Frontiers in Anti-Infective Agents: Volume 6

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Author :
Publisher : Bentham Science Publishers
ISBN 13 : 9814998435
Total Pages : 194 pages
Book Rating : 4.8/5 (149 download)

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Book Synopsis Frontiers in Anti-Infective Agents: Volume 6 by : Parvesh Singh

Download or read book Frontiers in Anti-Infective Agents: Volume 6 written by Parvesh Singh and published by Bentham Science Publishers. This book was released on 2021-11-17 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anti-infective agents are a distinct class of pharmacologically important molecules that have served mankind in different capacities to combat life-threatening pathological conditions. They include antibacterial, antifungal, antiviral, antituberculosis, antimalarial, and urinary anti-infective agents. However, evolutionary changes, adaptations, and the development of new strains of pathogenic microorganisms have reduced the therapeutic efficacy of existing drugs, thus, limiting their clinical utility over the years. Frontiers in Anti-Infective Agents Volume 6 is a collection of notable research efforts, successful anti-infective drug development programs, and a comprehensive overview of successful and unsuccessful clinical trials conducted in this domain. This volume continues from the last one with interesting reviews on 1) “Reverse Vaccinology” for vaccination design using computational data to identify vaccine targets, 2) leptospirosis, 3) phage therapy for bacterial infections, 4) quorum sensing inhibitors from natural products, and 5) nitrogen and oxygen-based heterocyclic compounds that can act as anti-infective agents. The volume, therefore, covers a range of frontier topics on anti-infective research and development. This compilation is a timely reference for postgraduate scholars and researchers seeking updates in specific areas of anti-infective drug development. Allied healthcare professionals (clinical and public healthcare professionals) can also benefit from the information presented within.

Frontiers in Clinical Drug Research - Anti Infectives: Volume 6

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Author :
Publisher : Bentham Science Publishers
ISBN 13 : 9811425736
Total Pages : 229 pages
Book Rating : 4.8/5 (114 download)

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Book Synopsis Frontiers in Clinical Drug Research - Anti Infectives: Volume 6 by : Atta-ur-Rahman

Download or read book Frontiers in Clinical Drug Research - Anti Infectives: Volume 6 written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2020-08-20 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Clinical Drug Research – Anti infectives is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. The scope of the book series covers a range of topics including the chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of infectious diseases. Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents. Frontiers in Clinical Drug Research – Anti infectives is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of anti infective drug discovery and epidemiology. The sixth volume of this series features these interesting reviews: - Direct-acting antiviral drugs for treatment of Hepatitis C virus infection - Plant lattices as anti-infective compounds - Antimicrobial materials and devices for biomedical applications - Recent advances in the treatment of toxoplasmosis - Antimicrobial immunoglobulin prophylaxis and therapy - Targeting Magnesium Homeostasis as Potential Anti-Infective Strategy Against Mycobacteria

Frontiers in Anti-Infective Agents: Volume 5

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Author :
Publisher : Bentham Science Publishers
ISBN 13 : 9814998400
Total Pages : 242 pages
Book Rating : 4.8/5 (149 download)

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Book Synopsis Frontiers in Anti-Infective Agents: Volume 5 by : Parvesh Singh

Download or read book Frontiers in Anti-Infective Agents: Volume 5 written by Parvesh Singh and published by Bentham Science Publishers. This book was released on 2021-09-14 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anti-infective agents are a distinct class of pharmacologically important molecules that has served mankind in different capacities to combat life-threating pathologic conditions. They include antibacterial, antifungal, antiviral, antituberculosis, antimalarial and urinary anti-infective agents. However, evolutionary changes, adaptations and development of pathogenic microorganisms strains the therapeutic efficacy of these drugs thus limiting their clinical utility over the years. Frontiers in Anti-Infective Agents Volume 5 is a collection of notable research efforts, successful anti-infective drug development programmes and a comprehensive overview of the successes and failures of recent clinical trials in this domain. The volume covers interesting topics: 1) the treatment of acute wounds with the vikut® formula, 2) anti-infective treatment of ocular diseases and 3) sars-cov vaccine development and antimicrobial therapy for SARS symptoms. A chapter summarizing recent anti-infective approaches rounds up the contents of this volume. This volume is a timely reference for postgraduate scholars and researchers seeking updates in specific areas of anti-infective drug development. Allied healthcare professionals (clinical and public healthcare professionals) can also benefit from the information presented within.

Pregnancy and Anti-Infective Agents

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Author :
Publisher : Bentham Science Publishers
ISBN 13 : 9811479577
Total Pages : 186 pages
Book Rating : 4.8/5 (114 download)

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Book Synopsis Pregnancy and Anti-Infective Agents by : Ricardo Ney Cobucci

Download or read book Pregnancy and Anti-Infective Agents written by Ricardo Ney Cobucci and published by Bentham Science Publishers. This book was released on 2020-11-19 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: This concise clinical reference facilitates health consultants and professionals for determining treatment options for some common prenatal and postpartum infections during pregnancy and the puerperium in patients. Key Features - Presents 9 organized, easy to read chapters on anti-infective agents for pregnant patients - Covers pharmacokinetics and pharmacodynamics of relevant anti-infective agents - Includes information on classification and safety of anti-infective agents - Includes treatment of urinary tract infections - Covers medications for sexually transmitted diseases, including a complete section dedicated to HIV medication - Provides information about vulvovaginal infections - Covers the treatment of toxoplasmosis in pregnancy - innovates with information about herbal remedies for infection for patients during pregnancy and breastfeeding Pregnancy and Anti-Infective Agents is therefore, a valuable handbook that enables quick consultation on safe antibiotics for the treatment of a variety of infections in pregnancy.

Current Perspectives on Anti-Infective Agents

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Author :
Publisher : Bentham Science Publishers
ISBN 13 : 9811432724
Total Pages : 278 pages
Book Rating : 4.8/5 (114 download)

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Book Synopsis Current Perspectives on Anti-Infective Agents by : K. Tamreihao

Download or read book Current Perspectives on Anti-Infective Agents written by K. Tamreihao and published by Bentham Science Publishers. This book was released on 2019-11-18 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volume is a comprehensive documentation on major infectious diseases from tropical countries which pose a serious threat to global healthcare programs. These include diseases such as tuberculosis, AIDS, leishmaniasis (kala-azar), elephantiasis, malaria, leprosy, various fungal disorders and emergent viral diseases. Due to the widespread use of antibiotics, there is an emergence of drug-resistant pathogens in many regions. Hence, there is a need to search for novel, cost-effective bioactive compounds that demonstrate high efficacy and low toxicity in human cells from unexplored ecosystems to combat emerging drug-resistant pathogens. Chapters of this volume focus on the pathogenesis and etiology of each of the mentioned diseases, updated WHO reports wherever applicable, conventional drugs and their pharmacokinetics as well as new approaches to develop anti-infective agents. The authors also present a detailed report on ‘superbugs’ (multi-drug resistant pathogens) and new measures being taken up to eradicate them. Information about new antimicrobials (bioactive peptides and silk protein sericin) and the approaches taken by scientists and healthcare professionals for successful targeting of these molecules for human medicine. This volume is essential for general readers, healthcare professionals, researchers, and academicians actively involved in research on infectious diseases and anti-infective therapeutic drugs. [Series Introduction] Frontiers in Anti-Infective Agents is a book series that focuses on current and new antibiotics and vaccines. The series highlights the challenges faced by healthcare workers around the globe when facing epidemics caused by life-threatening pathogens along with the measures being taken to combat these challenges. The series is essential reading for all involved in infectious disease research including microbiologists, medical professionals, epidemiologists, and life science researchers.

Anti-infective Research and Development: Updates on Infection Mechanisms and Treatments

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Author :
Publisher : Bentham Science Publishers
ISBN 13 : 9811469563
Total Pages : 206 pages
Book Rating : 4.8/5 (114 download)

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Book Synopsis Anti-infective Research and Development: Updates on Infection Mechanisms and Treatments by : Gloria G. Guerrero Manriquez

Download or read book Anti-infective Research and Development: Updates on Infection Mechanisms and Treatments written by Gloria G. Guerrero Manriquez and published by Bentham Science Publishers. This book was released on 2020-10-19 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Frontiers in Anti-Infective Agents provides updates on the most recent studies about anti-infective agents, their mechanism of action, the relevant molecular targets and their implication in the development of novel antibiotics that have properties similar to their corresponding compounds of natural origin. The initial chapter covers the mode of action of natural antimycobacterial compounds such as nordihydroguaiaretic acid, α-mangostin and allicin, as well as antimicrobial peptides and their role in the innate and adaptive immune response leading to the decrease of microbial resistance. This is followed by updates on tuberculosis treatment concerning the immunological role of cells (airway epithelial cells, macrophages, neutrophils and T cells) along with their products (chemokines, cytokines) and other processes such as autophagy that influence the outcome of the host immune response to the infection. Contributors have also reviewed the latest knowledge in the cellular and molecular mechanisms that trigger a protective, immune response and the identification of the molecular targets for vaccine development, all of which are a key priority to develop control measures against Babesia species like Babesia bovis and Babesia bigemina. Additionally, the neuro-endocrine and neuro-immune mechanisms behind host responses against stress and environmental stimuli during infections are also covered in separate chapters. The volume also provides updates related to Helicobacter pylori pathogenesis. The reviews presented in Anti-infective Research and Development provide timely updates for scholars and professionals associated with the field of antimicrobial research and development.

Disease Control Priorities, Third Edition (Volume 6)

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Author :
Publisher : World Bank Publications
ISBN 13 : 1464805253
Total Pages : 1027 pages
Book Rating : 4.4/5 (648 download)

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Book Synopsis Disease Control Priorities, Third Edition (Volume 6) by : King K. Holmes

Download or read book Disease Control Priorities, Third Edition (Volume 6) written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Frontiers in Clinical Drug Research - CNS and Neurological Disorders

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Author :
Publisher : Bentham Science Publishers
ISBN 13 : 1608057755
Total Pages : 373 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis Frontiers in Clinical Drug Research - CNS and Neurological Disorders by : Atta-ur-Rahman

Download or read book Frontiers in Clinical Drug Research - CNS and Neurological Disorders written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2013-10-11 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Clinical Drug Research - CNS and Neurological Disorders is an ebook series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the ebook series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of contemporary molecular targets involved in neurological and CNS disorders. Reviews presented in the series are mainly focused on clinical and therapeutic aspects of novel drugs intended for these targets. Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critical information for developing clinical trials and devising research plans in the field of neurology. The second volume of this series features 8 chapters that cover a variety of topics including: -treatment of multiple sclerosis and schizophrenia -neurochemistry of tremors -relationship between GABA and Alzheimer’s disease therapy -relationship between neurological diseases and cancer -research on angiogenesis-related blindness

Video Atlas of Spine Surgical Techniques

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Publisher : Bentham Science Publishers
ISBN 13 : 1681081229
Total Pages : 512 pages
Book Rating : 4.6/5 (81 download)

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Book Synopsis Video Atlas of Spine Surgical Techniques by : Federico A. Landriel

Download or read book Video Atlas of Spine Surgical Techniques written by Federico A. Landriel and published by Bentham Science Publishers. This book was released on 2016-05-04 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: This video atlas covers a broad range of spinal surgical procedures. The volume includes a collection of high quality 3-to-8 minute videos of some of the most critical spine operations performed by internationally renowned expert surgeons. Key features of the book contents include: o Downloadable high quality video content with subtitles suitable for viewing on any display (A brief preview of the book content can be viewed at https://www.youtube.com/watch?v=SxMi4UFj7HA ) o Detailed descriptions of surgical indications, preoperative planning, patient positioning, surgical technique, complications, postoperative care and outcomes for each procedure o Full color images and illustrations highlighting different key stages of each surgical technique The video format allows skill development of its intended audience by conveying temporal and spatial details which often go unnoticed in photograph format. This volume will be of immense interest to both the novice and the experienced spinal surgeon as they can benefit from the visual guides presented in the book. It also serves as an ideal teaching tool for spine surgery units in medical schools.

Quorum Sensing vs Quorum Quenching: A Battle with No End in Sight

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Author :
Publisher : Springer
ISBN 13 : 9788132235484
Total Pages : 0 pages
Book Rating : 4.2/5 (354 download)

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Book Synopsis Quorum Sensing vs Quorum Quenching: A Battle with No End in Sight by : Vipin Chandra Kalia

Download or read book Quorum Sensing vs Quorum Quenching: A Battle with No End in Sight written by Vipin Chandra Kalia and published by Springer. This book was released on 2016-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial relationships with all life forms can be as free living, symbiotic or pathogenic. Human beings harbor 10 times more microbial cells than their own. Bacteria are found on the skin surface, in the gut and other body parts. Bacteria causing diseases are the most worrisome. Most of the infectious diseases are caused by bacterial pathogens with an ability to form biofilm. Bacteria within the biofilm are up to 1000 times more resistant to antibiotics. This has taken a more serious turn with the evolution of multiple drug resistant bacteria. Health Departments are making efforts to reduce high mortality and morbidity in man caused by them. Bacterial Quorum sensing (QS), a cell density dependent phenomenon is responsible for a wide range of expressions such as pathogenesis, biofilm formation, competence, sporulation, nitrogen fixation, etc. Majority of these organisms that are important for medical, agriculture, aquaculture, water treatment and remediation, archaeological departments are: Aeromonas, Acinetobacter, Bacillus, Clostridia, Enterococcus, Pseudomonas, Vibrio and Yersinia spp. Biosensors and models have been developed to detect QS systems. Strategies for inhibiting QS system through natural and synthetic compounds have been presented here. The biotechnological applications of QS inhibitors (QSIs) in diverse areas have also been dealt with. Although QSIs do not affect growth and are less likely to impose selective pressure on bacteria, however, a few reports have raised doubts on the fate of QSIs. This book addresses a few questions. Will bacteria develop mechanisms to evade QSIs? Are we watching yet another defeat at the hands of bacteria? Or will we be acting intelligently and survive the onslaughts of this Never Ending battle?

Frontiers in Drug Design & Discovery: Volume 10

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Publisher : Bentham Science Publishers
ISBN 13 : 9811421552
Total Pages : 261 pages
Book Rating : 4.8/5 (114 download)

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Book Synopsis Frontiers in Drug Design & Discovery: Volume 10 by : Atta-ur-Rahman

Download or read book Frontiers in Drug Design & Discovery: Volume 10 written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2021-02-03 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Drug Design and Discovery is a book series devoted to publishing the latest and the most important advances in drug design and discovery. Eminent scientists have contributed chapters focused on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, and structure-activity relationships. This book series should prove to be of interest to all pharmaceutical scientists who are involved in research in drug design and discovery and who wish to keep abreast of rapid and important developments in the field. The tenth volume of this series brings together reviews covering topics related to the treatment of neoplasms, systems biology, respiratory diseases among others. Topics included in this volume are: - Recombinant Protein Production: from Bench to Biopharming - Plant Virus Nanoparticles and Virus like Particles (VLPs): Applications in Medicine - MAO Inhibitory Activity Of 4, 5-Dihydro-1 HPyrazole Derivatives: A Platform To Design Novel Antidepressants - Flavonoids Antagonize Effects of Alcohol in Cultured Hippocampal Neurons: A Drug Discovery Study - Hybrid Smart Materials for Topical Drug Delivery: Application of Scaffolds.

Antibody-Drug Conjugates

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Publisher : John Wiley & Sons
ISBN 13 : 1119060842
Total Pages : 567 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Antibody-Drug Conjugates by : Kenneth J. Olivier, Jr.

Download or read book Antibody-Drug Conjugates written by Kenneth J. Olivier, Jr. and published by John Wiley & Sons. This book was released on 2016-11-14 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing practical and proven solutions for antibody-drug conjugate (ADC) drug discovery success in oncology, this book helps readers improve the drug safety and therapeutic efficacy of ADCs to kill targeted tumor cells. • Discusses the basics, drug delivery strategies, pharmacology and toxicology, and regulatory approval strategies • Covers the conduct and design of oncology clinical trials and the use of ADCs for tumor imaging • Includes case studies of ADCs in oncology drug development • Features contributions from highly-regarded experts on the frontlines of ADC research and development

How Selegiline ((-)-Deprenyl) Slows Brain Aging

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Publisher : Bentham Science Publishers
ISBN 13 : 1608054705
Total Pages : 161 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis How Selegiline ((-)-Deprenyl) Slows Brain Aging by : Joseph Knoll

Download or read book How Selegiline ((-)-Deprenyl) Slows Brain Aging written by Joseph Knoll and published by Bentham Science Publishers. This book was released on 2012-10-12 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: This e-book is a reference on Selegiline ((-)-Deprenyl) effects on the brain. Selegiline, described in thousands of research papers, is registered in over 60 countries. At present, more than one hundred preparations containing selegiline circulate in the global market under different brand names. They are widely used in the treatment of Parkinson's disease, Alzheimer's disease, major depression and as a geroprotective / anti-aging drug. ((-)-Deprenyl) selegiline, the first selective inhibitor of B-type MAO which, in contrast to the known MAO inhibitors, did not potentiate the effect of tyramine but inhibited it. the compound could be combined with levodopa in Parkinson's disease without signs of hypertensive reactions. the DATATOP study in the USA revealed that (-)-deprenyl delayed the onset of disability associated with early, otherwise untreated Parkinson's disease. the age-related decay of the supply of the brain with phenylethylamine (PEA), due to the progressive increase of MAO-B activity in the aging brain, and dopamine, due to the better than average decline of the dopaminergic neuronal activity during the postdevelopmental phase of life, are irresistible biochemical lesions of aging. the speed of deterioration of behavioral performances with the passing of time and longevity depends significantly on the pace of the worsening of these lesions. (-)-Deprenyl, increasing the supply of the brain with PEA and dopamine, counteracts this aging process. Maintenance of male rats from sexual maturity until death on ((-)-deprenyl) delays the age-related loss of the capacity to ejaculate, slows the age-related decline of learning ability and prolongs life. In humans, maintenance from sexual maturity on (-)-deprenyl (1 mg daily) is, for the time being, the most promising prophylactic treatment to fight against the age-related decay of behavioral performances, prolonging life, and preventing or delaying the onset of age-related neurodegenerative diseases such as Parkinson's and Alzheimer's. This e-book is a useful reference for graduate medical students, academic researchers in the field of neuropsychopharmacology, neurophysiology and gerontology and professional research groups in commercial organizations manufacturing selegiline preparations.

Bad Bug Book

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Author :
Publisher : Createspace Independent Publishing Platform
ISBN 13 : 9781495203619
Total Pages : 292 pages
Book Rating : 4.2/5 (36 download)

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Book Synopsis Bad Bug Book by : Mark Walderhaug

Download or read book Bad Bug Book written by Mark Walderhaug and published by Createspace Independent Publishing Platform. This book was released on 2014-01-14 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Bad Bug Book 2nd Edition, released in 2012, provides current information about the major known agents that cause foodborne illness.Each chapter in this book is about a pathogen—a bacterium, virus, or parasite—or a natural toxin that can contaminate food and cause illness. The book contains scientific and technical information about the major pathogens that cause these kinds of illnesses.A separate “consumer box” in each chapter provides non-technical information, in everyday language. The boxes describe plainly what can make you sick and, more important, how to prevent it.The information provided in this handbook is abbreviated and general in nature, and is intended for practical use. It is not intended to be a comprehensive scientific or clinical reference.The Bad Bug Book is published by the Center for Food Safety and Applied Nutrition (CFSAN) of the Food and Drug Administration (FDA), U.S. Department of Health and Human Services.

Antimicrobial Resistance

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Publisher :
ISBN 13 : 9789241564748
Total Pages : 232 pages
Book Rating : 4.5/5 (647 download)

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Book Synopsis Antimicrobial Resistance by : World Health Organization

Download or read book Antimicrobial Resistance written by World Health Organization and published by . This book was released on 2014 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Summary report published as technical document with reference number: WHO/HSE/PED/AIP/2014.2.

Medical Books and Serials in Print

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Publisher :
ISBN 13 :
Total Pages : 1316 pages
Book Rating : 4.2/5 (35 download)

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Book Synopsis Medical Books and Serials in Print by :

Download or read book Medical Books and Serials in Print written by and published by . This book was released on 1984 with total page 1316 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Topics in Anti-Cancer Research: Volume 8

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Author :
Publisher : Bentham Science Publishers
ISBN 13 : 9811404372
Total Pages : 182 pages
Book Rating : 4.8/5 (114 download)

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Book Synopsis Topics in Anti-Cancer Research: Volume 8 by : Atta-ur-Rahman

Download or read book Topics in Anti-Cancer Research: Volume 8 written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2019-12-31 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: Topics in Anti-Cancer Research covers new developments in the field of cancer. Novel drugs as anticancer agents include natural and synthetic phenazines and other anti-cancer compounds. It also encompasses the role of estrogen as endocrine disruptors and strategies targeting cancer stem cells for the treatment of different types of cancers, including myeloma and renal cell cancer. The diversity of researches and topics published in this eBook Series will be valuable to cancer researchers, clinicians, and cancer professionals aiming to develop novel anti-cancer targets for the treatment of various cancers. The topics covered in the eighth volume of this series are as follows: -Novel Drugs for Multiple Myeloma -Synthetic Estrogens are Endocrine Disruptors via Inhibition of AF1 Domain of ERs -Recent Progress of Phenazines as Anticancer Agents -Cancer Stem Cell Targeting for Anticancer Therapy: Strategies and Challenges