Experimental Approaches To Diabetic Retinopathy

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Experimental Approaches to Diabetic Retinopathy

Author : H.-P. Hammes
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805592752
Total Pages : 241 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Experimental Approaches to Diabetic Retinopathy by : H.-P. Hammes

Download or read book Experimental Approaches to Diabetic Retinopathy written by H.-P. Hammes and published by Karger Medical and Scientific Publishers. This book was released on 2010 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume sets the stage for clinical experts working with diabetic patients as well as for researchers by describing the clinical presentations of retinopathy and their anatomical and functional correlates. It reviews currently available experimental models in animals. The impact of retinal pericytes, neuroglia and, specifically, Mller cells are discussed in detail. The volume addresses a variety of current scientific discussions about mechanisms of damage such as growth factors and the VEGF/PEDF balance in the diabetic eye, the ocular renin-angiotensin system, and leukocyte interactions with the microvasculature among others. Stem and progenitor cells in the retina are discussed as potential directions for future investigation. The final chapters return to emerging clinical aspects, including current approaches to retinopathy as a predictor of cardiovascular risk and how knowledge can be translated from bench to bedside. Bridging a widening gap in medical research between basic scientists, who may lose sight of the clinical presentations, and clinical researchers, who may grow unaware of the limits of experimental models, this volume serves as a reference platform for endocrinologists, diabetologists, ophthalmologists, as well as for scientists involved in clinical and basic research in diabetic retinopathy and other vascular complications of diabetes.

Diabetic Retinopathy

Author : Guei-Sheung Liu
Publisher : Springer Nature
ISBN 13 : 1071632558
Total Pages : 223 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Diabetic Retinopathy by : Guei-Sheung Liu

Download or read book Diabetic Retinopathy written by Guei-Sheung Liu and published by Springer Nature. This book was released on 2023-06-16 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume provides various cellular and experimental animal models and research methodologies to understand the complex interrelated pathophysiological mechanisms triggered by hyperglycemia that underlie the development of diabetic retinopathy. The book covers methods for understanding the pathogenesis of diabetic retinopathy, detection and screening of biomarkers in diabetic retinopathy, as well as novel technologies for diabetic retinopathy management. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Diabetic Retinopathy: Methods and Protocols serves as an invaluable resource for scientists and clinicians who are interested in the area of ophthalmology research.

Clinical Strategies in the Management of Diabetic Retinopathy

Author : Francesco Bandello
Publisher : Springer
ISBN 13 : 3319961578
Total Pages : 300 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Clinical Strategies in the Management of Diabetic Retinopathy by : Francesco Bandello

Download or read book Clinical Strategies in the Management of Diabetic Retinopathy written by Francesco Bandello and published by Springer. This book was released on 2018-09-17 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: The advent of intravitreal treatment with anti-vascular endothelium growth factor (anti-VEGF) antibodies and steroids has revolutionized the management of diabetic retinopathy. This timely 2nd edition delves into therapies involving anti-VEGF, and addresses the complexities inherent in the practical application of these clinical trials, from issues of patient compliance, to consideration of the patient’s overall health status. Clinical Strategies in the Management of Diabetic Retinopathy: Step-by-Step Guide for Ophthalmologists, 2nd Edition covers all the stages of diabetic retinopathy, including clinical manifestations, imaging, and treatment, from the early signs to more advanced levels of severity. Richly-illustrated, this clinical resource is designed to present multiple practical and useful suggestions for the management of each stage of diabetic retinopathy, using algorithms, tables, and summaries. Images of sample cases exemplify the effects of different therapies, including benefits and side effects. Novel perspectives in both imaging and treatment are provided to clearly outline current research in the field, with a look to future directions. Written and edited by well-respected leaders in the field, Clinical Strategies in the Management of Diabetic Retinopathy, 2nd edition is an ideal resource for ophthalmologists aiming to provide optimal clinical management for this sight-threatening disease.

Early Events in Diabetic Retinopathy and Intervention Strategies

Author : Andrew Tsin
Publisher : BoD – Books on Demand
ISBN 13 : 1789230829
Total Pages : 104 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Early Events in Diabetic Retinopathy and Intervention Strategies by : Andrew Tsin

Download or read book Early Events in Diabetic Retinopathy and Intervention Strategies written by Andrew Tsin and published by BoD – Books on Demand. This book was released on 2018-04-18 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of diabetic retinopathy is a long slow process affected by hyperglycemia, hypertension, lipid levels and genetics. It is expected that in 20 years' duration nearly all those with diabetes will exhibit diabetic retinopathy. In some patients, it will progress to blindness. While the number of individuals with diabetes increases, our current treatments are only effective at advanced levels of disease. Further, our screening methods to detect those needing treatment are currently not optimal. Early Events in Diabetic Retinopathy and Intervention Strategies covers topics addressing imaging processes currently available in the development of diabetic retinopathy screening. Potential biomarkers, that may be used to identify those at risk and illuminate the new pathways which lead to diabetic retinopathy, are expounded.

New Mechanisms of Action of Natural Antioxidants in Health and Disease

Author : Silvana Hrelia
Publisher : MDPI
ISBN 13 : 3039362682
Total Pages : 168 pages
Book Rating : 4.0/5 (393 download)

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Book Synopsis New Mechanisms of Action of Natural Antioxidants in Health and Disease by : Silvana Hrelia

Download or read book New Mechanisms of Action of Natural Antioxidants in Health and Disease written by Silvana Hrelia and published by MDPI. This book was released on 2020-07-03 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contributes to increasing the knowledge on the mechanisms of action of natural antioxidants, evidencing their pleiotropic role in the prevention and/or counteraction of degenerative diseases, and promoting their application in the functional food and cosmetic fields.

Diabetic Retinopathy

Author : Gabriele E. Lang
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805582439
Total Pages : 181 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Diabetic Retinopathy by : Gabriele E. Lang

Download or read book Diabetic Retinopathy written by Gabriele E. Lang and published by Karger Medical and Scientific Publishers. This book was released on 2007-01-01 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetic retinopathy (DR), damage of the blood vessels in the retina, is one of the problems that patients may face as a complication of diabetes and is, along with other diabetic eye diseases, the greatest single cause of blindness in developed countries. This publication starts with the description of the mechanisms of development and progression of diabetic macular edema and with the characterization of the early stages of DR. An innovative approach of multimedial mapping methods which enables to differentiate between three DR phenotypes is further described. The standards and novel approaches of laser treatment as well as current surgical options and treatment techniques are discussed. Additional contributions consider the pathology of diffuse macular edema and the implications for surgery, the treatment of DR with triamcinolone and its complications, and the application of somatostatin analogues. A new therapeutic approach is the use of vascular endothelial growth factor inhibitors in diabetic macular edema. The volume concludes with articles on the latest concepts of posterior vitreous detachment by pharmacologic vitreolysis and the specific protein kinase C subtype ß inhibitor ruboxistaurin mesylate. To ophthalmologists and diabetes health care professionals interested in diabetic eye disease this book is an essential up-date.

Prevention of Blindness from Diabetes Mellitus

Author : World Health Organization
Publisher : World Health Organization
ISBN 13 : 924154712X
Total Pages : 49 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Prevention of Blindness from Diabetes Mellitus by : World Health Organization

Download or read book Prevention of Blindness from Diabetes Mellitus written by World Health Organization and published by World Health Organization. This book was released on 2006 with total page 49 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes mellitus is an important public health problem worldwide, and more than 75% of patients who have had diabetes mellitus for more than 20 years will have some sort of retinopathy. Diabetic retinopathy correlates with the duration of diabetes; thus with increasing life expectancy, diabetic retinopathy and the ensuing blindness will tend to increase. In view of the increasing prevalence of diabetes mellitus and diabetic retinopathy throughout most of the world, a consultation on prevention of blindness from diabetes mellitus was convened by the World Health Organization to review the current status of diabetic retinopathy care and to define approaches to screening, early detection and management in populations in different settings. This publication reports on the findings of the consultation and provides recommendations and guidelines for the prevention and care of blindness from diabetes mellitus.

Hypertension and experimental diabetic retinopathy

Author : Nicola Jane Hillman
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (536 download)

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Book Synopsis Hypertension and experimental diabetic retinopathy by : Nicola Jane Hillman

Download or read book Hypertension and experimental diabetic retinopathy written by Nicola Jane Hillman and published by . This book was released on 1997 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Anti-Angiogenic Therapy in Ophthalmology

Author : Andreas Stahl
Publisher : Springer
ISBN 13 : 3319240978
Total Pages : 198 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Anti-Angiogenic Therapy in Ophthalmology by : Andreas Stahl

Download or read book Anti-Angiogenic Therapy in Ophthalmology written by Andreas Stahl and published by Springer. This book was released on 2016-05-13 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a concise overview over the pathology of retinal angiogenic diseases and explains why anti-angiogenic therapy is effective in so many patients. The reader is guided through the various clinical indications for anti-angiogenic therapy and made aware of its merits as well as current challenges and limitations. It is explained how, since its introduction for the treatment of exudative age-related macular degeneration in 2006, anti-angiogenic therapy has revolutionized the way in which we treat a range of ocular diseases. All of the authors are established experts in their respective fields who share their extensive knowledge and clinical experience with the reader. This book is both a valuable introduction to anti-angiogenic therapy in ophthalmology and a day-to-day companion for all ophthalmologists seeing patients with some of the most prevalent retinal diseases.

The Cell Biological Level of Experimental Diabetic Retinopathy

Author : Jihong Lin
Publisher :
ISBN 13 :
Total Pages : 104 pages
Book Rating : 4.:/5 (181 download)

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Book Synopsis The Cell Biological Level of Experimental Diabetic Retinopathy by : Jihong Lin

Download or read book The Cell Biological Level of Experimental Diabetic Retinopathy written by Jihong Lin and published by . This book was released on 2004 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Retinal Pharmacotherapeutics

Author : Q.D. Nguyen
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318055654
Total Pages : 426 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Retinal Pharmacotherapeutics by : Q.D. Nguyen

Download or read book Retinal Pharmacotherapeutics written by Q.D. Nguyen and published by Karger Medical and Scientific Publishers. This book was released on 2015-10-27 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of pharmacotherapeutics in the management of retinal diseases is rapidly evolving, and a favorable therapy for the patient. Today anti-VEGF agents are used for a range of indications from inflammation-related choroidal neovascularization to macular edema secondary to retinal vein occlusion or diabetic retinopathy. Beyond VEGF, there is an array of target areas under investigation – not only for vascular pathologies such as age-related macular degeneration and diabetic eye disease, but also for degenerative, infectious and inflammatory retinal conditions. This publication discusses many aspects from basic research on the retina, to animal models for retinal drug delivery, retinal diseases that are amenable to pharmacotherapy and also drugs and mechanisms in retinal diseases. Anyone concerned with the management of retinal diseases - the general ophthalmologist and the retina specialist alike – will find this book indispensable reading.

Experiments on the Pathogenesis of Diabetic Retinopathy

Author : Paul David Deiter
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (424 download)

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Book Synopsis Experiments on the Pathogenesis of Diabetic Retinopathy by : Paul David Deiter

Download or read book Experiments on the Pathogenesis of Diabetic Retinopathy written by Paul David Deiter and published by . This book was released on 1961 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Fundamentals and Methods of Machine and Deep Learning

Author : Pradeep Singh
Publisher : John Wiley & Sons
ISBN 13 : 1119821886
Total Pages : 480 pages
Book Rating : 4.1/5 (198 download)

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Book Synopsis Fundamentals and Methods of Machine and Deep Learning by : Pradeep Singh

Download or read book Fundamentals and Methods of Machine and Deep Learning written by Pradeep Singh and published by John Wiley & Sons. This book was released on 2022-02-01 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: FUNDAMENTALS AND METHODS OF MACHINE AND DEEP LEARNING The book provides a practical approach by explaining the concepts of machine learning and deep learning algorithms, evaluation of methodology advances, and algorithm demonstrations with applications. Over the past two decades, the field of machine learning and its subfield deep learning have played a main role in software applications development. Also, in recent research studies, they are regarded as one of the disruptive technologies that will transform our future life, business, and the global economy. The recent explosion of digital data in a wide variety of domains, including science, engineering, Internet of Things, biomedical, healthcare, and many business sectors, has declared the era of big data, which cannot be analysed by classical statistics but by the more modern, robust machine learning and deep learning techniques. Since machine learning learns from data rather than by programming hard-coded decision rules, an attempt is being made to use machine learning to make computers that are able to solve problems like human experts in the field. The goal of this book is to present a??practical approach by explaining the concepts of machine learning and deep learning algorithms with applications. Supervised machine learning algorithms, ensemble machine learning algorithms, feature selection, deep learning techniques, and their applications are discussed. Also included in the eighteen chapters is unique information which provides a clear understanding of concepts by using algorithms and case studies illustrated with applications of machine learning and deep learning in different domains, including disease prediction, software defect prediction, online television analysis, medical image processing, etc. Each of the chapters briefly described below provides both a chosen approach and its implementation. Audience Researchers and engineers in artificial intelligence, computer scientists as well as software developers.

Neuroprotective Effects of Phytochemicals in Neurological Disorders

Author : Tahira Farooqui
Publisher : John Wiley & Sons
ISBN 13 : 1119155142
Total Pages : 662 pages
Book Rating : 4.1/5 (191 download)

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Book Synopsis Neuroprotective Effects of Phytochemicals in Neurological Disorders by : Tahira Farooqui

Download or read book Neuroprotective Effects of Phytochemicals in Neurological Disorders written by Tahira Farooqui and published by John Wiley & Sons. This book was released on 2017-03-20 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phytochemicals are naturally occurring bioactive compounds found in edible fruits, plants, vegetables, and herbs. Unlike vitamins and minerals, phytochemicals are not needed for the maintenance of cell viability, but they play a vital role in protecting neural cells from inflammation and oxidative stress associated with normal aging and acute and chronic age-related brain diseases. Neuroprotective Effects of Phytochemicals in Neurological Disorders explores the advances in our understanding of the potential neuroprotective benefits that these naturally occurring chemicals contain. Neuroprotective Effects of Phytochemicals in Neurological Disorders explores the role that a number of plant-based chemical compounds play in a wide variety of neurological disorders. Chapters explore the impact of phytochemicals on neurotraumatic disorders, such as stroke and spinal cord injury, alongside neurodegenerative diseases such as Alzheimer's and Parkinson's Disease, as well as neuropsychiatric disorders such as depression and schizophrenia. The chapters and sections of this book provide the reader with a big picture view of this field of research. Neuroprotective Effects of Phytochemicals in Neurological Disorders aims to present readers with a comprehensive and cutting edge look at the effects of phytochemicals on the brain and neurological disorders in a manner useful to researchers, neuroscientists, clinical nutritionists, and physicians.

Vitreoretinal Surgery

Author : Thomas H. Williamson
Publisher : Springer Science & Business Media
ISBN 13 : 364231872X
Total Pages : 435 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Vitreoretinal Surgery by : Thomas H. Williamson

Download or read book Vitreoretinal Surgery written by Thomas H. Williamson and published by Springer Science & Business Media. This book was released on 2013-05-22 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second edition of a highly successful textbook that in many areas has become the preferred manual of vitreoretinal surgery. It provides a complete guide to all common vitreoretinal surgical procedures and also covers diagnosis and other aspects of management. The book is designed to allow a trainee or professional vitreoretinal surgeon to determine the best methodology in individual cases. In order to acquaint the reader with different opinions, “surgical pearls” have been contributed by other international experts in the field. These have proved popular in the past as an illustration of alternative methods, without detracting from the overall method described by the main author. Vitreoretinal Surgery will continue to prove particularly popular amongst trainees, but will also be of value to practicing professionals who need help in the management of difficult and rare cases. The text is backed up by the provision of videos of some aspects of the surgery.

Neurodegeneration and Inflammation

Author : Olga Simó Servat
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (115 download)

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Book Synopsis Neurodegeneration and Inflammation by : Olga Simó Servat

Download or read book Neurodegeneration and Inflammation written by Olga Simó Servat and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Diabetic Renal-Retinal Syndrome

Author : E.A. Friedman
Publisher : Springer Science & Business Media
ISBN 13 : 9401006148
Total Pages : 272 pages
Book Rating : 4.4/5 (1 download)

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Book Synopsis Diabetic Renal-Retinal Syndrome by : E.A. Friedman

Download or read book Diabetic Renal-Retinal Syndrome written by E.A. Friedman and published by Springer Science & Business Media. This book was released on 2011-06-27 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fresh insights into the pathogenic mechanisms by which hyperglycemia induces tissue and organ injurt are the basis for rapidly evolving promising therapies in diabetes. Especially promising as targets for intervention are products of oxidative stress, including kinins and growth factors. Improving results of renal replacement regimes now incorporating pancreatic islet transplants are able to delay and prevent end-organ damage in diabetic individuals. The evolving story of the taming of diabetes is of direct concern to nephrologists, endocrinologists, ophthalmologists, primary care physicians and medical students.