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Gating In Cerebral Networks
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Book Synopsis Gating in Cerebral Networks by : Mircea Steriade
Download or read book Gating in Cerebral Networks written by Mircea Steriade and published by Cambridge University Press. This book was released on 2007-09-13 with total page 79 pages. Available in PDF, EPUB and Kindle. Book excerpt: The correct functioning of the mammalian brain depends on the integrated activity of myriad neuronal and non-neuronal cells. Discrete areas serve discrete functions, and dispersed or distributed communities of cells serve others. Throughout, these networks of activity are under the control of neuromodulatory systems. One goal of current neuroscientific research is to elucidate the precise methods by which these systems operate, especially during normal conscious behaviours and processes. Mircea Steriade and Denis Paré describe the neuronal properties and networks that exist within and between the cortex and two important sub-cortical structures: the thalamus and amygdala. The authors explore the changes in these properties, covering topics including morphology, electrophysiology, architecture and gating; and comparing regions and systems in both normal and diseased states. Aimed at graduates and postdoctoral researchers in neuroscience.
Book Synopsis Gating in Cerebral Networks by : Mircea Steriade
Download or read book Gating in Cerebral Networks written by Mircea Steriade and published by Cambridge University Press. This book was released on 2007-09-13 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: The correct functioning of the mammalian brain depends on the integrated activity of myriad neuronal and non-neuronal cells. Discrete areas serve discrete functions, and dispersed or distributed communities of cells serve others. Throughout, these networks of activity are under the control of neuromodulatory systems. One goal of current neuroscientific research is to elucidate the precise methods by which these systems operate, especially during normal conscious behaviours and processes. Mircea Steriade and Denis Paré describe the neuronal properties and networks that exist within and between the cortex and two important sub-cortical structures: the thalamus and amygdala. The authors explore the changes in these properties, covering topics including morphology, electrophysiology, architecture and gating; and comparing regions and systems in both normal and diseased states. Aimed at graduates and postdoctoral researchers in neuroscience.
Book Synopsis Gating in Cerebral Networks by : Mircea Steriade
Download or read book Gating in Cerebral Networks written by Mircea Steriade and published by . This book was released on 2007 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: Describes how the many components of the mammalian brain interact under normal conditions and in diseased states.
Book Synopsis Gating Neuronal Activity in the Brain by : Janske G. P. Willems
Download or read book Gating Neuronal Activity in the Brain written by Janske G. P. Willems and published by . This book was released on 2019 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics by : Carl Faingold
Download or read book Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics written by Carl Faingold and published by Academic Press. This book was released on 2013-12-26 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics, edited by two leaders in the field, offers a current and complete review of what we know about neural networks. How the brain accomplishes many of its more complex tasks can only be understood via study of neuronal network control and network interactions. Large networks can undergo major functional changes, resulting in substantially different brain function and affecting everything from learning to the potential for epilepsy. With chapters authored by experts in each topic, this book advances the understanding of: - How the brain carries out important tasks via networks - How these networks interact in normal brain function - Major mechanisms that control network function - The interaction of the normal networks to produce more complex behaviors - How brain disorders can result from abnormal interactions - How therapy of disorders can be advanced through this network approach This book will benefit neuroscience researchers and graduate students with an interest in networks, as well as clinicians in neuroscience, pharmacology, and psychiatry dealing with neurobiological disorders. - Utilizes perspectives and tools from various neuroscience subdisciplines (cellular, systems, physiologic), making the volume broadly relevant - Chapters explore normal network function and control mechanisms, with an eye to improving therapies for brain disorders - Reflects predominant disciplinary shift from an anatomical to a functional perspective of the brain - Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available
Book Synopsis The Gating and Maintenance of sleep and Wake: New Circuits and Insights by : Michael Lazarus
Download or read book The Gating and Maintenance of sleep and Wake: New Circuits and Insights written by Michael Lazarus and published by Frontiers Media SA. This book was released on 2020-10-09 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Book Synopsis Fundamentals of Brain Network Analysis by : Alex Fornito
Download or read book Fundamentals of Brain Network Analysis written by Alex Fornito and published by Academic Press. This book was released on 2016-03-04 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Brain Network Analysis is a comprehensive and accessible introduction to methods for unraveling the extraordinary complexity of neuronal connectivity. From the perspective of graph theory and network science, this book introduces, motivates and explains techniques for modeling brain networks as graphs of nodes connected by edges, and covers a diverse array of measures for quantifying their topological and spatial organization. It builds intuition for key concepts and methods by illustrating how they can be practically applied in diverse areas of neuroscience, ranging from the analysis of synaptic networks in the nematode worm to the characterization of large-scale human brain networks constructed with magnetic resonance imaging. This text is ideally suited to neuroscientists wanting to develop expertise in the rapidly developing field of neural connectomics, and to physical and computational scientists wanting to understand how these quantitative methods can be used to understand brain organization. Winner of the 2017 PROSE Award in Biomedicine & Neuroscience and the 2017 British Medical Association (BMA) Award in Neurology Extensively illustrated throughout by graphical representations of key mathematical concepts and their practical applications to analyses of nervous systems Comprehensively covers graph theoretical analyses of structural and functional brain networks, from microscopic to macroscopic scales, using examples based on a wide variety of experimental methods in neuroscience Designed to inform and empower scientists at all levels of experience, and from any specialist background, wanting to use modern methods of network science to understand the organization of the brain
Book Synopsis Inhibitory Synaptic Plasticity by : Melanie A. Woodin
Download or read book Inhibitory Synaptic Plasticity written by Melanie A. Woodin and published by Springer Science & Business Media. This book was released on 2010-11-02 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume will explore the most recent findings on cellular mechanisms of inhibitory plasticity and its functional role in shaping neuronal circuits, their rewiring in response to experience, drug addiction and in neuropathology. Inhibitory Synaptic Plasticity will be of particular interest to neuroscientists and neurophysiologists.
Book Synopsis Jasper's Basic Mechanisms of the Epilepsies by : Jeffrey Noebels
Download or read book Jasper's Basic Mechanisms of the Epilepsies written by Jeffrey Noebels and published by OUP USA. This book was released on 2012-06-29 with total page 1258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.
Book Synopsis Neurobiology of Sensation and Reward by : Jay A. Gottfried
Download or read book Neurobiology of Sensation and Reward written by Jay A. Gottfried and published by CRC Press. This book was released on 2011-03-28 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesizing coverage of sensation and reward into a comprehensive systems overview, Neurobiology of Sensation and Reward presents a cutting-edge and multidisciplinary approach to the interplay of sensory and reward processing in the brain. While over the past 70 years these areas have drifted apart, this book makes a case for reuniting sensation a
Book Synopsis Handbook of Basal Ganglia Structure and Function by : Heinz Steiner
Download or read book Handbook of Basal Ganglia Structure and Function written by Heinz Steiner and published by Academic Press. This book was released on 2010-03-17 with total page 729 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Basal Ganglia comprise a group of forebrain nuclei that are interconnected with the cerebral cortex, thalamus and brainstem. Basal ganglia circuits are involved in various functions, including motor control and learning, sensorimotor integration, reward and cognition. The importance of these nuclei for normal brain function and behavior is emphasized by the numerous and diverse disorders associated with basal ganglia dysfunction, including Parkinson’s disease, Tourette’s syndrome, Huntington’s disease, obsessive-compulsive disorder, dystonia, and psychostimulant addiction. The Handbook of Basal Ganglia provides a comprehensive overview of the structural and functional organization of the basal ganglia, with special emphasis on the progress achieved over the last 10-15 years. Organized in six parts, the volume describes the general anatomical organization and provides a review of the evolution of the basal ganglia, followed by detailed accounts of recent advances in anatomy, cellular/molecular, and cellular/physiological mechanisms, and our understanding of the behavioral and clinical aspects of basal ganglia function and dysfunction. Synthesizes widely dispersed information on the behavioral neurobiology of the basal ganglia, including advances in the understanding of anatomy, cell-molecular and cell-physiological mechanisms, and behavioral/clinical aspects of function and dysfunction Features a truly international cast of the preeminent researchers in the field Fully explores the clinically relevant impact of the basal ganglia on various psychiatric and neurological diseases
Book Synopsis Salience Network of the Human Brain by : Lucina Q. Uddin
Download or read book Salience Network of the Human Brain written by Lucina Q. Uddin and published by Academic Press. This book was released on 2016-08-24 with total page 48 pages. Available in PDF, EPUB and Kindle. Book excerpt: Salience Network of the Human Brain focuses on the multiple sources of stimuli that compete for our attention, providing interesting discussions on how the relative salience—importance or prominence—of each of these inputs determines which ones we choose to focus on for more in-depth processing. The salience network is a collection of regions of the brain that select which stimuli are deserving of our attention. The network has key nodes in the insular cortex and is critical for detecting behaviorally relevant stimuli and for coordinating the brain’s neural resources in response to these stimuli. The insular cortex is a complex and multipurpose structure that plays a role in numerous cognitive functions related to perception, emotion, and interpersonal experience—and the failure of this network to function properly can lead to numerous neuropsychiatric disorders, including autism spectrum disorder, psychosis, and dementia. Presents the only publication available that summarizes our understanding of the salience network in one resource Authored by a leading research on this important aspect of attention Focuses on the multiple sources of stimuli that compete for our attention, providing interesting discussions on how the relative salience—importance or prominence—of each of these inputs determines which ones we choose to focus on for more in-depth processing
Book Synopsis The Cambridge Handbook of Consciousness by : Philip David Zelazo
Download or read book The Cambridge Handbook of Consciousness written by Philip David Zelazo and published by Cambridge University Press. This book was released on 2007-05-14 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Cambridge Handbook of Consciousness is the first of its kind in the field, and its appearance marks a unique time in the history of intellectual inquiry on the topic. After decades during which consciousness was considered beyond the scope of legitimate scientific investigation, consciousness re-emerged as a popular focus of research towards the end of the last century, and it has remained so for nearly 20 years. There are now so many different lines of investigation on consciousness that the time has come when the field may finally benefit from a book that pulls them together and, by juxtaposing them, provides a comprehensive survey of this exciting field. An authoritative desk reference, which will also be suitable as an advanced textbook.
Book Synopsis Micro-, Meso- and Macro-Connectomics of the Brain by : Henry Kennedy
Download or read book Micro-, Meso- and Macro-Connectomics of the Brain written by Henry Kennedy and published by Springer. This book was released on 2016-03-10 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has brought together leading investigators who work in the new arena of brain connectomics. This includes ‘macro-connectome’ efforts to comprehensively chart long-distance pathways and functional networks; ‘micro-connectome’ efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted brain regions; and ‘meso-connectome’ efforts to systematically map both local and long-distance connections using anatomical tracers. This book highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.
Download or read book Corticonics written by M. Abeles and published by Cambridge University Press. This book was released on 1991-02-22 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding how the brain works is probably the greatest scientific and intellectual challenge of our generation. The cerebral cortex is the instrument by which we carry the most complex mental functions. Fortunately, there exists an immense body of knowledge concerning both cortical structure and the properties of single neurons in the cortex. With the advent of the supercomputer, there has been increased interest in neural network modeling. What is needed is a new approach to an understanding of the mammalian cerebral cortex that will provide a link between the physiological description and the computer model. This book meets that need by combining anatomy, physiology, and modeling to achieve a quantitative description of cortical function. The material is presented didactically, starting with descriptive anatomy and comprehensively examining all aspects of modeling. The book gradually leads the reader from the macroscopic cortical anatomy and standard electrophysiological properties of single neurons to neural network models and synfire chains. The most modern trends in neural network modeling are explored.
Book Synopsis Animal and Translational Models for CNS Drug Discovery by : Robert A. McArthur
Download or read book Animal and Translational Models for CNS Drug Discovery written by Robert A. McArthur and published by Academic Press. This book was released on 2008-11-27 with total page 1367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal and Translational Models for CNS Drug Discovery combines the experience of academic, clinical and pharmaceutical neuroscientists in a unique collaborative approach to provide a greater understanding of the relevance of animal models of neuropsychiatric disorders and their role as translational tools for the discovery of CNS drugs being developed for the treatment of these disorders. The focus of this three-volume series of essays is to present a consensual picture of the translational value of animal models from leading experts actively involved in the use of animal models for understanding fundamental neurobiology of CNS disorders and the application of this knowledge to CNS drug discovery, and clinical investigators involved in clinical trials, drug development and eventual registration of novel pharmaceuticals. Each volume of the Animal and Translational Models for CNS Drug Discovery series is dedicated to the development and use of animal models in key therapeutic areas in psychiatric, neurologic and reward deficit disorders. Each volume has introductory chapters expressing the view of the role and relevance of animal models for CNS drug discovery and development from the perspective of (a) academic basic neuroscientific research, (b) applied pharmaceutical drug discovery and development, and (c) issues of clinical trial design and regulatory agencies limitations. Each volume examines the rationale, use, robustness and limitations of animal models in relevant therapeutic areas and discusses the use of animal models for target identification and validation. The clinical relevance of animal models is discussed in terms of major limitations in cross-species comparisons, clinical trial design of drug candidates, and how clinical trial endpoints could be improved. The aim of this series of volumes on Animal and Translational Models for CNS Drug Discovery is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery. - Provides clinical, academic, government and industry perspectives fostering integrated communication between principle participants at all stages of the drug discovery process - Critical evaluation of animal and translational models improving transition from drug discovery and clinical development - Emphasizes what results mean to the overall drug discovery process - Explores issues in clinical trial design and conductance in each therapeutic area - Each volume is available for purchase individually.
Book Synopsis The Neurobiology of Schizophrenia by : Ted Abel
Download or read book The Neurobiology of Schizophrenia written by Ted Abel and published by Academic Press. This book was released on 2016-07-08 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Neurobiology of Schizophrenia begins with an overview of the various facets and levels of schizophrenia pathophysiology, ranging systematically from its genetic basis over changes in neurochemistry and electrophysiology to a systemic neural circuits level. When possible, the editors point out connections between the various systems. The editors also depict methods and research strategies used in the respective field. The individual backgrounds of the two editors promote a synthesis between basic neuroscience and clinical relevance. Provides a comprehensive overview of neurobiological aspects of schizophrenia Discusses schizophrenia at behavioral, cognitive, clinical, electrophysiological, molecular, and genetic levels Edited by a translational researcher and a psychiatrist to promote synthesis between basic neuroscience and clinical relevance Elucidates connections between the various systems depicted, when possible
