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Gendering The Genome
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Download or read book Sex Itself written by Sarah S. Richardson and published by University of Chicago Press. This book was released on 2013-12-13 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human genomes are 99.9 percent identical—with one prominent exception. Instead of a matching pair of X chromosomes, men carry a single X, coupled with a tiny chromosome called the Y. Tracking the emergence of a new and distinctive way of thinking about sex represented by the unalterable, simple, and visually compelling binary of the X and Y chromosomes, Sex Itself examines the interaction between cultural gender norms and genetic theories of sex from the beginning of the twentieth century to the present, postgenomic age. Using methods from history, philosophy, and gender studies of science, Sarah S. Richardson uncovers how gender has helped to shape the research practices, questions asked, theories and models, and descriptive language used in sex chromosome research. From the earliest theories of chromosomal sex determination, to the mid-century hypothesis of the aggressive XYY supermale, to the debate about Y chromosome degeneration, to the recent claim that male and female genomes are more different than those of humans and chimpanzees, Richardson shows how cultural gender conceptions influence the genetic science of sex. Richardson shows how sexual science of the past continues to resonate, in ways both subtle and explicit, in contemporary research on the genetics of sex and gender. With the completion of the Human Genome Project, genes and chromosomes are moving to the center of the biology of sex. Sex Itself offers a compelling argument for the importance of ongoing critical dialogue on how cultural conceptions of gender operate within the science of sex.
Book Synopsis Exploring the Biological Contributions to Human Health by : Institute of Medicine
Download or read book Exploring the Biological Contributions to Human Health written by Institute of Medicine and published by National Academies Press. This book was released on 2001-07-02 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.
Book Synopsis Principles of Gender-Specific Medicine by : Marianne Legato J
Download or read book Principles of Gender-Specific Medicine written by Marianne Legato J and published by Academic Press. This book was released on 2017-05-15 with total page 794 pages. Available in PDF, EPUB and Kindle. Book excerpt: The announcement that we had decoded the human genome in 2000 ushered in a new and unique era in biomedical research and clinical medicine. This Third Edition of Principles of Gender-Specific Medicine focuses, as in the past two editions, on the essentials of sexual dimorphism in human physiology and pathophysiology, but emphasizes the latest information about molecular biology and genomic science in a variety of disciplines. Thus, this edition is a departure from the previous two; the editor solicited individual manuscripts from innovative scientists in a variety of fields rather than the traditional arrangement of sections devoted to the various subspecialties of medicine edited by section chiefs. Wherever it was available, these authors incorporated the latest information about the impact of the genome and the elements that modify its expression on human physiology and illness. All chapters progress translationally from basic science to the clinical applications of gender-specific therapy and suggest the most important topics for future investigation. This book is essential reading for all biomedical investigators and medical educators involved in gender-specific medicine. It will also be useful for primary care practitioners who need information about the importance of sex and gender in the prevention, diagnosis and treatment of illness. Winner of the 2018 PROSE Award in Clinical Medicine from the Association of American Publishers! 2018 PROSE Awards - Winner, Award for Clinical Medicine: Association of American Publishers Outlines sex-specific differences in normal human function and explains the impact of age, hormones, and environment on the incidence and outcome of illness Reflects the latest information about the molecular basis of the sexual dimorphism in human physiology and the experience of disease Reviews the implications of our ever-improving ability to describe the genetic basis of vulnerability to disease and our capacity to alter the genome itself Illustrates the importance of new NIH guidelines that urge the inclusion of sex as a variable in research protocols
Book Synopsis Gendering the Genome by : Sarah S. Richardson
Download or read book Gendering the Genome written by Sarah S. Richardson and published by . This book was released on 2009 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Gender and Genes by : Klasien Horstman
Download or read book Gender and Genes written by Klasien Horstman and published by Uitgeverij Verloren. This book was released on 2013 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Yearbook of Women's History (Jaarboek voor Vrouwengeschiedenis) is dedicated to Gender and Genes. Intruding upon our everyday lives, the world of DNA, genes and genomics has become a challenging field of research, both clinical and biomedical as well as socio-cultural. It is also a challenging topic for a Yearbook which traditionally focuses on women and gender from a historical point of view. Gender issues are part and parcel of genes and genomics in scientific research and socio-cultural discourses and representations. Current literature on genes and genomics does not abound in analyses of biomedical and socio-cultural realms where gender aspects are played out and exchanged. This Yearbookmay thus contribute to a field of analysis which contextualizes history from the viewpoint of current biotechnological developments. This volume contains articles on medical cases (reproductive testing and the case of the sex chromosomes, and framing cancer risk in women and men), cultural representations, a portrait of female scientist Rosalin Franklin and interviews with feminist science philosophers Katarina Karkazis and Donna Dickenson.
Book Synopsis The Material Gene by : Kelly E. Happe
Download or read book The Material Gene written by Kelly E. Happe and published by NYU Press. This book was released on 2013-05-06 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: Winner of the 2014 Diamond Anniversary Book Award Finalist for the 2014 National Communications Association Critical and Cultural Studies Division Book of the Year Award In 2000, the National Human Genome Research Institute announced the completion of a “draft” of the human genome, the sequence information of nearly all 3 billion base pairs of DNA. Since then, interest in the hereditary basis of disease has increased considerably. In The Material Gene, Kelly E. Happe considers the broad implications of this development by treating “heredity” as both a scientific and political concept. Beginning with the argument that eugenics was an ideological project that recast the problems of industrialization as pathologies of gender, race, and class, the book traces the legacy of this ideology in contemporary practices of genomics. Delving into the discrete and often obscure epistemologies and discursive practices of genomic scientists, Happe maps the ways in which the hereditarian body, one that is also normatively gendered and racialized, is the new site whereby economic injustice, environmental pollution, racism, and sexism are implicitly reinterpreted as pathologies of genes and by extension, the bodies they inhabit. Comparing genomic approaches to medicine and public health with discourses of epidemiology, social movements, and humanistic theories of the body and society, The Material Gene reworks our common assumption of what might count as effective, just, and socially transformative notions of health and disease.
Book Synopsis The Material Gene by : Kelly E. Happe
Download or read book The Material Gene written by Kelly E. Happe and published by NYU Press. This book was released on 2013-05-06 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 2000, the National Human Genome Research Institute announced the completion of a “draft” of the human genome, the sequence information of nearly all 3 billion base pairs of DNA. In the wake of this major scientific accomplishment, the focus on the genetic basis of disease has sparked many controversies as questions are raised about radical preventative therapies, the role of race in research, and the environmental origins of illness. In The Material Gene, Kelly Happe explores the cultural and social dimensions of our understandings of genomics, using this emerging field to examine the physical manifestation of social relations. Situating contemporary genomics medicine and public health within a wider history of eugenics, Happe examines how the relationship between heredity and dominant social and economic interests has shifted along with transformations in gender and racial politics, social movement, and political economy. Happe demonstrates that genomics is a type of social knowledge, relying on cultural values to attach meaning to the body. The Material Gene situates contemporary genomics within a history of genetics research yet is attentive to the new ways in which knowledge claims about heredity, race, and gender emerge and are articulated to present-day social and political agendas. Kelly E. Happe is assistant professor of communication studies and women’s studies at the University of Georgia.
Book Synopsis Im/partial Science by : Bonnie Spanier
Download or read book Im/partial Science written by Bonnie Spanier and published by Indiana University Press. This book was released on 1995 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Best known today for her nature writing and southwestern cultural studies, Mary Hunter Austin (1868-1934) has been increasingly recognized for her outspoken essays on feminist themes. This volume collects her nonfiction journalism, with each essay prefaced by brief introductory remarks by the editor. Annotation copyright by Book News, Inc., Portland, OR
Download or read book Gene Worship written by Gisela Kaplan and published by Other Press, LLC. This book was released on 2010-08-10 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: "A wonderful antidote to the gene hysteria that is now so dominant! . . . What is most exciting about this book is the authors' ability to move seamlessly from research on how the brain works, to sociology, history, and philosophy. And that, I believe, is exactly how we need to understand gender--neither nature nor nurture, but a complex interplay." - Dr. Lynda Birke, author of Feminism and the Biological Body This work moves beyond the old nature/nurture debate concerning what makes us who we are to present a new understanding of gender and sexuality. Since the mapping of the human genome there has been widespread coverage of scientific discoveries in the offing, and of the host of human problems to be solved through gene therapy, from physical defects to mental disease and even so-called 'undesirable' behavior. As biologists with expertise in neuroscience, ethology, psychology, sociology and human ethos, Kaplan and Rogers are uniquely situated to evaluate the claims of their colleagues concerning the knowledge to be gained through the study of our biological make-up. They caution against the seductive belief that, once we understand our biological constitution, it is but a short step to complete mastery of human nature. Furthermore, they show that this belief is yet another example of how science can be subverted to defend the claims of the ruling ideology.
Book Synopsis The Plasticity of Sex by : Marianne J. Legato
Download or read book The Plasticity of Sex written by Marianne J. Legato and published by Academic Press. This book was released on 2020-05-19 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Plasticity of Sex: The Molecular Biology and Clinical Features of Genomic Sex, Gender Identity and Sexual Behavior provides a comprehensive view on the development of human sexuality. As there has been a crescendo of interest over the past several decades about the nature and diversity of human sexuality, this reference brings the evidence-based research into one place. The emergence of issues surrounding gender identity, genital ambivalence and the transition from one sex to another is striking, with the public and treating physicians alike clamoring for an evidence-based, comprehensive treatment of human sexuality and all its variations. This is a must-have reference for biomedical researchers in endocrinology, neuroscience, development biology, medical students, residents, and practicing physicians from all medical areas. Winner of the 2021 PROSE Award in Biomedicine from the Association of American Publishers! Discusses the role of biology in gender identity from research in genetics, endocrinology and neuroscience Addresses important health disparities and how to address them when treating the transgender patient Reviews evidence-based information on the biological basis and impact of environmental and hormonal factors at different life stages Outlines schema for treating variations in the sexuality and sexual function of the individual patient
Download or read book DNA written by Linda L. McCabe and published by Univ of California Press. This book was released on 2008-03-04 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: The genetic revolution has provided incredibly valuable information about our DNA, information that can be used to benefit and inform—but also to judge, discriminate, and abuse. An essential reference for living in today's world, this book gives the background information critical to understanding how genetics is now affecting our everyday lives. Written in clear, lively language, it gives a comprehensive view of exciting recent discoveries and explores the ethical, legal, and social issues that have arisen with each new development.
Book Synopsis Principles of Gender-Specific Medicine by : Marianne Legato J
Download or read book Principles of Gender-Specific Medicine written by Marianne Legato J and published by Academic Press. This book was released on 2023-04-03 with total page 932 pages. Available in PDF, EPUB and Kindle. Book excerpt: Awarded with the 2018 Prose Award in Clinical Medicine, the third edition of Principles of Gender-Specific Medicine explored and described exciting new areas in biomedicine that integrated technology into the treatment of disease and the augmentation of human function. Novel topics such as the sex-specific aspects of space medicine, the development and the use of genderized robots and a discussion of cyborgs were included in the third edition, providing a preview of the expanding world of sex-specific physiology and therapeutics. This Fourth Edition is a continuation of the mission to trace the relevance of biological sex to normal function and to the experience of disease in humans.We are now twenty years into the postgenomic era. The investigation of how the genome produces the phenome has led to fascinating insights as well as yet unanswered questions. Principles of Gender-Specific Medicine, Fourth Edition, has a central theme: discuss advances in understanding the role of epigenetics in regulating gene expression in a dynamic, sex-specific way during human life. It explores the protean role of epigenetics in human physiology, the relevance of environmental experience to human function, the therapeutic promise of cutting-edge methodologies like gene manipulation, the preparation of humans for space travel, the use of artificial intelligence in detection and therapeutic decisions concerning disease states, the possibilities for technological support of not only compromised individuals but of the augmentation of human function, and an analysis of the benefits, limitations and issues that surround our current expectations of personalized medicine. Covers the most important developments in biomedical research in the past decade, with a thoughtful analysis of how they impact patient care Discusses the feasibility and usefulness of personalized medicine, the limits and promise of genetic editing, the basis for variation in sexual identity and how artificial intelligence and technology will affect basic human function as well as correcting disability Promotes and facilitates discussions about the ethics and governance issues that surround much of what science is now able to do at the most basic levels of human’s physiology
Book Synopsis Genetics of Human Infertility by : P.H. Vogt
Download or read book Genetics of Human Infertility written by P.H. Vogt and published by Karger Medical and Scientific Publishers. This book was released on 2017-09-12 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infertility affects more than one in ten couples worldwide and is related to highly heterogeneous pathologies sometimes only discernible in the germ line. Its complex etiology often, but not always, includes genetic factors besides anatomical defects, immunological interference, and environmental aspects. Nearly 30% of infertility cases are probably caused only by genetic defects. Thereby experimental animal knockout models convincingly show that infertility can be caused by single or multiple gene defects. Translating those basic research findings into clinical studies is challenging, leaving genetic causes for the vast majority of infertility patients unexplained. Nevertheless, a large number of candidate genes have been revealed by sophisticated molecular methods. This book provides a comprehensive overview on the subject of infertility written by the leading authorities in this field. It covers topics including basic biological, cytological, and molecular studies, as well as common and uncommon syndromes. It is a must-read for human geneticists, endocrinologists, epidemiologists, zoologists, and counsellors in human genetics, infertility, and assisted reproduction.
Book Synopsis Th Material Gene by : Kelly E. Happe
Download or read book Th Material Gene written by Kelly E. Happe and published by . This book was released on 2013 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: "In 2000, the National Human Genome Research Institute announced the completion of a "draft" of the human genome, the sequence information of nearly all 3 billion base pairs of DNA. In the wake of this major scientific accomplishment, the focus on the genetic basis of disease has sparked many controversies as questions are raised about radical preventative therapies, the role of race in research, and the environmental origins of illness. In The Material Gene, Kelly Happe explores the cultural and social dimensions of our understandings of genomics, using this emerging field to examine the physical manifestation of social relations. Situating contemporary genomics medicine and public health within a wider history of eugenics, Happe examines how the relationship between heredity and dominant social and economic interests has shifted along with transformations in gender and racial politics, social movement, and political economy. Happe demonstrates that genomics is a type of social knowledge, relying on cultural values to attach meaning to the body. The Material Gene situates contemporary genomics within a history of genetics research yet is attentive to the new ways in which knowledge claims about heredity, race, and gender emerge and are articulated to present-day social and political agendas. Kelly E. Happe is assistant professor of communication studies and womens studies at the University of Georgia"--.
Book Synopsis Genetics of Sex Determination by : Ram S. Verma
Download or read book Genetics of Sex Determination written by Ram S. Verma and published by Elsevier Science Limited. This book was released on 1996 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Genetical Theory of Natural Selection by R.A. Fisher (1930) dictated that sexual dimorphisms may depend upon a single medelian factor. This could be true for some species but his suggestion could not take off the ground as gender in Drosophila is determined by the number of X chromosomes. Technical advances in molecular biology have revived the initial thinking of Fisher and dictate that TDF or SRY genes in humans or Tdy in mice are sex determining genes. The fortuitous findings of XX males and XY female, which are generally termed sex reversal phenomenon, are quite bewildering traits that have caused much amazement concerning the pairing mechanism(s) of the pseudoautosomal regions of human X and Y chromosomes at meiosis. These findings have opened new avenues to explore further the genetic basis of sex determination at the single gene level. The aim of the fourth volume, titled Genetics of Sex Determination is to reflect on the latest advances and future investigative directions, encompassing 10 chapters. Commissioned several distinguished scientists, all pre-eminent authorities in each field to shed their thoughts concisely but epitomise their chapters with an extended bibliography. Obviously, during the past 60 years, the metoric advances are voluminous and to cover every account of genes, chromosomes, and sex in a single volume format would be a herculean task. Therefore, a few specific topics are chosen, which may be of great interest to scientists and clinicians. The seasoned scientists who love to inquire about the role of genes in sex determination should find the original work of these notable contributors very enlightening. This volume is intended for advanced students who want to keep abreast as well as for those who indulge in the search for genes of sex determination.
Download or read book The X in Sex written by David. BAINBRIDGE and published by Harvard University Press. This book was released on 2009-06-30 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: A tiny scrap of genetic information determines our sex; it also consigns many of us to a life of disease, directs or disrupts the everyday working of our bodies, and forces women to live as genetic chimeras. The culprit--so necessary and yet the source of such upheaval--is the X chromosome, and this is its story. An enlightening and entertaining tour of the cultural and natural history of this intriguing member of the genome, The X in Sex traces the journey toward our current understanding of the nature of X. From its chance discovery in the nineteenth century to the promise and implications of ongoing research, David Bainbridge shows how the X evolved and where it and its counterpart Y are going, how it helps assign developing human babies their sex--and maybe even their sexuality--and how it affects our lives in infinitely complex and subtle ways. X offers cures for disease, challenges our cultural, ethical, and scientific assumptions about maleness and femaleness, and has even reshaped our views of human evolution and human nature. Table of Contents: Prologue 1. Making a Difference Interlude: What Is It, Exactly? 2. The Duke of Kent's Testicles Interlude: How Sexy Is X? 3. The Double Life of Women Epilogue: The Chosen One Further Reading Glossary Index Reviews of this book: The author of Making Babies takes a lively, witty tour of the X chromosome, creator of "a delicious symmetry between men and women"...Entertaining and informative...A fine demonstration of science made accessible. --Kirkus Reviews Reviews of this book: A well-written, well-researched, easy-to-read study that explains what has been learned about the X and Y chromosomes using DNA sequencing and other molecular biology techniques. British biologist Bainbridge...has pulled together historical and current scientific research about how the X and Y chromosomes affect us and what the genes on these chromosomes actually do, like causing sex-linked diseases and color blindness...An excellent example of good science writing...Recommended. --Margaret Henderson, Library Journal Reviews of this book: Bainbridge is an essentialist, interested in understanding what aspects of gender are biologically driven, and why...He has a central question he wants to answer. The question is not so much why men and women are different (a worn topic that's the subject of too many Mars-and-Venus bestsellers) but, far more specific and far more interesting: Why are men and women more different than they need to be? --Liza Mundy, Washington Post Reviews of this book: Bainbridge summarizes our knowledge of the genetic information that determines one's sex by recounting the ancients' speculations about the genesis of gender, following with modern biologists' discovery of the X and Y chromosomes about a century ago, and of the sex-determining gene Sry in the 1990s. In a discussion rich with history, evolution, and philosophy, Bainbridge points out the dramatic effect that gender selection has on people's lives...A fascinating, often humorous analysis of the science of sexuality. --Gilbert Taylor, Booklist Reviews of this book: In The X in Sex, David Bainbridge explains the far-reaching effects of X. Bainbridge...moves with ease between straightforward accounts of biology and historical stories about its effect, like the chapter describing the progression of hemophilia through the royal houses of Europe. Bainbridge discusses cultural history as well as natural history, and his wit enlivens every page. --Christine Kenneally, New York Times Book Review Reviews of this book: There are many literary stars (such as Stephen Jay Gould, Richard Dawkins and Matt Ridley) in the firmament of writers on evolution, and to a man they write with dash and persuasive logic. David Bainbridge is one such and in his latest book he takes the reader through the glories of the X chromosome at a cracking pace. --Miriam Stoppard, Times Higher Education Supplement (UK) Reviews of this book: The truth is that the behaviours of [chromosomes] X and Y are inextricably linked. Bainbridge explores this link in a compelling tale that takes in how the sex chromosomes became sex chromosomes, and the very different consequences of this for women and men. Along the way we encounter the Duke of Kent's testicles, calico cats and non-identical identical twin girls. His story weaves science, history and the history of science (with a little religion for good measure) in a straightforward, anecdotal fashion that will appeal to scientists and non-scientists alike. --Mark T. Ross, New Scientist (UK) Reviews of this book: In his structure/function analysis of the X chromosome, Bainbridge provides a tongue-in-cheek, yet informative, description of one of the two human sex chromosomes. --R. Adler, Choice Reviews of this book: If you have ever been intrigued by some of the puzzles of genetics--why boys tend to get haemophilia or colour blindness while girls are more likely to have an identical twin or to develop rheumatoid arthritis later in life--then The X in Sex is for you. --Chris Tyler-Smith, Times Literary Supplement David Bainbridge takes us on a fascinating tour of X chromosomes and explains what the possession of these intricately folded, infinitessimally narrow, two-inch long strings of genetic codes weighing almost nothing, means for their bearers--that is for each one of us, male and female. History and personal anecdotes are woven together with up-to-date summaries of the science, punctuated with Bainbridge's zany--and very British--humor, so that this information-packed book is pure pleasure to read. --Sarah Blaffer Hrdy author of Mother Nature: A History of Mothers, Infants, and Natural Selection The X in Sex is absolutely fascinating, so intriguing, in fact, that I found myself unwilling to put it down. David Bainbridge surveys an astonishing amount of new information from recent genomic studies of the X chromosome, clearly explaining the findings in a way the average person can easily follow. The science is presented via amusing and highly appropriate metaphors and clever turns of phrase, all of which serve to brighten the prose and present the reader with catchy ways to think about complex ideas. This is an informative, authoritative, and thoroughly enjoyable read: one of the best books I have read in recent years. --Jane Lancaster, University of New Mexico This is wonderful stuff--beautifully written, clear, jargon-free, with anecdotes sure to hold the attention. --other hupauthorTim Birkhead, author of Promiscuity: An Evolutionary History of Sperm Competition
Book Synopsis Sexual Reproduction in Animals and Plants by : Hitoshi Sawada
Download or read book Sexual Reproduction in Animals and Plants written by Hitoshi Sawada and published by Springer. This book was released on 2014-02-07 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the proceedings of the International Symposium on the Mechanisms of Sexual Reproduction in Animals and Plants, where many plant and animal reproductive biologists gathered to discuss their recent progress in investigating the shared mechanisms and factors involved in sexual reproduction. This now is the first book that reviews recent progress in almost all fields of plant and animal fertilization. It was recently reported that the self-sterile mechanism of a hermaphroditic marine invertebrate (ascidian) is very similar to the self-incompatibility system in flowering plants. It was also found that a male factor expressed in the sperm cells of flowering plants is involved in gamete fusion not only of plants but also of animals and parasites. These discoveries have led to the consideration that the core mechanisms or factors involved in sexual reproduction may be shared by animals, plants and unicellular organisms. This valuable book is highly useful for reproductive biologists as well as for biological scientists outside this field in understanding the current progress of reproductive biology.
