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Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Ivet Bahar
Publisher : Garland Science
ISBN 13 : 1351815016
Total Pages : 337 pages
Book Rating : 4.3/5 (518 download)
Download or read book Protein Actions: Principles and Modeling written by Ivet Bahar and published by Garland Science. This book was released on 2017-02-14 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein Actions: Principles and Modeling is aimed at graduates, advanced undergraduates, and any professional who seeks an introduction to the biological, chemical, and physical properties of proteins. Broadly accessible to biophysicists and biochemists, it will be particularly useful to student and professional structural biologists and molecular biophysicists, bioinformaticians and computational biologists, biological chemists (particularly drug designers) and molecular bioengineers. The book begins by introducing the basic principles of protein structure and function. Some readers will be familiar with aspects of this, but the authors build up a more quantitative approach than their competitors. Emphasizing concepts and theory rather than experimental techniques, the book shows how proteins can be analyzed using the disciplines of elementary statistical mechanics, energetics, and kinetics. These chapters illuminate how proteins attain biologically active states and the properties of those states. The book ends with a synopsis the roles of computational biology and bioinformatics in protein science.
Author : Amit Kessel
Publisher : CRC Press
ISBN 13 : 1498747213
Total Pages : 1423 pages
Book Rating : 4.4/5 (987 download)
Download or read book Introduction to Proteins written by Amit Kessel and published by CRC Press. This book was released on 2018-03-22 with total page 1423 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Proteins provides a comprehensive and state-of-the-art introduction to the structure, function, and motion of proteins for students, faculty, and researchers at all levels. The book covers proteins and enzymes across a wide range of contexts and applications, including medical disorders, drugs, toxins, chemical warfare, and animal behavior. Each chapter includes a Summary, Exercies, and References. New features in the thoroughly-updated second edition include: A brand-new chapter on enzymatic catalysis, describing enzyme biochemistry, classification, kinetics, thermodynamics, mechanisms, and applications in medicine and other industries. These are accompanied by multiple animations of biochemical reactions and mechanisms, accessible via embedded QR codes (which can be viewed by smartphones) An in-depth discussion of G-protein-coupled receptors (GPCRs) A wider-scale description of biochemical and biophysical methods for studying proteins, including fully accessible internet-based resources, such as databases and algorithms Animations of protein dynamics and conformational changes, accessible via embedded QR codes Additional features Extensive discussion of the energetics of protein folding, stability and interactions A comprehensive view of membrane proteins, with emphasis on structure-function relationship Coverage of intrinsically unstructured proteins, providing a complete, realistic view of the proteome and its underlying functions Exploration of industrial applications of protein engineering and rational drug design Each chapter includes a Summary, Exercies, and References Approximately 300 color images Downloadable solutions manual available at www.crcpress.com For more information, including all presentations, tables, animations, and exercises, as well as a complete teaching course on proteins' structure and function, please visit the author's website: http://ibis.tau.ac.il/wiki/nir_bental/index.php/Introduction_to_Proteins_Book. Praise for the first edition "This book captures, in a very accessible way, a growing body of literature on the structure, function and motion of proteins. This is a superb publication that would be very useful to undergraduates, graduate students, postdoctoral researchers, and instructors involved in structural biology or biophysics courses or in research on protein structure-function relationships." --David Sheehan, ChemBioChem, 2011 "Introduction to Proteins is an excellent, state-of-the-art choice for students, faculty, or researchers needing a monograph on protein structure. This is an immensely informative, thoroughly researched, up-to-date text, with broad coverage and remarkable depth. Introduction to Proteins would provide an excellent basis for an upper-level or graduate course on protein structure, and a valuable addition to the libraries of professionals interested in this centrally important field." --Eric Martz, Biochemistry and Molecular Biology Education, 2012
Author : Amit Kessel
Publisher : CRC Press
ISBN 13 : 1439810729
Total Pages : 623 pages
Book Rating : 4.4/5 (398 download)
Download or read book Introduction to Proteins written by Amit Kessel and published by CRC Press. This book was released on 2010-12-17 with total page 623 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the tools and techniques of structural biophysics assume greater roles in biological research and a range of application areas, learning how proteins behave becomes crucial to understanding their connection to the most basic and important aspects of life. With more than 350 color images throughout, Introduction to Proteins: Structure, Function, and Motion presents a unified, in-depth treatment of the relationship between the structure, dynamics, and function of proteins. Taking a structural–biophysical approach, the authors discuss the molecular interactions and thermodynamic changes that transpire in these highly complex molecules. The text incorporates various biochemical, physical, functional, and medical aspects. It covers different levels of protein structure, current methods for structure determination, energetics of protein structure, protein folding and folded state dynamics, and the functions of intrinsically unstructured proteins. The authors also clarify the structure–function relationship of proteins by presenting the principles of protein action in the form of guidelines. This comprehensive, color book uses numerous proteins as examples to illustrate the topics and principles and to show how proteins can be analyzed in multiple ways. It refers to many everyday applications of proteins and enzymes in medical disorders, drugs, toxins, chemical warfare, and animal behavior. Downloadable questions for each chapter are available at CRC Press Online.
Author : Lucjan Piela
Publisher : Elsevier
ISBN 13 : 0080466761
Total Pages : 1122 pages
Book Rating : 4.0/5 (84 download)
Download or read book Ideas of Quantum Chemistry written by Lucjan Piela and published by Elsevier. This book was released on 2006-11-28 with total page 1122 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ideas of Quantum Chemistry shows how quantum mechanics is applied to chemistry to give it a theoretical foundation. The structure of the book (a TREE-form) emphasizes the logical relationships between various topics, facts and methods. It shows the reader which parts of the text are needed for understanding specific aspects of the subject matter. Interspersed throughout the text are short biographies of key scientists and their contributions to the development of the field.Ideas of Quantum Chemistry has both textbook and reference work aspects. Like a textbook, the material is organized into digestable sections with each chapter following the same structure. It answers frequently asked questions and highlights the most important conclusions and the essential mathematical formulae in the text. In its reference aspects, it has a broader range than traditional quantum chemistry books and reviews virtually all of the pertinent literature. It is useful both for beginners as well as specialists in advanced topics of quantum chemistry. The book is supplemented by an appendix on the Internet.* Presents the widest range of quantum chemical problems covered in one book * Unique structure allows material to be tailored to the specific needs of the reader * Informal language facilitates the understanding of difficult topics
Author : Michael Williamson
Publisher : Garland Science
ISBN 13 : 1136665498
Total Pages : 464 pages
Book Rating : 4.1/5 (366 download)
Download or read book How Proteins Work written by Michael Williamson and published by Garland Science. This book was released on 2012-03-26 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: High-throughputomics' projects such as genome sequencing, structural genomics and proteomics mean that there is no shortage of information on proteins. But the more information we have, the harder it is to make sense of it, to know where to start, and to identify the important results. This book is a clear, up to date and authoritative account of
Author : Daniel J. Graham
Publisher : CRC Press
ISBN 13 : 0429647883
Total Pages : 245 pages
Book Rating : 4.4/5 (296 download)
Download or read book Invitation to Protein Sequence Analysis Through Probability and Information written by Daniel J. Graham and published by CRC Press. This book was released on 2019-02-06 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the remarkable information correspondences and probability structures of proteins. Correspondences are pervasive in biochemistry and bioinformatics: proteins share homologies, folding patterns, and mechanisms. Probability structures are just as paramount: folded state graphics reflect Angstrom-scale maps of electron density. The author explores protein sequences (primary structures), both individually and in sets (systems) with the help of probability and information tools. This perspective will enhance the reader’s knowledge of how an important class of molecules is designed and put to task in natural systems, and how we can approach class members in hands-on ways.
Author : Wolfgang Alt
Publisher : Birkhäuser
ISBN 13 : 303488043X
Total Pages : 306 pages
Book Rating : 4.0/5 (348 download)
Download or read book Polymer and Cell Dynamics written by Wolfgang Alt and published by Birkhäuser. This book was released on 2012-12-06 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymer and cell dynamics play an important role in processes like tumor growth, metastasis, embryogenesis, immune reactions and regeneration. Based on an international workshop on numerical simulations of polymer and cell dynamics in Bad Honnef (Germany) in 2000, this volume provides an overview of the relevant mathematical and numerical methods, their applications and limits. Polymer and Cell Dynamics will be of interest to scientists and advanced undergraduates.
Author : Matthew He
Publisher : John Wiley & Sons
ISBN 13 : 1118099524
Total Pages : 231 pages
Book Rating : 4.1/5 (18 download)
Download or read book Mathematics of Bioinformatics written by Matthew He and published by John Wiley & Sons. This book was released on 2011-03-16 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematics of Bioinformatics: Theory, Methods, and Applications provides a comprehensive format for connecting and integrating information derived from mathematical methods and applying it to the understanding of biological sequences, structures, and networks. Each chapter is divided into a number of sections based on the bioinformatics topics and related mathematical theory and methods. Each topic of the section is comprised of the following three parts: an introduction to the biological problems in bioinformatics; a presentation of relevant topics of mathematical theory and methods to the bioinformatics problems introduced in the first part; an integrative overview that draws the connections and interfaces between bioinformatics problems/issues and mathematical theory/methods/applications.
Author : Srikanta Sen
Publisher : CRC Press
ISBN 13 : 143983914X
Total Pages : 184 pages
Book Rating : 4.4/5 (398 download)
Download or read book Thermostable Proteins written by Srikanta Sen and published by CRC Press. This book was released on 2016-04-19 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the basic structural, thermodynamic and kinetic principles are covered and molecular strategies for the adaptation to high temperatures revealed by structure analysis are delineated. The roles of fluctuations, hydration and internal packing are thoroughly dicussed. Enzymes with a particular industrial importance, the subtilisin-like serine proteases, have been extensively studied by protein engineering. One extensive chapter is devoted to the present state of knowledge concerning structure-function relations and the origin of the their structural stability. Last but not least, computational and experimental approaches for the design of proteins with increased thermal stability based on sequences or 3D structures are present
Author : Marketa J. Zvelebil
Publisher : Garland Science
ISBN 13 : 9780815340249
Total Pages : 804 pages
Book Rating : 4.3/5 (42 download)
Download or read book Understanding Bioinformatics written by Marketa J. Zvelebil and published by Garland Science. This book was released on 2008 with total page 804 pages. Available in PDF, EPUB and Kindle. Book excerpt: Suitable for advanced undergraduates & postgraduates, this book provides a definitive guide to bioinformatics. It takes a conceptual approach & guides the reader from first principles through to an understanding of the computational techniques & the key algorithms.
Author : Ilan Samish
Publisher : Humana
ISBN 13 : 9781493966356
Total Pages : 0 pages
Book Rating : 4.9/5 (663 download)
Download or read book Computational Protein Design written by Ilan Samish and published by Humana. This book was released on 2016-12-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim this volume is to present the methods, challenges, software, and applications of this widespread and yet still evolving and maturing field. Computational Protein Design, the first book with this title, guides readers through computational protein design approaches, software and tailored solutions to specific case-study targets. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Computational Protein Design aims to ensure successful results in the further study of this vital field.
Author : Habib Izadkhah
Publisher : Academic Press
ISBN 13 : 0128238364
Total Pages : 382 pages
Book Rating : 4.1/5 (282 download)
Download or read book Deep Learning in Bioinformatics written by Habib Izadkhah and published by Academic Press. This book was released on 2022-01-08 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deep Learning in Bioinformatics: Techniques and Applications in Practice introduces the topic in an easy-to-understand way, exploring how it can be utilized for addressing important problems in bioinformatics, including drug discovery, de novo molecular design, sequence analysis, protein structure prediction, gene expression regulation, protein classification, biomedical image processing and diagnosis, biomolecule interaction prediction, and in systems biology. The book also presents theoretical and practical successes of deep learning in bioinformatics, pointing out problems and suggesting future research directions. Dr. Izadkhah provides valuable insights and will help researchers use deep learning techniques in their biological and bioinformatics studies. - Introduces deep learning in an easy-to-understand way - Presents how deep learning can be utilized for addressing some important problems in bioinformatics - Presents the state-of-the-art algorithms in deep learning and bioinformatics - Introduces deep learning libraries in bioinformatics
Author : Crina Grosan
Publisher : Springer
ISBN 13 : 3540732977
Total Pages : 410 pages
Book Rating : 4.5/5 (47 download)
Download or read book Hybrid Evolutionary Algorithms written by Crina Grosan and published by Springer. This book was released on 2007-08-29 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited volume is targeted at presenting the latest state-of-the-art methodologies in "Hybrid Evolutionary Algorithms". The chapters deal with the theoretical and methodological aspects, as well as various applications to many real world problems from science, technology, business or commerce. Overall, the book has 14 chapters including an introductory chapter giving the fundamental definitions and some important research challenges. The contributions were selected on the basis of fundamental ideas/concepts rather than the thoroughness of techniques deployed.
Author : Jean-Paul Renaud
Publisher : John Wiley & Sons
ISBN 13 : 1118681010
Total Pages : 706 pages
Book Rating : 4.1/5 (186 download)
Download or read book Structural Biology in Drug Discovery written by Jean-Paul Renaud and published by John Wiley & Sons. This book was released on 2020-02-05 with total page 706 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the most comprehensive and up-to-date overview of structure-based drug discovery covering both experimental and computational approaches, Structural Biology in Drug Discovery: Methods, Techniques, and Practices describes principles, methods, applications, and emerging paradigms of structural biology as a tool for more efficient drug development. Coverage includes successful examples, academic and industry insights, novel concepts, and advances in a rapidly evolving field. The combined chapters, by authors writing from the frontlines of structural biology and drug discovery, give readers a valuable reference and resource that: Presents the benefits, limitations, and potentiality of major techniques in the field such as X-ray crystallography, NMR, neutron crystallography, cryo-EM, mass spectrometry and other biophysical techniques, and computational structural biology Includes detailed chapters on druggability, allostery, complementary use of thermodynamic and kinetic information, and powerful approaches such as structural chemogenomics and fragment-based drug design Emphasizes the need for the in-depth biophysical characterization of protein targets as well as of therapeutic proteins, and for a thorough quality assessment of experimental structures Illustrates advances in the field of established therapeutic targets like kinases, serine proteinases, GPCRs, and epigenetic proteins, and of more challenging ones like protein-protein interactions and intrinsically disordered proteins
Author : Malin Masreliez Young
Publisher :
ISBN 13 :
Total Pages : 382 pages
Book Rating : 4.:/5 (82 download)
Download or read book Computational Investigations of Protein Sequence-structure Relations written by Malin Masreliez Young and published by . This book was released on 1999 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Carolyn D. Berdanier
Publisher : CRC Press
ISBN 13 : 1351083562
Total Pages : 591 pages
Book Rating : 4.3/5 (51 download)
Download or read book Nutrition and Gene Expression written by Carolyn D. Berdanier and published by CRC Press. This book was released on 2018-01-18 with total page 591 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutrition and Gene Expression is devoted to exploring the tissue-specific and developmental aspects of the interaction between nutrients and the genome. The book discusses chemical sensitivity in relation to the ability of cells to detect nutrients; reviews the means by which lower organisms respond to nutrients; and provides examples on how each of the classes of nutrients affects genetic transcription, mRNA translation or stability. The receptor-mediated actions of vitamin D and retinoic acid on gene expression are discussed, including the case of bone formation and dissolution. Other important topics covered in the volume include newly discovered effects of fatty acids on regulating gene expression, the effects of diet on mRNA editing, the interplay between dietary carbohydrates and proteins in regulating metabolism of liver cells, the effects of metal ions on protein synthesis, and much more. Nutrition and Gene Expression is an important reference for nutritionists, physiologists, biochemists, clinical nutritionists, pharmaceutical researchers, geneticists, and food scientists.
