Fate And Effects Of Anticancer Drugs In The Environment

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Fate and Effects of Anticancer Drugs in the Environment

Author : Ester Heath
Publisher : Springer Nature
ISBN 13 : 3030210480
Total Pages : 472 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Fate and Effects of Anticancer Drugs in the Environment by : Ester Heath

Download or read book Fate and Effects of Anticancer Drugs in the Environment written by Ester Heath and published by Springer Nature. This book was released on 2020-01-01 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides current knowledge and research on the presence and effects of anticancer drug residues in the aqueous environment and covers all relevant aspects of the presence of these residues in wastewaters and natural aquatic systems, where numerous analogies between their pharmacokinetics and pharmacodynamics in humans and their effects in the environment can be drawn. This book comprises of 18 chapters and represents the combined work of leading scientists from different research institutions from across the globe. We present the state of the art in the field of anticancer drug residues in the aquatic environment while being cognizant of the many challenges that remain.

Fate and Effects of the Residues of Anticancer Drugs in the Environment

Author : Ester Heath
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (958 download)

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Book Synopsis Fate and Effects of the Residues of Anticancer Drugs in the Environment by : Ester Heath

Download or read book Fate and Effects of the Residues of Anticancer Drugs in the Environment written by Ester Heath and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Environmental Fate of Selected Anticancer Drugs

Author :
Publisher :
ISBN 13 :
Total Pages : 180 pages
Book Rating : 4.:/5 (932 download)

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Book Synopsis Environmental Fate of Selected Anticancer Drugs by :

Download or read book Environmental Fate of Selected Anticancer Drugs written by and published by . This book was released on 2015 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Emerging Contaminants in the Environment

Author : Hemen Sarma
Publisher : Elsevier
ISBN 13 : 032385981X
Total Pages : 713 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Emerging Contaminants in the Environment by : Hemen Sarma

Download or read book Emerging Contaminants in the Environment written by Hemen Sarma and published by Elsevier. This book was released on 2022-01-08 with total page 713 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emerging Contaminants in the Environment: Challenges and Sustainable Practices covers all aspects of emerging contaminants in the environment, from basic understanding to different types of emerging contaminants and how these threaten organisms, their environmental fate studies, detection methods, and sustainable practices of dealing with contaminants. Emerging contaminant remediation is a pressing need due to the ever-increasing pollution in the environment, and it has gained a lot of scientific and public attention due to its high effectiveness and sustainability. The discussions in the book on the bioremediation of these contaminants are covered from the perspective of proven technologies and practices through case studies and real-world data. One of the main benefits of this book is that it summarizes future challenges and sustainable solutions. It can, therefore, become an effective guide to the elimination (through sustainable practices) of emerging contaminants. At the back of these explorations on sustainable bioremediation of emerging contaminants lies the set of 17 goals articulated by the United Nations in its 2030 Agenda for Sustainable Development, adopted by all its member states. This book provides academics, researchers, students, and practitioners interested in the detection and elimination of emerging contaminants from the environment, with the latest advances by leading experts in emerging contaminants the field of environmental sciences. Covers most aspects of the most predominant emerging contaminants in the environment, including in soil, air, and water Describes the occurrence of these contaminants, the problems they cause, and the sustainable practices to deal with the contaminants Includes data from case studies to provide real-world examples of sustainable practices and emerging contaminant remediation

Pharmaceutical Residues in Freshwater: Hazards and Policy Responses

Author : Organisation for Economic Co-Operation and Development (OECD)
Publisher : IWA Publishing
ISBN 13 : 1789061814
Total Pages : 138 pages
Book Rating : 4.7/5 (89 download)

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Book Synopsis Pharmaceutical Residues in Freshwater: Hazards and Policy Responses by : Organisation for Economic Co-Operation and Development (OECD)

Download or read book Pharmaceutical Residues in Freshwater: Hazards and Policy Responses written by Organisation for Economic Co-Operation and Development (OECD) and published by IWA Publishing. This book was released on 2020-07-15 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report calls for a better understanding of the effects of pharmaceutical residues in the environment, greater international collaboration and accountability distribution, and policy actions to prevent and remedy emerging concerns. Laboratory and field tests show traces of oral contraceptives causing the feminisation of fish and amphibians, and residues of psychiatric drugs altering fish behaviour. Antimicrobial resistance, linked to the overuse of antibiotics, has rapidly escalated into a global health crisis. Unless adequate measures are taken to manage the risks, pharmaceutical residues will increasingly be released into the environment as ageing populations, advances in healthcare, and intensification of meat and fish production spur the demand for pharmaceuticals worldwide. The report outlines a collective, life‑cycle approach to managing pharmaceuticals in the environment. A policy mix of source‑directed, use‑orientated and end‑of‑pipe measures, involving several policy sectors, can help to improve health and protect the environment.

Hospital Wastewaters

Author : Paola Verlicchi
Publisher : Springer
ISBN 13 : 3319621785
Total Pages : 243 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Hospital Wastewaters by : Paola Verlicchi

Download or read book Hospital Wastewaters written by Paola Verlicchi and published by Springer. This book was released on 2017-09-04 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume addresses hospital effluents in terms of their composition and the management and treatment strategies currently (being) adopted around the globe. In this context, one major focus is on pharmaceutical compounds: their observed concentration range, ecotoxicological effects, and the removal efficiency achieved by the different technologies. Another focus is on management strategies (dedicated hospital wastewater treatment, or a combined approach also involving urban wastewater) and currently adopted treatments to reduce the released pollutant load. Innovative and promising technologies under investigation at the lab and pilot scale are presented. A discussion of remaining knowledge gaps and future research requirements rounds out the coverage. The respective chapters, written by experts in the different fields, provide useful information for a broad audience: scientists involved in the management and treatment of hospital effluents and wastewater containing micropollutants, administrators and decision-makers, legislators involved in the authorization and management of healthcare structure effluents, and environmental engineers involved in the design of wastewater treatment plants, as well as newcomers and students interested in these issues.

Medicinal Chemistry of Anticancer Drugs

Author : Carmen Avendaño
Publisher : Elsevier
ISBN 13 : 0444626670
Total Pages : 767 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Medicinal Chemistry of Anticancer Drugs by : Carmen Avendaño

Download or read book Medicinal Chemistry of Anticancer Drugs written by Carmen Avendaño and published by Elsevier. This book was released on 2015-06-11 with total page 767 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells, and resistance to antitumor drugs continues to be investigated. While these therapies are in their infancy, they hold promise of more effective therapies with fewer side effects. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a sorely needed update from the point of view of medicinal chemistry and drug design. Presents information in a clear and concise way using a large number of figures Historical background provides insights on how the process of drug discovery in the anticancer field has evolved Extensive references to primary literature

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 427: Skin Absorption: In Vivo Method

Author : OECD
Publisher : OECD Publishing
ISBN 13 : 9264071067
Total Pages : 8 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 427: Skin Absorption: In Vivo Method by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 427: Skin Absorption: In Vivo Method written by OECD and published by OECD Publishing. This book was released on 2004-11-23 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt: The in vivo percutaneous absorption study set out in this Test Guideline provides the linkage necessary to extrapolate from oral studies when making safety assessments following dermal exposure. The in vivo method, described in this guideline ...

Handbook of Anticancer Drugs from Marine Origin

Author : Se-Kwon Kim
Publisher : Springer
ISBN 13 : 3319071459
Total Pages : 801 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Handbook of Anticancer Drugs from Marine Origin by : Se-Kwon Kim

Download or read book Handbook of Anticancer Drugs from Marine Origin written by Se-Kwon Kim and published by Springer. This book was released on 2014-11-27 with total page 801 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely desk reference focuses on marine-derived bioactive substances which have biological, medical and industrial applications. The medicinal value of these marine natural products are assessed and discussed. Their function as a new and important resource in novel, anticancer drug discovery research is also presented in international contributions from several research groups. For example, the potential role of Spongistatin, Apratoxin A, Eribulin mesylate, phlorotannins, fucoidan, as anticancer agents is explained. The mechanism of action of bioactive compounds present in marine algae, bacteria, fungus, sponges, seaweeds and other marine animals and plants are illustrated via several mechanisms. In addition, this handbook lists various compounds that are active candidates in chemoprevention and their target actions. The handbook also places into context the demand for anticancer nutraceuticals and their use as potential anti-cancer pharmaceuticals and medicines. This study of advanced and future types of natural compounds from marine sources is written to facilitate the understanding of Biotechnology and its application to marine natural product drug discovery research.

How Tobacco Smoke Causes Disease

Author : United States. Public Health Service. Office of the Surgeon General
Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis How Tobacco Smoke Causes Disease by : United States. Public Health Service. Office of the Surgeon General

Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Environmental Micropollutants

Author : Muhammad Zaffar Hashmi
Publisher : Elsevier
ISBN 13 : 0323906753
Total Pages : 488 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Environmental Micropollutants by : Muhammad Zaffar Hashmi

Download or read book Environmental Micropollutants written by Muhammad Zaffar Hashmi and published by Elsevier. This book was released on 2022-04-08 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental Micropollutants, the latest volume in the Advances in Environmental Pollution Research series, presents the latest research on various environmental micropollutants, as well as their impacts on health and the economy, also addressing the best possible solutions to address the risks presented by these pollutants. The book covers solutions for dusts, infectious particles, heavy metals, organophosphates, atmospheric toxic organic micropollutants, fungal spores, pollutants from E-waste, and antibiotics threats, providing researchers working in environmental science and management with key knowledge to address this increasingly important concern. These types of micropollutants can be present in water, air and soil and can harm health even in low quantities, hence this book covers the challenges these pollutants pose to the environment and human health, presenting practical solutions. Identifies key micropollutants in the environment and examines their impacts on human health and the economy Presents methods and treatment technologies for addressing the problem of micropollutants Offers the latest research on a variety of micropollutants and the best solutions for each

Drug-like Properties: Concepts, Structure Design and Methods

Author : Li Di
Publisher : Elsevier
ISBN 13 : 0080557619
Total Pages : 549 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Drug-like Properties: Concepts, Structure Design and Methods by : Li Di

Download or read book Drug-like Properties: Concepts, Structure Design and Methods written by Li Di and published by Elsevier. This book was released on 2010-07-26 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product. Understanding ADME/Tox is critical for all drug researchers, owing to its increasing importance in advancing high quality candidates to clinical studies and the processes of drug discovery. If the properties are weak, the candidate will have a high risk of failure or be less desirable as a drug product. This book is a tool and resource for scientists engaged in, or preparing for, the selection and optimization process. The authors describe how properties affect in vivo pharmacological activity and impact in vitro assays. Individual drug-like properties are discussed from a practical point of view, such as solubility, permeability and metabolic stability, with regard to fundamental understanding, applications of property data in drug discovery and examples of structural modifications that have achieved improved property performance. The authors also review various methods for the screening (high throughput), diagnosis (medium throughput) and in-depth (low throughput) analysis of drug properties. Serves as an essential working handbook aimed at scientists and students in medicinal chemistry Provides practical, step-by-step guidance on property fundamentals, effects, structure-property relationships, and structure modification strategies Discusses improvements in pharmacokinetics from a practical chemist's standpoint

Medicinal Chemistry of Chemotherapeutic Agents

Author : Pratap Chandra Acharya
Publisher : Academic Press
ISBN 13 : 0323907016
Total Pages : 688 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Medicinal Chemistry of Chemotherapeutic Agents by : Pratap Chandra Acharya

Download or read book Medicinal Chemistry of Chemotherapeutic Agents written by Pratap Chandra Acharya and published by Academic Press. This book was released on 2023-03-09 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal Chemistry of Chemotherapeutic Agents: A Comprehensive Resource of Anti-infective and Anti-cancer Drugs focuses on the basics and fundamentals of chemistry involved in chemotherapeutic agents. Each chapter comprises distinct chemical classifications that include structure and IUPAC nomenclature, synthetic schemes and routes for each drug, mechanism of the drug action, metabolic pathway and structure–activity relationship (SAR) studies. The book covers current research focused on drug resistance and methods to overcome it, the development of newer drugs belonging to each category of the chemotherapeutic agents, molecules currently under clinical trials, and newly approved drugs, if any. This book will be a valuable resource for academics and researchers, helping them to understand the fundamentals of the medicinal chemistry of the chemotherapeutic agents. Includes current research focused on drug resistance and methods to overcome problems Outlines synthetic schemes and metabolic pathways of chemotherapeutic agents Discusses molecules under clinical trials and newly approved drugs

Emerging Anti-Aging Strategies

Author : Syed Ibrahim Rizvi
Publisher : Springer Nature
ISBN 13 : 9811974438
Total Pages : 345 pages
Book Rating : 4.8/5 (119 download)

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Book Synopsis Emerging Anti-Aging Strategies by : Syed Ibrahim Rizvi

Download or read book Emerging Anti-Aging Strategies written by Syed Ibrahim Rizvi and published by Springer Nature. This book was released on 2023-01-30 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book focuses on the emerging anti-aging approaches for maintaining better health in old age. It provides a current understanding of the underlying principle, possible targets, implementation approaches, and efficacy of the various anti-aging strategies. The chapters include a wide range of topics incorporating the major advances in anti-aging strategies, including telomerase activation, stem cell therapy, autophagy induction, sirtuin activation, and dietary restrictions. Further, it discusses the epigenetic mechanisms underlying aging-related processes and epigenetic strategies to delay and reverse aging-related diseases. The book covers the strategy based on tissue engineering and regenerative medicine for understanding the complexity of aging and restoring the functionalities of organ systems. It further presents the applications of melatonin supplementation-based anti-aging therapeutic intervention. Finally, the book reviews the ethical dimension of anti-aging intervention strategies. This book is immensely useful to scientists and researchers from various disciplines in the life sciences.

The ELSI Handbook of Nanotechnology

Author : Chaudhery Mustansar Hussain
Publisher : John Wiley & Sons
ISBN 13 : 1119592968
Total Pages : 580 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis The ELSI Handbook of Nanotechnology by : Chaudhery Mustansar Hussain

Download or read book The ELSI Handbook of Nanotechnology written by Chaudhery Mustansar Hussain and published by John Wiley & Sons. This book was released on 2020-03-31 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Handbook focuses on the recent advancements in Safety, Risk, Ethical Society and Legal Implications (ESLI) as well as its commercialization of nanotechnology, such as manufacturing. Nano is moving out of its relaxation phase of scientific route, and as new products go to market, organizations all over the world, as well as the general public, are discussing the environmental and health issues associated with nanotechnology. Nongovernmental science organizations have long since reacted; however, now the social sciences have begun to study the cultural portent of nanotechnology. Societal concerns and their newly constructed concepts, show nanoscience interconnected with the economy, ecology, health, and governance. This handbook addresses these new challenges and is divided into 7 sections: Nanomaterials and the Environment; Life Cycle Environmental Implications of Nanomanufacturing; Bioavailability and Toxicity of Manufactured Nanoparticles in Terrestrial Environments; Occupational Health Hazards of Nanoparticles; Ethical Issues in Nanotechnology; Commercialization of Nanotechnology; Legalization of Nanotechnology.

Emerging Contaminants in the Terrestrial-Aquatic-Atmosphere Continuum

Author : Willis Gwenzi
Publisher : Elsevier
ISBN 13 : 0323903444
Total Pages : 432 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Emerging Contaminants in the Terrestrial-Aquatic-Atmosphere Continuum by : Willis Gwenzi

Download or read book Emerging Contaminants in the Terrestrial-Aquatic-Atmosphere Continuum written by Willis Gwenzi and published by Elsevier. This book was released on 2022-05-06 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emerging Contaminants in Terrestrial and Aquatic Environments: Occurrence, Health Risks, and Mitigation provides the latest information on the synthesis of the occurrence, behavior, human health risks and mitigation of emerging contaminants in developing countries. First highlighting sources, industrial applications, key drivers and regulatory frameworks, the book then goes on to discuss the nature of emerging contaminants, including organic (e.g., pharmaceuticals), inorganic (e.g., rare earth elements) and biological agents (e.g., antimicrobial resistance). It then presents the dissemination, environmental behavior, and fate in terrestrial and aquatic systems as well as the human and ecological exposure pathways, health risks, and more. Offering a transdisciplinary approach that brings together perspectives and contributions from experts in environmental sciences, hydrology, environmental engineering, ecotoxicology, chemistry, material sciences, and legal and policy aspects, the book provides an approachable and flexible resource for researchers and upper-level students with diverse academic backgrounds. Adopts a lifecycle perspective by including industrial applications, behavior and fate and human health risks and removal Focuses on developing regions and covers a wide range of emerging contaminants, including those often overlooked in earlier books such as rare earth elements and antimicrobial resistance Presents a clear understanding of the contrasts between developed and developing countries with respect to emerging contaminants and their health risks and mitigation, including water and wastewater treatment systems commonly used in developing countries Covers human and ecological health risks in developing countries

Management of Contaminants of Emerging Concern (CEC) in Environment

Author : Pardeep Singh
Publisher : Elsevier
ISBN 13 : 0128222646
Total Pages : 468 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Management of Contaminants of Emerging Concern (CEC) in Environment by : Pardeep Singh

Download or read book Management of Contaminants of Emerging Concern (CEC) in Environment written by Pardeep Singh and published by Elsevier. This book was released on 2021-03-12 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: Management of Contaminants of Emerging Concern (CEC) in Environment provides information about new concepts and latest developments in origin, reaction pathways, transportation, transformation products, identification, and adverse effects of CEC, as well as recent remediation technologies and tools for CEC. The book explores processes such as nanotechnology for the degradation of CEC by using various heterogeneous catalysts. The chapters incorporate both theoretical and practical aspects and can serve as a baseline for future studies. So, Management of Contaminants of Emerging Concern (CEC) in Environment is an indispensable resource for university students, teachers, and researchers, especially those working in the area of remediation and management of contaminants of emerging concern. Takes a holistic approach, focusing on the origin of contaminants, type of contaminants, remediation technologies, regulations and legal aspects Applies chemical, physical and biological processes for the treatment of emerging contaminants Written by a team of internationally reputed and rising researchers