Experimental Neurosurgery In Animal Models

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Experimental Neurosurgery in Animal Models

Author : Miroslaw Janowski
Publisher : Neuromethods
ISBN 13 : 9781493981229
Total Pages : 268 pages
Book Rating : 4.9/5 (812 download)

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Book Synopsis Experimental Neurosurgery in Animal Models by : Miroslaw Janowski

Download or read book Experimental Neurosurgery in Animal Models written by Miroslaw Janowski and published by Neuromethods. This book was released on 2018-06-22 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a full explanation and technical details to perform surgical techniques properly on small and large animal models. The first six chapters of Experimental Neurosurgery in Animal Models focus primarily on the brain, while the next six chapters concern the spinal cord in rodents. The last four chapters provide a description of operative procedures in large animals. Written for the popular Neuromethods series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory. Authoritative and practical, Experimental Neurosurgery in Animal Models aims to ensure successful results in the further study of this vital field.

Animal Models of Acute Neurological Injuries

Author : Jun Chen
Publisher : Springer Science & Business Media
ISBN 13 : 1603271856
Total Pages : 490 pages
Book Rating : 4.6/5 (32 download)

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Book Synopsis Animal Models of Acute Neurological Injuries by : Jun Chen

Download or read book Animal Models of Acute Neurological Injuries written by Jun Chen and published by Springer Science & Business Media. This book was released on 2008-12-16 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite numerous recent studies and exciting discoveries in the field, only limited treatment is available today for the victims of acute neurological injuries. Animal Models of Acute Neurological Injuries provides a standardized methodology manual designed to eliminate the inconsistent preparations and variability that currently jeopardizes advances in the field. Contributed by top experts and many original developers of the models, each chapter contains a step-by-step, proven procedure and visual aids covering the most commonly used animal models of neurological injury in order to highlight the practical applications of animal models rather than the theoretical issues. This intensive volume presents its readily reproducible protocols with great clarity and consistency to best aid neuroscientists and neurobiologists in laboratory testing and experimentation. Comprehensive and cutting-edge, Animal Models of Acute Neurological Injuries is an ideal guide for scientists and researchers who wish to pursue this vital course of study with the proficiency and precision that the field requires.

Research and Publishing in Neurosurgery

Author : Yücel Kanpolat
Publisher : Springer Science & Business Media
ISBN 13 : 3709167434
Total Pages : 156 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Research and Publishing in Neurosurgery by : Yücel Kanpolat

Download or read book Research and Publishing in Neurosurgery written by Yücel Kanpolat and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Research” and "Publishing” are phrases familiar to all neurosurgeons and neuroscientists. Many young neurosurgeons struggle with them on a trial-and-error basis at first, and there are not structured education programs providing information on standard methods. The European Association of Neurosurgical Societies Research Committee has developed a course on research and publication methods for residents in neurosurgery who have not yet completed training. This supplement includes selected contributions from this course and will serve as an essential handbook providing basic tools to guide research and publication work, presenting time-saving advice, and resulting in the most beneficial contributions in experimental and clinical research.

International Animal Research Regulations

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309252113
Total Pages : 102 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis International Animal Research Regulations by : National Research Council

Download or read book International Animal Research Regulations written by National Research Council and published by National Academies Press. This book was released on 2012-06-26 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animals are widely used in neuroscience research to explore biological mechanisms of nervous system function, to identify the genetic basis of disease states, and to provide models of human disorders and diseases for the development of new treatments. To ensure the humane care and use of animals, numerous laws, policies, and regulations are in place governing the use of animals in research, and certain animal regulations have implications specific to neuroscience research. To consider animal research regulations from a global perspective, the IOM Forum on Neuroscience and Nervous System Disorders, in collaboration with the National Research Council and the Institute for Laboratory Animal Research, held a workshop in Buckinghamshire, UK, July 26-27, 2011. The workshop brought together neuroscientists, legal scholars, administrators, and other key stakeholders to discuss current and emerging trends in animal regulations as they apply to the neurosciences. This document summarizes the workshop.

Brain Neurotrauma

Author : Firas H. Kobeissy
Publisher : CRC Press
ISBN 13 : 1466565993
Total Pages : 718 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Brain Neurotrauma by : Firas H. Kobeissy

Download or read book Brain Neurotrauma written by Firas H. Kobeissy and published by CRC Press. This book was released on 2015-02-25 with total page 718 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.

Brain Stimulation

Author : Yasin Temel
Publisher : Elsevier Inc. Chapters
ISBN 13 : 0128080086
Total Pages : 21 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Brain Stimulation by : Yasin Temel

Download or read book Brain Stimulation written by Yasin Temel and published by Elsevier Inc. Chapters. This book was released on 2013-11-11 with total page 21 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deep brain stimulation (DBS) as a therapy in neurological and psychiatric disorders is applied widely. In this respect, DBS in animal models is performed to study the underlying mechanisms and to evaluate new indications and technology. This chapter summarizes our experience with DBS in animal models, and relevant literature. Electrodes for DBS in animal models have been developed using translational principles, to allow DBS under anesthesia and in freely moving conditions. The stimulation parameters have been adjusted for the animals using current density calculations. This paradigm of experimental DBS has been validated in a variety of animal models of neurological and psychiatric disorders. During the process of development and validation of DBS in animal models, specific problems have been encountered, which are discussed in the chapter. DBS in animal models is an adequate paradigm to explore the underlying mechanisms and new indications for DBS, and to refine DBS technology.

Translational Research in Traumatic Brain Injury

Author : Daniel Laskowitz
Publisher : CRC Press
ISBN 13 : 1498766579
Total Pages : 388 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Translational Research in Traumatic Brain Injury by : Daniel Laskowitz

Download or read book Translational Research in Traumatic Brain Injury written by Daniel Laskowitz and published by CRC Press. This book was released on 2016-04-21 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme

Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 030916785X
Total Pages : 223 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research by : National Research Council

Download or read book Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 2003-08-22 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.

Step by Step Experimental Pinealectomy Techniques in Animals for Researchers

Author : Mehmet Turgut
Publisher : Nova Science Publishers
ISBN 13 : 9781628081343
Total Pages : 0 pages
Book Rating : 4.0/5 (813 download)

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Book Synopsis Step by Step Experimental Pinealectomy Techniques in Animals for Researchers by : Mehmet Turgut

Download or read book Step by Step Experimental Pinealectomy Techniques in Animals for Researchers written by Mehmet Turgut and published by Nova Science Publishers. This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains a varied collection of chapters covering pinealectomy techniques used in current neuroscience research from over 19 internationally recognised scientists. In a total of 8 chapters, this book presents general information in pinealectomy covering topics from anatomy and histology of the pineal gland in animals to the melatonin system and different surgical techniques. This book forms an essential reference for anyone working in neuroscience, from beginner students to experienced researchers since basic information on different pinealectomy procedures used in animal models can be extremely hard to find.

Step by Step Experimental Pinealectomy Techniques in Animals for Researchers

Author : Mehmet Turgut
Publisher : Nova Biomedical Books
ISBN 13 : 9781628081589
Total Pages : 192 pages
Book Rating : 4.0/5 (815 download)

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Book Synopsis Step by Step Experimental Pinealectomy Techniques in Animals for Researchers by : Mehmet Turgut

Download or read book Step by Step Experimental Pinealectomy Techniques in Animals for Researchers written by Mehmet Turgut and published by Nova Biomedical Books. This book was released on 2014-05-14 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains a varied collection of chapters covering pinealectomy techniques used in current neuroscience research from over 19 internationally recognized scientists. In a total of 8 chapters, this book presents general information in pinealectomy covering topics from anatomy and histology of the pineal gland in animals to the melatonin system and different surgical techniques. This book forms an essential reference for anyone working in neuroscience, from beginner students to experienced researchers since basic information on different pinealectomy procedures used in animal models can be extremely hard to find.

Surgical Research

Author : Wiley W. Souba
Publisher : Academic Press
ISBN 13 : 9780126553307
Total Pages : 1526 pages
Book Rating : 4.5/5 (533 download)

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Book Synopsis Surgical Research by : Wiley W. Souba

Download or read book Surgical Research written by Wiley W. Souba and published by Academic Press. This book was released on 2001-01-25 with total page 1526 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contributors. -- Foreword. -- Preface. -- Getting Started. -- Assessing Available Information. -- Organizing and Preliminary Planning for Surgical Research -- Writing a Protocol: Animals, Humans, and Use of Biologic, Chemical, and Radiologic Agents. -- Grantsmanship. -- Informed Consent and the Protection of Human Research Subjects: Historical Perspectives and Guide to Current United States Regulations. -- Animal Care and Maintenance. -- Funding Strategies and Agencies: Academic-Industrial Relationships; Intellectual Property. -- Statistical Considerations. -- Use of Nonexperimental Studies to Evaluate Surgical Procedures and Other Interventions: The Challenge of Risk Adjustment. -- Measuring Surgical Outcomes. -- Design of Clinical Trials. -- Using Administrative Data for Clinical Research. -- Research in the Intensive Care Unit: Ethical and Methodological Issues. -- Research in the Operating Room. -- Effects of Age and Gender. -- Strategies, Principles, and Techniques Using Transgeni ...

Animal Models and the Unity of Neuroscience

Author : Nina A. Atanasova
Publisher :
ISBN 13 :
Total Pages : 161 pages
Book Rating : 4.:/5 (89 download)

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Book Synopsis Animal Models and the Unity of Neuroscience by : Nina A. Atanasova

Download or read book Animal Models and the Unity of Neuroscience written by Nina A. Atanasova and published by . This book was released on 2014 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contemporary neurobiology abounds with multiple experimental protocols and procedures aiming to study identical phenomena. This state of affairs seems to put in jeopardy the integration of experimental results and the extrapolation of laboratory knowledge to natural world phenomena. The problem is further complicated when knowledge produced through animal experimentation is extended to humans. My thesis is that the multiplicity of protocols fosters rather than precludes progress in neurobiology. It is especially valued when the results of different experiments converge. In these cases, the validity of knowledge claims increases. Converging experimental results get integrated. To date, no comprehensive philosophical analysis of animal experimentation in neurobiology exists. For this reason I analyze the functions of animal models in experimental neurobiology. I argue that even though animal models are related to model and experimental organisms, in the case of neurobiology, they are better conceptualized as experimental systems rather than as a subclass of the other two classes of biological models. In a case study, I trace the developments of and the variations on the basic design of Morris water maze experiments to exemplify the motivation for producing variations on basic experimental protocols. Ultimately, I defend a view of the structure of experimental neurobiology which I call optimistic pluralism. It is an extension of the so called perspectival pluralism according to which the integration of multiple partial perspectives employed in the study of any given phenomenon maximizes the knowledge about this phenomenon. It is optimistic because it justifies the possibility for multiple partial perspectives to converge and be integrated in order to provide knowledge about complex phenomena. This view justifies the desirability of multiple experimental protocols in contemporary neurobiology because it values the multiplicity of perspectives they provide.

Experimental Gene Therapy in Animal Models of Neurological Diseases

Author : Graham Morrissey
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (642 download)

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Book Synopsis Experimental Gene Therapy in Animal Models of Neurological Diseases by : Graham Morrissey

Download or read book Experimental Gene Therapy in Animal Models of Neurological Diseases written by Graham Morrissey and published by . This book was released on 2001 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Neurovascular Surgery

Author : Robert F. Spetzler
Publisher : Thieme
ISBN 13 : 1604067608
Total Pages : 2918 pages
Book Rating : 4.6/5 (4 download)

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Book Synopsis Neurovascular Surgery by : Robert F. Spetzler

Download or read book Neurovascular Surgery written by Robert F. Spetzler and published by Thieme. This book was released on 2015-04-15 with total page 2918 pages. Available in PDF, EPUB and Kindle. Book excerpt: The complex, highly technological field of neurovascular surgery is quickly expanding, encompassing traditional surgical approaches, as well as endovascular and neurointerventional techniques. The last decade has seen increased cross-specialty interest in utilizing minimally invasive techniques to help prevent and treat cerebrovascular disease. Concurrently, there has been important research analyzing the efficacy of surgical methods versus endovascular approaches and the clip versus coil discussion is covered herein. Written by 21st Century pioneers in the field, this second, cutting-edge edition offers the latest science throughout 1,400 pages and a remarkable video library covering anatomy, diagnosis, epidemiology, history, treatment indications, technical nuances, outcomes, and complications. Internationally renowned experts from across the globe share clinical pearls and best practices,from the research lab to the ER to the OR. Medical, surgical, endovascular, cerebral revascularization, bypass surgery, radiation therapy, and other procedures are covered in depth. Evidence-based and transdisciplinary, the second edition covers the full spectrum of neurovascular pathologies,preoperatively and postoperatively,including: Ischemic Stroke and Vascular Insufficiency Cerebral and Spinal Aneurysms Cerebral and Spinal Arteriovenous Fistulae and Malformations Vascular Tumors Carotid Artery Disease Moya-Moya Disease Moya-Moya Disease Revascularization techniques Organized into 11 primary sections, 99 richly illustrated chapters, and more than 140 videos, this volume is an invaluable, one-stop reference tool. It is a must-have for general, vascular and endovascular neurosurgeons; interventional radiologists; neurologists; critical care practitioners; and neuro-rehabilitation specialists.

Handbook of Animal Models in Neurological Disorders

Author : Colin R Martin
Publisher : Elsevier
ISBN 13 : 0323898866
Total Pages : 708 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Handbook of Animal Models in Neurological Disorders by : Colin R Martin

Download or read book Handbook of Animal Models in Neurological Disorders written by Colin R Martin and published by Elsevier. This book was released on 2022-11-29 with total page 708 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Animal Models in Neurological Disorders will better readers' understanding of a large variety of animal models and their applicability in studying a number of neurological disorders. Featuring sections on brain injury, stroke and neuroinflammation, this volume discusses in detail the utility, success and pitfalls of multiple models for each condition. Multiple disorders are covered, ranging from neurodegenerative diseases like Alzheimer's, Parkinson's, and ALS, to multiple sclerosis, headache, migraine, and others. With expert authors, this book has applicability for anyone pursuing neuroscience or biomedical research working to better understand, study and ultimately treat neurological dysfunction. - Summarizes animal models for a variety of neurological conditions - Contains chapter abstracts, key facts, a dictionary and a summary - Covers both neurodegenerative diseases and other neurological conditions - Compares and contrasts different models and experimental systems - Includes sections on Alzheimer's, Parkinson's, brain injury, migraine, multiple sclerosis, and more

Neuromorphic Olfaction

Author : Krishna C. Persaud
Publisher : CRC Press
ISBN 13 : 1439871728
Total Pages : 237 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Neuromorphic Olfaction by : Krishna C. Persaud

Download or read book Neuromorphic Olfaction written by Krishna C. Persaud and published by CRC Press. This book was released on 2016-04-19 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many advances have been made in the last decade in the understanding of the computational principles underlying olfactory system functioning. Neuromorphic Olfaction is a collaboration among European researchers who, through NEUROCHEM (Fp7-Grant Agreement Number 216916)-a challenging and innovative European-funded project-introduce novel computing p

Recognition and Alleviation of Distress in Laboratory Animals

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309108179
Total Pages : 137 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Recognition and Alleviation of Distress in Laboratory Animals by : National Research Council

Download or read book Recognition and Alleviation of Distress in Laboratory Animals written by National Research Council and published by National Academies Press. This book was released on 2008-04-10 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific advances in our understanding of animal physiology and behavior often require theories to be revised and standards of practice to be updated to improve laboratory animal welfare. This new book from the Institute for Laboratory Animal Research (ILAR) at the National Research Council, Recognition and Alleviation of Distress in Laboratory Animals, focuses on the stress and distress which is experienced by animals when used in laboratory research. This book aims to educate laboratory animal veterinarians; students, researchers, and investigators; animal care staff, as well as animal welfare officers on the current scientific and ethical issues associated with stress and distress in laboratory animals. It evaluates pertinent scientific literature to generate practical and pragmatic guidelines. Recognition and Alleviation of Distress in Laboratory Animals focuses specifically on the scientific understanding of the causes and the functions of stress and distress, the transformation of stress to distress, and the identification of principles for the recognition and alleviation of distress. This book discusses the role of humane endpoints in situations of distress and principles for the minimization of distress in laboratory animals. It also identifies areas in which further scientific investigation is needed to improve laboratory animal welfare in order to adhere to scientific and ethical principles that promote humane care and practice.