Function and Evolution of Repeated DNA Sequences

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Publisher : John Wiley & Sons
ISBN 13 : 1394264895
Total Pages : 404 pages
Book Rating : 4.3/5 (942 download)

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Book Synopsis Function and Evolution of Repeated DNA Sequences by : Guy-Franck Richard

Download or read book Function and Evolution of Repeated DNA Sequences written by Guy-Franck Richard and published by John Wiley & Sons. This book was released on 2023-12-27 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: The genome of a living being is composed of DNA sequences with diverse origins. Beyond single-copy genes, whose product has a biological function that can be inferred by experimentation, certain DNA sequences, present in a large number of copies, escape the most refined approaches aimed at elucidating their precise role. The existence of what 20th century geneticists had already perceived (and wrongly described as "junk DNA"!) was confirmed by the sequencing of the first complex genomes, including that of Homo sapiens. A large part of what defines a living thing is not unique, but repeated, sometimes a very large number of times, increasing in complexity with successive duplications and multiplication. Understanding and defining the many functions of this myriad of repeated sequences, as well as their evolution through natural selection, has become one of the major challenges for 21st century genomics.

Function and Evolution of Repeated DNA Sequences

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1789451191
Total Pages : 404 pages
Book Rating : 4.7/5 (894 download)

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Book Synopsis Function and Evolution of Repeated DNA Sequences by : Guy-Franck Richard

Download or read book Function and Evolution of Repeated DNA Sequences written by Guy-Franck Richard and published by John Wiley & Sons. This book was released on 2024-02-13 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: The genome of a living being is composed of DNA sequences with diverse origins. Beyond single-copy genes, whose product has a biological function that can be inferred by experimentation, certain DNA sequences, present in a large number of copies, escape the most refined approaches aimed at elucidating their precise role. The existence of what 20th century geneticists had already perceived (and wrongly described as "junk DNA"!) was confirmed by the sequencing of the first complex genomes, including that of Homo sapiens. A large part of what defines a living thing is not unique, but repeated, sometimes a very large number of times, increasing in complexity with successive duplications and multiplication. Understanding and defining the many functions of this myriad of repeated sequences, as well as their evolution through natural selection, has become one of the major challenges for 21st century genomics.

Repetitive DNA Sequences

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Author :
Publisher : MDPI
ISBN 13 : 3039283669
Total Pages : 206 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Repetitive DNA Sequences by : Andrew G. Clark

Download or read book Repetitive DNA Sequences written by Andrew G. Clark and published by MDPI. This book was released on 2020-03-05 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Repetitive DNA is ubiquitous in eukaryotic genomes, and, in many species, comprises the bulk of the genome. Repeats include transposable elements that can self-mobilize and disperse around the genome, and tandemly-repeated satellite DNAs that increase in copy number due to replication slippage and unequal crossing over. Despite their abundance, repetitive DNA is often ignored in genomic studies due to technical challenges in their identification, assembly, and quantification. New technologies and methods are now providing the unprecedented power to analyze repetitive DNAs across diverse taxa. Repetitive DNA is of particular interest because it can represent distinct modes of genome evolution. Some repetitive DNA forms essential genome structures, such as telomeres and centromeres, which are required for proper chromosome maintenance and segregation, whereas others form piRNA clusters that regulate transposable elements; thus, these elements are expected to evolve under purifying selection. In contrast, other repeats evolve selfishly and produce genetic conflicts with their host species that drive adaptive evolution of host defense systems. However, the majority of repeats likely accumulate in eukaryotes in the absence of selection due to mechanisms of transposition and unequal crossing over. Even these neutral repeats may indirectly influence genome evolution as they reach high abundance. In this Special Issue, the contributing authors explore these questions from a range of perspectives.

Repetitive DNA

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Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318021490
Total Pages : 239 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Repetitive DNA by : Manuel A. Garrido-Ramos

Download or read book Repetitive DNA written by Manuel A. Garrido-Ramos and published by Karger Medical and Scientific Publishers. This book was released on 2012 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: The experimental data that have been generated using new molecular techniques associated with the completion of genome projects have changed our perception of the structural features, functional implications and evolutionary dynamics of repetitive DNA sequences. This volume of Genome Dynamics provides a valuable update on recent developments in research into multigene families, centromeres, telomeres, microsatellite DNA, satellite DNA, and transposable elements. Each chapter presents a review by distinguished experts and analyzes repetitive DNA diversity and abundance, as well as the impact on genome structure, function and evolution. This publication is targeted at scientists and scholars at every level, from students to faculty members, and, indeed, anyone involved or interested in genetics, molecular evolution, molecular biology as well as genomics will find it a valuable source of up-to-date information.

The Evolution of Repeated DNA Sequences in Primates

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Publisher :
ISBN 13 :
Total Pages : 336 pages
Book Rating : 4.:/5 (16 download)

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Book Synopsis The Evolution of Repeated DNA Sequences in Primates by : Gary Michael Fox

Download or read book The Evolution of Repeated DNA Sequences in Primates written by Gary Michael Fox and published by . This book was released on 1983 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Evolution of a Repeated DNA Sequence Can be Used to Classify O̲n̲c̲h̲o̲c̲e̲r̲c̲a̲

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Publisher :
ISBN 13 :
Total Pages : 374 pages
Book Rating : 4.:/5 (265 download)

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Book Synopsis The Evolution of a Repeated DNA Sequence Can be Used to Classify O̲n̲c̲h̲o̲c̲e̲r̲c̲a̲ by : Peter Allen Zimmerman

Download or read book The Evolution of a Repeated DNA Sequence Can be Used to Classify O̲n̲c̲h̲o̲c̲e̲r̲c̲a̲ written by Peter Allen Zimmerman and published by . This book was released on 1992 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Plant Science, 2 Volume Set

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Publisher : John Wiley & Sons
ISBN 13 : 0470057238
Total Pages : 1697 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Handbook of Plant Science, 2 Volume Set by : Keith Roberts

Download or read book Handbook of Plant Science, 2 Volume Set written by Keith Roberts and published by John Wiley & Sons. This book was released on 2007-12-10 with total page 1697 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant Science, like the biological sciences in general, has undergone seismic shifts in the last thirty or so years. Of course science is always changing and metamorphosing, but these shifts have meant that modern plant science has moved away from its previous more agricultural and botanical context, to become a core biological discipline in its own right. However the sheer amount of information that is accumulating about plant science, and the difficulty of grasping it all, understanding it and evaluating it intelligently, has never been harder for the new generation of plant scientists or, for that matter, established scientists. And that is precisely why this Handbook of Plant Science has been put together. Discover modern, molecular plant sciences as they link traditional disciplines! Derived from the acclaimed Encyclopedia of Life Sciences! Thorough reference of up-to-the minute, reliable, self-contained, peer-reviewed articles – cross-referenced throughout! Contains 255 articles and 48 full-colour pages, written by top scientists in each field! The Handbook of Plant Science is an authoritative source of up-to-date, practical information for all teachers, students and researchers working in the field of plant science, botany, plant biotechnology, agriculture and horticulture.

Advanced Genetics

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Publisher : CRC Press
ISBN 13 : 9781439892930
Total Pages : 696 pages
Book Rating : 4.8/5 (929 download)

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Book Synopsis Advanced Genetics by : Gurbachan S. Miglani

Download or read book Advanced Genetics written by Gurbachan S. Miglani and published by CRC Press. This book was released on 2002-08-26 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt: An advanced level volume for postgraduate students and researchers of genetics, cytogenetics biotechnology, biosciences, botany, and zoology which provides detailed coverage of mendelian, molecular, biochemical, immuno, human, mutagenesis, and evolutionary genetics. Concepts, principles and phenomena of genetics have been explained with the help of tables and figures including references, questions and numerical problems at the end of each chapter.

DNA Repair and Mutagenesis

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Author :
Publisher : American Society for Microbiology Press
ISBN 13 : 1555813194
Total Pages : 2587 pages
Book Rating : 4.5/5 (558 download)

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Book Synopsis DNA Repair and Mutagenesis by : Errol C. Friedberg

Download or read book DNA Repair and Mutagenesis written by Errol C. Friedberg and published by American Society for Microbiology Press. This book was released on 2005-11-22 with total page 2587 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential resource for all scientists researching cellular responses to DNA damage. • Introduces important new material reflective of the major changes and developments that have occurred in the field over the last decade. • Discussed the field within a strong historical framework, and all aspects of biological responses to DNA damage are detailed. • Provides information on covering sources and consequences of DNA damage; correcting altered bases in DNA: DNA repair; DNA damage tolerance and mutagenesis; regulatory responses to DNA damage in eukaryotes; and disease states associated with defective biological responses to DNA damage.

Repetitive DNA Sequences

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Publisher :
ISBN 13 : 9783039283675
Total Pages : 206 pages
Book Rating : 4.2/5 (836 download)

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Book Synopsis Repetitive DNA Sequences by : Andrew G. Clark

Download or read book Repetitive DNA Sequences written by Andrew G. Clark and published by . This book was released on 2020 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Repetitive DNA is ubiquitous in eukaryotic genomes, and, in many species, comprises the bulk of the genome. Repeats include transposable elements that can self-mobilize and disperse around the genome, and tandemly-repeated satellite DNAs that increase in copy number due to replication slippage and unequal crossing over. Despite their abundance, repetitive DNA is often ignored in genomic studies due to technical challenges in their identification, assembly, and quantification. New technologies and methods are now providing the unprecedented power to analyze repetitive DNAs across diverse taxa. Repetitive DNA is of particular interest because it can represent distinct modes of genome evolution. Some repetitive DNA forms essential genome structures, such as telomeres and centromeres, which are required for proper chromosome maintenance and segregation, whereas others form piRNA clusters that regulate transposable elements; thus, these elements are expected to evolve under purifying selection. In contrast, other repeats evolve selfishly and produce genetic conflicts with their host species that drive adaptive evolution of host defense systems. However, the majority of repeats likely accumulate in eukaryotes in the absence of selection due to mechanisms of transposition and unequal crossing over. Even these neutral repeats may indirectly influence genome evolution as they reach high abundance. In this Special Issue, the contributing authors explore these questions from a range of perspectives.

Structure and Function of Plant Genomes

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1468445383
Total Pages : 492 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Structure and Function of Plant Genomes by : Orio Ciferri

Download or read book Structure and Function of Plant Genomes written by Orio Ciferri and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the presentations of the principal speakers at the NATO Advanced Study Institute held at Porto Portese, Italy,23 August - 2 September, 1982. This meeting was the third in a series devoted to the molecular biology of plants. The initial meeting was held in Strasbourg, France in 1976 (J. Weil and L. Bogorad, organizers), and the second in Edinburgh, Scotland in 1979 (C. Leaver, organizer). As in these previous meetings, we have attempted to cover the major topics of plant molecular biology so as to promote the integration of information emerging at an accelerating rate from the various sub-disciplines of the field. In addition, we have introduced several topics, unique to higher plants, that have not yet been approached with the tools of molec ular biology, but that should present new and important aspects of plants amenable to study in terms of DNA -+ RNA -+ Protein. This meeting also served to inaugerate the new International Society for Plant Molecular Biology. The need for this society is, like the NATO meetings themselves, an indication of the growth, vitalitv and momentum of this field of research.

Tandem Repeats in Genes, Proteins, and Disease

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Author :
Publisher : Humana
ISBN 13 : 9781493963003
Total Pages : 0 pages
Book Rating : 4.9/5 (63 download)

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Book Synopsis Tandem Repeats in Genes, Proteins, and Disease by : Danny M. Hatters

Download or read book Tandem Repeats in Genes, Proteins, and Disease written by Danny M. Hatters and published by Humana. This book was released on 2016-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The genomes of humans, as well as many other species, are interspersed with hundreds of thousands of tandem repeats of DNA sequences. Those tandem repeats located as codons within open reading frames encode amino acid runs, such as polyglutamine and polyalanine. Tandem repeats have not only been implicated in biological evolution, development and function but also in a large collection of human disorders. In Tandem Repeats in Genes, Proteins, and Disease: Methods and Protocols, expert researchers in the field detail many methods covering the analysis of tandem repeats in DNA, RNA and protein, in healthy and diseased states. This will include molecular genetics, molecular biology, biochemistry, proteomics, biophysics, cell biology, and molecular and cellular approaches to animal models of tandem repeat disorders. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoratative and Practical, Tandem Repeats in Genes, Proteins, and Disease: Methods and Protocols aids scientists in continuing to study the unique methodological challenges that come from repetitive DNA and poly-amino acid sequences.

Molecular Biology of The Cell

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Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of The Cell by : Bruce Alberts

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Essential Readings in Evolutionary Biology

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Publisher : JHU Press
ISBN 13 : 1421413051
Total Pages : 572 pages
Book Rating : 4.4/5 (214 download)

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Book Synopsis Essential Readings in Evolutionary Biology by : Francisco J. Ayala

Download or read book Essential Readings in Evolutionary Biology written by Francisco J. Ayala and published by JHU Press. This book was released on 2014-03-15 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traces scholarly thought from the nineteenth-century birth of evolutionary biology to the mapping of the human genome through forty-eight essays, arranged in chronological order, each preceded by a one-page essay that explains the significance of the chosen work.

Transposable Elements and Evolution

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Publisher : Springer Science & Business Media
ISBN 13 : 9401120285
Total Pages : 355 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Transposable Elements and Evolution by : J. F. McDonald

Download or read book Transposable Elements and Evolution written by J. F. McDonald and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the summer of 1992 a distinguished group of molecular, population and evolutionary geneticists assembled on the campus of the University of Georgia in Athens, USA to discuss the relevance of their research to the role played by transposable elements (TEs) in evolution. The meeting consisted of a series of informal discussions of issues brought up in papers written by the participants and distributed among them prior to the meeting. These papers and the transcripts of the ensuing discussions are presented in this volume.

Evolutionary Sequence Divergence Within Repeated DNA Families of Higher Plant Genomes

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Author :
Publisher :
ISBN 13 :
Total Pages : 190 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Evolutionary Sequence Divergence Within Repeated DNA Families of Higher Plant Genomes by : Richard Saul Preisler

Download or read book Evolutionary Sequence Divergence Within Repeated DNA Families of Higher Plant Genomes written by Richard Saul Preisler and published by . This book was released on 1980 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genome Evolution

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Publisher : Academic Press
ISBN 13 :
Total Pages : 410 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Genome Evolution by : Gabriel A. Dover

Download or read book Genome Evolution written by Gabriel A. Dover and published by Academic Press. This book was released on 1982 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: