social perspective, and as a natural business development. The coverage also includes the political and ethical issues as well as many other thought-provoking scenarios.
Author : Hwa A. Lim
Publisher : World Scientific
ISBN 13 : 981024939X
Total Pages : 440 pages
Book Rating : 4.8/5 (12 download)
Download or read book Genetically Yours written by Hwa A. Lim and published by World Scientific. This book was released on 2002 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers all the key aspects and current affairs in the field of biotechnology, with topics ranging from genome projects, through animal and human cloning, to biowarfare.
Author : Maria Spies
Publisher : Springer Science & Business Media
ISBN 13 : 1461450373
Total Pages : 308 pages
Book Rating : 4.4/5 (614 download)
Download or read book DNA Helicases and DNA Motor Proteins written by Maria Spies and published by Springer Science & Business Media. This book was released on 2012-11-19 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, a number of groundbreaking structural and mechanistic studies deepened our understanding of helicase mechanisms and established new approaches for their analyses. Many fundamental mechanistic questions ranging from the mechanism of force generation, mechanochemical coupling to distinct mechanisms by which the same enzyme translocates on DNA removing obstacles, unwinds DNA and/or remodels nucleoprotein complexes, however, remain to be answered. It is even less understood how the helicase motors are incorporated into a wide range of genome maintenance and repair machines. The field has reached a stage when the studies of molecular mechanisms and basic biology of helicases can and shall be integrated with the studies of development, cancer and longevity. The objective of this book is to provide the first systematic overview of structure, function and regulation of DNA helicases and related molecular motors. By integrating the knowledge obtained through the diverse technical approaches ranging from single-molecule biophysics to cellular and molecular biological studies the editors aim to provide a unified view on how helicases function in the cell, are regulated in response to different cellular stresses and are integrated into large macromolecular assemblies to form a complex and adaptive living system.
Author : Claudiu T. Supuran
Publisher : CRC Press
ISBN 13 : 1134400152
Total Pages : 560 pages
Book Rating : 4.1/5 (344 download)
Download or read book Carbonic Anhydrase written by Claudiu T. Supuran and published by CRC Press. This book was released on 2004-05-27 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbonic Anhydrase: Its Inhibitors and Activators provides a state-of-the-art overview of the latest developments and challenges in carbonic anhydrase research. Authors describe the mechanisms of action of specific inhibitors in relation to physiological function, and present previously unpublished research on CA activators. Written by a team of in
Author : Solomon P. Wasser
Publisher : Springer Science & Business Media
ISBN 13 : 9401704430
Total Pages : 483 pages
Book Rating : 4.4/5 (17 download)
Download or read book Evolutionary Theory and Processes: Modern Horizons written by Solomon P. Wasser and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents provocative research in four broad areas: Evolution of Life and Evolutionary Theory, including papers on the origin of life, stress and evolution; Genome Evolution, including papers on adaptive genome regulation, and comparative mammalian genomes; Phylogeography and Phylogeny, including papers on mushroom phylogeny, macroevolution, and the origin of higher taxa; Human Evolution and Ecology, including papers on man's place in nature, and the origin of human hairlessness.
Author : Eviatar Nevo
Publisher : Springer Science & Business Media
ISBN 13 : 9781402016936
Total Pages : 500 pages
Book Rating : 4.0/5 (169 download)
Download or read book Evolutionary Theory and Processes: Modern Horizons written by Eviatar Nevo and published by Springer Science & Business Media. This book was released on 2004-01-31 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evolution is the most profound of human ideas integrating all natural phenomena: cosmic, biological, and cultural into a continuous universal change. This volume deals with evolutionary observations, experiments, and theories contributing to a deeper understanding of the evolutionary process, th honoring the 75 birthday of Eviatar (Eibi) Nevo. I first met Eibi in 1966 when he was a Fellow in the Museum of Comparative Zoology at Harvard University and working mostly on cricket frog vocalization and speciation in the United States. His unique discovery of pipid fossil frogs in the Israeli Early Cretaceous, central Negev, is possibly the largest world collection of ancient fossil frogs. Our acquaintance developed into mutual friendship and admiration. Since then our long-lasting friendship has included a visit to Israel, enabling me to follow Eibi's major scientific achievements, in particular, his founding of the Institute of Evolution in the University of Haifa and now the pending establishment of the International Graduate School of Evolution. The research program of Eibi Nevo, in collaboration with numerous colleagues and students in Israel and across the world, encompasses diverse perspectives of evolutionary biology and biodiversity of genes, populations, species, and ecosystems integrating modem and classical evolutionary approaches, molecular and organismal. They deal with model organisms in all forms from bacteria through plants, fungi, animals, and humans conducted over local, regional, and global scales.
Author : Jamie A. Goode
Publisher : John Wiley & Sons
ISBN 13 : 9780471499596
Total Pages : 322 pages
Book Rating : 4.4/5 (995 download)
Download or read book The Tumour Microenvironment written by Jamie A. Goode and published by John Wiley & Sons. This book was released on 2001-11-28 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Several fundamentally important questions form the basis for this book. What are the relationships between tumour formation and tumour pH? What are the effects of tumour pH and hypoxia on carcinogenesis or tumorigenesis? What are the therapeutic consequences of tumour pH? It is hypothesised that low extracellular pH is not only an important consequence of tumour growth but may also promote further tumorigenic transformation. Furthermore, in vitro studies suggest that low pH strongly affects the efficacy of chemo- and radiotherapy. Better understanding of the influence of pH on tumour growth, coupled with manipulation of the pH of the tumour microenvironment, may lead to the development of more effective therapies.
Author : Jules Janick
Publisher : John Wiley & Sons
ISBN 13 : 0470171529
Total Pages : 493 pages
Book Rating : 4.4/5 (71 download)
Download or read book Plant Breeding Reviews written by Jules Janick and published by John Wiley & Sons. This book was released on 2008-01-14 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant Breeding Reviews presents state-of-the-art reviews on plant breeding and genetics covering horticultural, agronomic and forestry crops, incorporating both traditional and molecular methods. The contributions are authored by world authorities, anonymously reviewed, and edited by Professor Jules Janick of Perdue University, USA. The series is an indispensible resource for crop breeders, plant scientists, and teachers involved in crop improvement and genetic resources. Initiated in 1983, Plant Breeding Reviews is published in the form of one or two volumes per year. Recently published articles include: Epigenetics and Plant Breeding (v30) Enhancing Crop Gene Pools with Beneficial Traits Using Wild Relatives (v30) Coffee Germplasm Resources, Genomics and Breeding (v30) Molecular Genetics and Breeding for Fatty Acid Manipulation in Soybean (v30) Breeding Southern Highbush Blueberries (v30) Development of Fire Blight Resistance by Recombinant DNA Technology (v29)
Author : Abram Bent︠s︡ionovich Korolʹ
Publisher : Margulis Michael
ISBN 13 : 9655554015
Total Pages : 220 pages
Book Rating : 4.6/5 (555 download)
Download or read book The Evolution of Eibi Nevo written by Abram Bent︠s︡ionovich Korolʹ and published by Margulis Michael. This book was released on 2009 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kazuhiko Nakatani
Publisher : Springer
ISBN 13 : 3319271113
Total Pages : 280 pages
Book Rating : 4.3/5 (192 download)
Download or read book Modified Nucleic Acids written by Kazuhiko Nakatani and published by Springer. This book was released on 2016-04-04 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book spans diverse aspects of modified nucleic acids, from chemical synthesis and spectroscopy to in vivo applications, and highlights studies on chemical modifications of the backbone and nucleobases. Topics discussed include fluorescent pyrimidine and purine analogs, enzymatic approaches to the preparation of modified nucleic acids, emission and electron paramagnetic resonance (EPR) spectroscopy for studying nucleic acid structure and dynamics, non-covalent binding of low- and high-MW ligands to nucleic acids and the design of unnatural base pairs. This unique book addresses new developments and is designed for graduate level and professional research purposes.
