Free Radicals in Biology and Medicine

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Author :
Publisher : Oxford University Press
ISBN 13 : 0198717474
Total Pages : 961 pages
Book Rating : 4.1/5 (987 download)

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Book Synopsis Free Radicals in Biology and Medicine by : Barry Halliwell

Download or read book Free Radicals in Biology and Medicine written by Barry Halliwell and published by Oxford University Press. This book was released on 2015 with total page 961 pages. Available in PDF, EPUB and Kindle. Book excerpt: Free Radicals in Biology and Medicine has become a classic text in the field of free radical and antioxidant research. Now in its fifth edition, the book has been comprehensively rewritten and updated whilst maintaining the clarity of its predecessors. Two new chapters discuss 'in vivo' and 'dietary' antioxidants, the first emphasising the role of peroxiredoxins and integrated defence mechanisms which allow useful roles for ROS, and the second containing new information on the role of fruits, vegetables, and vitamins in health and disease. This new edition also contains expanded coverage of the mechanisms of oxidative damage to lipids, DNA, and proteins (and the repair of such damage), and the roles played by reactive species in signal transduction, cell survival, death, human reproduction, defence mechanisms of animals and plants against pathogens, and other important biological events. The methodologies available to measure reactive species and oxidative damage (and their potential pitfalls) have been fully updated, as have the topics of phagocyte ROS production, NADPH oxidase enzymes, and toxicology. There is a detailed and critical evaluation of the role of free radicals and other reactive species in human diseases, especially cancer, cardiovascular, chronic inflammatory and neurodegenerative diseases. New aspects of ageing are discussed in the context of the free radical theory of ageing. This book is recommended as a comprehensive introduction to the field for students, educators, clinicians, and researchers. It will also be an invaluable companion to all those interested in the role of free radicals in the life and biomedical sciences.

Free Radicals in Biology and Medicine

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Author :
Publisher : Oxford University Press, USA
ISBN 13 : 0198717482
Total Pages : 961 pages
Book Rating : 4.1/5 (987 download)

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Book Synopsis Free Radicals in Biology and Medicine by : Barry Halliwell

Download or read book Free Radicals in Biology and Medicine written by Barry Halliwell and published by Oxford University Press, USA. This book was released on 2015 with total page 961 pages. Available in PDF, EPUB and Kindle. Book excerpt: Free Radicals in Biology and Medicine has become a classic text in the field of free radical and antioxidant research. Now in its fifth edition, the book has been comprehensively rewritten and updated whilst maintaining the clarity of its predecessors. Two new chapters discuss 'in vivo' and 'dietary' antioxidants, the first emphasising the role of peroxiredoxins and integrated defence mechanisms which allow useful roles for ROS, and the second containing new information on the role of fruits, vegetables, and vitamins in health and disease. This new edition also contains expanded coverage of the mechanisms of oxidative damage to lipids, DNA, and proteins (and the repair of such damage), and the roles played by reactive species in signal transduction, cell survival, death, human reproduction, defence mechanisms of animals and plants against pathogens, and other important biological events. The methodologies available to measure reactive species and oxidative damage (and their potential pitfalls) have been fully updated, as have the topics of phagocyte ROS production, NADPH oxidase enzymes, and toxicology. There is a detailed and critical evaluation of the role of free radicals and other reactive species in human diseases, especially cancer, cardiovascular, chronic inflammatory and neurodegenerative diseases. New aspects of ageing are discussed in the context of the free radical theory of ageing. This book is recommended as a comprehensive introduction to the field for students, educators, clinicians, and researchers. It will also be an invaluable companion to all those interested in the role of free radicals in the life and biomedical sciences.

Free Radicals in Chemistry, Biology and Medicine

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Author :
Publisher :
ISBN 13 :
Total Pages : 560 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Free Radicals in Chemistry, Biology and Medicine by : Toshikazu Yoshikawa

Download or read book Free Radicals in Chemistry, Biology and Medicine written by Toshikazu Yoshikawa and published by . This book was released on 2000 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Oxygen Radicals in Biology and Medicine

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1468455680
Total Pages : 1064 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Oxygen Radicals in Biology and Medicine by : Michael Simic

Download or read book Oxygen Radicals in Biology and Medicine written by Michael Simic and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 1064 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is based on the papers presented at the "Fourth International Congress on Oxygen Radicals (4-ICOR)," held June 27 - July 3, 1987, at the University of California, La Jolla. The chapters deal with the phenomena associated with highly reactive oxygen species (hydroxy, peroxy, alkoxy, aroxy, and superoxide radicals, as well as singlet oxygen) and their peroxidation products (hydrogen peroxide, hydroperoxides, peroxides, and epoxides) as they relate to the fields of chemistry, food technology, nutrition, biology, pharmacology, and medicine. The kinetics, energetics, and mechanistic aspects of the reactions of these species and the interrelationship of oxygen radicals (or any other free radicals) and peroxidized products have been emphasized. Special attention is focused on the mechanisms of the generation of free radicals and peroxy products in biosystems and on the adverse effects of these radicals and products in humans. The topics span the continuum from the simple chemistry of model systems to the complex considerations of clinical medicine. The book also explores the mechanisms of agents that protect against free radicals and peroxy products in vitro and in vivo. These agents include antioxidants used in materials, food antioxidants, physiological antioxidants, and antioxienzymes (SOD, glutathione peroxidase, and catalases). The use of these inhibitors to prevent damage to organs being prepared for transplantation, thereby maintaining the quality of transplanted organs and/or extending their "shelf-life," also is examined.

Excited States and Free Radicals in Biology and Medicine

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Publisher :
ISBN 13 :
Total Pages : 456 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Excited States and Free Radicals in Biology and Medicine by : R. V. Bensasson

Download or read book Excited States and Free Radicals in Biology and Medicine written by R. V. Bensasson and published by . This book was released on 1993 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Excited states and free radicals are involved in the normal physiology of living systems, in pathological processes (including lipid peroxidation, inflammation, Parkinson's disease, cancer, and aging), in the mechanisms of drug action, and in the photochemotherapies such as the PUVA therapy for skin diseases and PDT for cancer. This text introduces the reader to this rapidly expanding field, one that lies at the borderlines of physics, chemistry, biology, pharmacology, and medicine. The authors explore in particular how time-resolved spectroscopic methods have found solutions at the molecular level to biological and medical problems. Topics include the nature of excited states and free radicals and the techniques for their study, activated oxygen species, DNA, proteins, carotenoids and photosynthetic reaction centers, photodermatology and melanogenesis, and aspects of cancer related to radio-, chemo-, and photodynamic therapy. Researchers and graduate students in photochemistry, photobiology, photomedicine, radiation chemistry and biology, and cancer therapies will find this book to be of very significant interest.

Free Radicals in Biology and Environment

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9780792345022
Total Pages : 520 pages
Book Rating : 4.3/5 (45 download)

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Book Synopsis Free Radicals in Biology and Environment by : F. Minisci

Download or read book Free Radicals in Biology and Environment written by F. Minisci and published by Springer Science & Business Media. This book was released on 1997-03-31 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our understanding of the quantitative aspects of free radical chemistry and the involvement of radicals in such areas as biology, medicine, the environment, etc., has developed spectacularly over recent years, yet the various topics are commonly discussed separately, in specific meetings and specialised publications. Free Radicals in Biology and Environment draws together two important areas of free radical chemistry, using as a bridge the fundamental physical chemistry of free radicals (spectroscopic detection of free radicals, evaluation of absolute rate constants, elucidation of mechanisms of free radical reactions and catalysis, photochemical and radiation processes, etc.). The most relevant topics covered are the EPR detection of radicals in biochemical systems and in pollutant formation and degradation, oxidation processes in biology and in the troposphere, radiation and induced damage, and atmospheric pollutants arising from incomplete combustion. Also covered are the chemistry and biochemistry of nitric oxide and peroxynitrite, the chemistry and biochemistry of DNA radicals, the role of radicals in myeloperoxidase, lignineperoxidase, radicals and cardiovascular injury, radiation and the fragmentation of cells and tissues.

Free Radical Medicine and Biology

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 1789851432
Total Pages : 132 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Free Radical Medicine and Biology by :

Download or read book Free Radical Medicine and Biology written by and published by BoD – Books on Demand. This book was released on 2020-07-15 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although free radicals perform some useful immune functions, they can also damage healthy cells through a process called oxidation. Antioxidants reduce the effect of free radicals by binding together with these harmful molecules, decreasing their destructive power. This book highlights various issues of free radical biology from the perspective of antioxidant defense mechanisms. It also provides useful information on gene modulation, radiation-generated reactive oxygen species-induced apoptosis in cancer, and environmental aspects associated with free radicals’ exposure on living systems.

Free Radicals and Oxidation Phenomena in Biological Systems

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Author :
Publisher : CRC Press
ISBN 13 : 9780824795870
Total Pages : 292 pages
Book Rating : 4.7/5 (958 download)

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Book Synopsis Free Radicals and Oxidation Phenomena in Biological Systems by : Roberfroid

Download or read book Free Radicals and Oxidation Phenomena in Biological Systems written by Roberfroid and published by CRC Press. This book was released on 1994-12-14 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work offers an analysis of the biological processes mediated by free radicals, from a toxicological point of view, providing easy access to information in an integrated, coherent presentation. The chemistry and biochemistry of all principal types of radical are explained, and the multiple forms in whch radicals participate in living organisms are investigated.;This work should be of use to biochemists, pharmacologists, pharmaceutical researchers, food scientists and technologists, nutritionists, toxicologists, chemists, biologists and graduate students in these disciplines.

Encyclopedia of Radicals in Chemistry, Biology, and Materials

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Author :
Publisher :
ISBN 13 :
Total Pages : 2293 pages
Book Rating : 4.:/5 (21 download)

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Book Synopsis Encyclopedia of Radicals in Chemistry, Biology, and Materials by :

Download or read book Encyclopedia of Radicals in Chemistry, Biology, and Materials written by and published by . This book was released on 2012 with total page 2293 pages. Available in PDF, EPUB and Kindle. Book excerpt: "In recent years, free radicals have played an important role in various disciplines, ranging from organic synthesis to biology and medicine, polymer chemistry and materials science. The aim of this handbook is to offer for the first time a description of free radicals within an interdisciplinary and multidisciplinary context, connecting structural characteristics and chemical properties to their applications in different areas of chemistry and related disciplines. The Handbook covers not only basic concepts and chemical synthesis, but also touches on various aspects concerning the role of free radicals in materials and life sciences. The reader will find a balanced contribution of topics related to free radicals covering for example, their role in proteomics, genomics and lipidomics as well as their enormous potential in synthesis and technology. The Handbook will be interesting for anybody working in the field of free radicals in the broadest sense. It will address scientists who want to enter the interdisciplinary field of free radicals. In particular, it is aimed primarily at chemists and life science researchers who want to gain a wider and deeper understanding of free radicals which will allow them to apply free radicals in their own scientific field. The book consists of four themed volumes: Basic Concepts & Methodologies, Synthetic Strategies & Applications, Chemical Biology, Polymers & Materials. Within the volumes the chapters will also be thematically structured"--

Free Radicals in Chemistry and Biology

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Author :
Publisher : CRC Press
ISBN 13 : 9780849353871
Total Pages : 322 pages
Book Rating : 4.3/5 (538 download)

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Book Synopsis Free Radicals in Chemistry and Biology by : Milan Lazar

Download or read book Free Radicals in Chemistry and Biology written by Milan Lazar and published by CRC Press. This book was released on 1989-03-31 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Elementary radical reactions are described in terms of fundamental knowledge of organic chemistry and chemical physics in this valuable reference text. The complex radical processes of nonchain and chain mechanisms, such as dimerization, alkylation, polymerization, telomerization, halogenation pyrolysis, oxidation and combustion, are complemented by reactions in chemical lasers and in the cosmos, as well as by reactions in biological objects under normal or pathological metabolism. The text also provides the synthesis of facts from various fields of research and involves mechanisms where free radicals appear either as main or side intermediates in one of the several alternatives of the reaction pathway. Highlights include 38 tables and 39 figures.

Power, Sex, Suicide

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Publisher : OUP Oxford
ISBN 13 : 9780191513015
Total Pages : 370 pages
Book Rating : 4.5/5 (13 download)

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Book Synopsis Power, Sex, Suicide by : Nick Lane

Download or read book Power, Sex, Suicide written by Nick Lane and published by OUP Oxford. This book was released on 2005-10-13 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondria are tiny structures located inside our cells that carry out the essential task of producing energy for the cell. They are found in all complex living things, and in that sense, they are fundamental for driving complex life on the planet. But there is much more to them than that. Mitochondria have their own DNA, with their own small collection of genes, separate from those in the cell nucleus. It is thought that they were once bacteria living independent lives. Their enslavement within the larger cell was a turning point in the evolution of life, enabling the development of complex organisms and, closely related, the origin of two sexes. Unlike the DNA in the nucleus, mitochondrial DNA is passed down exclusively (or almost exclusively) via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to 'Mitochondrial Eve'. Mitochondria give us important information about our evolutionary history. And that's not all. Mitochondrial genes mutate much faster than those in the nucleus because of the free radicals produced in their energy-generating role. This high mutation rate lies behind our ageing and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer, through their involvement in precipitating cell suicide. Mitochondria, then, are pivotal in power, sex, and suicide. In this fascinating and thought-provoking book, Nick Lane brings together the latest research findings in this exciting field to show how our growing understanding of mitochondria is shedding light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. This understanding is of fundamental importance, both in understanding how we and all other complex life came to be, but also in order to be able to control our own illnesses, and delay our degeneration and death. 'An extraordinary account of groundbreaking modern science... The book abounds with interesting and important ideas.' Mark Ridley, Department of Zoology, University of Oxford

Free Radicals in Biology and Medicine

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Author :
Publisher : IOS Press
ISBN 13 : 9781586036836
Total Pages : 286 pages
Book Rating : 4.0/5 (368 download)

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Book Synopsis Free Radicals in Biology and Medicine by : Okezie I. Aruoma

Download or read book Free Radicals in Biology and Medicine written by Okezie I. Aruoma and published by IOS Press. This book was released on 2006-10 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focuses on the pivotal roles of reactive oxygen and nitrogen species (ROS and RNS) in the pathogenesis of many clinical conditions (together with their involvement in the ageing process of lower (yeast) cells, and higher organisms including plants). This book also discusses the potential applications of dietary-derived antioxidants.

Free Radical Reactions in Medicine

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Publisher : Springer Science & Business Media
ISBN 13 : 3642831044
Total Pages : 300 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Free Radical Reactions in Medicine by : Janos Feher

Download or read book Free Radical Reactions in Medicine written by Janos Feher and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to provide a concise review of the medical aspects of free radical reactions. Until now, there have been extensive reviews of the subject in a physiological, pathophysiological and biochemical context. Here, however, the authors concentrate on the biology of free radical reactions as relevant to medical practice, emphasizing that the topic is not just a branch of basic science. Consequently, a short introduction on chemical and biological aspects is followed by a detailed discussion of the role played by free radical reactions in the pathogenesis and development of several human diseases and in therapeutic possibilities. The summary of data from the literature is supplemented by the authors' own experimental results. The presentation will help medical researchers to notice so far unknown connections among several diseases and to make them aware of the existance of the so-called "free radical diseases".

Encyclopedia of Radicals in Chemistry, Biology and Materials

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Author :
Publisher : Wiley
ISBN 13 : 9780470971253
Total Pages : 2324 pages
Book Rating : 4.9/5 (712 download)

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Book Synopsis Encyclopedia of Radicals in Chemistry, Biology and Materials by : Chryssostomos Chatgilialoglu

Download or read book Encyclopedia of Radicals in Chemistry, Biology and Materials written by Chryssostomos Chatgilialoglu and published by Wiley. This book was released on 2012-02-20 with total page 2324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Highlighting the growing applications of free radicals in key chemical, biological and medical processes Over the last two decades the application of free radicals in organic synthesis, materials science and life science has steadily increased, this Encyclopedia presents methodologies and mechanisms involving free radicals of chemical and biological research, including applications in materials science and medicine. The aim of this Encyclopedia is to offer for the first time a description of free radicals within an interdisciplinary and multidisciplinary context, connecting structural characteristics and chemical properties to their applications in different areas of chemistry and related disciplines. It covers not only basic concepts and chemical synthesis, but also touches on various aspects concerning the role of free radicals in materials and life sciences. The reader will find a balanced contribution of topics related to free radicals covering for example, their role in proteomics, genomics and lipidomics as well as their enormous potential in synthesis and technology. Covers topical areas such as: Alzheimer's disease and antioxidants in food within medicine and life sciences Synthesis and catalysis, combustion and atmospheric chemistry within chemistry Ageing and signalling in biological processes Of interest to anybody working in the field of free radicals in the broadest sense. It will address scientists who want to enter the interdisciplinary field of free radicals. In particular, it is aimed primarily at chemists and life science researchers who want to gain a wider and deeper understanding of free radicals which will allow them to apply free radicals in their own scientific field. The book consists of four themed volumes: Basic Concepts & Methodologies Synthetic Strategies & Applications Chemical Biology Polymers & Materials Online Edition Encyclopedia of Radicals in Chemistry, Biology and Materials is also available online, click here for more details: http://onlinelibrary.wiley.com/book/10.1002/9781119953678

Free Radicals, Antioxidants and Diseases

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Publisher : BoD – Books on Demand
ISBN 13 : 1789235642
Total Pages : 150 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Free Radicals, Antioxidants and Diseases by : Rizwan Ahmad

Download or read book Free Radicals, Antioxidants and Diseases written by Rizwan Ahmad and published by BoD – Books on Demand. This book was released on 2018-08-01 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: The current book entitled Free Radicals, Antioxidants, and Diseases gives an idea of detecting free radicals in vivo by newer techniques and provides insights into the roles played by various antioxidants in combating diseases caused by oxidative stress. The chapters included in this volume showcase new investigation in this field by the research groups around the world.

Free Radicals and Iron

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Publisher :
ISBN 13 :
Total Pages : 262 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Free Radicals and Iron by : Martyn C. R. Symons

Download or read book Free Radicals and Iron written by Martyn C. R. Symons and published by . This book was released on 1998 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: This concise monograph describes a variety of important reactions of iron in biological free-radical reactions. It presents both a chemical and a biochemical perspective of the topic, but at the same time unifies ideas where possible. Iron plays a key role in biological life processes, as acatalayst enabling us to use oxygen to generate the heat and chemical energy that drives life. When iron is not properly controlled within the body it can cause damage by making free radicals. The authors present a chemical and biomedical perspective of how reactions of iron complexes and freeradicals may contribute to human health and disease, especially in reactions of oxygen and hydrogen peroxide.

Free Radicals in Synthesis and Biology

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Author :
Publisher : Springer
ISBN 13 :
Total Pages : 512 pages
Book Rating : 4.:/5 (44 download)

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Book Synopsis Free Radicals in Synthesis and Biology by : F. Minisci

Download or read book Free Radicals in Synthesis and Biology written by F. Minisci and published by Springer. This book was released on 1989 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the NATO Advanced Research Workshop, Bardolino (VR), Italy, May 8-13, 1988