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Functional Role Of Inducible Bronchus Associated Lymphoid Tissue Ibalt In Allergic Airway Inflammation
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Book Synopsis Crossroads between Innate and Adaptive Immunity by : Peter D. Katsikis
Download or read book Crossroads between Innate and Adaptive Immunity written by Peter D. Katsikis and published by Springer Science & Business Media. This book was released on 2007-12-08 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: This compilation presents mini-reviews derived from work presented at the Aegean Conference: "First Crossroads between Innate and Adaptive Immunity," which occurred in October, 2005 at the Hilton Conference Center on the island of Rhodes, Greece. The conference included sessions dedicated to host recognition of and response to pathogens, innate immune networks, antigen presentation, and adaptive immune responses, each headlined by a leading scientist.
Book Synopsis Mucosal T Cells by : Thomas T. MacDonald
Download or read book Mucosal T Cells written by Thomas T. MacDonald and published by S Karger Ag. This book was released on 1998 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are more T cells in the gastrointestinal tract and lung than in the rest of the body combined. The aim of this book is to cover all the important aspects of the biology of these cells in animals and in man. Basic observations are described as well as disease states where aberrant activation of mucosal T cells causes tissue damage. The continuing discovery of features of mucosal T cells which make them different from T cells in the periphery is a consistent theme throughout the text. Topics discussed include new developments in understanding why the characteristic response of mucosal T cells to soluble antigens is tolerance, the role of the gut epithelium in intestinal immunity, the molecular basis by which T cells home to the gut mucosa, the functions of gammadelta T cells, the discovery of a new lymphoid organ - the cryptopatch - in the mouse gut, and the remarkable oligoclonality of the alphabeta and gammadelta T cells in the gut epithelium. In more disease-related sections, the way in which T cells play a role in asthma and protection from parasite infection, and how they cause inflammatory bowel disease in man and animals are described. Providing an excellent survey of the field, this book is a valuable resource for both basic scientists and clinicians interested in intestinal immunology and gastrointestinal disease.
Book Synopsis Transcriptional and Chromatin Regulation in Adaptive and Innate Immune Cells by : Keiko Ozato
Download or read book Transcriptional and Chromatin Regulation in Adaptive and Innate Immune Cells written by Keiko Ozato and published by Frontiers Media SA. This book was released on 2020-05-22 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transcription depends on an ordered sequence of events, starting with (i) setting of the enhancer and chromatin environment, (ii) assembly of DNA binding and general transcription factors, (iii) initiation, elongation, processing of mRNA and termination, followed by (iv) creation of epigenetic marks and memory formation. Highlighting the importance of these activities, more than 10% total genes are dedicated to regulating transcriptional mechanisms. This area of research is highly active and new insights are continuously being added to our knowledge. Cells of the immune system have unique features of gene regulation to support diverse tasks required for innate and adaptive immunity. Innate immunity involves the recognition of external infectious and noxious agents as well as internal cancer cell components, and the elimination of these agents by non-specific mechanisms. Adaptive immunity involves gene rearrangement to achieve highly specific T and B cell responses, imparting the capability of self and non-self discrimination. This requires transcription and epigenetic regulation. Adaptive immunity also employs epigenetic memory, enabling recapitulation of prior transcription. Recent advances in nuclear architecture, chromatin structure, and transcriptional regulation have provided new insights into immune responses. The increased understanding of these molecular mechanisms is now affording opportunities to improve therapeutic strategies for various diseases.
Book Synopsis Regulation of Immunity by Non-Immune Cells by : Kenji Kabashima
Download or read book Regulation of Immunity by Non-Immune Cells written by Kenji Kabashima and published by Frontiers Media SA. This book was released on 2021-11-08 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Inducible Lymphoid Organs by : Kenji Kabashima
Download or read book Inducible Lymphoid Organs written by Kenji Kabashima and published by Springer Nature. This book was released on 2020-08-17 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book sheds new light on “inducible” lymphoid organs (ILOs): antigen presentation sites that are generated de novo in peripheral tissues under various pathogenic conditions. Accomplished immunologists demonstrate that the physiological role of these ILOs is completely different from that of central lymphoid organs, i.e., the lymph nodes or spleen. In addition to the central organs, the ILOs are considered essential structures for the efficient elicitation of adaptive immune responses in lesions. The respective chapters highlight examples from multiple sites, e.g. the skin, lung, intestinal tract, genital tract, the synovial membrane of the joints and artificial lymph nodes. Accordingly, readers will learn that ILO structure and function can vary substantially, depending on the context. Presenting the results of the latest immunological research, the book offers a fascinating and insightful read for both scientists and clinicians in the areas of infectious and immune-associated diseases.
Book Synopsis Mucosal Immunology of Acute Bacterial Pneumonia by : Alice Prince
Download or read book Mucosal Immunology of Acute Bacterial Pneumonia written by Alice Prince and published by Springer Science & Business Media. This book was released on 2012-12-09 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: In contrast to the substantial literature that focuses upon innate immune signaling in the gut, there is remarkably less known about the response of the airway to bacterial pathogens. The purpose of this book will be to review the current status of theunderstanding of the pathogenesis of acute bacterial pneumonia, slanted toward the mucosal immunology of these infections. It will describe, in general, the signaling cascades that control the proinflammatory response to bacterial infection in the lung. How innate immune signaling is orchestrated in response to specific common airway pathogens is addressed, targeting Staphylococus aureus (including MRSA), Streptococcus pneumoniae and Klebsiella pneumoniae. By describing the general immunological responses to conserved bacterial components and then detailing how specific organisms cause infection, this book provides a targeted but comprehensive review of this important topic.
Book Synopsis Jewish Families in Europe, 1939-Present by : Joanna Beata Michlic
Download or read book Jewish Families in Europe, 1939-Present written by Joanna Beata Michlic and published by Brandeis University Press. This book was released on 2017-01-03 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers an extensive introduction and 13 diverse essays on how World War II, the Holocaust, and their aftermath affected Jewish families and Jewish communities, with an especially close look at the roles played by women, youth, and children. Focusing on Eastern and Central Europe, themes explored include: how Jewish parents handled the Nazi threat; rescue and resistance within the Jewish family unit; the transformation of gender roles under duress; youth's wartime and early postwar experiences; postwar reconstruction of the Jewish family; rehabilitation of Jewish children and youth; and the role of Zionism in shaping the present and future of young survivors. Relying on newly available archival material and novel research in the areas of families, youth, rescue, resistance, gender, and memory, this volume will be an indispensable guide to current work on the familial and social history of the Holocaust.
Book Synopsis Paul's Fundamental Immunology by : Martin Flajnik
Download or read book Paul's Fundamental Immunology written by Martin Flajnik and published by Lippincott Williams & Wilkins. This book was released on 2022-07-19 with total page 3597 pages. Available in PDF, EPUB and Kindle. Book excerpt: Selected as a Doody's Core Title for 2022! Defining the field of immunology for 40 years, Paul’s Fundamental Immunology continues to provide detailed, authoritative, up-to-date information that uniquely bridges the gap between basic immunology and the disease process. The fully revised 8th edition maintains the excellence established by Dr. William E. Paul, who passed away in 2015, and is now under new editorial leadership of Drs. Martin F. Flajnik, Nevil J. Singh, and Steven M. Holland. It’s an ideal reference and gold standard text for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role.
Book Synopsis Spencer's Pathology of the Lung by : Philip Hasleton
Download or read book Spencer's Pathology of the Lung written by Philip Hasleton and published by Cambridge University Press. This book was released on 2013-01-17 with total page 4616 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully rewritten and updated for the cutting-edge sixth edition, Spencer's Pathology of the Lung follows in its predecessors' footsteps as the gold-standard textbook of pulmonary diseases. All recognized diseases of the lungs are discussed and illustrated with extensive, high-quality color images. Each chapter includes practical, clear and concise diagnostic features, including immunohistochemistry, molecular tests and differential diagnoses, while rare entities are discussed and illustrated in detail. This thoroughly reworked edition includes new classification schemes and the latest understanding of the pathophysiology and molecular aspects of a wide range of diseases. Non-neoplastic diseases are presented according to epidemiology, genetics, clinical manifestations, radiographic findings, pathology, cytology, laboratory findings, pathogenesis, differential diagnosis, prognosis and natural history. Neoplasms are discussed according to cell or origin with sections devoted to genetics, molecular findings and clinicopathologic correlations. Downloadable versions of all images are available on a CD-ROM packaged with the print book. Written and edited by leading experts in the field, this is an essential resource for practising and trainee pathologists.
Book Synopsis Veterinary Anatomy and Physiology by :
Download or read book Veterinary Anatomy and Physiology written by and published by BoD – Books on Demand. This book was released on 2019-03-13 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: Knowledge of veterinary anatomy and physiology is essential for veterinary professionals and researchers. The chapters reflect the diverse and dynamic research being undertaken in a variety of different species throughout the world. Whether the animals have roles in food security, agriculture, or as companion, wild, or working animals, the lessons we learn impact on many areas of the profession. This book highlights research ranging from the cardiovascular and musculoskeletal systems, prostate and hoof, through to histopathology, imaging, and molecular techniques. It investigates both healthy and pathological conditions at differing stages of life. The importance of each cell and tissue through to the whole organism is explored alongside the methodologies used to understand these vital structures and functions.
Download or read book Advances in Immunology written by and published by Academic Press. This book was released on 2010-11-26 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future. - Contributions from leading authorities and industry experts - Informs and updates on all the latest developments in the field
Book Synopsis Tertiary Lymphoid Structures by : Marie-Caroline Dieu-Nosjean
Download or read book Tertiary Lymphoid Structures written by Marie-Caroline Dieu-Nosjean and published by Humana Press. This book was released on 2018-09-05 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores the various methods used to study tertiary lymphoid structures (TLS) in pathological situations. Pre-clinical models are also discussed in detail to show how TLS structure, development, and maintenance can be targeted and studied in vivo. The chapters in this book cover topics such as humans and mice; strategies to quantify TLS in order to use it in stained tissue sections; classifying a gene signature form fixed and paraffin-embedded tissues; and development of murine inflammatory models to help look at TLS in the context of infection or malignancy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, Tertiary Lymphoid Structures: Methods and Protocols is a valuable resource that increases the reader’s knowledge on immune functions and how they will pave the way to future therapeutic applications.
Book Synopsis Autoimmunity and Chronic Inflammation in Early Life by : Ravi Misra
Download or read book Autoimmunity and Chronic Inflammation in Early Life written by Ravi Misra and published by Frontiers Media SA. This book was released on 2021-10-29 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Immunoregulation at Mucosal Surfaces by : Javier Leceta
Download or read book Immunoregulation at Mucosal Surfaces written by Javier Leceta and published by Frontiers Media SA. This book was released on 2022-09-21 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Allergy and Immunotoxicology in Occupational Health - The Next Step by : Takemi Otsuki
Download or read book Allergy and Immunotoxicology in Occupational Health - The Next Step written by Takemi Otsuki and published by Springer Nature. This book was released on 2020-06-23 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a collection of the latest clinical and research findings in the field of allergy and immunotoxicology, covering the allergic responses to various nanoparticles and nanomaterials, posttreatment immune reconstruction, and monitoring the workplace environment. Following on from its acclaimed predecessor, the book provides readers with novel insights into immune effects, autoimmune diseases, and the immunotoxicity of various substances, such as silica and asbestos. Allergy and Immunotoxicology in Occupational Health - The Next Step invites readers in the occupational health sector to reflect on critical yet unresolved questions, and provides a foundation for future research on the health impairments resulting from environmental and occupational exposure to these substances.
Book Synopsis Mucosal Immune Defense: Immunoglobulin A by : Charlotte S. Kaetzel
Download or read book Mucosal Immune Defense: Immunoglobulin A written by Charlotte S. Kaetzel and published by Springer Science & Business Media. This book was released on 2007-10-04 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: This key work in the field draws on a broad spectrum of molecular biologic, biochemical, and immunogenetic approaches in combination with human and murine in vitro cell culture and in vivo model systems to address questions in mucosal immunity. Humans produce more immunoglobulin A (IgA) than all other antibody isotypes combined. This book is designed to serve as a concise reference of the present knowledge of the biology of IgA.
Book Synopsis Mucosal Immunology by : Jiri Mestecky
Download or read book Mucosal Immunology written by Jiri Mestecky and published by Academic Press. This book was released on 2015-03-06 with total page 2566 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mucosal Immunology, now in its fourth edition, is the only comprehensive reference covering the basic science and clinical manifestations of mucosal immunology. Most infectious agents enter the body through the various mucous membranes, and many common infections take place in or on mucous membranes, making this subject an area of singular importance in the field of immunology. This book contains new research data, exceptional illustrations, original theory, a new perspective, and excellent organization. It covers immune system topics, such as inductive and effector tissues and cells, and development and physiology of the mucosal barrier; diseases in the digestive system, respiratory tract, and genitourinary tract; and immunodeficiency. - The most comprehensive text on mucosal immunology from internationally recognized experts in the field - Includes exceptional color illustrations, new research data, original theory and information on all mucosal diseases - Contains nine new chapters and an expanded appendix
