Medical Applications of Mass Spectrometry

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Author :
Publisher : Elsevier
ISBN 13 : 0080554652
Total Pages : 607 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Medical Applications of Mass Spectrometry by : Karoly Vekey

Download or read book Medical Applications of Mass Spectrometry written by Karoly Vekey and published by Elsevier. This book was released on 2011-08-11 with total page 607 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass spectrometry is fast becoming an indispensable field for medical professionals. The mass spectrometric analysis of metabolites and proteins promises to revolutionize medical research and clinical diagnostics. As this technology rapidly enters the medical field, practicing professionals and students need to prepare to take full advantage of its capabilities. Medical Applications of Mass Spectrometry addresses the key issues in the medical applications of mass spectrometry at the level appropriate for the intended readership. It will go a long way to help the utilization of mass spectrometry in medicine.The book comprises five parts. A general overview is followed by a description of the basic sampling and separation methods in analytical chemistry. In the second part a solid foundation in mass spectrometry and modern techniques of data analysis is presented. The third part explains how mass spectrometry is used in exploring various classes of biomolecules, including proteins and lipids. In the fourth section mass spectrometry is introduced as a diagnostic tool in clinical treatment, infectious pathogen research, neonatal diagnostics, cancer, brain and allergy research, as well as in various fields of medicine: cardiology, pulmonology, neurology, psychiatric diseases, hemato-oncology, urologic diseases, gastrointestinal diseases, gynecology and pediatrics. The fifth part covers emerging applications in biomarker discovery and in mass spectrometric imaging.* Provides a broad look at how the medical field is benefiting from advances in mass spectrometry.* Guides the reader from basic principles and methods to cutting edge applications.* There is NO comparable book on the market to fill this fast growing field.

Ion/Molecule Attachment Reactions: Mass Spectrometry

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Author :
Publisher : Springer
ISBN 13 : 1489975888
Total Pages : 350 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis Ion/Molecule Attachment Reactions: Mass Spectrometry by : Toshihiro Fujii

Download or read book Ion/Molecule Attachment Reactions: Mass Spectrometry written by Toshihiro Fujii and published by Springer. This book was released on 2015-08-03 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the mechanism of alkali-metal ion/molecule association reaction, surveys the instrumental basis to study its kinetic, and describes the instrumentation to the measurement of alkali-metal ion affinities. The applications of the ion complexation mechanism in the condensed phase in reaction to direct analysis MS are also covered. Other topics include mechanism and reaction rate, experimental and theoretical ion affinities, applications of ion attachment reactions (IAR) to mass spectrometry such as alkali ion CIMS, ion attachment MS and cationization mass spectrometry of ESI, FAB, FD, LD, MALDI and SIMS and topics of IAR-based direct analysis mass spectrometry.

Fundamentals and Applications of Gas Phase Ion Chemistry

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Publisher : Springer Science & Business Media
ISBN 13 : 9780792354635
Total Pages : 520 pages
Book Rating : 4.3/5 (546 download)

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Book Synopsis Fundamentals and Applications of Gas Phase Ion Chemistry by : K.R. Jennings

Download or read book Fundamentals and Applications of Gas Phase Ion Chemistry written by K.R. Jennings and published by Springer Science & Business Media. This book was released on 1999 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book draws together leading workers in the fields of mass spectrometry and gas phase ion chemistry, providing a forum for the exchange of ideas and information. It contains 14 lecture summaries and accounts of seven workshops with contributions from Europe and North America.

Fundamentals and Applications of Fourier Transform Mass Spectrometry

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Publisher : Elsevier
ISBN 13 : 0128140143
Total Pages : 780 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Fundamentals and Applications of Fourier Transform Mass Spectrometry by : Philippe Schmitt-Kopplin

Download or read book Fundamentals and Applications of Fourier Transform Mass Spectrometry written by Philippe Schmitt-Kopplin and published by Elsevier. This book was released on 2019-08-11 with total page 780 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals and Applications of Fourier Transform Mass Spectrometry is the first book to delve into the underlying principles on the topic and their linkage to industrial applications. Drs. Schmitt-Kopplin and Kanawati have brought together a team of leading experts in their respective fields to present this technique from many different perspectives, describing, at length, the pros and cons of FT-ICR and Orbitrap. Numerous examples help researchers decide which instruments to use for their particular scientific problem and which data analysis methods should be applied to get the most out of their data. - Covers FT-ICR-MS and Orbitrap's fundamentals, enhancing researcher knowledge - Includes details on ion sources, data processing, chemical analysis and imaging - Provides examples across the wide spectrum of applications, including omics, environmental, chemical, pharmaceutical and food analysis

Activated Systems of Gas Phase Ion Molecule Reactions

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Author :
Publisher :
ISBN 13 :
Total Pages : 392 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Activated Systems of Gas Phase Ion Molecule Reactions by : Jason S. Wong

Download or read book Activated Systems of Gas Phase Ion Molecule Reactions written by Jason S. Wong and published by . This book was released on 2001 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Techniques for the Study of Ion-Molecule Reactions

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Author :
Publisher : Wiley-Interscience
ISBN 13 :
Total Pages : 680 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Techniques for the Study of Ion-Molecule Reactions by : James M. Farrar

Download or read book Techniques for the Study of Ion-Molecule Reactions written by James M. Farrar and published by Wiley-Interscience. This book was released on 1988-08-12 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first comprehensive collection of all the major techniques used to study gas phase interactions is presented in this volume. With complete coverage of what a given technique can accomplish, its advantages and disadvantages, the book is designed to teach advanced students and researchers entering the field how to investigate a broad range of topics. Included is coverage of traditional topics such as ion cyclotron resonance, as well as more recent innovations, including Fourier transform mass spectrometry and ionic cluster studies. Several diagrams of instrumentation and examples of experimental data are also provided.

Handbook of Pharmaceutical Analysis by HPLC

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Publisher : Elsevier
ISBN 13 : 0080455182
Total Pages : 679 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Handbook of Pharmaceutical Analysis by HPLC by : Satinder Ahuja

Download or read book Handbook of Pharmaceutical Analysis by HPLC written by Satinder Ahuja and published by Elsevier. This book was released on 2005-02-09 with total page 679 pages. Available in PDF, EPUB and Kindle. Book excerpt: High pressure liquid chromatography–frequently called high performance liquid chromatography (HPLC or, LC) is the premier analytical technique in pharmaceutical analysis and is predominantly used in the pharmaceutical industry. Written by selected experts in their respective fields, the Handbook of Pharmaceutical Analysis by HPLC Volume 6, provides a complete yet concise reference guide for utilizing the versatility of HPLC in drug development and quality control. Highlighting novel approaches in HPLC and the latest developments in hyphenated techniques, the book captures the essence of major pharmaceutical applications (assays, stability testing, impurity testing, dissolution testing, cleaning validation, high-throughput screening). A complete reference guide to HPLC Describes best practices in HPLC and offers 'tricks of the trade' in HPLC operation and method development Reviews key HPLC pharmaceutical applications and highlights currents trends in HPLC ancillary techniques, sample preparations, and data handling

Chiral Recognition in the Gas Phase

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Publisher : CRC Press
ISBN 13 : 1420082280
Total Pages : 250 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Chiral Recognition in the Gas Phase by : Anne Zehnacker

Download or read book Chiral Recognition in the Gas Phase written by Anne Zehnacker and published by CRC Press. This book was released on 2010-05-25 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding the molecular interactions responsible for chiral recognition is of primary importance in life chemistry. Gas-phase experiments on either neutral or ionic adducts of chiral molecules allow for the study of intrinsic properties of chiral recognition in solvent-free conditions. With contributions from a panel of international experts ex

Advances in Gas Phase Ion Chemistry

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Publisher : Elsevier
ISBN 13 : 0080550886
Total Pages : 281 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Advances in Gas Phase Ion Chemistry by :

Download or read book Advances in Gas Phase Ion Chemistry written by and published by Elsevier. This book was released on 1996-05-14 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Gas Phase Ion Chemistry

Chemical Ionization Mass Spectrometry

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Publisher : Routledge
ISBN 13 : 1351461532
Total Pages : 222 pages
Book Rating : 4.3/5 (514 download)

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Book Synopsis Chemical Ionization Mass Spectrometry by : Alex. G. Harrison

Download or read book Chemical Ionization Mass Spectrometry written by Alex. G. Harrison and published by Routledge. This book was released on 2018-05-11 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: The only comprehensive guide to CIMS applications in structural elucidation and analytical studies Chemical Ionization Mass Spectrometry, 2nd Edition, provides a comprehensive, up-to-date review of CIMS applications in structural elucidation and quantitative analytical studies. For the benefit of readers without a background in gaseous ion chemistry, a thorough review is presented in Chapter 2. Other chapters discuss such topics as reagent ion systems within the context of the thermochemistry and kinetics of the ionization process, including reactions and the type of information obtained; isotopic exchange reactions; stereochemical effects in chemical ionization; and reactive ion/molecule collisions in quadrupole cells. Chemical ionization mass spectra of 13 classes of compounds are discussed in detail to illustrate the influence of different functional groups on the spectra observed. Chemical Ionization Mass Spectrometry, 2nd Edition will be a valuable reference for anyone interested in mass spectrometry and gaseous ion chemistry in general.

Acyclic Hydrocarbons—Advances in Research and Application: 2012 Edition

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Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464995753
Total Pages : 422 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Acyclic Hydrocarbons—Advances in Research and Application: 2012 Edition by :

Download or read book Acyclic Hydrocarbons—Advances in Research and Application: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acyclic Hydrocarbons—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Acyclic Hydrocarbons. The editors have built Acyclic Hydrocarbons—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Acyclic Hydrocarbons in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Acyclic Hydrocarbons—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Energy Research Abstracts

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Publisher :
ISBN 13 :
Total Pages : 754 pages
Book Rating : 4.3/5 (129 download)

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Book Synopsis Energy Research Abstracts by :

Download or read book Energy Research Abstracts written by and published by . This book was released on 1993 with total page 754 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Gaseous Vanadium, Vanadium Oxide and Hydroxide Clusters

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Publisher : Logos Verlag Berlin GmbH
ISBN 13 : 3832520511
Total Pages : 211 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Gaseous Vanadium, Vanadium Oxide and Hydroxide Clusters by : Sandra Feyel

Download or read book Gaseous Vanadium, Vanadium Oxide and Hydroxide Clusters written by Sandra Feyel and published by Logos Verlag Berlin GmbH. This book was released on 2008 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present work explores the reactivities of gaseous vanadium, vanadium-oxide, and oxovanadium-hydroxide clusters toward methanol and small hydrocarbons. Various means of mass-spectrometric techniques, isotopic labeling studies, infrared photodissociation spectroscopy, and complementary DFT-calculations are employed for this purpose. Additionally, the hydrogen-atom abstraction process from methane by polynuclear metal oxides is discussed. This work contributes to a better understanding of the metal-oxide cluster's catalytic activity on a molecular scale.

Comprehensive Organometallic Chemistry II, Volume 7

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Publisher : Elsevier
ISBN 13 : 008096396X
Total Pages : 1071 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Comprehensive Organometallic Chemistry II, Volume 7 by : D.F. Schriver

Download or read book Comprehensive Organometallic Chemistry II, Volume 7 written by D.F. Schriver and published by Elsevier. This book was released on 2002-09-10 with total page 1071 pages. Available in PDF, EPUB and Kindle. Book excerpt: The section devoted to iron in this volume reflects the tremendous progress in the area. Specifically cluster chemistry, ligand transformations and detailed structural results are more prominent in COMC II. The organic chemistry of ruthenium and osmium is an area which has burgeoned during the period since the publication of COMC. This is especially true for the cluster chemistry of these elements, which have provided most of the advances in this important field. Consequently, this volume will include an update (1981-1993) of the chemistry of mono- and bi-nuclear complexes of ruthenium and osmium, with a rather more extensive treatment of tri- and tetra-nuclear complexes. This is because many of the early results in ruthenium and osmium cluster chemistry described in COMC are now much better understood and can thus be placed in a more general context. In the case of complexes containing clusters with five or more metal atoms, the coverage is essentially complete, again because this chemistry has developed during the 1980s.

Mass Spectrometry Handbook

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Publisher : John Wiley & Sons
ISBN 13 : 1118180720
Total Pages : 1362 pages
Book Rating : 4.1/5 (181 download)

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Book Synopsis Mass Spectrometry Handbook by : Mike S. Lee

Download or read book Mass Spectrometry Handbook written by Mike S. Lee and published by John Wiley & Sons. This book was released on 2012-04-16 with total page 1362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to its enormous sensitivity and ease of use, mass spectrometry has grown into the analytical tool of choice in most industries and areas of research. This unique reference provides an extensive library of methods used in mass spectrometry, covering applications of mass spectrometry in fields as diverse as drug discovery, environmental science, forensic science, clinical analysis, polymers, oil composition, doping, cellular research, semiconductor, ceramics, metals and alloys, and homeland security. The book provides the reader with a protocol for the technique described (including sampling methods) and explains why to use a particular method and not others. Essential for MS specialists working in industrial, environmental, and clinical fields.

Electrospray and MALDI Mass Spectrometry

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Publisher : John Wiley & Sons
ISBN 13 : 1118211553
Total Pages : 900 pages
Book Rating : 4.1/5 (182 download)

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Book Synopsis Electrospray and MALDI Mass Spectrometry by : Richard B. Cole

Download or read book Electrospray and MALDI Mass Spectrometry written by Richard B. Cole and published by John Wiley & Sons. This book was released on 2011-09-26 with total page 900 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover how advances in mass spectrometry are fueling new discoveries across a broad range of research areas Electrospray and MALDI Mass Spectrometry brings both veteran practitioners and beginning scientists up to date with the most recent trends and findings in electrospray ionization and matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. In particular, this Second Edition highlights how advances in electrospray and MALDI mass spectrometry are supporting important discoveries in new and emerging fields such as proteomics and metabolomics as well as in traditional areas of chemistry and physics research. Electrospray AND MALDI Mass Spectrometry, SECOND EDITION is divided into five parts: Part A, Fundamentals of ES, explains the fundamental phenomena underlying the electrospray process, including selectivity in ionization and inherent electrochemistry, and concludes with a chapter offering a comparative inventory of source hardware Part B, Fundamentals of MALDI, confronts ionization mechanisms, instrument development, and matrix selection, and includes a final chapter that explores the special application of MALDI to obtain two-dimensional images of spatial distributions of compounds on surfaces Part C, ES and MALDI Coupling to Mass Spectrometry Instrumentation, examines the coupling of these ionization techniques to various mass analyzers, including quadrupole ion trap, time-of-flight, Fourier transform ion cyclotron resonance, and ion mobility mass spectrometers Part D, Practical Aspects of ES and MALDI, investigates analytical issues including quantification, charge-state distributions, noncovalent interactions in solution that are preserved as gas-phase ions, and various means of ion excitation in preparation for tandem mass spectrometry, and offers a guide to the interpretation of even-electron mass spectra Part E, Biological Applications of ES and MALDI, examines the role of mass spectrometry in such areas as peptide and protein characterization, carbohydrate analysis, lipid analysis, and drug discovery Written by a team of leading experts, the book not only provides a critical review of the literature, but also presents key concepts in tutorial fashion to help readers take full advantage of the latest technological breakthroughs and applications. As a result, Electrospray and MALDI Mass Spectrometry will help researchers fully leverage the power of electrospray and MALDI mass spectrometry. The judicious compartmentalization of chapters, and the pedagogic presentation style throughout, render the book highly suitable for use as a text for graduate-level courses in advanced mass spectrometry.

MALDI Mass Spectrometry Imaging

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Author :
Publisher : Royal Society of Chemistry
ISBN 13 : 1839165200
Total Pages : 403 pages
Book Rating : 4.8/5 (391 download)

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Book Synopsis MALDI Mass Spectrometry Imaging by : Tiffany Porta Siegel

Download or read book MALDI Mass Spectrometry Imaging written by Tiffany Porta Siegel and published by Royal Society of Chemistry. This book was released on 2021-11-23 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gathers, in a single resource, knowledge about matrix-assisted laser desorption ionisation (MALDI) mass spectrometry imaging. It includes fundamentals in the MALDI ionisation process, different source geometries and capabilities, detection systems and the latest research and applications in the range of –omics area as well as other broader areas. Chapters will touch on dedicated sample preparation protocols specific for the class of compounds of interest, instrumentation used with strengths and current limitations, strategies for structural analysis and identification and applications. It will be a welcomed addition to the literature in this fast-moving field and provide a guide to new innovations and applications especially in metabolomics and proteomics. With contributions from leading experts, this book will be an authoritative guide to this method. Aimed at postgraduate and professional researchers, in academia and in the industrial market where it has direct application to clinical research. It will be a supporting volume for those just entering the field as well as experienced practitioners.