Formal Methods for the Analysis of Biomedical Ontologies

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Publisher : Springer Nature
ISBN 13 : 3031121317
Total Pages : 258 pages
Book Rating : 4.0/5 (311 download)

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Book Synopsis Formal Methods for the Analysis of Biomedical Ontologies by : Guo-Qiang Zhang

Download or read book Formal Methods for the Analysis of Biomedical Ontologies written by Guo-Qiang Zhang and published by Springer Nature. This book was released on 2022-11-08 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book synthesizes research on the analysis of biomedical ontologies using formal concept analysis, including through auditing, curation, and enhancement. As the evolution of biomedical ontologies almost inevitably involves manual work, formal methods are a particularly useful tool for ontological engineering and practice, particularly in uncovering unexpected "bugs" and content materials. The book first introduces simple but formalized strategies for discovering undesired and incoherent patterns in ontologies before exploring the application of formal concept analysis for semantic completeness. The book then turns to formal concept analysis, a classical approach used in the mathematical treatment of orders and lattices, as an ontological engineering principle, focusing on the structural property of ontologies with respect to its conformation to lattice or not (non-lattice). The book helpfully covers the development of more efficient algorithms for non-lattice detection and extraction required by exhaustive lattice/non-lattice analysis. The book goes on to highlight the power and utility of uncovering non-lattice structure for debugging ontologies and describes methods that leverage the linguistic information in concept names (labels) for ontological analysis. It also addresses visualization and performance evaluation issues before closing with an overview and forward-looking perspectives on the field. This book is intended for graduate students and researchers interested in biomedical ontologies and their applications. It can be a useful supplement for courses on knowledge representation and engineering and also provide readers with a reference for related scientific publications and literature to assist in identifying potential research topics. All mathematical concepts and notations used in this book can be found in standard discrete mathematics textbooks, and the appendix at the end of the book provides a list of key ontological resources, as well as annotated non-lattice and lattice examples that were discovered using the authors' methods, demonstrating how "bugs are fixed" by converting non-lattices to lattices with minimal edit changes.

Leveraging Applications of Formal Methods, Verification and Validation. Specialized Techniques and Applications

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Publisher : Springer
ISBN 13 : 3662452316
Total Pages : 661 pages
Book Rating : 4.6/5 (624 download)

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Book Synopsis Leveraging Applications of Formal Methods, Verification and Validation. Specialized Techniques and Applications by : Tiziana Margaria

Download or read book Leveraging Applications of Formal Methods, Verification and Validation. Specialized Techniques and Applications written by Tiziana Margaria and published by Springer. This book was released on 2014-09-26 with total page 661 pages. Available in PDF, EPUB and Kindle. Book excerpt: The two-volume set LNCS 8802 and LNCS 8803 constitutes the refereed proceedings of the 6th International Symposium on Leveraging Applications of Formal Methods, Verification and Validation, ISoLA 2014, held in Imperial, Corfu, Greece, in October 2014. The total of 67 full papers was carefully reviewed and selected for inclusion in the proceedings. Featuring a track introduction to each section, the papers are organized in topical sections named: evolving critical systems; rigorous engineering of autonomic ensembles; automata learning; formal methods and analysis in software product line engineering; model-based code generators and compilers; engineering virtualized systems; statistical model checking; risk-based testing; medical cyber-physical systems; scientific workflows; evaluation and reproducibility of program analysis; processes and data integration in the networked healthcare; semantic heterogeneity in the formal development of complex systems. In addition, part I contains a tutorial on automata learning in practice; as well as the preliminary manifesto to the LNCS Transactions on the Foundations for Mastering Change with several position papers. Part II contains information on the industrial track and the doctoral symposium and poster session.

Formal Methods for Managing and Processing Ontology Alignments

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Publisher : CRC Press
ISBN 13 : 1040133274
Total Pages : 210 pages
Book Rating : 4.0/5 (41 download)

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Book Synopsis Formal Methods for Managing and Processing Ontology Alignments by : Marcin Pietranik

Download or read book Formal Methods for Managing and Processing Ontology Alignments written by Marcin Pietranik and published by CRC Press. This book was released on 2024-10-07 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ontologies are formal knowledge representation methods that can provide means for a shared understanding of a given domain. To enable meaningful communication and interoperability between two or more information systems that utilize independently created ontologies, a bridge between them is necessary, often referred to as an ontology alignment. Formal Methods for Managing and Processing Ontology Alignments provides complete ontology alignment lifecycle, including modelling, methods, and maintenance processes. Summarizing the author's research from the past ten years, this book consolidates findings previously published in prestigious international journals and presented at leading conferences. Each chapter is designed to be self-contained, allowing readers to approach the material modularly. The text introduces basic mathematical concepts, and later chapters build upon these foundations, but each focuses on specific aspects of ontology alignment, making the content accessible and easy to follow. Key Features Includes formal definitions of ontologies and ontology alignment along with a set of methods for providing semantics of attributes and relations. Provides application of fuzzy logic in the task of ontology alignment. Contains methods of managing the evolution of ontologies and their alignments. Proposes novel methods of assessing the quality ontology alignment. Situated in the fields of knowledge representation and semantic technologies, this book is an invaluable resource for both academic researchers and practitioners, as well as students looking to deepen their understanding.

Implicit and Explicit Semantics Integration in Proof-Based Developments of Discrete Systems

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Publisher : Springer Nature
ISBN 13 : 9811550549
Total Pages : 345 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Implicit and Explicit Semantics Integration in Proof-Based Developments of Discrete Systems by : Yamine Ait-Ameur

Download or read book Implicit and Explicit Semantics Integration in Proof-Based Developments of Discrete Systems written by Yamine Ait-Ameur and published by Springer Nature. This book was released on 2020-07-27 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses mechanisms for reducing model heterogeneity induced by the absence of explicit semantics expression in the formal techniques used to specify design models. More precisely, it highlights the advances in handling both implicit and explicit semantics in formal system developments, and discusses different contributions expressing different views and perceptions on the implicit and explicit semantics. The book is based on the discussions at the Shonan meeting on this topic held in 2016, and includes contributions from the participants summarising their perspectives on the problem and offering solutions. Divided into 5 parts: domain modelling, knowledge-based modelling, proof-based modelling, assurance cases, and refinement-based modelling, and offers inspiration for researchers and practitioners in the fields of formal methods, system and software engineering, domain knowledge modelling, requirement analysis, and explicit and implicit semantics of modelling languages.

Leveraging Applications of Formal Methods, Verification and Validation. Technologies for Mastering Change

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Author :
Publisher : Springer
ISBN 13 : 3662452340
Total Pages : 564 pages
Book Rating : 4.6/5 (624 download)

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Book Synopsis Leveraging Applications of Formal Methods, Verification and Validation. Technologies for Mastering Change by : Tiziana Margaria

Download or read book Leveraging Applications of Formal Methods, Verification and Validation. Technologies for Mastering Change written by Tiziana Margaria and published by Springer. This book was released on 2014-09-26 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: The two-volume set LNCS 8802 and LNCS 8803 constitutes the refereed proceedings of the 6th International Symposium on Leveraging Applications of Formal Methods, Verification and Validation, ISoLA 2014, held in Imperial, Corfu, Greece, in October 2014. The total of 67 full papers was carefully reviewed and selected for inclusion in the proceedings. Featuring a track introduction to each section, the papers are organized in topical sections named: evolving critical systems; rigorous engineering of autonomic ensembles; automata learning; formal methods and analysis in software product line engineering; model-based code generators and compilers; engineering virtualized systems; statistical model checking; risk-based testing; medical cyber-physical systems; scientific workflows; evaluation and reproducibility of program analysis; processes and data integration in the networked healthcare; semantic heterogeneity in the formal development of complex systems. In addition, part I contains a tutorial on automata learning in practice; as well as the preliminary manifesto to the LNCS Transactions on the Foundations for Mastering Change with several position papers. Part II contains information on the industrial track and the doctoral symposium and poster session.

Formal Ontology in Information Systems

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Author :
Publisher : IOS Press
ISBN 13 : 1586039237
Total Pages : 340 pages
Book Rating : 4.5/5 (86 download)

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Book Synopsis Formal Ontology in Information Systems by : Carola Eschenbach

Download or read book Formal Ontology in Information Systems written by Carola Eschenbach and published by IOS Press. This book was released on 2008 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Since its start ten years ago, the International Conference in Formal Ontology on Information Systems (FOIS) has explored the multiple perspectives on the notion of ontology that have arisen from such diverse research communities as philosophy, logic, computer science, cognitive science, linguistics, and various scientific domains. As ontologies have been applied in new and exciting domains such as the World Wide Web, bioinformatics, and geographical information systems, it has become evident that there is a need for ontologies that have been developed with solid theoretical foundations based on philosophical, linguistic and logical analysis. Similarly, there is also a need for theoretical research that is driven by the issues that have been raised by recent work in the more applied domains. FOIS is intended to be a forum in which to explore this interplay between the theoretical insights of formal ontology and their application to information systems and emerging semantic technologies. Themes emerging from this volume give a snapshot of current issues within the fields of formal ontology and ontological engineering, as well providing a glimpse of future research directions."--BOOK JACKET.

Formal Concept Analysis

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Publisher : Springer Science & Business Media
ISBN 13 : 3642018149
Total Pages : 350 pages
Book Rating : 4.6/5 (42 download)

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Book Synopsis Formal Concept Analysis by : Sébastien Ferré

Download or read book Formal Concept Analysis written by Sébastien Ferré and published by Springer Science & Business Media. This book was released on 2009-05-12 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 7th International Conference on Formal Concept Analysis, ICFCA 2009, held in Darmstadt, Germany, in May 2009. The 15 revised full papers presented were carefully reviewed and selected from 29 submissions for inclusion in the book. The papers comprise state of the art research and present new results in Formal Concept Analysis and related fields. These results range from theoretical novelties to advances in FCA-related algorithmic issues, as well as application domains of FCA such as data visualization, information retrieval, machine learning, data analysis and knowledge management.

Foundations of Biomedical Knowledge Representation

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Publisher : Springer
ISBN 13 : 3319280074
Total Pages : 336 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Foundations of Biomedical Knowledge Representation by : Arjen Hommersom

Download or read book Foundations of Biomedical Knowledge Representation written by Arjen Hommersom and published by Springer. This book was released on 2016-01-07 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicine and health care are currently faced with a significant rise in their complexity. This is partly due to the progress made during the past three decades in the fundamental biological understanding of the causes of health and disease at the molecular, (sub)cellular, and organ level. Since the end of the 1970s, when knowledge representation and reasoning in the biomedical field became a separate area of research, huge progress has been made in the development of methods and tools that are finally able to impact on the way medicine is being practiced. Even though there are huge differences in the techniques and methods used by biomedical researchers, there is now an increasing tendency to share research results in terms of formal knowledge representation methods, such as ontologies, statistical models, network models, and mathematical models. As there is an urgent need for health-care professionals to make better decisions, computer-based support using this knowledge is now becoming increasingly important. It may also be the only way to integrate research results from the different parts of the spectrum of biomedical and clinical research. The aim of this book is to shed light on developments in knowledge representation at different levels of biomedical application, ranging from human biology to clinical guidelines, and using different techniques, from probability theory and differential equations to logic. The book starts with two introductory chapters followed by 18 contributions organized in the following topical sections: diagnosis of disease; monitoring of health and disease and conformance; assessment of health and personalization; prediction and prognosis of health and disease; treatment of disease; and recommendations.

Formal Ontologies Meet Industry

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Publisher : IOS Press
ISBN 13 : 1607504588
Total Pages : 144 pages
Book Rating : 4.6/5 (75 download)

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Book Synopsis Formal Ontologies Meet Industry by : R. Ferrario

Download or read book Formal Ontologies Meet Industry written by R. Ferrario and published by IOS Press. This book was released on 2009-08-21 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a collection of papers addressing the multi-shaped character of knowledge, new studies and applications in the field of ontology and semantic technology. The semantic dimension of information plays an increasingly central role in a networked, knowledge-centred economy and the need to encode information into computer systems has led to a bias towards Knowledge Engineering (KE) solutions as opposed to Knowledge Management (KM). Although the intersection between KE and KM has led to a general improvement of information systems, the overlap between these two fields has tended to eclipse interest in genuine knowledge processes. For this reason, the fourth FOMI workshop was held to coincide with the 10th European Conference of Knowledge Management (ECKM), with the explicit aim of bringing together KR and KM (sub)-communities, providing a platform for discussion of these topics. Subjects covered include: the evolution of ontologies in accordance with the evolution of the domain they are designed for; the study of the notions of functional composition and decomposition; modular ontologies for architecture; ontology infrastructure for electromagnetics; ontology of beliefs; enterprise modelling; the application of ontology-based methodologies and techniques to knowledge management issues; ontologies for standards and domain ontologies for biomedicine. The double focus on methodological and applicative issues represents the main feature of these FOMI 2009 articles. This comprehensive perspective will advance progress towards new frontiers in information systems and knowledge management, where research and development in formal ontology will play a leading role.

Building Ontologies with Basic Formal Ontology

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Publisher : MIT Press
ISBN 13 : 0262527812
Total Pages : 245 pages
Book Rating : 4.2/5 (625 download)

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Book Synopsis Building Ontologies with Basic Formal Ontology by : Robert Arp

Download or read book Building Ontologies with Basic Formal Ontology written by Robert Arp and published by MIT Press. This book was released on 2015-07-31 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to the field of applied ontology with examples derived particularly from biomedicine, covering theoretical components, design practices, and practical applications. In the era of “big data,” science is increasingly information driven, and the potential for computers to store, manage, and integrate massive amounts of data has given rise to such new disciplinary fields as biomedical informatics. Applied ontology offers a strategy for the organization of scientific information in computer-tractable form, drawing on concepts not only from computer and information science but also from linguistics, logic, and philosophy. This book provides an introduction to the field of applied ontology that is of particular relevance to biomedicine, covering theoretical components of ontologies, best practices for ontology design, and examples of biomedical ontologies in use. After defining an ontology as a representation of the types of entities in a given domain, the book distinguishes between different kinds of ontologies and taxonomies, and shows how applied ontology draws on more traditional ideas from metaphysics. It presents the core features of the Basic Formal Ontology (BFO), now used by over one hundred ontology projects around the world, and offers examples of domain ontologies that utilize BFO. The book also describes Web Ontology Language (OWL), a common framework for Semantic Web technologies. Throughout, the book provides concrete recommendations for the design and construction of domain ontologies.

Formal Ontology in Information Systems

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Publisher : IOS Press
ISBN 13 : 1607505347
Total Pages : 444 pages
Book Rating : 4.6/5 (75 download)

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Book Synopsis Formal Ontology in Information Systems by : Antony Galton

Download or read book Formal Ontology in Information Systems written by Antony Galton and published by IOS Press. This book was released on 2010 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ontology began life in ancient times as a fundamental part of philosophical enquiry concerned with the analysis and categorisation of what exists. In recent years, the subject has taken a practical turn with the advent of complex computerised information systems which are reliant on robust and coherent representations of their subject matter. The systematisation and elaboration of such representations and their associated reasoning techniques constitute the modern discipline of formal ontology, which is now being applied to such diverse domains as artificial intelligence, computational linguistics, bioinformatics, GIS, knowledge engineering, information retrieval and the Semantic Web. Researchers in all these areas are becoming increasingly aware of the need for serious engagement with ontology, understood as a general theory of the types of entities and relations making up their respective domains of enquiry, to provide a solid foundation for their work. The conference series Formal Ontology in Information Systems (FOIS) provides a meeting point for researchers from these and other disciplines with an interest in formal ontology, where both theoretical issues and concrete applications can be explored in a spirit of genuine interdisciplinarity. This volume contains the proceedings of the sixth FOIS conference, held in Toronto, Canada, during 11-14 May 2010, including invited talks by Francis Jeffry Pelletier, John Bateman, and Alan Rector and the 28 peer-reviewed submissions selected for presentation at the conference, ranging from foundational issues to more application-oriented topics. IOS Press is an international science, technical and medical publisher of high-quality books for academics, scientists, and professionals in all fields. Some of the areas we publish in: -Biomedicine -Oncology -Artificial intelligence -Databases and information systems -Maritime engineering -Nanotechnology -Geoengineering -All aspects of physics -E-governance -E-commerce -The knowledge economy -Urban studies -Arms control -Understanding and responding to terrorism -Medical informatics -Computer Sciences

Formal Verification of Tree Ensembles in Safety-Critical Applications

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Author :
Publisher : Linköping University Electronic Press
ISBN 13 : 917929748X
Total Pages : 22 pages
Book Rating : 4.1/5 (792 download)

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Book Synopsis Formal Verification of Tree Ensembles in Safety-Critical Applications by : John Törnblom

Download or read book Formal Verification of Tree Ensembles in Safety-Critical Applications written by John Törnblom and published by Linköping University Electronic Press. This book was released on 2020-10-28 with total page 22 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the presence of data and computational resources, machine learning can be used to synthesize software automatically. For example, machines are now capable of learning complicated pattern recognition tasks and sophisticated decision policies, two key capabilities in autonomous cyber-physical systems. Unfortunately, humans find software synthesized by machine learning algorithms difficult to interpret, which currently limits their use in safety-critical applications such as medical diagnosis and avionic systems. In particular, successful deployments of safety-critical systems mandate the execution of rigorous verification activities, which often rely on human insights, e.g., to identify scenarios in which the system shall be tested. A natural pathway towards a viable verification strategy for such systems is to leverage formal verification techniques, which, in the presence of a formal specification, can provide definitive guarantees with little human intervention. However, formal verification suffers from scalability issues with respect to system complexity. In this thesis, we investigate the limits of current formal verification techniques when applied to a class of machine learning models called tree ensembles, and identify model-specific characteristics that can be exploited to improve the performance of verification algorithms when applied specifically to tree ensembles. To this end, we develop two formal verification techniques specifically for tree ensembles, one fast and conservative technique, and one exact but more computationally demanding. We then combine these two techniques into an abstraction-refinement approach, that we implement in a tool called VoTE (Verifier of Tree Ensembles). Using a couple of case studies, we recognize that sets of inputs that lead to the same system behavior can be captured precisely as hyperrectangles, which enables tractable enumeration of input-output mappings when the input dimension is low. Tree ensembles with a high-dimensional input domain, however, seems generally difficult to verify. In some cases though, conservative approximations of input-output mappings can greatly improve performance. This is demonstrated in a digit recognition case study, where we assess the robustness of classifiers when confronted with additive noise.

Business Systems Analysis with Ontologies

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Publisher : IGI Global
ISBN 13 : 1591403413
Total Pages : 378 pages
Book Rating : 4.5/5 (914 download)

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Book Synopsis Business Systems Analysis with Ontologies by : Green, Peter F.

Download or read book Business Systems Analysis with Ontologies written by Green, Peter F. and published by IGI Global. This book was released on 2005-03-31 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book shows systems analysts and business analysts how ontological thinking can help them clarify requirements analysis tasks in business systems"--Provided by publisher.

Ontologies in Medicine

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Publisher : IOS Press
ISBN 13 : 9781586034184
Total Pages : 186 pages
Book Rating : 4.0/5 (341 download)

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Book Synopsis Ontologies in Medicine by : Domenico M. Pisanelli

Download or read book Ontologies in Medicine written by Domenico M. Pisanelli and published by IOS Press. This book was released on 2004 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Title Page -- Contents -- If Ontology is the Solution, What is the Problem? -- Biodynamic Ontology: Applying BFO in the Biomedical Domain -- Bodily Systems and the Spatial-Functional Structure of the Human Body -- Inflammation Ontology Design Pattern: An Exercise in Building a Core Biomedical Ontology With Descriptions and Situations -- Context-Based Task Ontologies for Clinical Guidelines -- An Ontological Framework for the Implementation of Clinical Guidelines in Health Care Organizations -- Gene Ontology Application to Genomic Functional Annotation, Statistical Analysis and Knowledge Mining -- Evolving from Standard Vocabularies to Formal Ontology for an Information System Dedicated to Organ Transplantation -- Mistakes in Medical Ontologies: Where Do They Come From and How Can They Be Detected? -- Author Index

Formal Ontology in Information Systems

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Publisher : IOS Press
ISBN 13 : 1614996601
Total Pages : 392 pages
Book Rating : 4.6/5 (149 download)

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Book Synopsis Formal Ontology in Information Systems by : R. Ferrario

Download or read book Formal Ontology in Information Systems written by R. Ferrario and published by IOS Press. This book was released on 2016-07-06 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ontology, originally a fundamental part of philosophical enquiry, is concerned with the analysis and categorization of what exists. The advent of complex information systems which rely on robust and coherent formal representations of their subject matter has led to a renewed focus on ontological enquiry, and the systematic study of such representations are at the center of the modern discipline of formal ontology. This is now a research focus in domains as diverse as conceptual modeling, database design, software engineering, artificial intelligence, computational linguistics, the life sciences, bioinformatics, geographic information science, knowledge engineering, information retrieval and the semantic web. This book presents the proceedings of the 9th edition of the Formal Ontology in Information Systems conference (FOIS 2016) held in Annecy, France, in July 2016. It contains the 25 full papers delivered at the conference (an acceptance rate of 30.9% for the main track), as well as the abstracts of the 3 keynotes by Gilberto Câmara, Stephen Mumford and Friederike Moltmann. The remainder of the book is divided into the sections: Foundations; Space, Time and Change; Cognition, Language and Semantics; Empiricism and Measurement; Ontology for Engineering; Biomedical Ontologies; and Ontology of Social Reality. The domains addressed by the papers include geography, biomedicine, economics, social reality and engineering, and the book will be of interest to all those working in these fields, as well as to anybody with an interest in formal ontology.

Computation, Information, Cognition

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Publisher : Cambridge Scholars Publishing
ISBN 13 : 1443809322
Total Pages : 380 pages
Book Rating : 4.4/5 (438 download)

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Book Synopsis Computation, Information, Cognition by : Gordana Dodig Crnkovic

Download or read book Computation, Information, Cognition written by Gordana Dodig Crnkovic and published by Cambridge Scholars Publishing. This book was released on 2009-03-26 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book draws together a number of important strands in contemporary approaches to the philosophical and scientific questions that emerge when dealing with the issues of computing, information, cognition and the conceptual issues that arise at their intersections. It discovers and develops the connections at the borders and in the interstices of disciplines and debates, and presents a range of essays that deal with the currently vigorous concerns of the philosophy of information, ontology creation and control, bioinformation and biosemiotics, computational and post- computational ap- proaches to the philosophy of cognitive science, computational linguistics, ethics, and education.

Formal Ontology in Information Systems

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Author :
Publisher : IOS Press
ISBN 13 : 1614990832
Total Pages : 368 pages
Book Rating : 4.6/5 (149 download)

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Book Synopsis Formal Ontology in Information Systems by : Maureen Donnelly

Download or read book Formal Ontology in Information Systems written by Maureen Donnelly and published by IOS Press. This book was released on 2012 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: The complex information systems which have evolved in recent decades rely on robust and coherent representations in order to function. Such representations and associated reasoning techniques constitute the modern discipline of formal ontology, which is now applied to fields such as artificial intelligence, computational linguistics, bioinformatics, GIS, conceptual modeling, knowledge engineering, information retrieval, and the semantic web. Ontologies are increasingly employed in a number of complex real-world application domains. For instance, in biology and medicine, more and more principle-based ontologies are being developed for the description of biological and biomedical phenomena. To be effective, such ontologies must work well together, and as they become more widely used, achieving coordinated development presents a significant challenge. This book presents collected articles from the 7th International Conference on Formal Ontologies (FOIS), held in Graz, Austria, in July 2012.FOIS is a forum which brings together representatives of all major communities involved in the development and application of ontologies to explore both theoretical issues and concrete applications in the field. The book is organized in eight sections, each of which deals with the ontological aspects of: bioinformatics; physical entities; artifacts and human resources; ontology evaluation; language and social relations; time and events; representation and the methodological aspects of ontological engineering. Providing a current overview of developments in formal ontology, this book will be of interest to all those whose work involves the application of ontologies, and to anybody wishing to keep abreast of advances in the field.