Gangliosides And Neuronal Plasticity

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Gangliosides and Neuronal Plasticity

Author : G. Tettamanti
Publisher : Springer Science & Business Media
ISBN 13 : 1475753098
Total Pages : 477 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Gangliosides and Neuronal Plasticity by : G. Tettamanti

Download or read book Gangliosides and Neuronal Plasticity written by G. Tettamanti and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the Proceedings of the Meeting "Neuronal plasticity and gangliosides" which was held at Mantova, Italy, on May 29-31, 1985, as a satellite to the Tenth Meeting of the International Society for Neurochemistry, (Riva del Garda, Italy, May 19-24,1985). The Symposium took place in the "Teatro Bibiena", one of the oldest and most beautiful theatres in Italy, known for having been the place for some of the very first performances of W .A. Mozart. The number of registered participants in the Meeting was about 180 including 40 accor:Qpanying persons. The persons invited as Speakers or Chairmen of Colloquia and Workshops were 48. Eighteen countries were represented with the largest contingent coming from Italy, followed by Federal Republic of Germany, The United States, France and Great Britain. The Meeting was based on Colloquia, Workshops, Round Tables and Poster Sessions, with a total of 42 Lectures and 32 Poster presentations.

Gangliosides and Modulation of Neuronal Functions

Author : Hinrich Rahmann
Publisher : Springer Science & Business Media
ISBN 13 : 3642719325
Total Pages : 632 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Gangliosides and Modulation of Neuronal Functions by : Hinrich Rahmann

Download or read book Gangliosides and Modulation of Neuronal Functions written by Hinrich Rahmann and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: The NATO Advanced Research Workshop on "Gangliosides and Modu lation of Neuronal Functions" was held at the University of Stutt gart-Hohenheim, Federal Republic of Germany, on October 20 - 24, 1986. About 70 participants from 10 countries presented papers on a wide range of topics all concerning the ganglioside theme. The content of the workshop consisted of the following chap ters: (1) Fundamentals for research on function of gangliosides; (2) Brain ganglioside metabolism; (3) Cell specific distribution and differentiation-related ex pression of brain gangliosides; (4) Gangliosides and neuronal plasticity; (5) Bio-medical potential of exogenous ganglioside application on neuronal function; and (6) Critical assessments on aspects of ganglioside therapy. The aim of the workshop was to sum up and discuss the present knowledge in the respective fields. Despite intensive research on gangliosides ever since Ernst Klenk discovered them in 1936, the biological function of. these amphiphilic, "sphinx-like" glycosphingo lipids remains elusive. Over the past few years, several thousands of articles on gangliosides have been published demonstrating very special properties of these glycolipids and their possible in volvement in diverse biological phenomena. As far as we know up to the present time, these properties may be due to particular physico-chemical attributes of these compounds, especially in com bination with calcium. The results obtained so far have shed light not only on pos sible functional roles of gangliosides with regard to cellular induction and organization, but have also unexpectedly opened up VI a whole new field of therapeutic applications for these compounds.

Neuronal Plasticity and Trophic Factors

Author : Giovanni Biggio
Publisher :
ISBN 13 : 9783540967965
Total Pages : 152 pages
Book Rating : 4.9/5 (679 download)

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Book Synopsis Neuronal Plasticity and Trophic Factors by : Giovanni Biggio

Download or read book Neuronal Plasticity and Trophic Factors written by Giovanni Biggio and published by . This book was released on 1988 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Neurobiology of Gangliosides

Author : Alfredo Gorio
Publisher :
ISBN 13 :
Total Pages : 408 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Neurobiology of Gangliosides by : Alfredo Gorio

Download or read book Neurobiology of Gangliosides written by Alfredo Gorio and published by . This book was released on 1985 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Modulation of Neural and Behavioral Plasticity Following Intrahippocampal Injection of Colchicine by Gangliosides GM1 and AGF2

Author : Dwaine F. Emerich
Publisher :
ISBN 13 :
Total Pages : 180 pages
Book Rating : 4.:/5 (551 download)

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Book Synopsis Modulation of Neural and Behavioral Plasticity Following Intrahippocampal Injection of Colchicine by Gangliosides GM1 and AGF2 by : Dwaine F. Emerich

Download or read book Modulation of Neural and Behavioral Plasticity Following Intrahippocampal Injection of Colchicine by Gangliosides GM1 and AGF2 written by Dwaine F. Emerich and published by . This book was released on 1988 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Post-Lesion Neural Plasticity

Author : Hans Flohr
Publisher : Springer
ISBN 13 :
Total Pages : 736 pages
Book Rating : 4.:/5 (45 download)

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Book Synopsis Post-Lesion Neural Plasticity by : Hans Flohr

Download or read book Post-Lesion Neural Plasticity written by Hans Flohr and published by Springer. This book was released on 1988-11-11 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of a Symposium held at the University of Bremen in August 1987 as a Satellite Meeting of the Second World Congress of Neuroscience

Neuronal Plasticity and Memory Formation

Author : Cosimo Ajmone Marsan
Publisher :
ISBN 13 :
Total Pages : 696 pages
Book Rating : 4.:/5 (45 download)

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Book Synopsis Neuronal Plasticity and Memory Formation by : Cosimo Ajmone Marsan

Download or read book Neuronal Plasticity and Memory Formation written by Cosimo Ajmone Marsan and published by . This book was released on 1982 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Chemistry of Behavior

Author : Stanislav Reinis
Publisher : Springer
ISBN 13 :
Total Pages : 632 pages
Book Rating : 4.:/5 (45 download)

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Book Synopsis The Chemistry of Behavior by : Stanislav Reinis

Download or read book The Chemistry of Behavior written by Stanislav Reinis and published by Springer. This book was released on 1982-09-30 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses a particular aspect of brain function, that of storage and retrieval of memory of past experience, in terms of neuronal plasticity. In discussing this aspect of brain functions, however, it discusses brain mecha nisms in their wider sense as well. Clearly, the central nervous system is a highly interconnected system from all points of view, and it would not be possible to understand function in terms of only a single event or only a sin gle neurotransmitter. This is true for any biochemical activity that accompanies neuronal functional activity and accompanies behavior. The authors have commendably recognized this complexity, and recognize still more the need to present information in a compact and uniform manner in spite of the tremendous expansion of our knowledge in recent years. It is a somewhat easier task to gather a set of authors and record their results for a multiauthor symposium, but it is a most admirable endeavor for two authors to summarize a field that encompasses subjects such as transmission barri ers, lipids, proteins, energy, hormones, to name a few that this book covers so well in a compact manner, and in such depth as well. Metabolism and func tion cannot really be understood without understanding structural factors, changes in membrane properties, and changes in metabolism.

GM3 Signaling

Author : Cheorl-Ho Kim
Publisher : Springer Nature
ISBN 13 : 9811556520
Total Pages : 135 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis GM3 Signaling by : Cheorl-Ho Kim

Download or read book GM3 Signaling written by Cheorl-Ho Kim and published by Springer Nature. This book was released on 2020-07-10 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews recent progress in understanding of the signaling and biochemistry of GM3 ganglioside in eukaryotic cells. GM3 is the simplest of the gangliosides and the precursor of other gangliosides. It is expressed in the outer leaflet of plasma cell membranes and has roles in the recognition, interaction, binding, adhesion, and motility of cells. In addition, GM3 has been documented to have functional roles in cell migration, proliferation, senescence, and apoptosis. The full range of topics of interest are addressed in the book. The early chapters discuss the synthesis of GM3, its molecular localization in cells, and its basic function as an interacting molecule. The ways in which GM3 exerts its effects via various growth factor receptors are fully explored. Current knowledge of the part played by GM3 in health and disease is discussed in depth. For example, its roles in preventing inflammation, inhibiting tumor angiogenesis and tumor growth, and suppressing arthritis are highlighted, and attention drawn to the significance of GM3 as a driver of impaired wound healing in diabetics. The book will be of interest to all who want a comprehensive update on research in this field.

Brain Lipids in Synaptic Function and Neurological Disease

Author : Jacques Fantini
Publisher : Academic Press
ISBN 13 : 0128004924
Total Pages : 398 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Brain Lipids in Synaptic Function and Neurological Disease by : Jacques Fantini

Download or read book Brain Lipids in Synaptic Function and Neurological Disease written by Jacques Fantini and published by Academic Press. This book was released on 2015-05-12 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lipids are the most abundant organic compounds found in the brain, accounting for up to 50% of its dry weight. The brain lipidome includes several thousands of distinct biochemical structures whose expression may greatly vary according to age, gender, brain region, cell type, as well as subcellular localization. In synaptic membranes, brain lipids specifically interact with neurotransmitter receptors and control their activity. Moreover, brain lipids play a key role in the generation and neurotoxicity of amyloidogenic proteins involved in the pathophysiology of neurological diseases. The aim of this book is to provide for the first time a comprehensive overview of brain lipid structures, and to explain the roles of these lipids in synaptic function, and in neurodegenerative diseases, including Alzheimer’s, Creutzfeldt-Jakob’s and Parkinson’s. To conclude the book, the authors present new ideas that can drive innovative therapeutic strategies based on the knowledge of the role of lipids in brain disorders. Written to provide a "hands-on" approach for readers Biochemical structures explained with molecular models, and molecular mechanisms explained with simple drawings Step-by-step guide to memorize and draw lipid structures Each chapter features a content summary, up-to-date references for additional study, and a key experiment with an explanation of the technique

The Sugar Code

Author : Hans-Joachim Gabius
Publisher : John Wiley & Sons
ISBN 13 : 3527644946
Total Pages : 560 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis The Sugar Code by : Hans-Joachim Gabius

Download or read book The Sugar Code written by Hans-Joachim Gabius and published by John Wiley & Sons. This book was released on 2011-09-19 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: A reader friendly overview of the structure and functional relevance of natural glycosylation and its cognate proteins (lectins), this book is also one of the few books to cover their role in health and disease. Edited by one of the pioneering experts in the field and written by a team of renowned researchers this resource is a perfect introduction for all students in life and medical sciences, biochemistry, chemistry and pharmacy. Website: WWW.WILEY-VCH.DE/HOME/THESUGARCODE

Progressive Brain Disorders in Childhood

Author : Juan M. Pascual
Publisher : Cambridge University Press
ISBN 13 : 1107042054
Total Pages : 507 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Progressive Brain Disorders in Childhood by : Juan M. Pascual

Download or read book Progressive Brain Disorders in Childhood written by Juan M. Pascual and published by Cambridge University Press. This book was released on 2017-04-20 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: A review of childhood neurodegenerative and other progressive but non-degenerative disorders to guide their diagnosis and management.

Brain Neurotrauma

Author : Firas H. Kobeissy
Publisher : CRC Press
ISBN 13 : 1466565993
Total Pages : 718 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Brain Neurotrauma by : Firas H. Kobeissy

Download or read book Brain Neurotrauma written by Firas H. Kobeissy and published by CRC Press. This book was released on 2015-02-25 with total page 718 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.

Ganglioside Biochemistry

Author : Cheorl-Ho Kim
Publisher : Springer Nature
ISBN 13 : 9811558159
Total Pages : 223 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Ganglioside Biochemistry by : Cheorl-Ho Kim

Download or read book Ganglioside Biochemistry written by Cheorl-Ho Kim and published by Springer Nature. This book was released on 2020-07-03 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest knowledge and the most recent research results in the field of ganglioside biochemistry. The early chapters cover all relevant background on sialic acids and their biosynthesis, on N-glycolylneuraminic acid (Neu5Gc), which cannot be synthesized by humans, and on general aspects of ganglioside research. Ganglioside adsorption, disorders of ganglioside degradation, and the regulation of gangliosides are thoroughly discussed. A major focus of the book is the role of gangliosides in cancer. Here, the discussion encompasses, for example, the biological importance, antigenicity, and immunological actions of tumor-associated gangliosides (TAGs), the significance of different glycolipids and gangliosides as TAGs, and emerging anti-cancer vaccine strategies. The ability of sialic acids and TAGs of tumor cells to escape immunosurveillance and immunoediting also receives detailed attention. The significance of sialic acids in regulation of the complement system is explained, and the closing chapter focuses especially on the role of sialyl T antigen in cancer. The book will be of value for all who are interested in functional glycobiology and glycomic studies.

Trophic Regulation of the Basal Ganglia

Author : K. Fuxe
Publisher : Elsevier
ISBN 13 : 1483103099
Total Pages : 629 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Trophic Regulation of the Basal Ganglia by : K. Fuxe

Download or read book Trophic Regulation of the Basal Ganglia written by K. Fuxe and published by Elsevier. This book was released on 2013-10-22 with total page 629 pages. Available in PDF, EPUB and Kindle. Book excerpt: Trophic Regulation of the Basal Ganglia: Focus on Dopamine Neurons examines neurotransmitters. The book first discusses the role of fibroblast growth factor-2 (FGF-2) and ganglioside GM1 and the trophic regulation of the basal ganglia. Biochemical and histochemical studies on the cellular localization of FGF-2; mapping of FGF-2 and its receptors in the basal ganglia postnatally and adulthood; and mapping of the ganglioside GM1 distribution in the basal ganglia are presented. The text also explains glucocorticoid and estrogen effects on the nigrostriatal and mesolimbic dopaminergic systems; factors associated to dopaminergic cell death in Parkinson's disease; and compensatory mechanisms at dopamine D-2 receptors. The book also describes the effects of brain-derived neurotrophic factor on injured dopaminergic neurons; role of gangliosides and trophic factors in brain repair; and features of the trophic action of polyamines. The text also underscores the presence of interleukin-1 in the central nervous system; neuropeptides synthesis in astrocytes; and astrocytic kynurenines as modulators of dopaminergic function in the rat basal ganglia. The selection is a good source of information for readers wanting to study neurotransmitters.

Neuroglycobiology

Author : Minoru Fukuda
Publisher : Oxford University Press, USA
ISBN 13 : 9780198525387
Total Pages : 272 pages
Book Rating : 4.5/5 (253 download)

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Book Synopsis Neuroglycobiology by : Minoru Fukuda

Download or read book Neuroglycobiology written by Minoru Fukuda and published by Oxford University Press, USA. This book was released on 2005 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbohydrates play a major role in brain function. In the past decade, tremendous progress has been made in understanding their structure and function within the nervous system. This book presents a state of the art account of this rapidly expanding field.

Adverse Effects of Vaccines

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309214351
Total Pages : 894 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Adverse Effects of Vaccines by : Institute of Medicine

Download or read book Adverse Effects of Vaccines written by Institute of Medicine and published by National Academies Press. This book was released on 2012-04-26 with total page 894 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1900, for every 1,000 babies born in the United States, 100 would die before their first birthday, often due to infectious diseases. Today, vaccines exist for many viral and bacterial diseases. The National Childhood Vaccine Injury Act, passed in 1986, was intended to bolster vaccine research and development through the federal coordination of vaccine initiatives and to provide relief to vaccine manufacturers facing financial burdens. The legislation also intended to address concerns about the safety of vaccines by instituting a compensation program, setting up a passive surveillance system for vaccine adverse events, and by providing information to consumers. A key component of the legislation required the U.S. Department of Health and Human Services to collaborate with the Institute of Medicine to assess concerns about the safety of vaccines and potential adverse events, especially in children. Adverse Effects of Vaccines reviews the epidemiological, clinical, and biological evidence regarding adverse health events associated with specific vaccines covered by the National Vaccine Injury Compensation Program (VICP), including the varicella zoster vaccine, influenza vaccines, the hepatitis B vaccine, and the human papillomavirus vaccine, among others. For each possible adverse event, the report reviews peer-reviewed primary studies, summarizes their findings, and evaluates the epidemiological, clinical, and biological evidence. It finds that while no vaccine is 100 percent safe, very few adverse events are shown to be caused by vaccines. In addition, the evidence shows that vaccines do not cause several conditions. For example, the MMR vaccine is not associated with autism or childhood diabetes. Also, the DTaP vaccine is not associated with diabetes and the influenza vaccine given as a shot does not exacerbate asthma. Adverse Effects of Vaccines will be of special interest to the National Vaccine Program Office, the VICP, the Centers for Disease Control and Prevention, vaccine safety researchers and manufacturers, parents, caregivers, and health professionals in the private and public sectors.