Principles of Translational Science in Medicine

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Author :
Publisher : Academic Press
ISBN 13 : 0128007214
Total Pages : 365 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Principles of Translational Science in Medicine by : Martin Wehling

Download or read book Principles of Translational Science in Medicine written by Martin Wehling and published by Academic Press. This book was released on 2015-04-02 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Translational Science in Medicine: From Bench to Bedside, Second Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing numbers of new chemical/biological entities (NCEs or NBEs) as shown in FDA statistics. The book is ideal for use as a guide for biomedical scientists to establish a systematic approach to translational medicine. Provides an in-depth description of novel tools for the assessment of translatability of trials to balance risk and improve projects at any given stage of product development New chapters deal with translational issues in the fastest growing population (the elderly), case studies, translatability assessment tools, and advances in nanotherapies Details IPR issues of translation, especially for public-private-partnerships Contains contributions from world leaders in translational medicine, including the former NIH director and authorities from various European regulatory institutions

Follow the Money: Funding Research in a Large Academic Health Center

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Publisher : Lulu.com
ISBN 13 : 0996324216
Total Pages : 233 pages
Book Rating : 4.9/5 (963 download)

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Book Synopsis Follow the Money: Funding Research in a Large Academic Health Center by : Henry R. Bourne

Download or read book Follow the Money: Funding Research in a Large Academic Health Center written by Henry R. Bourne and published by Lulu.com. This book was released on 2016 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Threatened by sharp cuts in state government support and stagnant federal research funding, US public research universities are becoming fragile ecosystems. By charting flows of research dollars through a leading public research university-the University of California, San Francisco (UCSF)-this book illuminates how such schools work to cope with these funding threats and how the challenges and coping strategies affect organization and direction of research. Academic leaders, faculty, administrators, and students will learn how a complex academic health center manages its revenues, expenses, and diverse academic cultures. For the first time, they can begin to understand arcane mysteries of indirect cost recovery, sponsored funds, capital investment, endowments, debt, and researchers' salaries.

Sustainability in high performance sport

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Publisher : Routledge
ISBN 13 : 1317327926
Total Pages : 133 pages
Book Rating : 4.3/5 (173 download)

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Book Synopsis Sustainability in high performance sport by : Natalie Barker-Ruchti

Download or read book Sustainability in high performance sport written by Natalie Barker-Ruchti and published by Routledge. This book was released on 2017-10-02 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: Success in high performance sport is highly valued in today’s world, with lucrative contracts, sponsorship deals, and opportunities for celebrity status balanced against substantial investments of time and energy, and high chances of failure. With pressure mounting on athletes and coaches to make the most of athletic investments, the temptation to make health-related or ethical compromises is growing. Sustainability in High Performance Sport examines the pressures faced by coaches and athletes, and considers how sustainable science can offer alternative pathways to sporting excellence. By applying principles relating to carrying capacities, complexity and uncertainty, production and consumption, and ethics, this unique book provides new ways of thinking about both enduring and emerging challenges. With a scope that includes themes such as coaching practices, coach-athlete relationships, over-training and injuries, the development of sporting expertise, and doping, Sustainability in High Performance Sport is the most comprehensive exploration of sustainability in elite sport available. It is an invaluable resource for anybody with an interest in achieving long-term success in high performance sport. This book was originally published as a special issue of Reflective Practice.

Bioethics, Genetics and Sport

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Publisher : Routledge
ISBN 13 : 1317485386
Total Pages : 366 pages
Book Rating : 4.3/5 (174 download)

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Book Synopsis Bioethics, Genetics and Sport by : Silvia Camporesi

Download or read book Bioethics, Genetics and Sport written by Silvia Camporesi and published by Routledge. This book was released on 2018-04-09 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in genetics and related biotechnologies are having a profound effect on sport, raising important ethical questions about the limits and possibilities of the human body. Drawing on real case studies and grounded in rigorous scientific evidence, this book offers an ethical critique of current practices and explores the intersection of genetics, ethics and sport. Written by two of the world's leading authorities on the ethics of biotechnology in sport, the book addresses the philosophical implications of the latest scientific developments and technological data. Distinguishing fact from popular myth and science fiction, it covers key topics such as the genetic basis of sport performance and the role of genetic testing in talent identification and development. Its ten chapters discuss current debates surrounding issues such as the shifting relationship between genetics, sports medicine and sports science, gene enhancement, gene transfer technology, doping and disability sport. The first book to be published on this important subject in more than a decade, this is fascinating reading for anyone with an interest in the ethics of sport, bioethics or sport performance.

From Bench to BedsideTrauma, Tumors, Spine, Functional Neurosurgery

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 9535126288
Total Pages : 170 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis From Bench to BedsideTrauma, Tumors, Spine, Functional Neurosurgery by : Francesco Signorelli

Download or read book From Bench to BedsideTrauma, Tumors, Spine, Functional Neurosurgery written by Francesco Signorelli and published by BoD – Books on Demand. This book was released on 2016-09-28 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is written for graduate students, researchers, and practitioners who are interested in learning how the knowledge from research can be implemented in clinical competences. The first section is dedicated to deep brain stimulation, a surgical procedure which is the paramount example of how clinical practice can take advantage from fundamental research. The second section gathers four chapters on four different topics and illustrates how significant is the challenge to translate scientific advances into clinical practice because the route from evidence to action is not always obvious. It is hoped that this book will stimulate the interest in the process of translating research into practice for a broader range of neurosurgical topics than the one covered by this book, which could result in a forthcoming more comprehensive publication.

Tangled Diagnoses

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Publisher : University of Chicago Press
ISBN 13 : 022653426X
Total Pages : 326 pages
Book Rating : 4.2/5 (265 download)

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Book Synopsis Tangled Diagnoses by : Ilana Löwy

Download or read book Tangled Diagnoses written by Ilana Löwy and published by University of Chicago Press. This book was released on 2018-04-19 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the late nineteenth century, medicine has sought to foster the birth of healthy children by attending to the bodies of pregnant women, through what we have come to call prenatal care. Women, and not their unborn children, were the initial focus of that medical attention, but prenatal diagnosis in its present form, which couples scrutiny of the fetus with the option to terminate pregnancy, came into being in the early 1970s. Tangled Diagnoses examines the multiple consequences of the widespread diffusion of this medical innovation. Prenatal testing, Ilana Löwy argues, has become mainly a risk-management technology—the goal of which is to prevent inborn impairments, ideally through the development of efficient therapies but in practice mainly through the prevention of the birth of children with such impairments. Using scholarship, interviews, and direct observation in France and Brazil of two groups of professionals who play an especially important role in the production of knowledge about fetal development—fetopathologists and clinical geneticists—to expose the real-life dilemmas prenatal testing creates, this book will be of interest to anyone concerned with the sociopolitical conditions of biomedical innovation, the politics of women’s bodies, disability, and the ethics of modern medicine.

Bone Cancer

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Publisher : Academic Press
ISBN 13 : 0323899900
Total Pages : 1080 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Bone Cancer by : Dominique Heymann

Download or read book Bone Cancer written by Dominique Heymann and published by Academic Press. This book was released on 2021-09-23 with total page 1080 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone Cancer: Bone Sarcomas and Bone Metastases - From Bench to Bedside, Third Edition comprehensively investigates key discoveries in the field of bone biology. New aspects of bone cancer biology are treated in new chapters covering exosomes, autophagy, and metabolism. These have led to the development of entirely new areas for investigation, such as therapies which combine surgery and biological approaches. The Third Edition expands on the original overview of bone cancer development (physiology and pathophysiology), with 40% new material. Each chapter has been written by internationally recognized specialists on the bone cancer microenvironment, bone metastases, osteoclast biology in bone cancer, proteomics, bone niche, circulating tumor cells, and clinical trials. Given the global prevalence of breast and prostate cancers, knowledge of bone biology has become essential for everyone within the medical and cancer research communities. Bone Cancer: Bone Sarcomas and Bone Metastases - From Bench to Bedside continues to offer the only translational reference to cover all aspects of primary bone cancer and bone metastases. This revision opens the door to myeloma with two short chapters dedicated to this bone-associated disease. Covers the broad field of bone sarcomas and bone metastases from basic research to clinical approaches Presents comprehensive and translational overview of biological and clinical aspects of bone cancers, discussing pathophysiology from genetic and molecular levels using the most recent evidence Provides a common language for cancer researchers, bone biologists, oncologists, and radiologists to discuss bone tumors and how bone cancer metastases affects each major organ system Offers insights to research clinicians (oncologists and radiologists) into understanding the molecular basis of bone cancer, leading to more well-informed diagnoses and treatment of tumors and metastases Offers insights to bone biologists into how clinical observations and practices can feed back into the research cycle and, therefore, can contribute to the development of more targeted genomic and proteomic assays

Imperfect Pregnancies

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Publisher : JHU Press
ISBN 13 : 1421423634
Total Pages : 295 pages
Book Rating : 4.4/5 (214 download)

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Book Synopsis Imperfect Pregnancies by : Ilana Löwy

Download or read book Imperfect Pregnancies written by Ilana Löwy and published by JHU Press. This book was released on 2017-12 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction : scrutinized fetuses -- Born imperfect : birth defects before prenatal diagnosis -- Karyotypes -- Human malformations -- From prenatal diagnosis to prenatal screening -- Sex chromosome aneuploidies -- PND and new genomics approaches -- Conclusion : PND's slippery slopes, imagined and real

Routledge Handbook of Genomics, Health and Society

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Publisher : Routledge
ISBN 13 : 1315451670
Total Pages : 474 pages
Book Rating : 4.3/5 (154 download)

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Book Synopsis Routledge Handbook of Genomics, Health and Society by : Sahra Gibbon

Download or read book Routledge Handbook of Genomics, Health and Society written by Sahra Gibbon and published by Routledge. This book was released on 2018-04-17 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook provides an essential resource at the interface of Genomics, Health and Society, and forms a crucial research tool for both new students and established scholars across biomedicine and social sciences. Building from and extending the first Routledge Handbook of Genetics and Society, the book offers a comprehensive introduction to pivotal themes within the field, an overview of the current state of the art knowledge on genomics, science and society, and an outline of emerging areas of research. Key themes addressed include the way genomic based DNA technologies have become incorporated into diverse arenas of clinical practice and research whilst also extending beyond the clinic; the role of genomics in contemporary ‘bioeconomies’; how challenges in the governance of medical genomics can both reconfigure and stabilise regulatory processes and jurisdictional boundaries; how questions of diversity and justice are situated across different national and transnational terrains of genomic research; and how genomics informs – and is shaped by – developments in fields such as epigenetics, synthetic biology, stem cell, microbial and animal model research. Chapters 13 and 28 of this book are freely available as downloadable Open Access PDFs at http://www.taylorfrancis.com, under a Creative Commons Attribution-Non Commercial-No Derivatives (CC-BY-NC-ND) 4.0 license.

From Bench to Bedside, to Track and Field

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (897 download)

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Book Synopsis From Bench to Bedside, to Track and Field by : Silvia Camporesi

Download or read book From Bench to Bedside, to Track and Field written by Silvia Camporesi and published by . This book was released on 2013 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biomedical Product Development: Bench to Bedside

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Publisher : Springer Nature
ISBN 13 : 3030356264
Total Pages : 164 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Biomedical Product Development: Bench to Bedside by : Babak Arjmand

Download or read book Biomedical Product Development: Bench to Bedside written by Babak Arjmand and published by Springer Nature. This book was released on 2020-02-05 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook covers all the steps in manufacturing a biomedical product from bench to bedside. It specifically focuses on quality assurance and management and explains the different good practice principles in the various phases of product development as well as how to fulfill them: Good laboratory practice, good manufacturing practice and good clinical practice. It provides readers with the know-how to design biomedical experiments to ensure quality and integrity, to plan and conduct standard preclinical studies and to assure the quality of the final manufactured biomedical products. Importantly, it also addresses ethical concerns and considerations. The book discusses the guidelines and ethical considerations for preclinical and clinical studies, to allow readers to identify safety concerns regarding biomedical products and to improve pre-clinical studies for the development of better products. This textbook is a valuable guide for biomedical students (B.Sc., M.S., and Ph.D. students) in the field of molecular medicine, medical biotechnology, stem cell research and related areas, as well as for professionals such as quality control staff, tissue bankers, policy-makers and health professionals.

The Complete Book of Colleges, 2012 Edition

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Publisher : Princeton Review
ISBN 13 : 0375427392
Total Pages : 1442 pages
Book Rating : 4.3/5 (754 download)

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Book Synopsis The Complete Book of Colleges, 2012 Edition by : Princeton Review (Firm)

Download or read book The Complete Book of Colleges, 2012 Edition written by Princeton Review (Firm) and published by Princeton Review. This book was released on 2011-08-15 with total page 1442 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents a comprehensive guide to 1,571 colleges and universities, and includes information on academic programs, admissions requirements, tuition costs, housing, financial aid, campus life, organizations, athletic programs, and student services.

The Western Humanities Review

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Publisher :
ISBN 13 :
Total Pages : 808 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis The Western Humanities Review by :

Download or read book The Western Humanities Review written by and published by . This book was released on 2015 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Stem Cell Anthology

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Publisher : Academic Press
ISBN 13 : 0123756839
Total Pages : 425 pages
Book Rating : 4.1/5 (237 download)

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Book Synopsis Stem Cell Anthology by :

Download or read book Stem Cell Anthology written by and published by Academic Press. This book was released on 2009-10-22 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fields of stem cell research, regenerative medicine, tissue engineering, and cloning are very closely related. It is important for researchers in each of these disciplines to be aware of the methods and principles in the others. Elsevier publishes some of the highest individual references in these areas. Bringing together the principles, applications, and basic understanding in these related areas of science will provide a new reference which is serve the needs of a variety of researchers. Edited by Dr. Bruce Carlson, Stem Cell Anthology will be valuable to researchers and students who need to save time and link concepts to principles, applications, and methods in order to work more effectively and see links for potential collaborations. Includes a collection of chapters by leaders in the stem cell field including the first researchers to discover iPS cells and multiple Nobel Laureates Provides the most detailed introduction to basic properties of major embryonic and adult stem cells by highlighting breakthrough discoveries in the nervous system, spinal cord, heart, pancreas, epidermis, musculo-skeletal, retina - leading areas of stem cell research in human application Details technical laboratory set up for practitioners, technicians, and administrators

Clinical and Translational Science

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Publisher : Academic Press
ISBN 13 : 0080920195
Total Pages : 600 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Clinical and Translational Science by : David Robertson

Download or read book Clinical and Translational Science written by David Robertson and published by Academic Press. This book was released on 2009-03-02 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical or translational science is the field of study devoted to investigating human health and disease, interventions and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. New molecular tools and diagnostic technologies based on clinical and translational research have lead to a better understanding of human disease and the application of new therapeutics for enhanced health. Clinical and Translational Science is designed as the most authoritative and modern resource for the broad range of investigators in various medical specialties taking on the challenge of clinical research. Prepared with an international perspective, this resource begins with experimental design and investigative tools to set the scene for readers. It then moves on to human genetics and pharmacology with a focus on statistics, epidemiology, genomic information, drug discovery and development, and clinical trials. Finally, it turns to legal, social, and ethical issues of clinical research concluding with a discussion of future prospects to provide readers with a comprehensive view of the this developing area of science. Clinical research is one of the fastest growing fields in private practice and academic medicine with practical biological, physiological, cellular, and therapeutic applications Contributions from international leaders provide insight into background and future understanding for clinical and translational science Provides the structure for complete instruction and guidance on the subject from fundamental principles, approaches and infrastructure to human genetics, human pharmacology, research in special populations, the societal context of human research, and the future of human research

Physicians’ Pathways to Non-Traditional Careers and Leadership Opportunities

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Publisher : Springer Science & Business Media
ISBN 13 : 1461405513
Total Pages : 380 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Physicians’ Pathways to Non-Traditional Careers and Leadership Opportunities by : Richard D. Urman

Download or read book Physicians’ Pathways to Non-Traditional Careers and Leadership Opportunities written by Richard D. Urman and published by Springer Science & Business Media. This book was released on 2011-12-04 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasingly, physicians are leveraging their medical training and expertise to pursue careers in non-traditional arenas. Their goals are diverse: · Explore consulting as a way to improve patient care · Lay the foundation for a career in academic medicine · Provide leadership in healthcare · Strengthen ties between a clinic and the community · Broaden one’s experience as a medical student · As a journalist or writer, open a window onto medicine for non-experts Some physicians will pursue another degree, while others may not, in anticipation of moving into public service, business, education, law, or organized medicine. Their common ground is the desire to enhance their professional fulfillment. Drs. Urman and Ehrenfeld’s book features individual chapters on the wide array of non-traditional careers for physicians, each one written by an outstanding leader in medicine who him- or herself has successfully forged a unique career path. A final chapter brings together fascinating brief profiles – “case studies” – of physicians who have distinguished themselves professionally outside of traditional settings. Suitable for readers at any point in their medical career – practitioners, fellows, residents, and medical students – who want to explore possibilities beyond traditional medical practice, the book also sets out common-sense advice on topics such as work-life balance, mentorship, and the relationship between personality and job satisfaction.

Empathy

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Publisher : MIT Press
ISBN 13 : 0262016613
Total Pages : 335 pages
Book Rating : 4.2/5 (62 download)

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Book Synopsis Empathy by : Jean Decety

Download or read book Empathy written by Jean Decety and published by MIT Press. This book was released on 2012 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent work on empathy theory, research, and applications, by scholars from disciplines ranging from neuroscience to psychoanalysis. There are many reasons for scholars to investigate empathy. Empathy plays a crucial role in human social interaction at all stages of life; it is thought to help motivate positive social behavior, inhibit aggression, and provide the affective and motivational bases for moral development; it is a necessary component of psychotherapy and patient-physician interactions. This volume covers a wide range of topics in empathy theory, research, and applications, helping to integrate perspectives as varied as anthropology and neuroscience. The contributors discuss the evolution of empathy within the mammalian brain and the development of empathy in infants and children; the relationships among empathy, social behavior, compassion, and altruism; the neural underpinnings of empathy; cognitive versus emotional empathy in clinical practice; and the cost of empathy. Taken together, the contributions significantly broaden the interdisciplinary scope of empathy studies, reporting on current knowledge of the evolutionary, social, developmental, cognitive, and neurobiological aspects of empathy and linking this capacity to human communication, including in clinical practice and medical education.