Fatty Acid Binding Proteins And Their Roles In Human Health And Disease

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Cellular Proteins and Their Fatty Acids in Health and Disease

Author : Asim K. Duttaroy
Publisher : John Wiley & Sons
ISBN 13 : 3527605282
Total Pages : 478 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Cellular Proteins and Their Fatty Acids in Health and Disease by : Asim K. Duttaroy

Download or read book Cellular Proteins and Their Fatty Acids in Health and Disease written by Asim K. Duttaroy and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: In light of the increasing importance of these proteins and their ligands for our understanding of cellular growth, differentiation, and development, as well as of diseases such as obesity, insulin resistance, atherosclerosis, cancer, and inflammation, a team of internationally renowned editors and authors have compiled here the very first comprehensive book on these topics. They describe fatty acid-activated transcription factors as well as membrane and soluble fatty acid transporters, covering such aspects as structure and function, lipid-protein interaction, delivery of ligands, and the roles of these proteins in gene expression pertaining to the homeostatic and diseased states of cells and organs. Incorporating recent findings, this is indispensable for basic scientists, health professionals in industry and clinics as well as postgraduate students. Contributors among others: N.A. Abumrad, J.E. Schaffer, G. Schmitz, N.J. Brunskill, J. Storch, U. Seedorf, S. Mandrup, C.N.A. Palmer, T. Perlmann, H.I. Nebb, J. Bar-Tana, H. Kondo, C. Wolfrum, C. Kerkhoff , S. Farmer, E.J. Murphy, J.F.C. Glatz, P. Besnard, J.M. Stewart, A. Meirhaeghe, J. Plutzky, W. Wahli, R.A. Roberts

Fatty Acid-Binding Proteins and Their Roles in Human Health and Disease

Author : Asim K. Duttaroy
Publisher : Elsevier
ISBN 13 : 0323957013
Total Pages : 426 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Fatty Acid-Binding Proteins and Their Roles in Human Health and Disease by : Asim K. Duttaroy

Download or read book Fatty Acid-Binding Proteins and Their Roles in Human Health and Disease written by Asim K. Duttaroy and published by Elsevier. This book was released on 2024-08-06 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fatty Acid-Binding Proteins and Their Roles in Human Health and Disease: From Basic Science to Clinical Application presents the latest information on the contributions of different FABPs in physiology and pathophysiology, along with their importance in clinical outcomes. The book is divided into six main sections that cover FABP biology and their role in inflammation and diseases, such as cardiovascular, neurological, and liver diseases, to FABPs and their clinical applications. Each chapter thoroughly reviews current literature, primary research data and clinical cases, providing readers with an overview of the latest information in the expanded field of FABPs. This is an invaluable resource for both researchers and clinicians familiar with and those new to the exciting and everchanging world of fatty acid-binding proteins and clinical disorders. - Compiles the most recent and comprehensive findings on fatty acid-binding proteins (FABPs) - Describes the pathophysiology of FABPs in various diseases and as therapeutic targets - Highlights opportunities for improving diagnosis and treatment by encompassing all pathological conditions involving FABPs

Free Fatty Acid Receptors

Author : Graeme Milligan
Publisher : Springer
ISBN 13 : 3319506935
Total Pages : 258 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Free Fatty Acid Receptors by : Graeme Milligan

Download or read book Free Fatty Acid Receptors written by Graeme Milligan and published by Springer. This book was released on 2017-02-08 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the important role free fatty acids (FFA) play as potential drug targets. While FFA have long been considered byproducts of cell metabolism, they are now recognized as ligands that regulate cell and tissue function via G-protein-coupled receptors. At least three receptors have been identified for which FFA appear to be the endogenous ligands.

Diet and Health

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309039940
Total Pages : 765 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Diet and Health by : National Research Council

Download or read book Diet and Health written by National Research Council and published by National Academies Press. This book was released on 1989-01-01 with total page 765 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.

Molecular Biology of the Cell

Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cardiac Metabolism in Health and Disease

Author : Salah Abdel-aleem
Publisher : Springer Science & Business Media
ISBN 13 : 1461556872
Total Pages : 192 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Cardiac Metabolism in Health and Disease by : Salah Abdel-aleem

Download or read book Cardiac Metabolism in Health and Disease written by Salah Abdel-aleem and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: This special issue of Molecular and Cellular Biochemistry contains original research papers as well as invited reviews focused in the field of cardiac metabolism and its regulation under normal and disease conditions. These papers cover many areas under intensive and rapid development such as the regulation of fatty acid oxidation in the heart, the role of cardiac glycogen during ischemia, the role of CPT I isoenzymes, the pathophysiology of diabetic cardiomyopathy, cardiac protection through regulation of energy production, the role of fatty acid binding protein under normal and pathological conditions, and several other important topics in this area of research. We hope that this special issue of Molecular and Cellular Biochemistry provides an up-to-date source of information for scientists and clinicians interested in the mechanism by which cardiac metabolism is regulated in health and disease and the mechanistic relationship between disturbances in cardiac metabolism and the genesis of cardiovascular diseases.

Polyunsaturated Fatty Acid Metabolism

Author : Graham C. Burdge
Publisher : Elsevier
ISBN 13 : 012811231X
Total Pages : 256 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Polyunsaturated Fatty Acid Metabolism by : Graham C. Burdge

Download or read book Polyunsaturated Fatty Acid Metabolism written by Graham C. Burdge and published by Elsevier. This book was released on 2018-05-04 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polyunsaturated Fatty Acid Metabolism explores a number of major roles of PUFA in the body, including its role as a component of cell membranes and how it provides substrates for the synthesis of lipid second messengers. Recent studies are unraveling the effect of interactions between diet and endocrine factors and genetic and epigenetic variation on the regulation of PUFA biosynthesis in animals. Together, these recent findings provide novel insights into the impact of differences in PUFA supply on health. This book captures these findings in a manner that marks the state-of-the-art, placing them in the wider context of PUFA metabolism and nutritional science. Users will find a comprehensive discussion on the topic that presents the contributions of leading researchers who combine their knowledge to create a cohesive academic resource for researchers, those involved in production, and health policymakers. - Provides a comprehensive view of polyunsaturated fatty acid metabolism - Describes underlying metabolism on lipids that include polyunsaturated fatty acids - Includes discussions on recent findings on the genetic and epigenetic regulation of polyunsaturated fatty acid metabolism

Omega Fatty Acids in Brain and Neurological Health

Author : Ronald Ross Watson
Publisher : Academic Press
ISBN 13 : 0128152397
Total Pages : 520 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Omega Fatty Acids in Brain and Neurological Health by : Ronald Ross Watson

Download or read book Omega Fatty Acids in Brain and Neurological Health written by Ronald Ross Watson and published by Academic Press. This book was released on 2019-06-12 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research has clearly established a link between omega fatty acids and general health, particularly cardiovascular health. Omega Fatty Acids in Brain and Neurological Health, Second Edition, illustrates the importance of omega-3 fatty acids in longevity, cognitive impairment and structure and function of the brain's neurons and also the adverse effects of omega-6 fatty acids on neurological function. This book encompasses some of the most recent research on the links between omega fatty acids and the developing brain, aging, dementia, Alzheimer's disease and multiple sclerosis, including the role of omega-3 fatty acid supplements on hippocampal neurogenesis, substantia nigra modulation, migraine headaches, the developing brain in animals, sleep and neurodegenerative diseases. This completely updated second edition focuses on the counterbalancing dietary and tissue omega-6 fatty acids as well as it studies the effects in pregnancy and early infancy, animal model studies and autoimmune neurological diseases. - Provides a comprehensive introduction to omega-3 and omega-6 fatty acids in neurological health and directions for future research - Features novel focus on the adverse effects of omega-6 fatty acids on neurological function and the counterbalancing of dietary and tissue omega-6 - Illustrates the importance of omega-3 fatty acids in longevity and cognitive impairment - Features new chapters on early effects in pregnancy and early infancy, animal model studies and autoimmune neurological diseases - Discusses links between omega fatty acids and the developing brain, aging, dementia, Alzheimer's disease and multiple sclerosis, including the role of omega-3 fatty acid supplements

Organelle Contact Sites

Author : Mitsuo Tagaya
Publisher : Springer
ISBN 13 : 9811045674
Total Pages : 254 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Organelle Contact Sites by : Mitsuo Tagaya

Download or read book Organelle Contact Sites written by Mitsuo Tagaya and published by Springer. This book was released on 2017-08-16 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the first comprehensive coverage of the quickly evolving research field of membrane contact sites (MCS). A total of 16 chapters explain their organization and role and unveil the significance of MCS for various diseases. MCS, the intracellular structures where organellar membranes come in close contact with one another, mediate the exchange of proteins, lipids, and ions. Via these functions, MCS are critical for the survival and the growth of the cell. Owing to that central role in the functioning of cells, MCS dysfunctions lead to important defects of human physiology, influence viral and bacterial infection, and cause disease such as inflammation, type II diabetes, neurodegenerative disorders, and cancer. To approach such a multifaceted topic, this volume assembles a series of chapters dealing with the full array of research about MCS and their respective roles for diseases. Most chapters also introduce the history and the state of the art of MCS research, which will initiate discussion points for the respective types of MCS for years to come. This work will appeal to all cell biologists as well as researchers on diseases that are impacted by MCS dysfunction. Additionally, it will stimulate graduate students and postdocs who will energize, drive, and develop the research field in the near future.

Fat Detection

Author : Jean-Pierre Montmayeur
Publisher : CRC Press
ISBN 13 : 1420067761
Total Pages : 646 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Fat Detection by : Jean-Pierre Montmayeur

Download or read book Fat Detection written by Jean-Pierre Montmayeur and published by CRC Press. This book was released on 2009-09-14 with total page 646 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the State-of-the-Art in Fat Taste TransductionA bite of cheese, a few potato chips, a delectable piece of bacon - a small taste of high-fat foods often draws you back for more. But why are fatty foods so appealing? Why do we crave them? Fat Detection: Taste, Texture, and Post Ingestive Effects covers the many factors responsible for the se

Adipose Tissue in Health and Disease

Author : Todd Leff
Publisher : John Wiley & Sons
ISBN 13 : 9783527629534
Total Pages : 530 pages
Book Rating : 4.6/5 (295 download)

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Book Synopsis Adipose Tissue in Health and Disease by : Todd Leff

Download or read book Adipose Tissue in Health and Disease written by Todd Leff and published by John Wiley & Sons. This book was released on 2010-03-19 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely and most comprehensive reference available on the topic covers all the different aspects vital in the fight against the global obesity epidemic. Following a look at adipose tissue development and morphology, the authors go on to examine its metabolic and endocrine functions and its role in disease. The final section deals with comparative and evolutionary aspects of the tissue. The result is an essential resource for cell and molecular biologists, physiologists, biochemists, pharmacologists, and those working in the pharmaceutical industry.

Current Topics in Membranes

Author :
Publisher : Academic Press
ISBN 13 : 0080585108
Total Pages : 477 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Current Topics in Membranes by :

Download or read book Current Topics in Membranes written by and published by Academic Press. This book was released on 1992-01-08 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Topics in Membranes

Latest Findings Of Omega-3 Long Chain Polyunsaturated Fatty Acids: From Molecular Mechanisms To New Applications In Health And Diseases

Download Latest Findings Of Omega-3 Long Chain Polyunsaturated Fatty Acids: From Molecular Mechanisms To New Applications In Health And Diseases PDF Online Free

Author : Maricela Rodriguez Cruz
Publisher : Bentham Science Publishers
ISBN 13 : 1608051773
Total Pages : 103 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis Latest Findings Of Omega-3 Long Chain Polyunsaturated Fatty Acids: From Molecular Mechanisms To New Applications In Health And Diseases by : Maricela Rodriguez Cruz

Download or read book Latest Findings Of Omega-3 Long Chain Polyunsaturated Fatty Acids: From Molecular Mechanisms To New Applications In Health And Diseases written by Maricela Rodriguez Cruz and published by Bentham Science Publishers. This book was released on 2011 with total page 103 pages. Available in PDF, EPUB and Kindle. Book excerpt: This E-book covers the main aspects about the benefits of omega-3 long chain polyunsaturated fatty acids (LC-PUFAs) to human health. The knowledge of physiological effects of LC-PUFAs at different levels is constantly expanding. Topics covered over 10 chapters thoroughly detail the role of omega-3 LCPUFAs in nutrition (gene regulation) and disease (clinical applications); information about food sources and recent intake recommendations is also explained. This book also discusses current data concerning the role of LC-PUFAs during pregnancy and lactation, in cognitive function, immune response.

Obesity, Fatty Liver and Liver Cancer

Author : Jun Yu
Publisher : Springer
ISBN 13 : 9811086842
Total Pages : 165 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Obesity, Fatty Liver and Liver Cancer by : Jun Yu

Download or read book Obesity, Fatty Liver and Liver Cancer written by Jun Yu and published by Springer. This book was released on 2018-06-28 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers a state-of-the-art illustration of recent discoveries concerning obesity-related fatty liver diseases and liver cancer. The contents are extensive and comprehensive. It brings important topics in the field all together under one umbrella, from epidemiology and etiology, molecular pathogenesis, cellular biology, epigenetics, immunology, microbiology, animal models to therapeutic approaches and treatments. All the book contributors are leading experts in the field. It will appeal to researchers, clinicians and graduate students in obesity, fatty liver diseases, GI/Liver cancer field. It may also yield benefits for pharmaceutical companies with regard to drug discovery.

Lipidomics in Health & Disease

Author : Xiangdong Wang
Publisher : Springer
ISBN 13 : 9811306206
Total Pages : 204 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Lipidomics in Health & Disease by : Xiangdong Wang

Download or read book Lipidomics in Health & Disease written by Xiangdong Wang and published by Springer. This book was released on 2018-08-30 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers the emerging area of science, Clinical Lipidomics, which is the application of lipidology to the understanding of physiological and pathophysiological changes of lipidomes, with a special focus on lipidomic profiles in human diseases. Lipidomics is widely used to map lipid molecular species in a biological system. Clinical lipidomic analysis has demonstrated the comprehensive characterization of molecular lipids in various severities, durations, and therapies as a critical tool in identification and validation of disease-specific biomarkers. This volume on Clinical Lipidomics will add to the literature and help advance the knowledge of the pathogenesis, diagnosis, prevention and treatment of diseases.

Neurodegeneration and Alzheimer's Disease

Author : Ralph N. Martins
Publisher : John Wiley & Sons
ISBN 13 : 1119356784
Total Pages : 548 pages
Book Rating : 4.1/5 (193 download)

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Book Synopsis Neurodegeneration and Alzheimer's Disease by : Ralph N. Martins

Download or read book Neurodegeneration and Alzheimer's Disease written by Ralph N. Martins and published by John Wiley & Sons. This book was released on 2019-07-10 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding the impact of diet, exercise, genetics, and hormones on the risk and development of Alzheimer’s and other neurogenerative diseases Diet is widely known to impact on neurological function. Nevertheless, academic texts discussing this relationship are relatively few in number. This book therefore fills an important gap in the current literature. Opening with an overview of neurodegenerative diseases, particularly Alzheimer’s disease, the text then focuses on explaining the means by which glycemic control and lipid metabolism – and associated nutritional and lifestyle variables – may factor into such disorders’ prevention and treatment. An international group of experts in the fields of food science and neurodegeneration have contributed chapters that examine Alzheimer’s disease within a broad range of contexts. Offering dietary, genetic, and hormonal perspectives, the authors explore topics ranging from sugar consumption to digestive fermentation, and Alzheimer’s disease animal models to the cognition-enhancing effects of physical exercise. Also included are overviews of the latest research into current and developing methods of treatment and diagnosis, as well as differential diagnostics. This groundbreaking book: Explores how glucose metabolism, insulin resistance, lipid metabolism, and high intake of refined carbohydrates are linked to Alzheimer's disease Discusses how genetic makeup can impact risk of Alzheimer’s and Parkinson’s disease Examines cognitive changes in neurodegeneration, lists current tests for determining cognitive impairment, and provides information concerning differential diagnosis Discusses potential advantages of increasing antioxidant and micronutrient intake Reviews hormonal influences on neurodegeneration Examines the links between protein intake and Alzheimer’s disease. Neurodegeneration and Alzheimer's Disease is an essential resource for researchers, medical practitioners, dietitians, and students with an interest in neurological diseases and their diagnosis and risk factors, as well as diet-related conditions such as diabetes and obesity. Lifestyle and diet influence neurodegeneration risk, and a better understanding of this evidence amongst health professionals will hopefully lead to greater public awareness of how to reduce the likelihood of these widespread conditions.

Polyploidy and Genome Evolution

Author : Pamela Soltis
Publisher : Springer Science & Business Media
ISBN 13 : 3642314414
Total Pages : 416 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Polyploidy and Genome Evolution by : Pamela Soltis

Download or read book Polyploidy and Genome Evolution written by Pamela Soltis and published by Springer Science & Business Media. This book was released on 2012-10-03 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polyploidy – whole-genome duplication (WGD) – is a fundamental driver of biodiversity with significant consequences for genome structure, organization, and evolution. Once considered a speciation process common only in plants, polyploidy is now recognized to have played a major role in the structure, gene content, and evolution of most eukaryotic genomes. In fact, the diversity of eukaryotes seems closely tied to multiple WGDs. Polyploidy generates new genomic interactions – initially resulting in “genomic and transcriptomic shock” – that must be resolved in a new polyploid lineage. This process essentially acts as a “reset” button, resulting in genomic changes that may ultimately promote adaptive speciation. This book brings together for the first time the conceptual and theoretical underpinnings of polyploid genome evolution with syntheses of the patterns and processes of genome evolution in diverse polyploid groups. Because polyploidy is most common and best studied in plants, the book emphasizes plant models, but recent studies of vertebrates and fungi are providing fresh perspectives on factors that allow polyploid speciation and shape polyploid genomes. The emerging paradigm is that polyploidy – through alterations in genome structure and gene regulation – generates genetic and phenotypic novelty that manifests itself at the chromosomal, physiological, and organismal levels, with long-term ecological and evolutionary consequences.