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Author :
Publisher :
ISBN 13 : 9781562384753
Total Pages : 40 pages
Book Rating : 4.3/5 (847 download)
Download or read book Gas chromatography / Mass spectrometry (GC/MS) confirmation of drugs : approved guideline written by and published by . This book was released on 2002 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Larry D. Bowers
Publisher :
ISBN 13 :
Total Pages : 40 pages
Book Rating : 4.:/5 (523 download)
Download or read book Gas Chromatography/mass Spectrometry (GC/MS) Confirmation of Drugs written by Larry D. Bowers and published by . This book was released on 2002 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : National Committee for Clinical Laboratory Standards
Publisher :
ISBN 13 : 9781562384036
Total Pages : 24 pages
Book Rating : 4.3/5 (84 download)
Download or read book Gas Chromatography/mass Spectrometry (GC/MS) Confirmation of Drugs; written by National Committee for Clinical Laboratory Standards and published by . This book was released on 2000 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Fulton G. Kitson
Publisher : Academic Press
ISBN 13 : 0080532322
Total Pages : 395 pages
Book Rating : 4.0/5 (85 download)
Download or read book Gas Chromatography and Mass Spectrometry written by Fulton G. Kitson and published by Academic Press. This book was released on 1996-08-30 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: This guide provides, under one cover, a wealth of practical information designed to facilitate the effectiveness of the GC/MS user. Separation conditions for numerous compound types are provided along with derivatized and underivatized compounds. A section on how to interpret mass spectral data, an extensive correlation of ion masses and neutral losses with possible structures, and examples of mass spectra are provided to further aid structure determination. Also included are basic information on instrumentation, ionization methods, quantitation, tips on the operation of mass spectrometers, the best derivatization procedures for a variety of compound types, troubleshooting techniques, and a variety of other information found to be useful to the practicing user of GC/MS instrumentation. This guide would be immediately valuable to the novice as well as the experienced GC/MS user who may not have the breadth of experience covered in this book. Key Features * Condenses and organizes recent and essential information for new and experienced GC/MS users * Comprehensively indexed and referenced * Includes practical methods of analysis * Serves as a text reference for short practical courses on the subject
Author : Rodger L. Foltz
Publisher :
ISBN 13 :
Total Pages : 214 pages
Book Rating : 4.:/5 (327 download)
Download or read book GC/MS Assays for Abused Drugs in Body Fluids written by Rodger L. Foltz and published by . This book was released on 1980 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Hari Nair
Publisher : Academic Press
ISBN 13 : 0128009926
Total Pages : 306 pages
Book Rating : 4.1/5 (28 download)
Download or read book Mass Spectrometry for the Clinical Laboratory written by Hari Nair and published by Academic Press. This book was released on 2016-11-02 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass Spectrometry for the Clinical Laboratory is an accessible guide to mass spectrometry and the development, validation, and implementation of the most common assays seen in clinical labs. It provides readers with practical examples for assay development, and experimental design for validation to meet CLIA requirements, appropriate interference testing, measuring, validation of ion suppression/matrix effects, and quality control. These tools offer guidance on what type of instrumentation is optimal for each assay, what options are available, and the pros and cons of each. Readers will find a full set of tools that are either directly related to the assay they want to adopt or for an analogous assay they could use as an example. Written by expert users of the most common assays found in a clinical laboratory (clinical chemists, toxicologists, and clinical pathologists practicing mass spectrometry), the book lays out how experts in the field have chosen their mass spectrometers, purchased, installed, validated, and brought them on line for routine testing. The early chapters of the book covers what the practitioners have learned from years of experience, the challenges they have faced, and their recommendations on how to build and validate assays to avoid problems. These chapters also include recommendations for maintaining continuity of quality in testing. The later parts of the book focuses on specific types of assays (therapeutic drugs, Vitamin D, hormones, etc.). Each chapter in this section has been written by an expert practitioner of an assay that is currently running in his or her clinical lab. Provides readers with the keys to choosing, installing, and validating a mass spectrometry platform Offers tools to evaluate, validate, and troubleshoot the most common assays seen in clinical pathology labs Explains validation, ion suppression, interference testing, and quality control design to the detail that is required for implementation in the lab
Author : B. J. Gudzinowicz
Publisher :
ISBN 13 : 9780783700328
Total Pages : 507 pages
Book Rating : 4.7/5 (3 download)
Download or read book Analysis of Drugs and Metabolites by Gas Chromatography written by B. J. Gudzinowicz and published by . This book was released on 1977 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Uttam Garg
Publisher : Springer Nature
ISBN 13 : 1071635417
Total Pages : 469 pages
Book Rating : 4.0/5 (716 download)
Download or read book Clinical Applications of Mass Spectrometry in Drug Analysis written by Uttam Garg and published by Springer Nature. This book was released on 2023-11-30 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fully updated volume describes methods and protocols for a number of drugs and toxins in a stepwise manner. Exploring the versatility and flexibility of mass spectrometry, the book covers the advantages of this technology, which typically include elimination of the need for special reagents such as antibodies, increased sensitivity and specificity, and multi-component analysis enabling the screening of tens to hundreds of compounds in a single assay run. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Clinical Applications of Mass Spectrometry in Drug Analysis: Methods and Protocols, Second Edition serves as a valuable resource for laboratory professionals who are already utilizing mass spectrometry or considering bringing this technology to their labs.
Author : Benjamin J. Gudzinowicz
Publisher : Marcel Dekker
ISBN 13 : 9780824768614
Total Pages : 612 pages
Book Rating : 4.7/5 (686 download)
Download or read book Analysis of Drugs and Metabolites by Gas Chromatography-Mass Spectometry written by Benjamin J. Gudzinowicz and published by Marcel Dekker. This book was released on 1980 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Danielle E. Ross-Carr
Publisher :
ISBN 13 :
Total Pages : 206 pages
Book Rating : 4.:/5 (12 download)
Download or read book Method Development and Validation for Drug Identification and Confirmation by LC/MS-MS for Limited-specimen Cases written by Danielle E. Ross-Carr and published by . This book was released on 2017 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Driving under the influence of drugs (DUID) cases represent the largest portion of cases handled in most forensic toxicology laboratories. Blood is a commonly used specimen and is often analyzed using gas chromatography-mass spectrometry (GC/MS). A common extraction for this method requires two milliliters of blood. If more than one extraction is necessary, a larger volume of blood is required. Recently, laboratories have started using liquid chromatography-mass spectrometry (LC/MS) to obtain a lower limit of detection and extractions which require less blood to complete. Currently, the Oklahoma State Bureau of Investigation (OSBI) Laboratory operates LC-based extractions which require 250 to 500 microliters (μL) of sample to complete, but these are limited to specific drug classes. A general drug screen for forty drugs has been developed and validated using 250 microliters of blood. Even with this reduction of volume requirements, there are still instances in which less than one milliliter (mL) of blood is available for use by the analyst. An additional validation has been completed which required 100 microliters of sample to confirm the presence of thirty-nine drugs. A comparison between these methods was completed to verify the sensitivity of the 100 microliter method.
Author : Benjamin J. Gudzinowicz
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (632 download)
Download or read book Analysis of Drugs and Metabolites by Gas Chromatography-mass Spectrometry written by Benjamin J. Gudzinowicz and published by . This book was released on 1977 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Benjamin J. Gudzinowicz
Publisher :
ISBN 13 : 9780835760140
Total Pages : 571 pages
Book Rating : 4.7/5 (61 download)
Download or read book Analysis of Drugs and Metabolites by Gas Chromatography written by Benjamin J. Gudzinowicz and published by . This book was released on 1980-01-01 with total page 571 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : McMaster M.
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (985 download)
Download or read book GC/MS (gas chromatography/mass spectrometry) - A Practical User's Guide written by McMaster M. and published by . This book was released on 1998 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Petra Gerhards
Publisher : Wiley-VCH
ISBN 13 :
Total Pages : 268 pages
Book Rating : 4.:/5 (321 download)
Download or read book GC/MS in Clinical Chemistry written by Petra Gerhards and published by Wiley-VCH. This book was released on 1999-02-22 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book enables the reader to gain a rapid understanding of GC/MS analysis through a basic knowledge of the fundamental principles, linking these with simple and practical applications in the field of industrial medicine and analysis of drugs. Additional information from other specialist fields is also provided with the aim of helping the analyst to understand their relevance to the interpretation of results. The book describes efficient methods of sample preparation and quality assurance and provides information on epidemiology and pharmacology, without which drug screening is impossible. This comprehensive overview is mainly written for the practical analyst in the clinical laboratory but it is equally suited for teaching purposes.
Author : Benjamin J. Gudzinowicz
Publisher :
ISBN 13 : 9780824766511
Total Pages : 568 pages
Book Rating : 4.7/5 (665 download)
Download or read book Analysis of Drugs and Meta-Bolites by Gas Chromotography-Mass Spectometry written by Benjamin J. Gudzinowicz and published by . This book was released on 1978 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Benjamin J. Gudzinowicz
Publisher : Marcel Dekker
ISBN 13 : 9780824767570
Total Pages : 472 pages
Book Rating : 4.7/5 (675 download)
Download or read book Cardiovascular, Antihypertensive, Hypoglycemic, and Thyroid-related Agents written by Benjamin J. Gudzinowicz and published by Marcel Dekker. This book was released on 1979 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Benjamin J. Gudzinowicz
Publisher :
ISBN 13 : 9780824766146
Total Pages : 484 pages
Book Rating : 4.7/5 (661 download)
Download or read book Central Nervous System Stimulants written by Benjamin J. Gudzinowicz and published by . This book was released on 1978 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt:
