Functionalized Mesoporous Silica Nanoparticles For Stimuli Responsive And Targeted Drug Delivery

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Stimuli-responsive Drug Delivery Systems

Author : Amit Singh
Publisher : Royal Society of Chemistry
ISBN 13 : 1788014669
Total Pages : 376 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Stimuli-responsive Drug Delivery Systems by : Amit Singh

Download or read book Stimuli-responsive Drug Delivery Systems written by Amit Singh and published by Royal Society of Chemistry. This book was released on 2018-07-09 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: The increased understanding of molecular aspects associated with chronic diseases, such as cancer and the role of tumor microenvironment, has led to the identification of endogenous and exogenous stimuli that can be exploited to devise “stimuli-responsive” materials for site-specific drug delivery applications. This book provides a comprehensive account on the design, materials chemistry, and application aspects behind these novel stimuli-responsive materials. Setting the scene, the editors open with a chapter addressing the need for smart materials in delivery applications for therapy, imaging and disease diagnosis. The following chapter describes the key physical and chemical aspects of smart materials, from lipids to polymers to hybrid materials, providing the reader with a springboard to delve into the more application oriented chapters that follow. With in-depth coverage of key drug delivery systems such as pH-responsive, temperature responsive, enzyme-responsive and light responsive systems, this book provides a rigorous foundation to the field. A perfect resource for graduate students and newcomers, the closing chapter on regulatory and commercialization challenges also makes the book ideal for those wanting to take the next step towards clinical translation.

Bioresponsive Polymers

Author : Deepa H. Patel
Publisher : CRC Press
ISBN 13 : 1000517594
Total Pages : 239 pages
Book Rating : 4.0/5 (5 download)

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Book Synopsis Bioresponsive Polymers by : Deepa H. Patel

Download or read book Bioresponsive Polymers written by Deepa H. Patel and published by CRC Press. This book was released on 2020-10-08 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume, Bioresponsive Polymers: Design and Application in Drug Delivery, focuses on recent advancements in bioresponsive polymers and their design, characterization, and applications in varied fields, such as drug delivery and gene delivery. It looks at several carriers for drug delivery and biological molecules using different bioresponsive polymers. To address the many difficulties in existing dosage forms, this book provides information on recent developments to overcome drawbacks of conventional forms of the drug delivery. The chapters cover most areas of bioresponsive polymers, starting with a basic introduction to bioresponsive polymers, followed by chapters on design, characterization, and mechanism of bioresponsive polymers; and applications of drug and gene delivery using bioresponsive polymers via oral, topical, nasal, ocular, and parenteral methods. The book also reviews recent advancements in bioresponsive polymers and advanced applications, such as engineering particulate moieties, biomedical applications, hydrogels as emerging therapy, and electrochemical responses, bioresponsive nanoparticles, and bioresponsive hydrogels.

Oral Lipid-Based Formulations

Author : David J. Hauss
Publisher : CRC Press
ISBN 13 : 1420017268
Total Pages : 370 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Oral Lipid-Based Formulations by : David J. Hauss

Download or read book Oral Lipid-Based Formulations written by David J. Hauss and published by CRC Press. This book was released on 2007-06-08 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oral lipid-based formulations are attracting considerable attention due to their capacity to facilitate gastrointestinal absorption and reduce or eliminate the effect of food on the absorption of poorly water-soluble, lipophilic drugs. Despite the obvious and demonstrated utility of these formulations for addressing a persistent and growing problem

Nanoengineering of Biomaterials

Author : Sougata Jana
Publisher : John Wiley & Sons
ISBN 13 : 3527349049
Total Pages : 1063 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Nanoengineering of Biomaterials by : Sougata Jana

Download or read book Nanoengineering of Biomaterials written by Sougata Jana and published by John Wiley & Sons. This book was released on 2022-04-18 with total page 1063 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive discussion of various types of nanoengineered biomaterials and their applications In Nanoengineering of Biomaterials: Drug Delivery & Biomedical Applications, an expert team of chemists delivers a succinct exploration of the synthesis, characterization, in-vitro and in-vivo drug molecule release, pharmacokinetic activity, pharmacodynamic activity, and the biomedical applications of several types of nanoengineered biomaterials. The editors have also included resources to highlight the most current developments in the field. The book is a collection of valuable and accessible reference sources for researchers in materials chemistry and related disciplines. It uses a functions-directed approach to using organic and inorganic source compounds that translate into biological systems as scaffolds, micelles, dendrimers, and other delivery systems. Nanoengineering of Biomaterials offers readers up-to-date chemistry and material science insights that are readily transferrable to biomedical systems. The book also includes: Thorough introductions to alginate nanoparticle delivery of therapeutics and chitosan-based nanomaterials in biological applications Comprehensive explorations of nanostructured carrageenan as a drug carrier, gellan gum nanoparticles in drug delivery, and guar-gum nanoparticles in the delivery of bioactive molecules Practical discussions of protein-based nanoparticles for drug delivery, solid lipid nanoparticles as drug carriers, and pH-responsive nanoparticles in therapy In-depth examinations of stimuli-responsive nano carriers in drug targeting Perfect for pharmaceutical chemists, materials scientists, polymer chemists, life scientists, and medicinal chemists, Nanoengineering of Biomaterials: Drug Delivery and Biomedical Applications is also an indispensable resource for biologists and bioengineers seeking a one-stop reference on the transferability of materials chemistry and nanotechnology to biomedicine.

Nanobiotechnology in Diagnosis, Drug Delivery and Treatment

Author : Mahendra Rai
Publisher : John Wiley & Sons
ISBN 13 : 1119671795
Total Pages : 416 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis Nanobiotechnology in Diagnosis, Drug Delivery and Treatment by : Mahendra Rai

Download or read book Nanobiotechnology in Diagnosis, Drug Delivery and Treatment written by Mahendra Rai and published by John Wiley & Sons. This book was released on 2020-11-10 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents nanobiotechnology in drug delivery and disease management Featuring contributions from noted experts in the field, this book highlights recent advances in the nano-based drug delivery systems. It also covers the diagnosis and role of various nanomaterials in the management of infectious diseases and non-infectious disorders, such as cancers and other malignancies and their role in future medicine. Nanobiotechnology in Diagnosis, Drug Delivery and Treatment starts by introducing how nanotechnology has revolutionized drug delivery, diagnosis, and treatments of diseases. It then focuses on the role of various nanocomposites in diagnosis, drug delivery, and treatment of diseases like cancer, Alzheimer's disease, diabetes, and many others. Next, it discusses the application of a variety of nanomaterials in the diagnosis and management of gastrointestinal tract disorders. The book explains the concept of nanotheranostics in detail and its role in effective monitoring of drug response, targeted drug delivery, enhanced drug accumulation in the target tissues, sustained as well as triggered release of drugs, and reduction in adverse effects. Other chapters cover aptamer-incorporated nanoparticle systems; magnetic nanoparticles; theranostics and vaccines; toxicological concerns of nanomaterials used in nanomedicine; and more. Provides a concise overview of state-of-the-art nanomaterials and their application like drug delivery in infectious diseases and non-infectious disorders Highlights recent advances in the nano-based drug delivery systems and role of various nanomaterials Introduces nano-based sensors which detect various pathogens Covers the use of nanodevices in diagnostics and theranostics Nanobiotechnology in Diagnosis, Drug Delivery and Treatment is an ideal book for researchers and scientists working in various disciplines such as microbiology, biotechnology, nanotechnology, pharmaceutical biotechnology, pharmacology, pharmaceutics, and nanomedicine.

Characterization of Pharmaceutical Nano- and Microsystems

Author : Leena Peltonen
Publisher : John Wiley & Sons
ISBN 13 : 1119414040
Total Pages : 410 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis Characterization of Pharmaceutical Nano- and Microsystems by : Leena Peltonen

Download or read book Characterization of Pharmaceutical Nano- and Microsystems written by Leena Peltonen and published by John Wiley & Sons. This book was released on 2020-12-21 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn about the analytical tools used to characterize particulate drug delivery systems with this comprehensive overview Edited by a leading expert in the field, Characterization of Pharmaceutical Nano- and Microsystems provides a complete description of the analytical techniques used to characterize particulate drug systems on the micro- and nanoscale. The book offers readers a full understanding of the basic physicochemical characteristics, material properties and differences between micro- and nanosystems. It explains how and why greater experience and more reliable measurement techniques are required as particle size shrinks, and the measured phenomena grow weaker. Characterization of Pharmaceutical Nano- and Microsystems deals with a wide variety of topics relevant to chemical and solid-state analysis of drug delivery systems, including drug release, permeation, cell interaction, and safety. It is a complete resource for those interested in the development and manufacture of new medicines, the drug development process, and the translation of those drugs into life-enriching and lifesaving medicines. Characterization of Pharmaceutical Nano- and Microsystems covers all of the following topics: An introduction to the analytical tools applied to determine particle size, morphology, and shape Common chemical approaches to drug system characterization A description of solid-state characterization of drug systems Drug release and permeation studies Toxicity and safety issues The interaction of drug particles with cells Perfect for pharmaceutical chemists and engineers, as well as all other industry professionals and researchers who deal with drug delivery systems on a regular basis, Characterization of Pharmaceutical Nano- and Microsystems also belongs on bookshelves of interested students and faculty who interact with this topic.

FASTtrack Pharmaceutics

Author : Yvonne Perrie
Publisher : Pharmaceutical Press
ISBN 13 : 0857110594
Total Pages : 257 pages
Book Rating : 4.8/5 (571 download)

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Book Synopsis FASTtrack Pharmaceutics by : Yvonne Perrie

Download or read book FASTtrack Pharmaceutics written by Yvonne Perrie and published by Pharmaceutical Press. This book was released on 2012 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Pharmaceutics - Drug delivery and targeting focuses on what pharmacy students really need to know in order to pass exams, providing concise, bulleted information, key points, tips and an all-important self-assessment section which includes MCQs."--Page 4 of cover.

Nanotechnology Characterization Tools for Tissue Engineering and Medical Therapy

Author : Challa S.S.R. Kumar
Publisher : Springer Nature
ISBN 13 : 3662595966
Total Pages : 467 pages
Book Rating : 4.6/5 (625 download)

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Book Synopsis Nanotechnology Characterization Tools for Tissue Engineering and Medical Therapy by : Challa S.S.R. Kumar

Download or read book Nanotechnology Characterization Tools for Tissue Engineering and Medical Therapy written by Challa S.S.R. Kumar and published by Springer Nature. This book was released on 2019-11-22 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ninth volume of a 40 volume series on nanoscience and nanotechnology, edited by the renowned scientist Challa S.S.R. Kumar. This handbook gives a comprehensive overview about Nanotechnology Characterization Tools for Tissue Engineering and Medical Therapy. Modern applications and state-of-the-art techniques are covered and make this volume an essential reading for research scientists in academia and industry.

Targeted Drug Delivery : Concepts and Design

Author : Padma V. Devarajan
Publisher : Springer
ISBN 13 : 3319113550
Total Pages : 788 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Targeted Drug Delivery : Concepts and Design by : Padma V. Devarajan

Download or read book Targeted Drug Delivery : Concepts and Design written by Padma V. Devarajan and published by Springer. This book was released on 2014-12-08 with total page 788 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative volume explores the fundamental concepts and numerous applications of targeted delivery of drugs to the body. This compilation has been divided into eight sections comprised of the basic principles of drug targeting, disease and organ/organelle-based targeting, passive and active targeting strategies, and various advanced drug delivery tools such as functionalized lipidic, polymeric and inorganic nanocarriers. Together, the twenty-three chapters cover a wide range of topics in the field, including tumor and hepatic targeting, polymer-drug conjugates, nanoemulsion, physical and biophysical characteristics of nanoparticles, and in vivo imaging techniques, among others. The book also examines advanced characterization techniques, regulatory hurdles and toxicity-related issues that are key features for successful commercialization of targeted drug delivery system products. Targeted Drug Delivery is a comprehensive reference guide for drug delivery researchers, both beginners and those already working in the field.

Nanotechnology for Bioapplications

Author : Bong-Hyun Jun
Publisher : Springer Nature
ISBN 13 : 9813361581
Total Pages : 293 pages
Book Rating : 4.8/5 (133 download)

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Book Synopsis Nanotechnology for Bioapplications by : Bong-Hyun Jun

Download or read book Nanotechnology for Bioapplications written by Bong-Hyun Jun and published by Springer Nature. This book was released on 2021-03-29 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book documents the tremendous progress in the use of nanotechnology for a range of bioapplications with the aim of providing students, researchers, technicians, and other professionals with an up-to-date overview of the field. After a general introduction to the surface modifications of nanoparticles required for different biological applications, and to the properties of the modified nanoparticles, a series of chapters describe the state of the art in respect of different types of nanoparticle, including silica nanoparticles, fluorescent nanomaterials, metal nanoparticles, magnetic nanoparticles, carbon-based nanostructures, and other novel nanomaterials. Detailed information is supplied on methods of preparation, chemical and physical properties, and current and potential applications. The closing chapters discuss lithography methods for the top-down approach to nanoparticle synthesis and the use of spectroscopic studies as a tool for the characterization of each nanoparticle. Future prospects and challenges for the development of further nanomaterials with bioapplications are also covered.

Nanostructures for Cancer Therapy

Author : Alexandru Mihai Grumezescu
Publisher : Elsevier
ISBN 13 : 0323461506
Total Pages : 922 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Nanostructures for Cancer Therapy by : Alexandru Mihai Grumezescu

Download or read book Nanostructures for Cancer Therapy written by Alexandru Mihai Grumezescu and published by Elsevier. This book was released on 2017-04-11 with total page 922 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanostructures for Cancer Therapy discusses the available preclinical and clinical nanoparticle technology platforms and their impact on cancer therapy, including current trends and developments in the use of nanostructured materials in chemotherapy and chemotherapeutics. In particular, coverage is given to the applications of gold nanoparticles and quantum dots in cancer therapies. In addition to the multifunctional nanomaterials involved in the treatment of cancer, other topics covered include nanocomposites that can target tumoral cells and the release of antitumoral therapeutic agents. The book is an up-to-date overview that covers the inorganic and organic nanostructures involved in the diagnostics and treatment of cancer. - Provides an examination of nanoparticle delivery systems for cancer treatment, illustrating how the use of nanotechnology can help provide more effective chemotherapeutic treatments - Examines, in detail, the different types of nanomaterials used in cancer therapy, also explaining the effect of each - Provides a cogent overview of recent developments in the use of nanostructured materials in chemotherapeutics, allowing readers to quickly familiarize themselves with this area

Mesoporous Silica-based Nanomaterials and Biomedical Applications - Part A

Author :
Publisher : Academic Press
ISBN 13 : 9780128151129
Total Pages : 0 pages
Book Rating : 4.1/5 (511 download)

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Book Synopsis Mesoporous Silica-based Nanomaterials and Biomedical Applications - Part A by :

Download or read book Mesoporous Silica-based Nanomaterials and Biomedical Applications - Part A written by and published by Academic Press. This book was released on 2018-09-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer Therapy and Diagnosis, Part A, Volume 43 in The Enzymes series, highlights new advances in the field, with this new volume presenting interesting chapters on Mesoporous silica nanoparticle synthesis, Periodic mesoporous organosilica, Nanovalves and other nanomachine-equipped nanoparticles and controlled release, Two-photon light control and photodynamic therapy, Biodegradable PMO nanoparticles, Cationic mesoporous silica and protein delivery, Drug loading, stimuli-responsive delivery and cancer treatment, Animal models and cancer therapy, siRNA delivery and TWIST shutdown for ovarian cancer treatment, and TBC (mesoporous silica nanoparticles and cancer therapy or biodistribution of MSN).

Nanopharmaceutical Advanced Delivery Systems

Author : Vivek Dave
Publisher : John Wiley & Sons
ISBN 13 : 1119711681
Total Pages : 467 pages
Book Rating : 4.1/5 (197 download)

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Book Synopsis Nanopharmaceutical Advanced Delivery Systems by : Vivek Dave

Download or read book Nanopharmaceutical Advanced Delivery Systems written by Vivek Dave and published by John Wiley & Sons. This book was released on 2020-12-29 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides a single volume covering detailed descriptions about various delivery systems, their principles and how these are put in use for the treatment of multiple diseases. It is divided into four sections where the first section deals with the introduction and importance of novel drug delivery system. The second section deals with the most advanced drug delivery systems like microbubbles, dendrimers, lipid-based nanoparticles, nanofibers, microemulsions etc., describing the major principles and techniques of the preparations of the drug delivery systems. The third section elaborates on the treatments of diverse diseases like cancer, topical diseases, tuberculosis etc. The fourth and final section provides a brief informative description about the regulatory aspects of novel drug delivery system that is followed in various countries.

Smart Nanovesicles for Drug Targeting and Delivery

Author : Maria Carafa
Publisher : MDPI
ISBN 13 : 3038978949
Total Pages : 198 pages
Book Rating : 4.0/5 (389 download)

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Book Synopsis Smart Nanovesicles for Drug Targeting and Delivery by : Maria Carafa

Download or read book Smart Nanovesicles for Drug Targeting and Delivery written by Maria Carafa and published by MDPI. This book was released on 2019-05-20 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: We can use the short text on the SI page for the description, or you make slight modifications on it. The description/summary is only for promotion (flyer, distribution channels), and will not be included in the book You can use the short text on the SI page for the description Nanovesicles are highly-promising systems for the delivery and/or targeting of drugs, biomolecules and contrast agents. Despite the fact that initial studies in this area were performed on phospholipid vesicles, there is an ever-increasing interest in the use of other molecules to obtain smart vesicular carriers focusing on strategies for targeted delivery. These systems can be obtained using newly synthesized smart molecules, or by intelligent design of opportune carriers to achieve specific delivery to the site of action. The drug/contrast agent-containing vesicles need to be directed to precise locations within the body to obtain desired magnitude and duration of the therapeutic or diagnostic effect. This spatial control in the delivery might open new avenues to modulate drug activity while avoiding side-effects and to optimize contrast agent properties while avoiding a broad distribution in the organism. However, delivering and targeting active substances into specific tissues and cells is still a challenge in designing novel therapeutic approaches against untreatable disorders, such as tumors and degenerative diseases.

Bio-inorganic Hybrid Nanomaterials

Author : Eduardo Ruiz-Hitzky
Publisher : John Wiley & Sons
ISBN 13 : 3527621458
Total Pages : 521 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Bio-inorganic Hybrid Nanomaterials by : Eduardo Ruiz-Hitzky

Download or read book Bio-inorganic Hybrid Nanomaterials written by Eduardo Ruiz-Hitzky and published by John Wiley & Sons. This book was released on 2008-06-25 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: This ready reference is the first to collate the interdisciplinary knowledge from materials science, bioengineering and nanotechnology to give an in-depth overview of the topic. As such, it provides broad coverage of combinations between inorganic materials and such key biological structures as proteins, enzymes, DNA, or biopolymers. With its treatment of various application directions, including bioelectronic interfacing, tissue repair, porous membranes, sensors, nanocontainers, and DNA engineering, this is essential reading for materials engineers, medical researchers, catalytic chemists, biologists, and those working in the biotechnological and semiconductor industries.

Polymer Brushes

Author : Rigoberto C. Advincula
Publisher : Wiley-VCH
ISBN 13 : 9783527310333
Total Pages : 501 pages
Book Rating : 4.3/5 (13 download)

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Book Synopsis Polymer Brushes by : Rigoberto C. Advincula

Download or read book Polymer Brushes written by Rigoberto C. Advincula and published by Wiley-VCH. This book was released on 2004-09-03 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: Materials scientists, polymer chemists, surface physicists and materials engineers will find this book a complete and detailed treatise on the field of polymer brushes, their synthesis, characterization and manifold applications. In a first section, the various synthetic pathways and different surface materials are introduced and explained, followed by a second section covering important aspects of characterization and analysis in both flat surfaces and particles. These specific surface initiated polymerization (SIP) systems such as linear polymers, homopolymers, block copolymers, and hyperbranched polymers are unique compared to previously reported systems by chemisorption or physisorption. They have found their way in both large-scale and miniature applications of polymer brushes, which is covered in the last section. Such 'hairy' surfaces offer fascinating opportunities for addressing numerous problems of both academic and, in particular, industrial interest: high-quality, functional or protective coatings, composite materials, surface engineered particles, metal-organic interfaces, biological applications, micro-patterning, colloids, nanoparticles, functional devices, and many more. It is the desire of the authors that this book will be of benefit to readers who want to "brush-up on polymers".

Nanotechnologies in Food and Agriculture

Author : Mahendra Rai
Publisher : Springer
ISBN 13 : 3319140248
Total Pages : 352 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Nanotechnologies in Food and Agriculture by : Mahendra Rai

Download or read book Nanotechnologies in Food and Agriculture written by Mahendra Rai and published by Springer. This book was released on 2015-03-31 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a comprehensive overview of new and emerging nanotechnologies. It includes aspects of nanoparticle monitoring, toxicity, and public perception, and covers applications that address both crop growing and treatment of agricultural wastewater. Topics include nanoagrochemicals (nanofertilizers, -pesticides, -herbicides), nanobiosensors, and nanotechnologies for food processing, packaging, and storage, crop improvement and plant disease control. The group of expert authors is led by an experienced team of editors.