Statistical Genomics

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Publisher : Springer Nature
ISBN 13 : 1071629867
Total Pages : 377 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Statistical Genomics by : Brooke Fridley

Download or read book Statistical Genomics written by Brooke Fridley and published by Springer Nature. This book was released on 2023-03-16 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a collection of protocols from researchers in the statistical genomics field. Chapters focus on integrating genomics with other “omics” data, such as transcriptomics, epigenomics, proteomics, metabolomics, and metagenomics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Statistical Genomics hopes that by covering these diverse and timely topics researchers are provided insights into future directions and priorities of pan-omics and the precision medicine era.

Bayesian and Frequentist Regression Methods

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Publisher : Springer Science & Business Media
ISBN 13 : 1441909257
Total Pages : 700 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Bayesian and Frequentist Regression Methods by : Jon Wakefield

Download or read book Bayesian and Frequentist Regression Methods written by Jon Wakefield and published by Springer Science & Business Media. This book was released on 2013-01-04 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bayesian and Frequentist Regression Methods provides a modern account of both Bayesian and frequentist methods of regression analysis. Many texts cover one or the other of the approaches, but this is the most comprehensive combination of Bayesian and frequentist methods that exists in one place. The two philosophical approaches to regression methodology are featured here as complementary techniques, with theory and data analysis providing supplementary components of the discussion. In particular, methods are illustrated using a variety of data sets. The majority of the data sets are drawn from biostatistics but the techniques are generalizable to a wide range of other disciplines.

Mixed Effects Models for Complex Data

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Publisher : CRC Press
ISBN 13 : 9781420074086
Total Pages : 431 pages
Book Rating : 4.0/5 (74 download)

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Book Synopsis Mixed Effects Models for Complex Data by : Lang Wu

Download or read book Mixed Effects Models for Complex Data written by Lang Wu and published by CRC Press. This book was released on 2009-11-11 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although standard mixed effects models are useful in a range of studies, other approaches must often be used in correlation with them when studying complex or incomplete data. Mixed Effects Models for Complex Data discusses commonly used mixed effects models and presents appropriate approaches to address dropouts, missing data, measurement errors, censoring, and outliers. For each class of mixed effects model, the author reviews the corresponding class of regression model for cross-sectional data. An overview of general models and methods, along with motivating examples After presenting real data examples and outlining general approaches to the analysis of longitudinal/clustered data and incomplete data, the book introduces linear mixed effects (LME) models, generalized linear mixed models (GLMMs), nonlinear mixed effects (NLME) models, and semiparametric and nonparametric mixed effects models. It also includes general approaches for the analysis of complex data with missing values, measurement errors, censoring, and outliers. Self-contained coverage of specific topics Subsequent chapters delve more deeply into missing data problems, covariate measurement errors, and censored responses in mixed effects models. Focusing on incomplete data, the book also covers survival and frailty models, joint models of survival and longitudinal data, robust methods for mixed effects models, marginal generalized estimating equation (GEE) models for longitudinal or clustered data, and Bayesian methods for mixed effects models. Background material In the appendix, the author provides background information, such as likelihood theory, the Gibbs sampler, rejection and importance sampling methods, numerical integration methods, optimization methods, bootstrap, and matrix algebra. Failure to properly address missing data, measurement errors, and other issues in statistical analyses can lead to severely biased or misleading results. This book explores the biases that arise when naïve methods are used and shows which approaches should be used to achieve accurate results in longitudinal data analysis.

Bayesian Data Analysis in Ecology Using Linear Models with R, BUGS, and Stan

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Publisher : Academic Press
ISBN 13 : 0128016787
Total Pages : 329 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Bayesian Data Analysis in Ecology Using Linear Models with R, BUGS, and Stan by : Franzi Korner-Nievergelt

Download or read book Bayesian Data Analysis in Ecology Using Linear Models with R, BUGS, and Stan written by Franzi Korner-Nievergelt and published by Academic Press. This book was released on 2015-04-04 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bayesian Data Analysis in Ecology Using Linear Models with R, BUGS, and STAN examines the Bayesian and frequentist methods of conducting data analyses. The book provides the theoretical background in an easy-to-understand approach, encouraging readers to examine the processes that generated their data. Including discussions of model selection, model checking, and multi-model inference, the book also uses effect plots that allow a natural interpretation of data. Bayesian Data Analysis in Ecology Using Linear Models with R, BUGS, and STAN introduces Bayesian software, using R for the simple modes, and flexible Bayesian software (BUGS and Stan) for the more complicated ones. Guiding the ready from easy toward more complex (real) data analyses ina step-by-step manner, the book presents problems and solutions—including all R codes—that are most often applicable to other data and questions, making it an invaluable resource for analyzing a variety of data types. - Introduces Bayesian data analysis, allowing users to obtain uncertainty measurements easily for any derived parameter of interest - Written in a step-by-step approach that allows for eased understanding by non-statisticians - Includes a companion website containing R-code to help users conduct Bayesian data analyses on their own data - All example data as well as additional functions are provided in the R-package blmeco

Statistical Rethinking

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Publisher : CRC Press
ISBN 13 : 1315362619
Total Pages : 488 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Statistical Rethinking by : Richard McElreath

Download or read book Statistical Rethinking written by Richard McElreath and published by CRC Press. This book was released on 2018-01-03 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical Rethinking: A Bayesian Course with Examples in R and Stan builds readers’ knowledge of and confidence in statistical modeling. Reflecting the need for even minor programming in today’s model-based statistics, the book pushes readers to perform step-by-step calculations that are usually automated. This unique computational approach ensures that readers understand enough of the details to make reasonable choices and interpretations in their own modeling work. The text presents generalized linear multilevel models from a Bayesian perspective, relying on a simple logical interpretation of Bayesian probability and maximum entropy. It covers from the basics of regression to multilevel models. The author also discusses measurement error, missing data, and Gaussian process models for spatial and network autocorrelation. By using complete R code examples throughout, this book provides a practical foundation for performing statistical inference. Designed for both PhD students and seasoned professionals in the natural and social sciences, it prepares them for more advanced or specialized statistical modeling. Web Resource The book is accompanied by an R package (rethinking) that is available on the author’s website and GitHub. The two core functions (map and map2stan) of this package allow a variety of statistical models to be constructed from standard model formulas.

Beyond Multiple Linear Regression

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Publisher : CRC Press
ISBN 13 : 1439885400
Total Pages : 436 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Beyond Multiple Linear Regression by : Paul Roback

Download or read book Beyond Multiple Linear Regression written by Paul Roback and published by CRC Press. This book was released on 2021-01-14 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: Beyond Multiple Linear Regression: Applied Generalized Linear Models and Multilevel Models in R is designed for undergraduate students who have successfully completed a multiple linear regression course, helping them develop an expanded modeling toolkit that includes non-normal responses and correlated structure. Even though there is no mathematical prerequisite, the authors still introduce fairly sophisticated topics such as likelihood theory, zero-inflated Poisson, and parametric bootstrapping in an intuitive and applied manner. The case studies and exercises feature real data and real research questions; thus, most of the data in the textbook comes from collaborative research conducted by the authors and their students, or from student projects. Every chapter features a variety of conceptual exercises, guided exercises, and open-ended exercises using real data. After working through this material, students will develop an expanded toolkit and a greater appreciation for the wider world of data and statistical modeling. A solutions manual for all exercises is available to qualified instructors at the book’s website at www.routledge.com, and data sets and Rmd files for all case studies and exercises are available at the authors’ GitHub repo (https://github.com/proback/BeyondMLR)

Econometric Analysis of Count Data

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Publisher : Springer Science & Business Media
ISBN 13 : 9783540404040
Total Pages : 324 pages
Book Rating : 4.4/5 (4 download)

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Book Synopsis Econometric Analysis of Count Data by : Rainer Winkelmann

Download or read book Econometric Analysis of Count Data written by Rainer Winkelmann and published by Springer Science & Business Media. This book was released on 2003 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many other sections have been entirely rewritten and extended."--BOOK JACKET.

Generalized Linear Mixed Models

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Publisher : CRC Press
ISBN 13 : 1498755585
Total Pages : 671 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Generalized Linear Mixed Models by : Walter W. Stroup

Download or read book Generalized Linear Mixed Models written by Walter W. Stroup and published by CRC Press. This book was released on 2024-05-21 with total page 671 pages. Available in PDF, EPUB and Kindle. Book excerpt: Generalized Linear Mixed Models: Modern Concepts, Methods, and Applications (2nd edition) presents an updated introduction to linear modeling using the generalized linear mixed model (GLMM) as the overarching conceptual framework. For students new to statistical modeling, this book helps them see the big picture – linear modeling as broadly understood and its intimate connection with statistical design and mathematical statistics. For readers experienced in statistical practice, but new to GLMMs, the book provides a comprehensive introduction to GLMM methodology and its underlying theory. Unlike textbooks that focus on classical linear models or generalized linear models or mixed models, this book covers all of the above as members of a unified GLMM family of linear models. In addition to essential theory and methodology, this book features a rich collection of examples using SAS® software to illustrate GLMM practice. This second edition is updated to reflect lessons learned and experience gained regarding best practices and modeling choices faced by GLMM practitioners. New to this edition are two chapters focusing on Bayesian methods for GLMMs. Key Features: • Most statistical modeling books cover classical linear models or advanced generalized and mixed models; this book covers all members of the GLMM family – classical and advanced models. • Incorporates lessons learned from experience and on-going research to provide up-to-date examples of best practices. • Illustrates connections between statistical design and modeling: guidelines for translating study design into appropriate model and in-depth illustrations of how to implement these guidelines; use of GLMM methods to improve planning and design. • Discusses the difference between marginal and conditional models, differences in the inference space they are intended to address and when each type of model is appropriate. • In addition to likelihood-based frequentist estimation and inference, provides a brief introduction to Bayesian methods for GLMMs. Walt Stroup is an Emeritus Professor of Statistics. He served on the University of Nebraska statistics faculty for over 40 years, specializing in statistical modeling and statistical design. He is a Fellow of the American Statistical Association, winner of the University of Nebraska Outstanding Teaching and Innovative Curriculum Award and author or co-author of three books on mixed models and their extensions. Marina Ptukhina (Pa-too-he-nuh), PhD, is an Associate Professor of Statistics at Whitman College. She is interested in statistical modeling, design and analysis of research studies and their applications. Her research includes applications of statistics to economics, biostatistics and statistical education. Ptukhina earned a PhD in Statistics from the University of Nebraska-Lincoln, a Master of Science degree in Mathematics from Texas Tech University and a Specialist degree in Management from The National Technical University "Kharkiv Polytechnic Institute." Julie Garai, PhD, is a Data Scientist at Loop. She earned her PhD in Statistics from the University of Nebraska-Lincoln and a bachelor’s degree in Mathematics and Spanish from Doane College. Dr Garai actively collaborates with statisticians, psychologists, ecologists, forest scientists, software engineers, and business leaders in academia and industry. In her spare time, she enjoys leisurely walks with her dogs, dance parties with her children, and playing the trombone.

Bayesian Data Analysis, Third Edition

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Publisher : CRC Press
ISBN 13 : 1439840954
Total Pages : 677 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Bayesian Data Analysis, Third Edition by : Andrew Gelman

Download or read book Bayesian Data Analysis, Third Edition written by Andrew Gelman and published by CRC Press. This book was released on 2013-11-01 with total page 677 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its third edition, this classic book is widely considered the leading text on Bayesian methods, lauded for its accessible, practical approach to analyzing data and solving research problems. Bayesian Data Analysis, Third Edition continues to take an applied approach to analysis using up-to-date Bayesian methods. The authors—all leaders in the statistics community—introduce basic concepts from a data-analytic perspective before presenting advanced methods. Throughout the text, numerous worked examples drawn from real applications and research emphasize the use of Bayesian inference in practice. New to the Third Edition Four new chapters on nonparametric modeling Coverage of weakly informative priors and boundary-avoiding priors Updated discussion of cross-validation and predictive information criteria Improved convergence monitoring and effective sample size calculations for iterative simulation Presentations of Hamiltonian Monte Carlo, variational Bayes, and expectation propagation New and revised software code The book can be used in three different ways. For undergraduate students, it introduces Bayesian inference starting from first principles. For graduate students, the text presents effective current approaches to Bayesian modeling and computation in statistics and related fields. For researchers, it provides an assortment of Bayesian methods in applied statistics. Additional materials, including data sets used in the examples, solutions to selected exercises, and software instructions, are available on the book’s web page.

Introduction to WinBUGS for Ecologists

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Publisher : Academic Press
ISBN 13 : 0123786061
Total Pages : 321 pages
Book Rating : 4.1/5 (237 download)

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Book Synopsis Introduction to WinBUGS for Ecologists by : Marc Kéry

Download or read book Introduction to WinBUGS for Ecologists written by Marc Kéry and published by Academic Press. This book was released on 2010-07-19 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to WinBUGS for Ecologists introduces applied Bayesian modeling to ecologists using the highly acclaimed, free WinBUGS software. It offers an understanding of statistical models as abstract representations of the various processes that give rise to a data set. Such an understanding is basic to the development of inference models tailored to specific sampling and ecological scenarios. The book begins by presenting the advantages of a Bayesian approach to statistics and introducing the WinBUGS software. It reviews the four most common statistical distributions: the normal, the uniform, the binomial, and the Poisson. It describes the two different kinds of analysis of variance (ANOVA): one-way and two- or multiway. It looks at the general linear model, or ANCOVA, in R and WinBUGS. It introduces generalized linear model (GLM), i.e., the extension of the normal linear model to allow error distributions other than the normal. The GLM is then extended contain additional sources of random variation to become a generalized linear mixed model (GLMM) for a Poisson example and for a binomial example. The final two chapters showcase two fairly novel and nonstandard versions of a GLMM. The first is the site-occupancy model for species distributions; the second is the binomial (or N-) mixture model for estimation and modeling of abundance. - Introduction to the essential theories of key models used by ecologists - Complete juxtaposition of classical analyses in R and Bayesian analysis of the same models in WinBUGS - Provides every detail of R and WinBUGS code required to conduct all analyses - Companion Web Appendix that contains all code contained in the book and additional material (including more code and solutions to exercises)

Applying Generalized Linear Models

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Publisher : Springer Science & Business Media
ISBN 13 : 038722730X
Total Pages : 265 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Applying Generalized Linear Models by : James K. Lindsey

Download or read book Applying Generalized Linear Models written by James K. Lindsey and published by Springer Science & Business Media. This book was released on 2008-01-15 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes how generalised linear modelling procedures can be used in many different fields, without becoming entangled in problems of statistical inference. The author shows the unity of many of the commonly used models and provides readers with a taste of many different areas, such as survival models, time series, and spatial analysis, and of their unity. As such, this book will appeal to applied statisticians and to scientists having a basic grounding in modern statistics. With many exercises at the end of each chapter, it will equally constitute an excellent text for teaching applied statistics students and non- statistics majors. The reader is assumed to have knowledge of basic statistical principles, whether from a Bayesian, frequentist, or direct likelihood point of view, being familiar at least with the analysis of the simpler normal linear models, regression and ANOVA.

Medical Statistics at a Glance

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Publisher : John Wiley & Sons
ISBN 13 : 1118782445
Total Pages : 181 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Medical Statistics at a Glance by : Aviva Petrie

Download or read book Medical Statistics at a Glance written by Aviva Petrie and published by John Wiley & Sons. This book was released on 2013-11-08 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical Statistics at a Glance is a concise and accessible introduction and revision aid for this complex subject. The self-contained chapters explain the underlying concepts of medical statistics and provide a guide to the most commonly used statistical procedures. This new edition of Medical Statistics at a Glance: Presents key facts accompanied by clear and informative tables and diagrams Focuses on illustrative examples which show statistics in action, with an emphasis on the interpretation of computer data analysis rather than complex hand calculations Includes extensive cross-referencing, a comprehensive glossary of terms and flow-charts to make it easier to choose appropriate tests Now provides the learning objectives for each chapter Includes a new chapter on Developing Prognostic Scores Includes new or expanded material on study management, multi-centre studies, sequential trials, bias and different methods to remove confounding in observational studies, multiple comparisons, ROC curves and checking assumptions in a logistic regression analysis The companion website at www.medstatsaag.com contains supplementary material including an extensive reference list and multiple choice questions (MCQs) with interactive answers for self-assessment. Medical Statistics at a Glance will appeal to all medical students, junior doctors and researchers in biomedical and pharmaceutical disciplines. Reviews of the previous editions "The more familiar I have become with this book, the more I appreciate the clear presentation and unthreatening prose. It is now a valuable companion to my formal statistics course." –International Journal of Epidemiology "I heartily recommend it, especially to first years, but it's equally appropriate for an intercalated BSc or Postgraduate research. If statistics give you headaches - buy it. If statistics are all you think about - buy it." –GKT Gazette "...I unreservedly recommend this book to all medical students, especially those that dislike reading reams of text. This is one book that will not sit on your shelf collecting dust once you have graduated and will also function as a reference book." –4th Year Medical Student, Barts and the London Chronicle, Spring 2003

Continuous Multivariate Distributions, Volume 1

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Publisher : John Wiley & Sons
ISBN 13 : 0471654035
Total Pages : 752 pages
Book Rating : 4.4/5 (716 download)

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Book Synopsis Continuous Multivariate Distributions, Volume 1 by : Samuel Kotz

Download or read book Continuous Multivariate Distributions, Volume 1 written by Samuel Kotz and published by John Wiley & Sons. This book was released on 2004-04-05 with total page 752 pages. Available in PDF, EPUB and Kindle. Book excerpt: Continuous Multivariate Distributions, Volume 1, Second Edition provides a remarkably comprehensive, self-contained resource for this critical statistical area. It covers all significant advances that have occurred in the field over the past quarter century in the theory, methodology, inferential procedures, computational and simulational aspects, and applications of continuous multivariate distributions. In-depth coverage includes MV systems of distributions, MV normal, MV exponential, MV extreme value, MV beta, MV gamma, MV logistic, MV Liouville, and MV Pareto distributions, as well as MV natural exponential families, which have grown immensely since the 1970s. Each distribution is presented in its own chapter along with descriptions of real-world applications gleaned from the current literature on continuous multivariate distributions and their applications.

Applied Econometrics with R

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Publisher : Springer Science & Business Media
ISBN 13 : 0387773185
Total Pages : 229 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Applied Econometrics with R by : Christian Kleiber

Download or read book Applied Econometrics with R written by Christian Kleiber and published by Springer Science & Business Media. This book was released on 2008-12-10 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: R is a language and environment for data analysis and graphics. It may be considered an implementation of S, an award-winning language initially - veloped at Bell Laboratories since the late 1970s. The R project was initiated by Robert Gentleman and Ross Ihaka at the University of Auckland, New Zealand, in the early 1990s, and has been developed by an international team since mid-1997. Historically, econometricians have favored other computing environments, some of which have fallen by the wayside, and also a variety of packages with canned routines. We believe that R has great potential in econometrics, both for research and for teaching. There are at least three reasons for this: (1) R is mostly platform independent and runs on Microsoft Windows, the Mac family of operating systems, and various ?avors of Unix/Linux, and also on some more exotic platforms. (2) R is free software that can be downloaded and installed at no cost from a family of mirror sites around the globe, the Comprehensive R Archive Network (CRAN); hence students can easily install it on their own machines. (3) R is open-source software, so that the full source code is available and can be inspected to understand what it really does, learn from it, and modify and extend it. We also like to think that platform independence and the open-source philosophy make R an ideal environment for reproducible econometric research.

Generalized Poisson Distributions

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Publisher : CRC Press
ISBN 13 : 9780824778637
Total Pages : 320 pages
Book Rating : 4.7/5 (786 download)

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Book Synopsis Generalized Poisson Distributions by : P. C. Consul

Download or read book Generalized Poisson Distributions written by P. C. Consul and published by CRC Press. This book was released on 1988-12-22 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents 28 bar diagrams that illustrate the versatility of the generalized Poisson model and discusses stochastic processes leading to the generalized Poisson distribution. Examines theoretical properties that vary in difficulty, includes proofs for numerous theorems, explores confidence intervals

Statistics for Health Data Science

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Publisher : Springer Nature
ISBN 13 : 3030598896
Total Pages : 238 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Statistics for Health Data Science by : Ruth Etzioni

Download or read book Statistics for Health Data Science written by Ruth Etzioni and published by Springer Nature. This book was released on 2021-01-04 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Students and researchers in the health sciences are faced with greater opportunity and challenge than ever before. The opportunity stems from the explosion in publicly available data that simultaneously informs and inspires new avenues of investigation. The challenge is that the analytic tools required go far beyond the standard methods and models of basic statistics. This textbook aims to equip health care researchers with the most important elements of a modern health analytics toolkit, drawing from the fields of statistics, health econometrics, and data science. This textbook is designed to overcome students’ anxiety about data and statistics and to help them to become confident users of appropriate analytic methods for health care research studies. Methods are presented organically, with new material building naturally on what has come before. Each technique is motivated by a topical research question, explained in non-technical terms, and accompanied by engaging explanations and examples. In this way, the authors cultivate a deep (“organic”) understanding of a range of analytic techniques, their assumptions and data requirements, and their advantages and limitations. They illustrate all lessons via analyses of real data from a variety of publicly available databases, addressing relevant research questions and comparing findings to those of published studies. Ultimately, this textbook is designed to cultivate health services researchers that are thoughtful and well informed about health data science, rather than data analysts. This textbook differs from the competition in its unique blend of methods and its determination to ensure that readers gain an understanding of how, when, and why to apply them. It provides the public health researcher with a way to think analytically about scientific questions, and it offers well-founded guidance for pairing data with methods for valid analysis. Readers should feel emboldened to tackle analysis of real public datasets using traditional statistical models, health econometrics methods, and even predictive algorithms. Accompanying code and data sets are provided in an author site: https://roman-gulati.github.io/statistics-for-health-data-science/

Negative Binomial Regression

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Publisher : Cambridge University Press
ISBN 13 : 1139500066
Total Pages : 573 pages
Book Rating : 4.1/5 (395 download)

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Book Synopsis Negative Binomial Regression by : Joseph M. Hilbe

Download or read book Negative Binomial Regression written by Joseph M. Hilbe and published by Cambridge University Press. This book was released on 2011-03-17 with total page 573 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition of Hilbe's Negative Binomial Regression is a substantial enhancement to the popular first edition. The only text devoted entirely to the negative binomial model and its many variations, nearly every model discussed in the literature is addressed. The theoretical and distributional background of each model is discussed, together with examples of their construction, application, interpretation and evaluation. Complete Stata and R codes are provided throughout the text, with additional code (plus SAS), derivations and data provided on the book's website. Written for the practising researcher, the text begins with an examination of risk and rate ratios, and of the estimating algorithms used to model count data. The book then gives an in-depth analysis of Poisson regression and an evaluation of the meaning and nature of overdispersion, followed by a comprehensive analysis of the negative binomial distribution and of its parameterizations into various models for evaluating count data.