Facing Immunotherapy

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Cancer Immunology and Immunotherapy

Author : Mansoor M. Amiji
Publisher : Elsevier
ISBN 13 : 0128233974
Total Pages : 548 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Cancer Immunology and Immunotherapy by : Mansoor M. Amiji

Download or read book Cancer Immunology and Immunotherapy written by Mansoor M. Amiji and published by Elsevier. This book was released on 2021-08-27 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy examines the challenges of delivering immuno-oncology therapies. Immuno-oncology (IO) is a growing field of medicine at the interface of immunology and cancer biology leading to development of novel therapeutic approaches, such as chimeric antigen receptor T-cell (CAR-T) and immune checkpoint blockade antibodies, that are clinically approved approaches for cancer therapy. Although currently approved IO approaches have shown tremendous promise for select types of cancers, broad application of IO strategies could even further improve the clinical success, especially for diseases such as pancreatic cancer, brain tumors where the success of IO so far has been limited. Nanotechnology-based targeted delivery strategies could improve the delivery efficiency of IO agents as well as provide additional avenues for novel therapeutic and vaccination strategies. Additionally, a number of locally-administered immunogenic scaffolds and therapeutic strategies, such as the use of STING agonist, could benefit from rationally designed biomaterials and delivery approaches. Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy creates a comprehensive treaty that engages the scientific and medical community who are involved in the challenges of immunology, cancer biology, and therapeutics with possible solutions from the nanotechnology and drug delivery side. Comprehensive treaty covering all aspects of immuno-oncology (IO) Novel strategies for delivery of IO therapeutics and vaccines Forecasting on the future of nanotechnology and drug delivery for IO

Immunotherapy – A Novel Facet of Modern Therapeutics

Author : Sujata P. Sawarkar
Publisher : Springer Nature
ISBN 13 : 9811590389
Total Pages : 267 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Immunotherapy – A Novel Facet of Modern Therapeutics by : Sujata P. Sawarkar

Download or read book Immunotherapy – A Novel Facet of Modern Therapeutics written by Sujata P. Sawarkar and published by Springer Nature. This book was released on 2020-12-16 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book illustrates the significance and relevance of immunotherapy in modern-day therapeutics. Focusing on the application of immunotherapy in oncology, neurodegenerative and autoimmune diseases, it discusses the drug delivery systems, and pre-clinical and clinical methodologies for immunotherapy-based drugs. It also comprehensively reviews various aspects of immunotherapy, such as regulatory affairs, quality control, safety, and pharmacovigilance. Further, the book discusses the in vitro validation of therapeutic strategies prior to patient application and management of immunotherapy-related side effects and presents case studies demonstrating the design and development (pre-clinical to clinical) of immunotherapy for various diseases. It also describes various design considerations and the scale-up synthesis of immunotherapeutics and screening methods. Lastly, it explores the important aspect of cost-effectiveness and rational immunotherapy strategies.

SITC’s Guide to Managing Immunotherapy Toxicity

Author : Marc S. Ernstoff, MD
Publisher : Springer Publishing Company
ISBN 13 : 0826172156
Total Pages : 275 pages
Book Rating : 4.8/5 (261 download)

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Book Synopsis SITC’s Guide to Managing Immunotherapy Toxicity by : Marc S. Ernstoff, MD

Download or read book SITC’s Guide to Managing Immunotherapy Toxicity written by Marc S. Ernstoff, MD and published by Springer Publishing Company. This book was released on 2019-03-15 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Society for Immunotherapy of Cancer's handbook,SITC’s Guide to Managing Immunotherapy Toxicity, is a practical reference to managing side effects associated with FDA-approved cancer immunotherapy drugs. Separated into two parts, Part I contains chapter-based overviews of immune checkpoint inhibitors in the clinic, starting with anti-CTLA4 agents, anti-PD1/PD-L1 agents, and approved immunotherapeutic combinations. These chapters cover relevant mechanisms of action, indications, and toxicities seen while combating early, advanced, and metastatic stages in cancer patients. Part II is structured by common and uncommon toxicities that affect major organ sites throughout the body. It begins with a general summary of principles and management options followed by chapters focusing on specific toxicities such as rash and mucosal irritation, muscle and joint toxicity, diarrhea and colitis, pneumonitis, endocrine toxicities, neurological toxicities, cardiac toxicity, renal toxicity, hematologic toxicity, and ocular toxicities. Each chapter provides guidance on how to assess and treat the toxicity and how to support the patient through acute and chronic effects with detailed summary tables for quick reference. Part II concludes with chapters covering management of special patient populations, including patients with autoimmune disease and geriatric patients, treatment and management of fatigue, and a final chapter dedicated to cost effectiveness and the toll of financial toxicity on patients and caregivers. With chapters written by world-recognized leaders in the immuno-oncology field, this text provides thorough coverage of the toxicity and management of adverse effects for immune checkpoint inhibitors. It is an indispensable resource for clinical oncologists, emergency physicians, hospitalists and other medical practitioners in both the hospital and community clinic settings, especially as the use of immune checkpoint inhibitors becomes a fixture in oncology care. Key Features: Outlines strategies for treating high-risk patients facing an acute or chronic side effect to immunotherapy Provides numerous tables that condense and highlight pertinent information for quick reference Describes the various clinical presentations and toxic reactions caused by immunotherapy Purchase includes access to the eBook for use on most mobile devices or computer

Facing Immunotherapy

Author : Justine Cohen
Publisher :
ISBN 13 : 9781677234516
Total Pages : 369 pages
Book Rating : 4.2/5 (345 download)

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Book Synopsis Facing Immunotherapy by : Justine Cohen

Download or read book Facing Immunotherapy written by Justine Cohen and published by . This book was released on 2019-12-18 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Facing Immunotherapy is for anyone whose life is affected by cancer and who is considering (or is receiving) immunotherapy. Written by leading physicians in their fields, Facing Immunotherapy combines top-tier medical information and compassionate counsel on the use and tolerability of immunotherapies, with a caring and sensible approach to the emotional aspects of living with cancer treatment and its complications. This book provides easily readable and trustworthy information, which is divided amongst twenty-six chapters that ask and answer pertinent questions about immunotherapy and its medical, surgical, and psychiatric/psychological components. A glossary of terms provides important background information to readers (e.g., about the disease, nutrition, diet, exercise, and risk-reduction); online resources and references are also offered. Each chapter is accompanied by selected reference and internet resources as well as illustrations and photographs.

Ovarian Cancer Immunotherapy

Author : Samir A. Farghaly
Publisher : Oxford University Press
ISBN 13 : 019024822X
Total Pages : 273 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis Ovarian Cancer Immunotherapy by : Samir A. Farghaly

Download or read book Ovarian Cancer Immunotherapy written by Samir A. Farghaly and published by Oxford University Press. This book was released on 2018-08-31 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ovarian Cancer Immunotherapy provides a broad overview of several aspects of basic sciences, and clinical and therapeutic aspects of immunotherapy for ovarian cancer, as well as state-of-the-art information on molecular genetics and biology. Chapters are written by a team of expert contributors from around the world and explore topics such as antibody therapeutics for ovarian carcinoma, emerging serum biomarkers, ovarian cancer immunity, adoptive cell immunotherapy, the biology of dendritic cells, the role of growth factors, and more. Readers will also gain a better understanding of the molecular and cellular events that underlie ovarian cancer immunology. This book is an ideal resource for clinicians, basic medical scientists, graduate basic medical science students, and medical students caring for patients with ovarian cancer, including attending surgeons and physicians, and clinical fellows and residents in the disciplines of gynecologic oncology, medical oncology, and surgical oncology.

NK Cells in Cancer Immunotherapy: Successes and Challenges

Author : Anahid Jewett
Publisher : Academic Press
ISBN 13 : 0128226269
Total Pages : 496 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis NK Cells in Cancer Immunotherapy: Successes and Challenges by : Anahid Jewett

Download or read book NK Cells in Cancer Immunotherapy: Successes and Challenges written by Anahid Jewett and published by Academic Press. This book was released on 2022-12-06 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: NK Cells in Cancer Immunotherapy: Successes and Challenges explains the latest immunotherapeutic strategies, focusing on NK cells to allow the best and precise combination treatments to cancer patients. The book provides existing background knowledge in the field of immunotherapy and discusses future areas of research required to carry out cutting-edge, validated therapies. Chapters cover advances in immunotherapeutic strategies, in particular, the use of NK cells with and without T-cell therapy in the treatment of cancer. The book is a valuable resource for cancer researchers, oncologists, graduate students and those interested in learning more about novel strategies to treat cancer patients. Immunotherapy is fast becoming the method of choice for cancer therapy. Although remarkable advances have been made in the field of immunotherapy, there are significant challenges and difficulties ahead since many of the current immunotherapeutic strategies do not provide long-lasting treatment strategies, and therefore are not very effective. - Covers CAR/T and CAR/NK and adoptive NK cell therapy with and without T cell therapies - Discusses basic biology of NK cells and mouse models of human cancers and the role of NK cells in metastatic cancer and in cancer stem cells - Encompasses information on combination therapies using check point inhibition, adoptive transfer of cytotoxic effector cells, chemotherapeutic drugs and activating and inhibitory antibodies

Cancer Immunotherapy

Author : Tyler J. Curiel
Publisher : Springer Science & Business Media
ISBN 13 : 1461447321
Total Pages : 486 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Cancer Immunotherapy by : Tyler J. Curiel

Download or read book Cancer Immunotherapy written by Tyler J. Curiel and published by Springer Science & Business Media. This book was released on 2012-11-07 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work will provide a historical perspective on tumor immunotherapy, discuss fundamental mechanisms of failed tumor rejection, look at passive strategies to boost anti-tumor immunity, as well as have an in-depth look at active strategies to boost anti-tumor immunity.

CDC Yellow Book 2018: Health Information for International Travel

Author : Centers for Disease Control and Prevention CDC
Publisher : Oxford University Press
ISBN 13 : 0190628634
Total Pages : 705 pages
Book Rating : 4.1/5 (96 download)

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Book Synopsis CDC Yellow Book 2018: Health Information for International Travel by : Centers for Disease Control and Prevention CDC

Download or read book CDC Yellow Book 2018: Health Information for International Travel written by Centers for Disease Control and Prevention CDC and published by Oxford University Press. This book was released on 2017-04-17 with total page 705 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.

Cancer Immunotherapy Principles and Practice

Author : Lisa H. Butterfield
Publisher :
ISBN 13 : 9781620700976
Total Pages : 0 pages
Book Rating : 4.7/5 (9 download)

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Book Synopsis Cancer Immunotherapy Principles and Practice by : Lisa H. Butterfield

Download or read book Cancer Immunotherapy Principles and Practice written by Lisa H. Butterfield and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part 1: Intratumoral Signatures Associated With Immune Responsiveness

Cancer Immunotherapies: From Efficacy to Resistance Mechanisms

Author : Morten Hansen
Publisher : Frontiers Media SA
ISBN 13 : 2889764419
Total Pages : 470 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Cancer Immunotherapies: From Efficacy to Resistance Mechanisms by : Morten Hansen

Download or read book Cancer Immunotherapies: From Efficacy to Resistance Mechanisms written by Morten Hansen and published by Frontiers Media SA. This book was released on 2022-06-29 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Koguchi receives funding from Tesaro, a GSK company, Bristol-Myers Squibb, and Shimadzu Corporation.. Dr. Vujanovic is a co-inventor of a methodology licensed to INmune Bio, Inc. where a selective inhibitor of soluble TNF can be used to prevent or treat malignancies. Dr. Hansen is the recipient of a private grant from Eurostars Eureka. The other Topic Editors declare no competing interests.

Immunotherapy of Hepatocellular Carcinoma

Author : Tim F. Greten
Publisher : Springer
ISBN 13 : 9783319879116
Total Pages : 0 pages
Book Rating : 4.8/5 (791 download)

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Book Synopsis Immunotherapy of Hepatocellular Carcinoma by : Tim F. Greten

Download or read book Immunotherapy of Hepatocellular Carcinoma written by Tim F. Greten and published by Springer. This book was released on 2018-08-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book we provide insights into liver – cancer and immunology. Experts in the field provide an overview over fundamental immunological questions in liver cancer and tumorimmunology, which form the base for immune based approaches in HCC, which gain increasing interest in the community due to first promising results obtained in early clinical trials. Hepatocellular carcinoma (HCC) is the third most common cause of cancer related death in the United States. Treatment options are limited. Viral hepatitis is one of the major risk factors for HCC, which represents a typical “inflammation-induced” cancer. Immune-based treatment approaches have revolutionized oncology in recent years. Various treatment strategies have received FDA approval including dendritic cell vaccination, for prostate cancer as well as immune checkpoint inhibition targeting the CTLA4 or the PD1/PDL1 axis in melanoma, lung, and kidney cancer. Additionally, cell based therapies (adoptive T cell therapy, CAR T cells and TCR transduced T cells) have demonstrated significant efficacy in patients with B cell malignancies and melanoma. Immune checkpoint inhibitors in particular have generated enormous excitement across the entire field of oncology, providing a significant benefit to a minority of patients.

Facing Autism

Author : Lynn M. Hamilton
Publisher : WaterBrook
ISBN 13 : 0307569039
Total Pages : 386 pages
Book Rating : 4.3/5 (75 download)

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Book Synopsis Facing Autism by : Lynn M. Hamilton

Download or read book Facing Autism written by Lynn M. Hamilton and published by WaterBrook. This book was released on 2009-09-30 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Don't Let Autism Have the Last Word in Your Child's Life. Perhaps one of the most devastating things you can learn as a parent is that your child has been diagnosed with autism. A multifaceted disorder, autism has long baffled parents and professionals alike. At one time, doctors gave parents virtually no hope for combating the disorder. But in recent years, new treatments and therapies have demonstrated that improvement is possible. With intensive, early intervention, some children have recovered from autism and have been integrated into school, indistinguishable from their peers. Discover ten things you can do to begin battling your child's autism right now. See why Applied Behavior Analysis has become parents' treatment of choice, and examine its impressive results. Get information on cutting-edge biomedical treatments such as secretin and immunotherapy. Learn how dietary intervention can positively impact your child's behavior. Find out what additional therapies can offer - including sensory and auditory integration. Explore loving ways to keep your family together when your world is torn apart. Children with autism do have the possibility to improve greatly, and some even overcome the effects of autism, if appropriate therapies are begun early enough. Discover the steps you can take today to begin the fight for your child's future in Facing Autism.

Progress in Cancer Immunotherapy

Author : Shuren Zhang
Publisher : Springer
ISBN 13 : 9401775559
Total Pages : 293 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis Progress in Cancer Immunotherapy by : Shuren Zhang

Download or read book Progress in Cancer Immunotherapy written by Shuren Zhang and published by Springer. This book was released on 2016-05-30 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides readers an extensive overview of recent progress in basic and clinical research on cancer immunotherapy. Thanks to rapid advances in molecular biology and immunology, it has become increasingly evident that cancer growth is influenced by host immune responses. With the success of a number of clinical trials, immunotherapy has become a promising treatment modality of cancer. This book covers five major topics, including monoclonal antibodies, biological response modifiers, cancer vaccines, adoptive cellular therapy and oncolytic viruses. It also examines the combination of different immune strategies as well as the combination of immunotherapy with other treatments to increase anti-tumor effects. Through the comprehensive discussion of the topic, the book sheds valuable new light on the treatment of tumors.

Regulation of Cancer Immune Checkpoints

Author : Jie Xu
Publisher : Springer Nature
ISBN 13 : 9811532664
Total Pages : 657 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Regulation of Cancer Immune Checkpoints by : Jie Xu

Download or read book Regulation of Cancer Immune Checkpoints written by Jie Xu and published by Springer Nature. This book was released on 2020-03-17 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book systematically reviews the most important findings on cancer immune checkpoints, sharing essential insights into this rapidly evolving yet largely unexplored research topic. The past decade has seen major advances in cancer immune checkpoint therapy, which has demonstrated impressive clinical benefits. The family of checkpoints for mediating cancer immune evasion now includes CTLA-4, PD-1/PD-L1, CD27/CD70, FGL-1/LAG-3, Siglec-15, VISTA (PD-1L)/VSIG3, CD47/SIRPA, APOE/LILRB4, TIGIT, and many others. Despite these strides, most patients do not show lasting remission, and some cancers have been completely resistant to the therapy. The potentially lethal adverse effects of checkpoint blockade represent another major challenge, the mechanisms of which remain poorly understood. Compared to the cancer signaling pathways, such as p53 and Ras, mechanistic studies on immune checkpoint pathways are still in their infancy. To improve the responses to checkpoint blockade therapy and limit the adverse effects, it is essential to understand the molecular regulation of checkpoint molecules in both malignant and healthy cells/tissues. This book begins with an introduction to immune checkpoint therapy and its challenges, and subsequently describes the regulation of checkpoints at different levels. In closing, it discusses recent therapeutic developments based on mechanistic findings, and outlines goals for future translational studies. The book offers a valuable resource for researchers in the cancer immunotherapy field, helping to form a roadmap for checkpoint regulation and develop safer and more effective immunotherapies.

Massachusetts General Hospital Handbook of General Hospital Psychiatry - E-BOOK

Author : Theodore A. Stern
Publisher : Elsevier Health Sciences
ISBN 13 : 0443119325
Total Pages : 2057 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Massachusetts General Hospital Handbook of General Hospital Psychiatry - E-BOOK by : Theodore A. Stern

Download or read book Massachusetts General Hospital Handbook of General Hospital Psychiatry - E-BOOK written by Theodore A. Stern and published by Elsevier Health Sciences. This book was released on 2024-09-05 with total page 2057 pages. Available in PDF, EPUB and Kindle. Book excerpt: For more than 40 years, the Massachusetts General Hospital Handbook of General Hospital Psychiatry has been the gold standard guide to consultation-liaison psychiatry and psychosomatic medicine. Under the editorial leadership of Drs. Theodore A. Stern, Scott R. Beach, Felicia A. Smith, Oliver Freudenreich, Ana-Maria Vranceanu, and Maurizio Fava, the fully revised 8th Edition continues this tradition of excellence for yet another generation of practitioners. In a convenient handbook format, it provides an authoritative, easy-to-understand review of the diagnosis, evaluation, and treatment of psychiatric problems experienced by adults and children with medical and surgical conditions. - Features DSM-5-TR codes throughout, case studies, and practical tips on how to implement the most current and effective pharmacologic therapies as well as cognitive-behavioral approaches. - Includes new chapters on Psychiatric Management of Patients with Pulmonary Conditions; Psychiatric Management of Patients with COVID-19 Infection; Behavioral and Psychopharmacological Management of Unhealthy Habits and Behaviors; Community Psychiatry; Global Mental Health; Care of LGBTQ Patients; and more. - Highlights strategies to enhance coping with medical conditions, resilience, adherence to treatment recommendations, and mindfulness. - Features a new, two-color format for improved readability and visual clarity for tables, diagrams, and illustrations. - An ideal resource for psychiatrists, residents, and fellows, as well as interdisciplinary practitioners who support the work of consultation-liaison psychiatrists and provide independent care to medical/surgical patients with comorbid psychiatric symptoms or conditions.

Detection Methods in Precision Medicine

Author : Mengsu Yang
Publisher : Royal Society of Chemistry
ISBN 13 : 1788017617
Total Pages : 389 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Detection Methods in Precision Medicine by : Mengsu Yang

Download or read book Detection Methods in Precision Medicine written by Mengsu Yang and published by Royal Society of Chemistry. This book was released on 2020-12-14 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will be among the first to cover the detection methods for precision medicine that are set to transform health care in the future.

Dermatologic Principles and Practice in Oncology

Author : Mario E. Lacouture
Publisher : John Wiley & Sons
ISBN 13 : 1118590600
Total Pages : 764 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis Dermatologic Principles and Practice in Oncology by : Mario E. Lacouture

Download or read book Dermatologic Principles and Practice in Oncology written by Mario E. Lacouture and published by John Wiley & Sons. This book was released on 2013-11-26 with total page 764 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book focusing specifically on frequent and frequently disabling side effects involving the skin, hair and nails in cancer patients According to the World Health Organization, there are approximately thirty million people living with a diagnosis of cancer – the majority of whom will receive surgery, systemic therapy, and/or radiation, and who will suffer from dermatologic adverse events. Dermatologists and oncologists are only beginning to grapple with these events, which pose serious quality-of-life issues with so many patients, and will become more prevalent as survival rates improve, thanks in part to new cancer treatments and drug regimens. Concentrating on a topic that has only been briefly touched upon by other texts, this book offers a focused perspective on the clinical presentation, underlying pathophysiologic mechanisms, and management of skin, hair, and nail conditions for oncologists, dermatologists, and allied practitioners. Dermatologic Principles and Practice in Oncology: Conditions of the Skin, Hair, and Nails in Cancer Patients: • Covers in detail the dermatologic adverse events of oncologic therapies, clinical presentations, and treatment recommendations • Enables dermatologists and other practitioners to significantly improve the care of patients with cancer • Addresses the dermatologic adverse events of cancer therapies used globally, of which a large number are found in developing countries • Emphasizes prophylactic measures – based on treatments used and type of cancer – to prevent the appearance of adverse events • Provides built-in discussions on patient education for practical counseling during therapies • Offers rapid-reference sections on topical dermatology drugs The first book to present dermatologic conditions in cancer patients and survivors in a uniform and in-depth manner, Dermatologic Principles and Practice in Oncology is ideal for oncologists, oncology nurses, and dermatologists who wish to take better care of those with adverse skin, hair, and nail conditions.