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Fundamental Toxicology For Chemists
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Book Synopsis Fundamental Toxicology for Chemists by : John Duffus
Download or read book Fundamental Toxicology for Chemists written by John Duffus and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a core introductory text to the subject of toxicology and the use of toxicological information for risk assessment by chemists. Increasingly, chemists are being required by law to advise on the safe handling of chemicals. Few chemists, however, have been trained in toxicology, and the subject is often not covered in a chemistry degree curriculum. It is to address this problem that this book has been written. Fundamental Toxicology for Chemists contains a proposed curriculum for teaching toxicology to chemists, which gives a firm grounding in the basics. With this book as a guide, lecturers will be able to design courses that cover all their students needs. In addition, students in all areas of chemistry will find it invaluable. Fundamental Toxicology for Chemists offers a unique assessment of the subject specifically for chemists. It is both comprehensible and fully comprehensive, covering developing areas such as reproduction, behavioural and ecological toxicology. The book has been approved by the IUPAC (International Union of Pure and Applied Chemists) committees on toxicology and the teaching of chemistry. It has a comprehensive index and an extensive glossary of terms, and will have lasting value to all chemists as a reference, and a text book.
Book Synopsis Fundamentals of Environmental Chemistry, Second Edition by : Stanley E. Manahan
Download or read book Fundamentals of Environmental Chemistry, Second Edition written by Stanley E. Manahan and published by CRC Press. This book was released on 2000-07-31 with total page 1024 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by a leader in the field, the Fundamentals of Environmental Chemistry, Second Edition puts the fundamentals of chemistry and environmental chemistry right at your students fingertips. Manahan presents the material in an understandable and interesting manner without being overly simplistic. They get basic coverage on: - Matter and the basis of its physical nature and behavior - Organic and biological chemistry - Chemistry of water, soil, and air - Industrial chemistry - Toxicological chemistry as it pertains to occupational health and human exposure to pollutants and toxicants - Energy, nuclear energy, and nuclear waste - Applications of nuclear science in areas such as tracing pesticide degradation and nuclear medicine - More than an introduction to this field, Fundamentals of Environmental Chemistry, Second Edition provides the foundation that gives your students an understanding of the chemical processes of the environment and the effects pollution on those processes.
Book Synopsis Fundamentals of Analytical Toxicology by : Robert J. Flanagan
Download or read book Fundamentals of Analytical Toxicology written by Robert J. Flanagan and published by John Wiley & Sons. This book was released on 2008-03-03 with total page 605 pages. Available in PDF, EPUB and Kindle. Book excerpt: The analytical toxicologist may be required to detect, identify, and in many cases measure a wide variety of compounds in samples from almost any part of the body or in related materials such as residues in syringes or in soil. This book gives principles and practical information on the analysis of drugs and poisons in biological specimens, particularly clinical and forensic specimens. After providing some background information the book covers aspects of sample collection, transport, storage and disposal, and sample preparation. Analytical techniques - colour tests and spectrophotometry, chromatography and electrophoresis, mass spectrometry, and immunoassay – are covered in depth, and a chapter is devoted to the analysis of trace elements and toxic metals. General aspects of method implementation/validation and laboratory operation are detailed, as is the role of the toxicology laboratory in validating and monitoring the performance of point of care testing (POCT) devices. The book concludes with reviews of xenobiotic absorption, distribution and metabolism, pharmacokinetics, and general aspects of the interpretation of analytical toxicology results. A clearly written, practical, integrated approach to the basics of analytical toxicology. Focuses on analytical, statistical and pharmacokinetic principles rather than detailed applications. Assumes only a basic knowledge of analytical chemistry. An accompanying website provides additional material and links to related sites. Written by an experienced team of authors,Fundamentals of Analytical Toxicology is an invaluable resource for those starting out in a career in analytical toxicology across a wide range of disciplines including clinical and forensic science, food safety, and pharmaceutical development. Praise from the reviews: “This is an ambitious effort to describe in detail the many and varied aspects of the science of toxicological analysis. The 17 chapters cover every foreseeable aspect, from specimen collection through analytical techniques and quality control to pharmacological principles and interpretation of results. The authors bring together a great deal of experience in the field and have succeeded admirably in achieving their goal: "to give principles and practical information on the analysis of drugs, poisons and other relevant analytes in biological specimens...". The book is very readable and quite up-to-date, and contains many illustrative figures, charts and tables. Both the student and the practicing professional would do well to study this material carefully, as there is something here for every conceivable level of interest.” Review from Randall Baselt "This text comes highly recommended for any analytical toxicology trainee." The Bulletin of the Royal College of Pathologists “Overall, this book provides a comprehensive, thorough, clear, up to date and practical treatment of analytical toxicology at a high standard. Understanding of the text is enhanced by the use of many illustrations. Specifications, guidelines, and methods are highlighted in grey background “Boxes”. The many and up to date literature references in each chapter demonstrate the authors’ thorough work and permit easy access to deeper information. Therefore this book can be highly recommended as a valuable source of knowledge in analytical toxicology both as an introduction and for the advanced reader.” GTFCh Bulletin “Toxichem + Krimtech”, May 2008 (translated, original review in German) “Many toxicologists will add this important reference to their libraries because it competently fills a need ...” International Journal of Toxicology “The book is very well illustrated, easy to understand and pleasant to read, and contains a wealth of dedicated information.” International Journal of Environmental Analytical Chemistry
Book Synopsis Fundamentals of Toxicology by : PK Gupta
Download or read book Fundamentals of Toxicology written by PK Gupta and published by Academic Press. This book was released on 2016-08-26 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Toxicology: Essential Concepts and Applications provides a crisp, easy-to-understand overview of the most important concepts, applications, and ideas needed to learn the basics of toxicology. Written by a pre-eminent toxicologist with over five decades of teaching experience, this comprehensive resource offers the hands-on knowledge needed for a strong foundation in the wide field of toxicology. Fundamentals of Toxicology includes a clear structure divided into five units to assist learning and understanding. The first unit provides extensive coverage on the background of toxicology including commonly used definitions and historical perspective, while following units cover: basic concepts; regulatory requirements and good laboratory practices, including types of toxicology testing and evaluation; toxic agents and adverse effects on health; and analytical, forensic, and diagnostic toxicology. This is an essential book for advanced students in toxicology and across the biomedical sciences, life sciences, and environmental sciences who want to learn the concepts of toxicology, as well as early researchers needing to refresh outside of their specialty. - Explains the essential concepts of toxicology in a clear fashion - Provides in-depth coverage of testing protocols, common drugs, chemicals, and laboratory-based diagnostic and analytical toxicology - Explores the history, foundations, and most recent concepts of toxicology - Serves as an essential reference for advanced students in toxicology and across the biomedical, life, and environmental sciences who want to learn the concepts of toxicology
Book Synopsis Environmental Chemistry and Toxicology of Mercury by : Guangliang Liu
Download or read book Environmental Chemistry and Toxicology of Mercury written by Guangliang Liu and published by John Wiley & Sons. This book was released on 2011-11-07 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the fundamentals, recent developments, and future research needs for critical mercury transformation and transport processes, as well as the experimental methods that have been employed in recent studies. The coverage discusses the environmental behavior and toxicological effects of mercury on organisms, including humans, and provides case studies at the end of each chapter. Bringing together information normally spread across several books, this text is unique in covering the entire mercury cycle and providing a baseline for what is known and what uncertainties remain in respect to mercury cycling.
Book Synopsis Fundamentals of Toxicologic Pathology by : Matthew A. Wallig
Download or read book Fundamentals of Toxicologic Pathology written by Matthew A. Wallig and published by Academic Press. This book was released on 2009-11-23 with total page 714 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicologic pathology integrates toxicology and the disciplines within it (such as biochemistry, pharmacodynamics and risk assessment) to pathology and its related disciplines (such as physiology, microbiology, immunology, and molecular biology). Fundamentals of Toxicologic Pathology Second Edition updates the information presented in the first edition, including five entirely new chapters addressing basic concepts in toxicologic pathology, along with color photomicrographs that show examples of specific toxicant-induced diseases in animals. The current edition also includes comparative information that will prove a valuable resource to practitioners, including diagnostic pathologists and toxicologists. - 25% brand new information, fully revised throughout - New chapters: Veterinary Diagnostic Toxicologic Pathology; Clinical Pathology; Nomenclature: Terminology for Morphologic Alterations; Techniques in Toxicologic Pathology - New color photomicrographs detailing specific toxicant-induced diseases in animals - Mechanistic information integrated from both toxicology and pathology discussing basic mechanisms of toxic injury and morphologic expression at the subcellular, cellular, and tissue levels
Book Synopsis Fundamentals of Environmental and Toxicological Chemistry by : Stanley E. Manahan
Download or read book Fundamentals of Environmental and Toxicological Chemistry written by Stanley E. Manahan and published by CRC Press. This book was released on 2013-02-25 with total page 617 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Environmental and Toxicological Chemistry: Sustainable Science, Fourth Edition covers university-level environmental chemistry, with toxicological chemistry integrated throughout the book. This new edition of a bestseller provides an updated text with an increased emphasis on sustainability and green chemistry. It is organized based on the five spheres of Earth’s environment: (1) the hydrosphere (water), (2) the atmosphere (air), (3) the geosphere (solid Earth), (4) the biosphere (life), and (5) the anthrosphere (the part of the environment made and used by humans). The first chapter defines environmental chemistry and each of the five environmental spheres. The second chapter presents the basics of toxicological chemistry and its relationship to environmental chemistry. Subsequent chapters are grouped by sphere, beginning with the hydrosphere and its environmental chemistry, water pollution, sustainability, and water as nature’s most renewable resource. Chapters then describe the atmosphere, its structure and importance for protecting life on Earth, air pollutants, and the sustainability of atmospheric quality. The author explains the nature of the geosphere and discusses soil for growing food as well as geosphere sustainability. He also describes the biosphere and its sustainability. The final sphere described is the anthrosphere. The text explains human influence on the environment, including climate, pollution in and by the anthrosphere, and means of sustaining this sphere. It also discusses renewable, nonpolluting energy and introduces workplace monitoring. For readers needing additional basic chemistry background, the book includes two chapters on general chemistry and organic chemistry. This updated edition includes three new chapters, new examples and figures, and many new homework problems.
Book Synopsis Fundamentals Of Aquatic Toxicology by : Gary M. Rand
Download or read book Fundamentals Of Aquatic Toxicology written by Gary M. Rand and published by CRC Press. This book was released on 2020-08-06 with total page 1152 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text is divided into three parts. The first part describes basic toxicological concepts and methodologies used in aquatic toxicity testing, including the philosophies underlying testing strategies now required to meet and support regulatory standards. The second part of the book discusses various factors that affect transport, transformation, ultimate distribution, and accumulation of chemicals in the aquatic environment, along with the use of modelling to predict fate.; The final section of the book reviews types of effects or endpoints evaluated in field studies and the use of structure-activity relationships in aquatic toxicology to predict biological activity and physio-chemical properties of a chemical. This section also contains an extensive background of environmental legislation in the USA and within the European Community, and an introduction to hazard/risk assessment with case studies.
Book Synopsis Casarett and Doull's Toxicology by : Curtis D. Klaassen
Download or read book Casarett and Doull's Toxicology written by Curtis D. Klaassen and published by McGraw-Hill Book Company Limited. This book was released on 1996 with total page 912 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated and revised edition delineates the basic concepts and fundamental principles needed to grasp current issues in modern toxicology. In addition, new contributions help to redefine the book's scope and coverage, and illuminate new and emerging areas of toxicologic interest.
Book Synopsis Toxicology and Risk Assessment by : Helmut Greim
Download or read book Toxicology and Risk Assessment written by Helmut Greim and published by John Wiley & Sons. This book was released on 2018-08-10 with total page 842 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a complete understanding of how our bodies respond to toxicants, and the principles used to assess the health risks of specific exposure scenarios Toxicology and Risk Assessment: A Comprehensive Introduction, Second Edition reflects recent advances in science and technology, and provides the scientific background and methodological issues to enable the reader to understand the basic principles in toxicology and to evaluate the health risks of specific exposure scenarios. Completely updated with the latest information, this book offers a concise introduction to the subject. It is divided into five sections: Principles in Toxicology, Organ Toxicology, Methods in Toxicology, Regulatory Toxicology, and Specific Toxicity. The 2nd Edition adds new chapters that cover recent scientific and technological advances and current topics including the endocrine system, alternatives to animal testing, risk assessment and thresholds for carcinogens, European and international regulation, nanomaterials, fuels, fragrances, and agrochemicals. Concentrates on the basic concepts of toxicology and provides sufficient information for the reader to become familiar with them in order to understand the principles and to evaluate the risks at given exposures 30% new chapters cover recent scientific and technological advances including alternatives to animal testing; genotoxic carcinogens; REACH regulations; nanomaterials; fuels; fragrances; PAHs; and agrochemicals Written by a team of international specialists, and edited by two outstanding scientists in the field Fully updated and expanded, Toxicology and Risk Assessment: A Comprehensive Introduction, Second Edition is an essential text for any student or researcher with an interest in toxicology and related risk assessments.
Book Synopsis Chemical Warfare Toxicology by : Franz Worek
Download or read book Chemical Warfare Toxicology written by Franz Worek and published by Royal Society of Chemistry. This book was released on 2016-05-04 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite ongoing efforts to prohibit the production, storage and use of chemical warfare agents recent world events highlight the enduring threat to the population from these agents. Research efforts in various countries have resulted in novel insights into chemical warfare toxicology that has enabled the development of new approaches for the diagnosis and treatment of chemical warfare poisoning. This book provides an up-to-date treatise on the ongoing research into the toxicology of chemical warfare agents, the diagnosis and verification of exposure, and the pre- and post-exposure treatment of poisoning. Focussing on the fundamentals of the toxicology of nerve agents and vesicants, this book will give the reader a comprehensive overview of the many different aspects of chemical warfare agent toxicology. The text will appeal to toxicologists, biochemists and weapons specialists working in industry and academia, and anyone with an interest in chemical warfare toxicology or exposure.
Book Synopsis Concepts in Toxicology by : John H Duffus
Download or read book Concepts in Toxicology written by John H Duffus and published by Royal Society of Chemistry. This book was released on 2009-10-01 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicology has never been more important. Advances in chemistry and technology offering improvements in the quality of human life become ever more rapid, bringing with them the potential for new toxicity hazards. This has led to legislation requiring toxicity testing and risk assessment for all chemicals and their uses. The new REACH (Risk Evaluation and Authorization of Chemicals) Regulation has profound economic consequences because, without official authorization, a chemical cannot be marketed. This book explains, in depth, the ideas underlying current advances in toxicology and its application in regulating and ensuring the safe use of chemicals. Sometimes old ideas have become assumptions that have become embedded in related laws and regulation, even though the thinking of toxicologists has moved on in line with developments in science. This leads to confusion in public understanding that the book should dispel. There are also fundamental ideas in toxicology that are not well understood concerning the concepts of hazard and risk and even about what constitutes a chemical. For many people the word 'chemical' describes manmade substances only. In fact, it is correctly applied to all substances that exist, from pure elements to the most complex biological molecules in food and medicines. This is further complicated by the complex distinction between the descriptors, 'toxic' and 'nontoxic'. Developments in epigenetics are revolutionizing our understanding of mutagenicity and carcinogenicity. Improved understanding of apoptosis and necrosis leads to improved interpretation of potentially toxic effects at the cellular level. The recently defined term 'chemical speciation' is driving more targeted research on the toxicity of inorganic chemicals. This book explains the concepts implied by key toxicological terms using diagrams to illustrate the relationships between them. It is an essential aid to understanding the new demands from regulators of risk assessment and to the implementation of appropriate risk management.
Book Synopsis Fundamental Toxicology by : John H Duffus
Download or read book Fundamental Toxicology written by John H Duffus and published by Royal Society of Chemistry. This book was released on 2015-11-09 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamental Toxicology is a concise and comprehensive review of toxicology. It is based on the highly successful Fundamental Toxicology for Chemists and has been enriched and expanded. Every chapter in this new edition has been revised and updated, and four new chapters have been added. With contributions from internationally recognised experts in their field, this broad-based introduction to the topic covers both well-established and rapidly developing areas of toxicology, such as toxicogenomics, reproductive toxicology, behavioural toxicology and ecotoxicology. The book was written and published with the support of the International Union of Pure and Applied Chemistry (IUPAC). The book includes new information on: risk assessment and risk management; toxicogenomics; effects of toxic substances on the human body; environmental distribution of chemicals and ecotoxicology; clinical toxicology; pharmaceutical toxicology; and aspects of laboratory measurement and safe laboratory practice. Fundamental Toxicology is ideal for students and includes extensive pedagogical features, such as an extensive glossary, a bibliography after each chapter and recommended further reading. It is also designed for teachers and lecturers, especially those who may be teaching toxicology for the first time. Included is a suggested curriculum for using the text to teach toxicology to students from various scientific disciplines. Professionals working in toxicology and related fields will find this an invaluable guide.
Book Synopsis Principles of Toxicology Testing, Second Edition by : Frank A Barile
Download or read book Principles of Toxicology Testing, Second Edition written by Frank A Barile and published by CRC Press. This book was released on 2013-04-02 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nationally, toxicology programs have evolved from a traditional exploration of the chemistry and applied toxicity of chemicals and drugs to a more comprehensive study of toxicology and toxicology testing as independent entities. Consequently, the second edition of Principles of Toxicology Testing starts with basic toxicological principles, including absorption, distribution, metabolism, and elimination of toxins, including chemicals and drugs. The book then continues with animal (in vivo) and in vitro toxicology testing methods associated with toxicological analysis and preclinical drug development. As in the first edition, the book begins with an introduction into the fundamentals of toxicology (Section I) to prepare readers for the subsequent topics and continues through with a discussion of toxicokinetics and human risk assessment. This introductory material is useful in understanding the applications of toxicology testing. Section II describes the fundamental principles of toxicology testing in animals in greater detail. This section describes acute toxicity studies as well as subchronic and chronic studies performed on animals. Special emphasis is placed on study design and determination of classical indicators for acute and chronic testing, such as the LD50. The book examines other short- and long-term animal toxicity testing methodologies, including dermal, ocular, and reproductive toxicity testing. In addition, mutagenicity and carcinogenicity studies are also discussed in separate chapters. Section III introduces and discusses in vitro alternatives to animal toxicology tests. This section emphasizes cell culture methodology and cellular methods for acute systemic toxicity, target organ toxicity, and local toxicity. The contributors present the advantages and disadvantages of alternative methods. They also describe the use of high-throughput screening and its applications, the concepts of standardization and validation of in vitro techniques (especially large, organized validation efforts currently supported by US and EU regulatory agencies), and the theories supporting the development of in vitro methodologies. This second edition is a must-read for undergraduate and graduate toxicology students. Industrial and academic research centers will also find the text useful for establishing a toxicology testing laboratory.
Author :United States. Public Health Service. Office of the Surgeon General Publisher : ISBN 13 : Total Pages :728 pages Book Rating :4.:/5 (318 download)
Book Synopsis How Tobacco Smoke Causes Disease by : United States. Public Health Service. Office of the Surgeon General
Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Book Synopsis Casarett & Doull's Essentials of Toxicology by : CURTIS. WATKINS KLAASSEN (JOHN.)
Download or read book Casarett & Doull's Essentials of Toxicology written by CURTIS. WATKINS KLAASSEN (JOHN.) and published by . This book was released on 2015-09-16 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis A Small Dose of Toxicology by : Steven G. Gilbert
Download or read book A Small Dose of Toxicology written by Steven G. Gilbert and published by CRC Press. This book was released on 2004-02-18 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: Everyday, we come into contact with many relatively harmless substances that could, at certain concentrations, be toxic. This applies not only to obvious candidates such as asbestos, lead, and gasoline, but also to compounds such as caffeine and headache tablets. While the field of toxicology has numerous texts devoted to aspects of biology, chemis
