Fast Facts For Patients Chronic Lymphocytic Leukemia

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Fast Facts: Chronic Lymphocytic Leukemia

Author : Toby A. Eyre
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318071609
Total Pages : 80 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Fast Facts: Chronic Lymphocytic Leukemia by : Toby A. Eyre

Download or read book Fast Facts: Chronic Lymphocytic Leukemia written by Toby A. Eyre and published by Karger Medical and Scientific Publishers. This book was released on 2023-05-23 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic lymphocytic leukemia (CLL) is the most diagnosed leukemia in the Western world, accounting for approximately 25% of all new leukemia diagnoses. In recent years, remarkable progress has been made in our understanding of both the pathophysiology and genetics of CLL. While the disease generally affects older adults and initially follows an indolent course, cytogenetic and molecular profiling have helped to predict clinical outcomes. Greater prognostication, alongside the development of an increasing armamentarium of novel targeted therapies, has enabled us to provide more personalized management options for patients. Table of Contents • Epidemiology and etiology • Molecular biology and genetics • Diagnosis, staging and prognosis • Management • Research directions

Fast Facts: Chronic Lymphocytic Leukemia

Author : T.A. Eyre
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318069744
Total Pages : 74 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Fast Facts: Chronic Lymphocytic Leukemia by : T.A. Eyre

Download or read book Fast Facts: Chronic Lymphocytic Leukemia written by T.A. Eyre and published by Karger Medical and Scientific Publishers. This book was released on 2022-02-11 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic lymphocytic leukemia (CLL) is the most diagnosed leukemia in the Western world, accounting for approximately 25% of all new leukemia diagnoses. In recent years, remarkable progress has been made in our understanding of both the pathophysiology and genetics of CLL. While the disease generally affects older adults and initially follows an indolent course, cytogenetic and molecular profiling have helped to predict clinical outcomes. Greater prognostication, alongside the development of an increasing armamentarium of novel targeted therapies, has enabled us to provide more personalized management options for patients. 'Fast Facts: Chronic Lymphocytic Leukemia' covers the epidemiology, etiology, diagnosis and staging of the disease, and the molecular and genetic aspects that underpin treatment and prognosis. It provides a concise overview of treatment options, in both the front-line and relapsed/refractory settings, with particular focus on the novel targeted agents that have overcome many adverse prognostic factors, improving overall survival. Table of Contents: • Epidemiology and etiology • Molecular biology and genetics • Diagnosis, staging and prognosis • Management • Research directions

Fast Facts: Leukemia

Author : J. Loke
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318069493
Total Pages : 138 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Fast Facts: Leukemia by : J. Loke

Download or read book Fast Facts: Leukemia written by J. Loke and published by Karger Medical and Scientific Publishers. This book was released on 2022-03-02 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leukemia is a hematologic malignancy arising from hematopoietic stem cells (HSCs) in the bone marrow. Starting with a detailed description of hematopoiesis and what goes wrong in leukemia, this concise guide covers all aspects of the four most common subtypes of the disease. Although the incidence and prevalence of leukemia are rising worldwide, survival rates are also increasing. However, both the effects of the disease and the adverse effects of treatment remain complex challenges. Yet, as our understanding of the molecular landscape increases, therapeutic options are becoming more personalized. This revised and updated second edition of 'Fast Facts: Leukemia' addresses the causes and risk factors for each subtype of leukemia, the initial and confirmatory diagnostic tests, and the latest treatment options. Designed as a comprehensive primer for physician assistants, nurse practitioners, primary care providers, oncology nurses, hematology/ oncology trainees and pharmacists, this resource will help the non-specialist and those in training to identify leukemia early and provide a thorough understanding of the pathology and genetic basis of the disease, treatment options, and effective approaches to emergency and supportive care. Table of Contents: • Understanding blood and its components • What is leukemia? • Epidemiology, etiology and risk factors • Diagnosis • Staging and general management • Supportive care • Emergencies in leukemia

Fast Facts: Treatment-Free Remission in Chronic Myeloid Leukemia

Author : S. Potluri
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318068349
Total Pages : 54 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Fast Facts: Treatment-Free Remission in Chronic Myeloid Leukemia by : S. Potluri

Download or read book Fast Facts: Treatment-Free Remission in Chronic Myeloid Leukemia written by S. Potluri and published by Karger Medical and Scientific Publishers. This book was released on 2021-01-26 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt: The tyrosine kinase inhibitor (TKI) imatinib was the first treatment to specifically target cancer cells, rather than the relatively indiscriminate effects of conventional chemotherapy on any rapidly dividing cells. This concept of targeted treatment in cancer is one of the important advances in modern medicine in the last 30 years. Indeed, treatment with TKIs has transformed chronic myeloid leukemia (CML) from a cancer with a poor prognosis to one in which many patients can expect a normal lifespan. Success with the TKIs has prompted the question of whether it is desirable – or feasible – for patients to remain on treatment for long periods. While the TKIs are targeted, they are associated with considerable toxicity, and long-term treatment has important economic implications for health services and patients. Thus, the concept of treatment-free remission (TFR) has emerged for patients in deep clinical remission. Clinical research over the last decade has focused on whether treatment can be stopped, how to best monitor patients while off treatment, and how to intervene before a clinical relapse. As this research progresses, the tantalizing prospect of a cure for some patients seems increasingly feasible. This new Fast Facts title outlines this trail-blazing approach to the long-term management of patients living with CML in remission. It explains the concepts of molecular and hematologic relapse, the highly sensitive technologies that allow disease monitoring, and how TFR is best managed in practice. It is a concise educational resource, ideal for any healthcare professional involved in the treatment of patients with CML who wants to understand TFR, particularly clinical nurse specialists and pharmacists who increasingly help clinicians to run CML clinics. Table of Contents: • The concept of treatment-free remission • Measurement of disease burden • Clinical practice • Future directions

Fast Facts: Leucemia

Author : J. Loke
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318066338
Total Pages : 140 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Fast Facts: Leucemia by : J. Loke

Download or read book Fast Facts: Leucemia written by J. Loke and published by Karger Medical and Scientific Publishers. This book was released on 2019-11-28 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aunque la incidencia y prevalencia de leucemia está aumentando a nivel mundial, los avances en el diagnóstico y el tratamiento indican que las tasas de supervivencia también están aumentando. Comenzando con una descripción detallada de la hematopoyesis y lo que está mal en caso de la leucemia, esta guía concisa abarca todos los aspectos de los cuatro subtipos más frecuentes de la enfermedad: leucemia mieloide aguda (AML), leucemia linfoblástica aguda (ALL), leucemia mieloide crónica (CML) y leucemia linfocítica crónica (CLL). Este libro considera las causas y factores de riesgo para cada subtipo de leucemia, las pruebas diagnósticas iniciales y confirmatorias (incluyendo métodos de citogenética y genética molecular) y las opciones de tratamiento más recientes. Tanto los efectos de la enfermedad como los efectos adversos del tratamiento siguen representando un desafío complejo y se considera el abordaje multidisciplinario necesario para una atención de apoyo efectiva. Por último, se examinan las complicaciones urgentes que requieren atención de emergencia. Diseñado como una guía integral para enfermeras especializadas, médicos de atención primaria y residentes de hematología/oncología, este recurso ayudará a quienes no son especialistas a identificar la leucemia en etapas tempranas y proporciona una comprensión detallada de la patología y la base genética de la enfermedad, las opciones de tratamiento y los abordajes efectivos a la atención de urgencia y cuidados de apoyo.

Ferri's Practical Guide: Fast Facts for Patient Care E-Book

Author : Fred F. Ferri
Publisher : Elsevier Health Sciences
ISBN 13 : 1455744581
Total Pages : 457 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Ferri's Practical Guide: Fast Facts for Patient Care E-Book by : Fred F. Ferri

Download or read book Ferri's Practical Guide: Fast Facts for Patient Care E-Book written by Fred F. Ferri and published by Elsevier Health Sciences. This book was released on 2014-03-28 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: For nearly 25 years, Ferri's concise, pocket-sized resource has served as the go-to reference for practical, clinical information among students, residents, and other medical professionals. Formerly known as Practical Guide to the Care of the Medical Patient, this volume continues to provide a fast, effective, and efficient way to identify the important clinical, laboratory, and diagnostic imaging information you need to get through your internal medicine clerkship or residency. - Consult this title on your favorite device, conduct rapid searches, and adjust font sizes for optimal readability. - Benefit from the expert guidance of Dr. Fred Ferri, a leading teacher, clinician, and author. - Confidently manage patients with the latest clinical information, drug therapies, and lab tests. - Apply the latest knowledge and techniques with this updated and streamlined title, which still stays true to the Ferri name. - Quickly find important information with content organized into three major sections: Section I, titled "Surviving the Wards," contains information on charting, laboratory evaluation and formulary; Section II provides the differential diagnosis of common signs and symptoms likely to be encountered in the acute care setting; Section III has been completely revised and subdivided into 11 specialty specific diseases and disorders. - Carry just the sections you need, add personalized materials, and keep everything together and safe with an improved ring binder and design. - Access the full text and procedural videos online at Expert Consult.

Fast Facts: Leukemia

Author : Justin Loke
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318069965
Total Pages : 138 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Fast Facts: Leukemia by : Justin Loke

Download or read book Fast Facts: Leukemia written by Justin Loke and published by Karger Medical and Scientific Publishers. This book was released on 2022-02-22 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leukemia is a hematologic malignancy arising from hematopoietic stem cells (HSCs) in the bone marrow. Starting with a detailed description of hematopoiesis and what goes wrong in leukemia, this concise guide covers all aspects of the four most common subtypes of the disease. Although the incidence and prevalence of leukemia are rising worldwide, survival rates are also increasing. However, both the effects of the disease and the adverse effects of treatment remain complex challenges. Yet, as our understanding of the molecular landscape increases, therapeutic options are becoming more personalized. This revised and updated second edition of 'Fast Facts: Leukemia' addresses the causes and risk factors for each subtype of leukemia, the initial and confirmatory diagnostic tests, and the latest treatment options. Designed as a comprehensive primer for physician assistants, nurse practitioners, primary care providers, oncology nurses, hematology/ oncology trainees and pharmacists, this resource will help the non-specialist and those in training to identify leukemia early and provide a thorough understanding of the pathology and genetic basis of the disease, treatment options, and effective approaches to emergency and supportive care. Table of Contents: • Understanding blood and its components • What is leukemia? • Epidemiology, etiology and risk factors • Diagnosis • Staging and general management • Supportive care • Emergencies in leukemia

Fast Facts: Lymphoma

Author : Grapham P. Collins
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318072990
Total Pages : 188 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Fast Facts: Lymphoma by : Grapham P. Collins

Download or read book Fast Facts: Lymphoma written by Grapham P. Collins and published by Karger Medical and Scientific Publishers. This book was released on 2023-08-09 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lymphoma can be broadly defined as a cancer of mature lymphocytes. Our understanding of the biology of normal lymphocytes and lymphoma has grown at a tremendous pace, and this is now directly translating into changes in clinical practice. This became evident with the introduction of one of the first therapeutic monoclonal antibodies into cancer medicine, the CD20-directed antibody rituximab, which has led to significant benefit for patients with B-cell lymphomas. Since then, a raft of novel agents has entered clinical practice, including targeted small molecules, antibody-drug conjugates, bispecific antibodies, and chimeric antigen receptor (CAR) T cells. This new edition of 'Fast Facts: Lymphoma' has been updated to include recent changes in our understanding of lymphoma biology as well as improvements in diagnostics and therapeutics.

Fast Facts: Systemic Mastocytosis

Author : Deepti H. Radia
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318071617
Total Pages : 105 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Fast Facts: Systemic Mastocytosis by : Deepti H. Radia

Download or read book Fast Facts: Systemic Mastocytosis written by Deepti H. Radia and published by Karger Medical and Scientific Publishers. This book was released on 2023-04-04 with total page 105 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Fast Facts: Skin Cancer

Author : Karen L. Agnew
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 1908541393
Total Pages : 118 pages
Book Rating : 4.9/5 (85 download)

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Book Synopsis Fast Facts: Skin Cancer by : Karen L. Agnew

Download or read book Fast Facts: Skin Cancer written by Karen L. Agnew and published by Karger Medical and Scientific Publishers. This book was released on 2015-09-16 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: Skin cancer is both preventable and treatable, yet it is becoming alarmingly common. The key to successful treatment (other than education and prevention) is early recognition and swift referral. 'Fast Facts: Skin Cancer' has been written by three international experts to equip healthcare professionals with the necessary skills to save lives. Highlights include: • Expert presentation of the basic facts on epidemiology, causation, presentation and management • Over 100 color illustrations to assist with the identification of at-risk individuals and early lesions • Pull-out tables of cancer staging for cutaneous squamous cell carcinoma and melanoma • Advice to give patients on self-examination • A thorough overview of all treatment options: topical therapies, cryotherapy, curettage and electrosurgery, photodynamic therapy and lasers, radiotherapy, surgical excision and Mohs micrographic surgery • Discussion of preventive measures This fully updated second edition is a practical evidence-based resource, written from an international perspective to reflect national and international guidelines. It will assist clinical practice, education, training, audit and research, and is essential reading for generalists and specialists alike. Contents: • Epidemiology • Pathogenesis • Clinical features and diagnosis • Management • Prognosis • Prevention; Future trends

Fast Facts: Medical Statistics

Author : Richard Kay
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 1912776677
Total Pages : 110 pages
Book Rating : 4.9/5 (127 download)

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Book Synopsis Fast Facts: Medical Statistics by : Richard Kay

Download or read book Fast Facts: Medical Statistics written by Richard Kay and published by Karger Medical and Scientific Publishers. This book was released on 2020-07-17 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using real examples from oncology trials, but keeping it simple, this concise resource explains the basic principles of medical statistics so that you can better appraise clinical trial results. Key concepts covered in this book include: • hypothesis testing • Kaplan–Meier curves and other graphic representations of data • calculating the power of a study • the stopping rules for efficacy and futility. ' Fast Facts: Medical Statistics' is aimed at all clinicians, clinical scientists, medical writers and regulatory personnel who need a better understanding of the statistical terms and methods used in the planning of studies and the analysis of clinical trial data. If you have ever wanted to know what a type I error is, how an odds ratio is calculated or what a forest plot is really all about, then this is the book for you. Contents: • Statistical inference • Analysis of time-to-event endpoints • Power and sample size • Multiplicity • Interim analysis • Modeling • Graphical methods

Fast Facts: Acute Lymphoblastic Leukemia

Author : Bela Wrench
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318069779
Total Pages : 108 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Fast Facts: Acute Lymphoblastic Leukemia by : Bela Wrench

Download or read book Fast Facts: Acute Lymphoblastic Leukemia written by Bela Wrench and published by Karger Medical and Scientific Publishers. This book was released on 2022-06-30 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute lymphoblastic leukemia (ALL) is the most diagnosed childhood cancer worldwide. Although rare in adults, this aggressive cancer also shows a second smaller incidence peak in later middle age.

Modern genetic profiling techniques are providing a better understanding of the molecular biology of ALL, which, in turn, is leading to significant advances in diagnosis, prognostication and therapy selection. Ongoing refinement of risk-adapted frontline treatment protocols, use of novel targeted therapies and better supportive care are improving outcomes for patients with ALL.

Fast Facts: Acute Lymphoblastic Leukemia covers the epidemiology, etiology, diagnosis and classification of ALL as well as the measurement of minimal residual disease to determine prognosis. It provides guidance on frontline therapies and the treatment of relapsed and refractory ALL, including the use of newer targeted agents and the role of allogeneic stem-cell transplantation. Looking to the future, it also considers the approaches and refinements that are in development for ALL. Table of Contents:

Epidemiology, pathophysiology and etiology

Diagnosis

Prognostic factors

Treatment

Relapsed or refractory ALL

Future directions

Fast Facts: Marginal Zone Lymphoma

Author : Shirly D'Sa
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318073229
Total Pages : 135 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Fast Facts: Marginal Zone Lymphoma by : Shirly D'Sa

Download or read book Fast Facts: Marginal Zone Lymphoma written by Shirly D'Sa and published by Karger Medical and Scientific Publishers. This book was released on 2024-08-13 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Fast Facts: Marginal Zone Lymphoma' provides an overview of MZL for healthcare professionals and others with an interest in this blood cancer. It summarizes what is known about the pathophysiology of the disease, and discusses the importance of accurate diagnosis, staging, and prognosis, together with existing approaches to treatment and monitoring, including the latest evidence for new therapies in the R/R setting. With an eye to the future, it also reviews some of the therapies in development, which may ultimately improve quality of life and ensure better outcomes for patients with MZL.

Childhood Acute Lymphoblastic Leukemia

Author : Ajay Vora
Publisher : Springer
ISBN 13 : 3319397087
Total Pages : 345 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Childhood Acute Lymphoblastic Leukemia by : Ajay Vora

Download or read book Childhood Acute Lymphoblastic Leukemia written by Ajay Vora and published by Springer. This book was released on 2017-04-21 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.

Fast Facts: Measurable Residual Disease

Author : Justin Loke
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318068241
Total Pages : 33 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Fast Facts: Measurable Residual Disease by : Justin Loke

Download or read book Fast Facts: Measurable Residual Disease written by Justin Loke and published by Karger Medical and Scientific Publishers. This book was released on 2021-01-26 with total page 33 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conventional methods of detecting disease remission in cancers such as leukemia rely on microscopic analysis of tissue samples. Measurable (or minimal) residual disease (MRD) describes the presence of disease beyond the levels of sensitivity afforded by microscopy. Fast Facts: Measurable Residual Disease describes what is meant by MRD, the opportunities and challenges afforded by its identification and the advantages and disadvantages of the methods used for its detection. Specific examples are given to illustrate the implications of detecting MRD in different disease scenarios, with emphasis on acute myeloid and lymphoblastic leukemias. With the recognition and monitoring of MRD likely to play an increasingly important role in disease prognosis and subsequent treatment direction, this accessible resource is ideal for any healthcare professional wanting to know more about this exciting and fast-moving area. Table of Contents: • What is measurable residual disease? • How is MRD measured? • What is the significance of MRD?

Fast Facts: Follicular Lymphoma

Author : Pamela McKay
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318073202
Total Pages : 116 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Fast Facts: Follicular Lymphoma by : Pamela McKay

Download or read book Fast Facts: Follicular Lymphoma written by Pamela McKay and published by Karger Medical and Scientific Publishers. This book was released on 2024 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Fast Facts: Follicular Lymphoma' provides an introduction to follicular lymphoma for healthcare professionals and others with an interest in this blood cancer. It summarizes what is known about the pathophysiology of the disease, and discusses the importance of accurate diagnosis, classification, and risk assessment, together with existing approaches to treatment and monitoring. Looking into the future, it also reviews some of the therapies in development, which may ultimately improve quality of life and ensure better outcomes for patients with FL.

Fast Facts: Cutaneous T-cell Lymphoma

Author : Paul L Haun
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 1912776308
Total Pages : 112 pages
Book Rating : 4.9/5 (127 download)

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Book Synopsis Fast Facts: Cutaneous T-cell Lymphoma by : Paul L Haun

Download or read book Fast Facts: Cutaneous T-cell Lymphoma written by Paul L Haun and published by Karger Medical and Scientific Publishers. This book was released on 2019-04-25 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cutaneous T-cell lymphoma (CTCL) has been described as a 'great mimicker'. The correct diagnosis hinges on effective collaboration between clinicians and pathologists to correlate pathological and clinical findings. The patient's history, lesion description and diagnostic work-up will help the pathologist interpret the histopathology, whilst the clinician’s diagnosis is aided by a clear understanding the terminology used in the pathology report. The treatment of early and advanced mycosis fungoides and its variants is potentially lifelong, with patients typically cycling among treatments, interspersed with periods of expectant therapy providing palliation and symptomatic relief. Effective management requires knowledge of the wide range of options, how they are used, and their side-effect profile, in order to tailor treatment to the individual patient.