Experimental Methods in Organic Fluorine Chemistry

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Publisher : Routledge
ISBN 13 : 1351449230
Total Pages : 278 pages
Book Rating : 4.3/5 (514 download)

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Book Synopsis Experimental Methods in Organic Fluorine Chemistry by : Tomoya Kitazume

Download or read book Experimental Methods in Organic Fluorine Chemistry written by Tomoya Kitazume and published by Routledge. This book was released on 2019-06-14 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the fields of biologically active materials and functional materials, fluorinated organic materials are becoming a focus of significant interest. Over the past decade synthetic methodologies and reagents in fluorine chemistry have been developed, especially stereocontrolled synthetic methods, enzymatic resolution to synthesize enantiomers, fluoromethylated reagents, and fluorination reagents. These methods have contributed to the opening of new pathways for fluorinated materials. However, few fluorinated materials have been put to commercial use. Furthermore, there remain problems to be solved, such as the handling of the materials, availability of reagents and selectivity (stereo-, regio-, and/or chemoselectivity). Research chemists, technical engineers, and graduate students in all branches of chemistry, pharmaceutics, and material science interested in fluorinated materials need to know detailed experimental procedures of how to synthesize the target fluorinated materials. This volume summarizes the chemical and microbial methods for obtaining functionalized fluorinated materials for use as building blocks; detailed experimental methods (reaction conditions, solvent, temperature, handling techniques, etc.); and the stereoview (possible absolute configuration) of the structures with spectral data. Mono-, di-, tri-, and polyfluorinated materials derived from fluorinating agents, fluoromethylated reagents and building blocks are summarized. A chemical name index, molecular formula index, and reagent index are also included. The publication of this monograph will provide access to the enormous possibilities in fluorine chemistry, biological material chemistry, and functionalized material chemistry.

Chemistry of Organic Fluorine Compounds

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Author :
Publisher : Prentice Hall
ISBN 13 : 9780131316737
Total Pages : 903 pages
Book Rating : 4.3/5 (167 download)

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Book Synopsis Chemistry of Organic Fluorine Compounds by : Milos Hudlicky

Download or read book Chemistry of Organic Fluorine Compounds written by Milos Hudlicky and published by Prentice Hall. This book was released on 1992 with total page 903 pages. Available in PDF, EPUB and Kindle. Book excerpt: This republication of an established classic coincides with a surge in the indistrial development of fluorine chemistry. Comprehensive and authoritative, it provides finger tip access to methods for introducing small or large numbers of fluorine atoms into organic chemistry. Serving as a practical bench manual and source book for theoretical and industrial knowledge, the reference provides 3,857 references to the original literature; 1,520 illustrated equations indicating reactions and yields of fluorinated products; more than 200 detailed experimental procedures indicating types of reagent that can be used, types of compounds with which they react, and types of products that can be prepared; over 200 tables of highly relevant data; and much more.

Efficient Preparations of Fluorine Compounds

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 111807856X
Total Pages : 490 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Efficient Preparations of Fluorine Compounds by : Herbert W. Roesky

Download or read book Efficient Preparations of Fluorine Compounds written by Herbert W. Roesky and published by John Wiley & Sons. This book was released on 2012-11-06 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: The definitive guide to creating fluorine-based compounds—and the materials of tomorrow Discovered as an element by the French chemist Henri Moissan in 1886, through electrolysis of potassium fluoride in anhydrous hydrogen fluoride—"le fluor," or fluorine, began its chemical history as a substance both elusive and dangerous. With a slight pale yellow hue, fluorine is at room temperature a poisonous diatomic gas. Resembling a spirit from a chemical netherworld, fluorine is highly reactive, difficult to handle, yet very versatile as a reagent—with the power to form compounds with almost any other element. Comprising 20% of pharmaceutical products and 30% of agrochemical compounds, as well as playing a key role in electric cars, electronic devices, and space technology, compounds containing fluorine have grown in importance across the globe. Learning how to safely handle fluorine in the preparation of innovative new materials—with valuable new properties—is of critical importance to chemists today. Bringing together the research and methods of leading scientists in the fluorine field, Efficient Preparations of Fluorine Compounds is the definitive manual to creating, and understanding the reaction mechanisms integral to a wide variety of fluorine compounds. With sixty-eight contributed chapters, the book's extensive coverage includes: Preparation of Elemental Fluorine Synthesis Methods for Exotic Inorganic Fluorides with Varied Applications Introduction of Fluorine into Compounds via Electrophilic and Nucleophilic Reactions Direct Fluorination of Organic Compounds with Elemental Fluorine Efficient Preparations of Bioorganic Fluorine Compounds Asymmetric Fluorocyclization Reactions Preparations of Rare Earth Fluorosulfides and Oxyfluorosulfides The book offers methods and results that can be reproduced by students involved in advanced studies, as well as practicing chemists, pharmaceutical scientists, biologists, and environmental researchers. The only chemical resource of its kind, Efficient Preparations of Fluorine Compounds—from its first experiment to its last—is a unique window into the centuries old science of fluorine and the limitless universe of fluorine-based compounds.

Fluorine Chemistry for Organic Chemists

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Author :
Publisher : Oxford University Press
ISBN 13 : 0198030142
Total Pages : 145 pages
Book Rating : 4.1/5 (98 download)

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Book Synopsis Fluorine Chemistry for Organic Chemists by : Milos Hudlic'ky

Download or read book Fluorine Chemistry for Organic Chemists written by Milos Hudlic'ky and published by Oxford University Press. This book was released on 2000-04-20 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a synthesis of two of Hudlicky's earlier books outlining the many unpredictable properties of fluorine and its compounds that are not analogous to the properties of any other halogens and their compounds. It is divided into two separate sections, the first presenting peculiar reactions as problems to be solved. Each reaction can be analyzed in the lab without the help of the second section, however if a solution is not easily reached, the second section provides discussion of the problems, outlining the products of the reactions and their mechanisms. Among the 105 reactions outlined are the introduction of fluorine into organic molecules, reduction and oxidation of fluorine compounds, reactions of fluorocompounds with halogens and their derivatives, nitration, acid catalyzed reactions, organometallic syntheses, and pyrolyses. The reactions are documented in the experimental material of the earlier volumes and will be important background knowledge for anyone working in organic chemistry.

Organic and Inorganic Fluorine Chemistry

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Author :
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110659506
Total Pages : 846 pages
Book Rating : 4.1/5 (16 download)

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Book Synopsis Organic and Inorganic Fluorine Chemistry by : Axel Haupt

Download or read book Organic and Inorganic Fluorine Chemistry written by Axel Haupt and published by Walter de Gruyter GmbH & Co KG. This book was released on 2021-03-22 with total page 846 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic and Inorganic Fluorine Chemistry provides an introduction to fluorine chemistry and an overview of the most important fluorinated compounds and general preparation techniques. The book is divided into three parts, covering general aspects, inorganic fluorides and fluoroorganic compounds. The inorganic part presents the most important element fluorides and oxyfluorides, their preparation as well as their most characteristic properties. The organic section focuses on the different types of fluorination and the corresponding reagents. The application of these techniques is discussed for many different types of substrates. The book addresses advanced students in chemistry as well as researchers in academia and industry. The readers will benefit from a large number of original references which give access to further information. In addition, study questions at the end of each chapter will help to repeat and internalise the most important aspects.

Modern Fluoroorganic Chemistry

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 3527604197
Total Pages : 320 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Modern Fluoroorganic Chemistry by : Peer Kirsch

Download or read book Modern Fluoroorganic Chemistry written by Peer Kirsch and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this handbook, Peer Kirsch clearly shows that this exciting field is no longer an exotic area of research. Aimed primarily at synthetic chemists wanting to gain a deeper understanding of the fascinating implications of including the highly unusual element fluorine in organic compounds, the main part of the book presents a wide range of synthetic methodologies and the experimental procedures selected undeniably show that this can be done with standard laboratory equipment. To round off, the author looks at fluorous chemistry and the applications of organofluorine compounds in liquid crystals, polymers and more besides. This long-awaited book represents an indispensable source of high quality information for everyone working in the field.

Organic Fluorine Compounds Prepared by the Electrochemical Method Literature Survey, 1950-July 1959

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Author :
Publisher :
ISBN 13 :
Total Pages : 44 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Organic Fluorine Compounds Prepared by the Electrochemical Method Literature Survey, 1950-July 1959 by : Sarah Ann Shahan

Download or read book Organic Fluorine Compounds Prepared by the Electrochemical Method Literature Survey, 1950-July 1959 written by Sarah Ann Shahan and published by . This book was released on 1960 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt: References to the literature concerning electrochemical fluorination of organic compounds for the period 1950 - July 1959 have been compiled. A total of 119 items is included.

Fluorine in Medicinal Chemistry and Chemical Biology

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Publisher : John Wiley & Sons
ISBN 13 : 9780470744086
Total Pages : 640 pages
Book Rating : 4.7/5 (44 download)

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Book Synopsis Fluorine in Medicinal Chemistry and Chemical Biology by : Iwao Ojima

Download or read book Fluorine in Medicinal Chemistry and Chemical Biology written by Iwao Ojima and published by John Wiley & Sons. This book was released on 2009-03-23 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: The extraordinary potential of fluorine-containing molecules in medicinal chemistry and chemical biology has been recognized by researchers outside of the traditional fluorine chemistry field, and thus a new wave of fluorine chemistry is rapidly expanding its biomedical frontiers. With several of the best selling drugs in the world crucially containing fluorine atoms, the incorporation of fluorine to drug leads has become an essential practice in biomedical research, especially for drug design and discovery as well as development. Focusing on the unique and significant roles that fluorine plays in medicinal chemistry and chemical biology, this book reviews recent advances and future prospects in this rapidly developing field. Topics covered include: Discovery and development of fluorine containing drugs and drug candidates. New and efficient synthetic methods for medicinal chemistry and the optimisation of fluorine-containing drug candidates. Structural and chemical biology of fluorinated amino acids and peptides. Fluorine labels as probes in metabolic study, protein engineering and clinical diagnosis. Applications of 19F NMR spectroscopy in biomedical research. An appendix presents an invaluable index of all fluorine-containing drugs that have been approved by the US Food and Drug Administration, including information on structure and pharmaceutical action. Fluorine in Medicinal Chemistry and Chemical Biology will serve as an excellent reference source for graduate students as well as academic and industrial researchers who want to take advantage of fluorine in biomedical research.

Fluorine Chemistry at the Millennium

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Publisher : Elsevier
ISBN 13 : 0080531792
Total Pages : 661 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Fluorine Chemistry at the Millennium by : R.E. Banks

Download or read book Fluorine Chemistry at the Millennium written by R.E. Banks and published by Elsevier. This book was released on 2000-12-04 with total page 661 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume brings together contributions by leading researchers covering a wide scope so characteristic of fluorine chemistry. It is a monograph of historical character comprising personalized accounts of progress and events in areas of particular interest. There is also much to interest and instruct chemists from other disciplines as a good proportion of the chapters contain a considerable amount of 'hard' referenced information relating to modern organic, organoelemental and inorganic chemistry. Historians of chemistry and technology will no doubt be tempted to dip into this book, and surely whoever addresses the task of commemorating Moissan's achievement at the 150-years stage will bless us all in some measure for its existence.

Fluorine in Organic Chemistry

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Author :
Publisher : Blackwell Pub
ISBN 13 : 9781405107877
Total Pages : 406 pages
Book Rating : 4.1/5 (78 download)

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Book Synopsis Fluorine in Organic Chemistry by : Richard D. Chambers

Download or read book Fluorine in Organic Chemistry written by Richard D. Chambers and published by Blackwell Pub. This book was released on 2004 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: The introduction of carbon - fluorine bonds into organic compounds can profoundly influence their chemical and physical properties when compared to their non-fluorine containing analogues, leading to a range of man-made materials with highly desirable properties. These molecules are of interest across the wide spectrum of industrial and academic organic chemistry, from pharmaceuticals, through fine and specialty chemicals to polymers. From Prozac to Teflon, many of the most important products of the chemical and life-science industries rely on organic fluorine chemistry for their useful properties. In this new book the author, internationally known for his contribution to organic fluorine chemistry, covers both the preparative methodologies and chemical properties of partially and highly fluorinated organic systems. Written as an authoritative guide to the subject for organic chemists in universities and the pharmaceutical, agrochemical, specialty organic and polymer industries, the book will also be an important resource for university advanced courses. Dick Chambers is a Fellow of the Royal Society and Emeritus Professor of Chemistry at the University of Durham, Durham, UK.

Concise Handbook of Fluorocarbon Gases

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119323258
Total Pages : 448 pages
Book Rating : 4.1/5 (193 download)

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Book Synopsis Concise Handbook of Fluorocarbon Gases by : Sina Ebnesajjad

Download or read book Concise Handbook of Fluorocarbon Gases written by Sina Ebnesajjad and published by John Wiley & Sons. This book was released on 2021-03-09 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes fluorocarbons gases’ preparation process, properties, applications and their evolution over time. The impact of fluorocarbons on the ozone layer and global and the development to mitigate those effects have been specially emphasized. The first major industrial fluorinated compound was developed in the 1920’s, to replace ammonia and sulfur dioxide refrigerants, at the General Motors Frigidaire Division by Thomas Midgley, Jr. and Albert Leon Henne. They developed a family of fluorocarbons trademarked Freon® for auto air conditioning units revolutionizing the auto industry. Other applications were developed over time including fire extinguishers, propellants, blowing agents, cleaners, anesthesia, artificial blood and others impacting every facet of life. In spite of being in broad global use for nearly a century, fluorocarbon gases have gone through great evolution during the last few decades. In the 1980s it was discovered chlorofluorocarbon (CFC) gases are harmful to the ozone layer, mainly because of their chlorine content. Chlorine was released in the upper atmosphere when chlorofluorocarbon molecules were broken down by the high energy cosmic radiation. CFCs were progressively banned following the Montreal Protocol of 1987. CFCs were replaced by fluorinated gases containing either less chlorine (hydrofluoro-chlorocarbons, or HCFCs), which are much less damaging (about 90% less) to the ozone layer or with fluorinated gases containing no chlorine, i.e. hydrofluorocarbons or HFCs. HFC have no impact on the ozone layer but impact global warming detrimentally. HFCs are usable without need for changes to the existing refrigeration or air conditioning installations. More recently hydrofluoroolefins (HFOs), which have little or no negative impact on global warming, have been developed to replace or reduce the use of HFCs. HFOs are used as single compounds or in blends. Research and development continues to develop and replace the HCFCs and HFCs completely with environmentally friendly products. Concise Handbook of Fluorocarbon Gases presents a reference and text for the commercial fluorocarbon gases which have great many application in a wide range of industries such as refrigeration and air conditioning, as well as consumer products.

Synthetic Aspects of the Fluorination of Organic Compounds

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Author :
Publisher : Taylor & Francis US
ISBN 13 : 9783718651573
Total Pages : 158 pages
Book Rating : 4.6/5 (515 download)

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Book Synopsis Synthetic Aspects of the Fluorination of Organic Compounds by : G. G. Furin

Download or read book Synthetic Aspects of the Fluorination of Organic Compounds written by G. G. Furin and published by Taylor & Francis US. This book was released on 1991 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Organofluorine Compounds

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Publisher : Springer Science & Business Media
ISBN 13 : 3662041642
Total Pages : 281 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Organofluorine Compounds by : Tamejiro Hiyama

Download or read book Organofluorine Compounds written by Tamejiro Hiyama and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: In view of increasing interest in organofluorine compounds, this book was undertaken to describe biological and physical properties of organofluorine compounds, synthetic methods of these, their roles in pharmaceutical, agrochemical and material sciences. In particular, the book will emphasize on the usefulness of fluorination reaction, availability of fluorination agents, so that even graduate students who are unfamiliar to this field can understand and participate in this fascinating heteroatom chemistry.

Handbook of Fluorous Chemistry

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 3527604499
Total Pages : 624 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Handbook of Fluorous Chemistry by : John A. Gladysz

Download or read book Handbook of Fluorous Chemistry written by John A. Gladysz and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited by the leading experts John Gladysz, Dennis Curran, and István Horváth, this handbook is the first to summarize all the essential aspects of this emerging field of chemistry. Whether the reader is seeking an introduction to the concept of fluorous biphase catalysis, summaries of partition coefficients involving fluorous and organic solvents, or information on the latest fluorous mixture separation techniques, this authoritative compilation of contributions, written by the world's top authors, provides key information needed for successfully working with the diverse and fascinating families of fluorous molecules. The large number of reliable experimental procedures in particular makes this the ideal guide for newcomers wanting to use this elegant method in the laboratory. In addition, experts will also find a wealth of important information concisely contained in one ready reference. The result is an indispensable resource for everyone currently working or intending to work in this field.

Preparation, Properties, and Technology of Fluorine and Organic Fluoro Compounds

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Author :
Publisher :
ISBN 13 :
Total Pages : 900 pages
Book Rating : 4.:/5 (4 download)

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Book Synopsis Preparation, Properties, and Technology of Fluorine and Organic Fluoro Compounds by : Charles Slesser

Download or read book Preparation, Properties, and Technology of Fluorine and Organic Fluoro Compounds written by Charles Slesser and published by . This book was released on 1951 with total page 900 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Curious World of Fluorinated Molecules

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Author :
Publisher : Elsevier
ISBN 13 : 0128198753
Total Pages : 456 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis The Curious World of Fluorinated Molecules by : Konrad Seppelt

Download or read book The Curious World of Fluorinated Molecules written by Konrad Seppelt and published by Elsevier. This book was released on 2020-10-30 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Curious World of Fluorinated Molecules: Molecules Containing Fluorine is the sixth volume in the Progress in Fluorine Science series and is edited by the world-renowned scientist Konrad Seppelt. Dr. Seppelt brings together a team of global experts to uncover the multifaceted nature of the most electronegative element in the Periodic Table. The book explores the fascinating world of unpredictable, fluorine-containing molecules through their discoveries, path to recognition, current state of the art, and impact on the broader fields of fluorinated materials development. This volume will inspire and energize researchers, future scientists, and educators working in fluorine chemistry. Highlights the current state of fundamental research of fluorinated molecules that either helped to rewrite the fundamental rules of chemistry or impacted modern material technologies Features contributions from a global team of leading experts in the field Provides a unique combination of the historical and current examples that explain the unique role that fluorine can play in advancing our understanding of the scientific method at large

Synthesis of Novel Fluorine Compounds: New Experimental Challenges in Elemental Fluorine Chemistry

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Author :
Publisher :
ISBN 13 :
Total Pages : 9 pages
Book Rating : 4.:/5 (227 download)

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Book Synopsis Synthesis of Novel Fluorine Compounds: New Experimental Challenges in Elemental Fluorine Chemistry by : Richard J. Lagow

Download or read book Synthesis of Novel Fluorine Compounds: New Experimental Challenges in Elemental Fluorine Chemistry written by Richard J. Lagow and published by . This book was released on 1982 with total page 9 pages. Available in PDF, EPUB and Kindle. Book excerpt: A series of highly branched perfluorocarbon polyethers were prepared and are being characterized. Thermal analysis shows that some of the branched polyethers are stable to about 420 degrees C. The synthetic scheme involves partial direct fluorination with diluted molecular fluorine of a hydrocarbon ester, followed by conversion of the carboxyl groups with sulfur tetrafluoride.