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Author : Samira Hosseini
Publisher :
ISBN 13 : 9789811023576
Total Pages : 68 pages
Book Rating : 4.0/5 (235 download)
Download or read book Fundamentals of MALDI-ToF-MS Analysis written by Samira Hosseini and published by . This book was released on 2017 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Samira Hosseini
Publisher : Springer
ISBN 13 : 9811023565
Total Pages : 68 pages
Book Rating : 4.8/5 (11 download)
Download or read book Fundamentals of MALDI-ToF-MS Analysis written by Samira Hosseini and published by Springer. This book was released on 2016-08-18 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the fundamentals and applications of Matrix Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-ToF-MS) technique. It highlights the basic principles, the history of invention as well as the mechanism of ionization and mass determination using this technique. It describes the fundamental principles and methods for MALDI spectra interpretation and determination of exact chemical structures from experimental data. This book guides the reader through the interpretation of MALDI data where complex macromolecular spectra are simplified in order to present the major principles behind data interpretation. In addition, each chapter describes how MALDI-ToF-MS analysis provides necessary understanding of the copolymer systems that have been designed for specialized biomedical applications.
Author : Chhabil Dass
Publisher : John Wiley & Sons
ISBN 13 : 0470118482
Total Pages : 512 pages
Book Rating : 4.4/5 (71 download)
Download or read book Fundamentals of Contemporary Mass Spectrometry written by Chhabil Dass and published by John Wiley & Sons. This book was released on 2007-05-11 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern mass spectrometry - the instrumentation and applications in diverse fields Mass spectrometry has played a pivotal role in a variety of scientific disciplines. Today it is an integral part of proteomics and drug discovery process. Fundamentals of Contemporary Mass Spectrometry gives readers a concise and authoritative overview of modern mass spectrometry instrumentation, techniques, and applications, including the latest developments. After an introduction to the history of mass spectrometry and the basic underlying concepts, it covers: Instrumentation, including modes of ionization, condensed phase ionization techniques, mass analysis and ion detection, tandem mass spectrometry, and hyphenated separation techniques Organic and inorganic mass spectrometry Biological mass spectrometry, including the analysis of proteins and peptides, oligosaccharides, lipids, oligonucleotides, and other biological materials Applications to quantitative analysis Based on proven teaching principles, each chapter is complete with a concise overview, highlighted key points, practice exercises, and references to additional resources. Hints and solutions to the exercises are provided in an appendix. To facilitate learning and improve problem-solving skills, several worked-out examples are included. This is a great textbook for graduate students in chemistry, and a robust, practical resource for researchers and scientists, professors, laboratory managers, technicians, and others. It gives scientists in diverse disciplines a practical foundation in modern mass spectrometry.
Author : Richard B. Cole
Publisher : John Wiley & Sons
ISBN 13 : 1118211553
Total Pages : 900 pages
Book Rating : 4.1/5 (182 download)
Download or read book Electrospray and MALDI Mass Spectrometry written by Richard B. Cole and published by John Wiley & Sons. This book was released on 2011-09-26 with total page 900 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover how advances in mass spectrometry are fueling new discoveries across a broad range of research areas Electrospray and MALDI Mass Spectrometry brings both veteran practitioners and beginning scientists up to date with the most recent trends and findings in electrospray ionization and matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. In particular, this Second Edition highlights how advances in electrospray and MALDI mass spectrometry are supporting important discoveries in new and emerging fields such as proteomics and metabolomics as well as in traditional areas of chemistry and physics research. Electrospray AND MALDI Mass Spectrometry, SECOND EDITION is divided into five parts: Part A, Fundamentals of ES, explains the fundamental phenomena underlying the electrospray process, including selectivity in ionization and inherent electrochemistry, and concludes with a chapter offering a comparative inventory of source hardware Part B, Fundamentals of MALDI, confronts ionization mechanisms, instrument development, and matrix selection, and includes a final chapter that explores the special application of MALDI to obtain two-dimensional images of spatial distributions of compounds on surfaces Part C, ES and MALDI Coupling to Mass Spectrometry Instrumentation, examines the coupling of these ionization techniques to various mass analyzers, including quadrupole ion trap, time-of-flight, Fourier transform ion cyclotron resonance, and ion mobility mass spectrometers Part D, Practical Aspects of ES and MALDI, investigates analytical issues including quantification, charge-state distributions, noncovalent interactions in solution that are preserved as gas-phase ions, and various means of ion excitation in preparation for tandem mass spectrometry, and offers a guide to the interpretation of even-electron mass spectra Part E, Biological Applications of ES and MALDI, examines the role of mass spectrometry in such areas as peptide and protein characterization, carbohydrate analysis, lipid analysis, and drug discovery Written by a team of leading experts, the book not only provides a critical review of the literature, but also presents key concepts in tutorial fashion to help readers take full advantage of the latest technological breakthroughs and applications. As a result, Electrospray and MALDI Mass Spectrometry will help researchers fully leverage the power of electrospray and MALDI mass spectrometry. The judicious compartmentalization of chapters, and the pedagogic presentation style throughout, render the book highly suitable for use as a text for graduate-level courses in advanced mass spectrometry.
Author : Tiffany Siegel Porta
Publisher : Royal Society of Chemistry
ISBN 13 : 1839162414
Total Pages : 541 pages
Book Rating : 4.8/5 (391 download)
Download or read book MALDI Mass Spectrometry Imaging written by Tiffany Siegel Porta and published by Royal Society of Chemistry. This book was released on 2021-12-03 with total page 541 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gathers knowledge about matrix-assisted laser desorption ionisation (MALDI) mass spectrometry imaging for postgraduate and professional researchers in academia and in industry where it has direct application to clinical research.
Author : Harald Pasch
Publisher : Springer Science & Business Media
ISBN 13 : 3662050463
Total Pages : 312 pages
Book Rating : 4.6/5 (62 download)
Download or read book MALDI-TOF Mass Spectrometry of Synthetic Polymers written by Harald Pasch and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: MALDI-TOF mass spectrometry is one of the latest and most fascinating new developments in the analysis of organic compounds. Originally developed for the analysis of biomolecules, it has developed into one of the most powerful techniques for the characterization of synthetic polymers. This book describes the fundamentals of the MALDI process and the technical features of MALDI-TOF instrumentation. It reviews the application of MALDI-TOF for identification, chemical and molar mass analysis of synthetic polymers. With many examples, the monograph examines experimental protocols for the determination of endgroups, the analysis of copolymers and additives, and the coupling of liquid chromatography and MALDI-TOF in detail.
Author : Carl A. Burtis
Publisher : Elsevier Health Sciences
ISBN 13 : 0323292062
Total Pages : 1102 pages
Book Rating : 4.3/5 (232 download)
Download or read book Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics - E-Book written by Carl A. Burtis and published by Elsevier Health Sciences. This book was released on 2014-02-26 with total page 1102 pages. Available in PDF, EPUB and Kindle. Book excerpt: A condensed, easier-to-understand student version of the acclaimed Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, 7th Edition uses a laboratory perspective in providing the clinical chemistry fundamentals you need to work in a real-world, clinical lab. Coverage ranges from laboratory principles to analytical techniques and instrumentation, analytes, pathophysiology, and more. New content keeps you current with the latest developments in molecular diagnostics. From highly respected clinical chemistry experts Carl Burtis and David Bruns, this textbook shows how to select and perform diagnostic lab tests, and accurately evaluate results. Authoritative, respected author team consists of two well-known experts in the clinical chemistry world. Coverage of analytical techniques and instrumentation includes optical techniques, electrochemistry, electrophoresis, chromatography, mass spectrometry, enzymology, immunochemical techniques, microchips, automation, and point of care testing. Learning objectives begin each chapter, providing measurable outcomes to achieve after completing the material. Key words are listed and defined at the beginning of each chapter, and bolded in the text. A glossary at the end of the book makes it quick and easy to look up definitions of key terms. More than 500 illustrations plus easy-to-read tables help you understand and remember key concepts. New chapters on molecular diagnostics include the principles of molecular biology, nucleic acid techniques and applications, and genomes and nucleic acid alterations, reflecting the changes in this rapidly evolving field. New content on clinical evaluation of methods, kidney function tests, and diabetes is added to this edition. NEW multiple-choice review questions at the end of each chapter allow you to measure your comprehension of the material. NEW case studies on the Evolve companion website use real-life scenarios to reinforce concepts.
Author : Rainer Cramer
Publisher : Springer
ISBN 13 : 3319048198
Total Pages : 286 pages
Book Rating : 4.3/5 (19 download)
Download or read book Advances in MALDI and Laser-Induced Soft Ionization Mass Spectrometry written by Rainer Cramer and published by Springer. This book was released on 2015-11-09 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the state-of-the-art of modern MALDI (matrix-assisted laser desorption/ionization) and its applications. New applications and improvements in the MALDI field such as biotyping, clinical diagnosis, forensic imaging, and ESI-like ion production are covered in detail. Additional topics include MS imaging, biotyping/speciation and large-scale, high-speed MS sample profiling, new methods based on MALDI or MALDI-like sample preparations, and the advantages of ESI to MALDI MS analysis. This is an ideal book for graduate students and researchers in the field of bioanalytical sciences. This book also: • Showcases new techniques and applications in MALDI MS • Demonstrates how MALDI is preferable to ESI (electrospray ionization) • Illustrates the pros and cons associated with biomarker discovery studies in clinical proteomics and the various application areas, such as cancer proteomics
Author :
Publisher : Elsevier
ISBN 13 : 008101984X
Total Pages : 5142 pages
Book Rating : 4.0/5 (81 download)
Download or read book Encyclopedia of Analytical Science written by and published by Elsevier. This book was released on 2019-04-02 with total page 5142 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of the Encyclopedia of Analytical Science, Ten Volume Set is a definitive collection of articles covering the latest technologies in application areas such as medicine, environmental science, food science and geology. Meticulously organized, clearly written and fully interdisciplinary, the Encyclopedia of Analytical Science, Ten Volume Set provides foundational knowledge across the scope of modern analytical chemistry, linking fundamental topics with the latest methodologies. Articles will cover three broad areas: analytical techniques (e.g., mass spectrometry, liquid chromatography, atomic spectrometry); areas of application (e.g., forensic, environmental and clinical); and analytes (e.g., arsenic, nucleic acids and polycyclic aromatic hydrocarbons), providing a one-stop resource for analytical scientists. Offers readers a one-stop resource with access to information across the entire scope of modern analytical science Presents articles split into three broad areas: analytical techniques, areas of application and and analytes, creating an ideal resource for students, researchers and professionals Provides concise and accessible information that is ideal for non-specialists and readers from undergraduate levels and higher
Author : Chunlong Zhang
Publisher : John Wiley & Sons
ISBN 13 : 0471710970
Total Pages : 459 pages
Book Rating : 4.4/5 (717 download)
Download or read book Fundamentals of Environmental Sampling and Analysis written by Chunlong Zhang and published by John Wiley & Sons. This book was released on 2007-03-09 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: An integrated approach to understanding the principles of sampling, chemical analysis, and instrumentation This unique reference focuses on the overall framework and why various methodologies are used in environmental sampling and analysis. An understanding of the underlying theories and principles empowers environmental professionals to select and adapt the proper sampling and analytical protocols for specific contaminants as well as for specific project applications. Covering both field sampling and laboratory analysis, Fundamentals of Environmental Sampling and Analysis includes: A review of the basic analytical and organic chemistry, statistics, hydrogeology, and environmental regulations relevant to sampling and analysis An overview of the fundamentals of environmental sampling design, sampling techniques, and quality assurance/quality control (QA/QC) essential to acquire quality environmental data A detailed discussion of: the theories of absorption spectroscopy for qualitative and quantitative environmental analysis; metal analysis using various atomic absorption and emission spectrometric methods; and the instrumental principles of common chromatographic and electrochemical methods An introduction to advanced analytical techniques, including various hyphenated mass spectrometries and nuclear magnetic resonance spectroscopy With real-life case studies that illustrate the principles plus problems and questions at the end of each chapter to solidify understanding, this is a practical, hands-on reference for practitioners and a great textbook for upper-level undergraduates and graduate students in environmental science and engineering.
Author : Robert K. Boyd
Publisher : John Wiley & Sons
ISBN 13 : 1119964393
Total Pages : 1179 pages
Book Rating : 4.1/5 (199 download)
Download or read book Trace Quantitative Analysis by Mass Spectrometry written by Robert K. Boyd and published by John Wiley & Sons. This book was released on 2011-08-24 with total page 1179 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a serious introduction to the subject of mass spectrometry, providing the reader with the tools and information to be well prepared to perform such demanding work in a real-life laboratory. This essential tool bridges several subjects and many disciplines including pharmaceutical, environmental and biomedical analysis that are utilizing mass spectrometry: Covers all aspects of the use of mass spectrometry for quantitation purposes Written in textbook style to facilitate understanding of this topic Presents fundamentals and real-world examples in a ‘learning-though-doing’ style
Author : Yongdong Zhu
Publisher :
ISBN 13 :
Total Pages : 364 pages
Book Rating : 4.3/5 (91 download)
Download or read book Fundamental Studies of Matrix-assisted Laser Desorption/ionization Time-of-flight Mass Spectrometry (MALDI-TOF/MS) and Its Applications to the Analysis of Biological Materials written by Yongdong Zhu and published by . This book was released on 1999 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Philippe Schmitt-Kopplin
Publisher : Elsevier
ISBN 13 : 0128140143
Total Pages : 778 pages
Book Rating : 4.1/5 (281 download)
Download or read book Fundamentals and Applications of Fourier Transform Mass Spectrometry written by Philippe Schmitt-Kopplin and published by Elsevier. This book was released on 2019-08-11 with total page 778 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals and Applications of Fourier Transform Mass Spectrometry is the first book to delve into the underlying principles on the topic and their linkage to industrial applications. Drs. Schmitt-Kopplin and Kanawati have brought together a team of leading experts in their respective fields to present this technique from many different perspectives, describing, at length, the pros and cons of FT-ICR and Orbitrap. Numerous examples help researchers decide which instruments to use for their particular scientific problem and which data analysis methods should be applied to get the most out of their data. Covers FT-ICR-MS and Orbitrap’s fundamentals, enhancing researcher knowledge Includes details on ion sources, data processing, chemical analysis and imaging Provides examples across the wide spectrum of applications, including omics, environmental, chemical, pharmaceutical and food analysis
Author : Phuong Nguyen Tri
Publisher : Elsevier
ISBN 13 : 0128168919
Total Pages : 558 pages
Book Rating : 4.1/5 (281 download)
Download or read book Smart Nanocontainers written by Phuong Nguyen Tri and published by Elsevier. This book was released on 2019-11-08 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: Smart Nanocontainers explores the fundamental concepts and emerging applications of nanocontainers in biomedicine, pharmaceuticals and smart materials. In pharmaceuticals, nanocontainers have advantages over their micro-counterparts, including more efficient drug detoxification, higher intracellular uptake, better stability, less side effects and higher biocompatibility with tissue and cells. In materials science, such as coating technology, they help by making coatings smarter, stronger and more durable. This important reference will help anyone who wants to learn more on how nanocontainers are used to provide the controlled release of active agents, including their applications in smart coatings, corrosion, drug delivery, diagnosis, agri-food and gas storage. Discusses how the molecular design of nanocarriers can be optimized to increase performance Explores how nanocarriers are being used to produce a new generation of active coatings Explains how nanocarriers are being used to deliver more effective nanoscale drug delivery
Author : Rasel Das
Publisher : Springer Nature
ISBN 13 : 9819954835
Total Pages : 231 pages
Book Rating : 4.8/5 (199 download)
Download or read book Electrospun Nanofibrous Technology for Clean Water Production written by Rasel Das and published by Springer Nature. This book was released on 2023-10-14 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the remarkable progress in the field of electrospun nanofibrous materials synthesis that has been made in recent years for clean water production. The goal is to offer comprehensive and substantial contents in each chapter, entailing the electrospinning principle, novel materials and methods, properties, characterization, and applications, such as adsorption, catalysis, and membranes. The book is instrumental in terms of showing the scale-up production of desired fibers that ensure the control of the structure–properties relationship for developing effective water treatment technologies. Every chapter ends with a special section for highlighting research challenges and breakthroughs, so that scientists can explore these opportunities and discover new directions for future developments. Material scientists, nanotechnologists, chemists, engineers, water specialists, and environmentalists will be inspired by the information on electrospun nanofibrous materials to be found in the book. The wide variety of new ideas and recommended future reading will encourage early-career scientists working in this field to design new experiments and practices. The book is useful for college and university-level students enrolled in project courses in materials science and related fields.
Author : Radko Tiňo
Publisher : CRC Press
ISBN 13 : 1000342212
Total Pages : 153 pages
Book Rating : 4.0/5 (3 download)
Download or read book Plasma Technology in the Preservation and Cleaning of Cultural Heritage Objects written by Radko Tiňo and published by CRC Press. This book was released on 2021-02-19 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientists have long been looking for alternative methods for the cleaning of historical and cultural museum objects as conventional methods often fail to completely remove surface films, leaving contamination and surface residues behind. Low-temperature plasmas have recently been found to provide a new, efficient and durable approach that maintains the safety of both the materials and personnel. This book is the first to introduce the emerging use of low-temperature plasmas in the cleaning and decontamination of cultural heritage items. It provides a comprehensive exploration of the new possibilities of cleaning objects with plasma, before providing a practice guide to the individual cleaning methods and an overview of the technologies and conditions used in the different cleaning regimes. It is an ideal reference for researchers in plasma physics, in addition to professionals working in the field of historical and cultural conservation. Features: Provides a thorough overview of the cleaning potential of emerging plasma technologies in accessible language for professional restorers and conservators without a scientific background Includes the latest case studies from the field, which have not been published elsewhere yet Authored by a team of experts in the field
Author : Anil Kumar Saxena
Publisher : Springer Nature
ISBN 13 : 3030852814
Total Pages : 405 pages
Book Rating : 4.0/5 (38 download)
Download or read book Biophysical and Computational Tools in Drug Discovery written by Anil Kumar Saxena and published by Springer Nature. This book was released on 2021-10-18 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews recent physicochemical and biophysical techniques applied in drug discovery research, and it outlines the latest advances in computational drug design. Divided into 10 chapters, the book discusses about the role of structural biology in drug discovery, and offers useful application cases of several biophysical and computational methods, including time-resolved fluorometry (TRF) with Förster resonance energy transfer (FRET), X-Ray crystallography, nuclear magnetic resonance spectroscopy, mass spectroscopy, generative machine learning for inverse molecular design, quantum mechanics/molecular mechanics (QM/MM,ONIOM) and quantum molecular dynamics (QMT) methods. Particular attention is given to computational search techniques applied to peptide vaccines using novel mathematical descriptors and structure and ligand-based virtual screening techniques in drug discovery research. Given its scope, the book is a valuable resource for students, researchers and professionals from pharmaceutical industry interested in drug design and discovery.
