Experimental Approaches to Biopharmaceutics and Pharmacokinetics

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Author :
Publisher : Pharmamed Press
ISBN 13 : 9789389974744
Total Pages : 164 pages
Book Rating : 4.9/5 (747 download)

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Book Synopsis Experimental Approaches to Biopharmaceutics and Pharmacokinetics by : Suresh Bandari

Download or read book Experimental Approaches to Biopharmaceutics and Pharmacokinetics written by Suresh Bandari and published by Pharmamed Press. This book was released on 2017-08-27 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to equip pharmacy graduate and post graduate students with the knowledge and skills required to conduct various experiments relevant to biopharmaceutics and pharmacokinetics. The focus is on providing information about how biopharmaceutical experiments are conducted and how pharmacokinetic parameters are determined.

Biopharmaceutics and Pharmacokinetics

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Author :
Publisher : Lavoisier
ISBN 13 :
Total Pages : 635 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Biopharmaceutics and Pharmacokinetics by : Jean M. Aiache

Download or read book Biopharmaceutics and Pharmacokinetics written by Jean M. Aiache and published by Lavoisier. This book was released on 1984 with total page 635 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Computational and Experimental Approaches in Multi-Target Pharmacology

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (136 download)

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Book Synopsis Computational and Experimental Approaches in Multi-Target Pharmacology by :

Download or read book Computational and Experimental Approaches in Multi-Target Pharmacology written by and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The next frontier in pharmacology is the development of multi-target strategies in which pathological processes are controlled by pharmacologically manipulating them at many different points at once. Designing multi-target strategies will require deep understanding of the complex physiology that underlies pathological processes. It will also require the development of single drugs with multiple targets, or combinations of drugs with compatible pharmacokinetics that work synergistically to maximize desirable effects while minimizing unwanted side effects. This e-Book contains ten original articles, each addressing a different aspect of this challenge. Together they open new perspectives and show the way forward in the development of multi-target therapeutics.

Third European Congress of Biopharmaceutics and Pharmacokinetics

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Publisher :
ISBN 13 : 9782876630024
Total Pages : 680 pages
Book Rating : 4.6/5 (3 download)

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Book Synopsis Third European Congress of Biopharmaceutics and Pharmacokinetics by : Jean M. Aiache

Download or read book Third European Congress of Biopharmaceutics and Pharmacokinetics written by Jean M. Aiache and published by . This book was released on 1987 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biopharmaceutics and Pharmacokinetics Considerations

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Publisher : Academic Press
ISBN 13 : 0128144262
Total Pages : 754 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Biopharmaceutics and Pharmacokinetics Considerations by :

Download or read book Biopharmaceutics and Pharmacokinetics Considerations written by and published by Academic Press. This book was released on 2021-07-07 with total page 754 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biopharmaceutics and Pharmacokinetics Considerations examines the history of biopharmaceutics and pharmacokinetics. The book provides a biopharmaceutics and pharmacokinetics approach to addressing issues in formulation development and ethical considerations in handling animals. Written by experts in the field, this volume within the Advances in Pharmaceutical Product Development and Research series deepens understanding of biopharmaceutics and pharmacokinetics within drug discovery and drug development. Each chapter delves into a particular aspect of this fundamental field to cover the principles, methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to study the chemical and physical properties of drugs and the biological effects they produce. Examines the most recent developments in biopharmaceutics and pharmacokinetics for pharmaceutical sciences Covers the principles, methodologies and technologies of biopharmaceutics and pharmacokinetics Focuses on the pharmaceutical sciences, but also encompasses aspects of toxicology, neuroscience, environmental sciences and nanotechnology

Modeling in Biopharmaceutics, Pharmacokinetics and Pharmacodynamics

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Publisher : Springer
ISBN 13 : 9783319275963
Total Pages : 0 pages
Book Rating : 4.2/5 (759 download)

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Book Synopsis Modeling in Biopharmaceutics, Pharmacokinetics and Pharmacodynamics by : Panos Macheras

Download or read book Modeling in Biopharmaceutics, Pharmacokinetics and Pharmacodynamics written by Panos Macheras and published by Springer. This book was released on 2016-04-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this new second edition book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. The book is divided into four parts; the first deals with the fundamental principles of fractals, diffusion and nonlinear dynamics; the second with drug dissolution, release, and absorption; the third with epirical, compartmental, and stochastic pharmacokinetic models, with two new chapters, one on fractional pharmacokinetics and one on bioequivalence; and the fourth mainly with classical and nonclassical aspects of pharmacodynamics. The classical models that have relevance and application to these sciences are also considered throughout. This second edition has new information on reaction limited models of dissolution, non binary biopharmaceutic classification system, time varying models, and interface models. Many examples are used to illustrate the intrinsic complexity of drug administration related phenomena in the human, justifying the use of advanced modeling methods. This book will appeal to graduate students and researchers in pharmacology, pharmaceutical sciences, bioengineering, and physiology. Reviews of the first edition: "This book presents a novel modelling approach to biopharmaceutics, pharmacokinetics and pharmacodynamic phenomena. This state-of-the-art volume will be helpful to students and researchers in pharmacology, bioengineering, and physiology. This book is a must for pharmaceutical researchers to keep up with recent developments in this field." (P. R. Parthasarathy, Zentralblatt MATH, Vol. 1103 (5), 2007) "These authors are the unique (or sole) contributors in this area that are working on these questions and bring a special expertise to the field that is now being recognized as essential to understanding biological system and kinetic/dynamic characteristics in drug development...This text is an essential primer for those who would envision the incorporation of heterogeneous approaches to systems where homogeneous approaches are not sufficient to describe the system." (Robert R. Bies, Journal of Clinical Pharmacology, Vol. 46, 2006)

Proceedings

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Publisher :
ISBN 13 :
Total Pages : 635 pages
Book Rating : 4.:/5 (722 download)

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Book Synopsis Proceedings by :

Download or read book Proceedings written by and published by . This book was released on 1984 with total page 635 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Second European Congress of Biopharmaceutics and Pharmacokinetics: Experimental pharmacokinetics

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Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (354 download)

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Book Synopsis Second European Congress of Biopharmaceutics and Pharmacokinetics: Experimental pharmacokinetics by : Jean M. Aiache

Download or read book Second European Congress of Biopharmaceutics and Pharmacokinetics: Experimental pharmacokinetics written by Jean M. Aiache and published by . This book was released on 1984 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pharmacokinetics and Pharmacodynamics of Biotech Drugs

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Publisher : John Wiley & Sons
ISBN 13 : 3527609520
Total Pages : 426 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Pharmacokinetics and Pharmacodynamics of Biotech Drugs by : Bernd Meibohm

Download or read book Pharmacokinetics and Pharmacodynamics of Biotech Drugs written by Bernd Meibohm and published by John Wiley & Sons. This book was released on 2006-12-13 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first ever coverage of the pharmacokinetic and pharmacodynamic characteristics of biopharmaceuticals meets the need for a comprehensive book in this field. It spans all topics from lead identification right up to final-stage clinical trials. Following an introduction to the role of PK and PD in the development of biotech drugs, the book goes on to cover the basics, including the pharmacokinetics of peptides, monoclonal antibodies, antisense oligonucleotides, as well as viral and non-viral gene delivery vectors. The second section discusses such challenges and opportunities as pulmonary delivery of proteins and peptides, and the delivery of oligonucleotides. The final section considers the integration of PK and PD concepts into the biotech drug development plan, taking as case studies the preclinical and clinical drug development of tasidotin, as well as the examples of cetuximab and pegfilgrastim. The result is vital reading for all pharmaceutical researchers.

Pharmacokinetics: Basics to Applications

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Publisher : Springer Nature
ISBN 13 : 9811689504
Total Pages : 354 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Pharmacokinetics: Basics to Applications by : Biswajit Mukherjee

Download or read book Pharmacokinetics: Basics to Applications written by Biswajit Mukherjee and published by Springer Nature. This book was released on 2022-03-17 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook covers all the essential elements of pharmacokinetics, from basics to applications. It describes authoritative equations and methods on pharmacokinetic evaluation procedures with their importance. Each chapter of the book is supplemented with numerous illustrations and figures for easy understanding of the subject. The book presents mathematical techniques, step- by-step descriptive equations, and applicable statistical analysis methods for the easy understanding of the topic. Further, it covers the preclinical applications and methods of pharmacokinetic aspects. The book also contains mathematical problems and questions related to pharmacokinetics for students. Special emphasis is on recent pharmacokinetic methods and their applications for managing clinical data and biostatistical approaches based on the current literature. This book is primarily meant for researchers and students from academic institutions and to R&D professionals.

In Vitro-In Vivo Correlations

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Publisher : Springer Science & Business Media
ISBN 13 : 1468460366
Total Pages : 299 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis In Vitro-In Vivo Correlations by : David B. Young

Download or read book In Vitro-In Vivo Correlations written by David B. Young and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents the invited presentations and some of the posters presented at the conference entitled "In Vitro-In Vivo Relationship (IVIVR) Workshop" held in Sep tember, 1996. The workshop was organized by the IVIVR Cooperative Working Group which has drawn together scientists from a number of organizations and institutions, both academic and industrial. In addition to Elan Corporation, which is a drug delivery com pany specializing in the development of ER (Extended Release) dosage forms, the IVIVR Cooperative Working Group consists of collaborators from the University of Maryland at Baltimore, University College Dublin, Trinity College Dublin, and the University of Not tingham in the UK. The principal collaborators are: Dr. Jackie Butler, Elan Corporation Prof. Owen Corrigan, Trinity College Dublin Dr. lain Cumming, Elan Corporation Dr. John Devane, Elan Corporation Dr. Adrian Dunne, University College Dublin Dr. Stuart Madden, Elan Corporation Dr. Colin Melia, University of Nottingham Mr. Tom O'Hara, Elan Corporation Dr. Deborah Piscitelli, University of Maryland at Baltimore Dr. Araz Raoof, Elan Corporation Mr. Paul Stark, Elan Corporation Dr. David Young, University of Maryland at Baltimore The purpose of the workshop was to discuss new concepts and methods in the devel opment of in vitro-in vivo relationships for ER products. The original idea went back ap proximately 15 months prior to the workshop itself. For some time, the principal collaborators had been working together on various aspects of dosage form development.

Pharmaceutical Biotechnology

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Publisher : John Wiley & Sons
ISBN 13 : 111868575X
Total Pages : 499 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Pharmaceutical Biotechnology by : Gary Walsh

Download or read book Pharmaceutical Biotechnology written by Gary Walsh and published by John Wiley & Sons. This book was released on 2013-04-25 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmaceutical Biotechnology offers students taking Pharmacy and related Medical and Pharmaceutical courses a comprehensive introduction to the fast-moving area of biopharmaceuticals. With a particular focus on the subject taken from a pharmaceutical perspective, initial chapters offer a broad introduction to protein science and recombinant DNA technology- key areas that underpin the whole subject. Subsequent chapters focus upon the development, production and analysis of these substances. Finally the book moves on to explore the science, biotechnology and medical applications of specific biotech products categories. These include not only protein-based substances but also nucleic acid and cell-based products. introduces essential principles underlining modern biotechnology- recombinant DNA technology and protein science an invaluable introduction to this fast-moving subject aimed specifically at pharmacy and medical students includes specific ‘product category chapters’ focusing on the pharmaceutical, medical and therapeutic properties of numerous biopharmaceutical products. entire chapter devoted to the principles of genetic engineering and how these drugs are developed. includes numerous relevant case studies to enhance student understanding no prior knowledge of protein structure is assumed

Biopharmaceutics Applications in Drug Development

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Publisher : Springer Science & Business Media
ISBN 13 : 038772379X
Total Pages : 416 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Biopharmaceutics Applications in Drug Development by : Rajesh Krishna

Download or read book Biopharmaceutics Applications in Drug Development written by Rajesh Krishna and published by Springer Science & Business Media. This book was released on 2007-09-20 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: The highly experienced authors here present readers with step-wise, detail-conscious information to develop quality pharmaceuticals. The book is made up of carefully crafted sections introducing key concepts and advances in the areas of dissolution, BA/BE, BCS, IVIC, and product quality. It provides a specific focus on the integration of regulatory considerations and includes case histories highlighting the biopharmaceutics strategies adopted in development of successful drugs.

The Art and Science of Physiologically-Based Pharmacokinetics Modeling

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Publisher : CRC Press
ISBN 13 : 1040033121
Total Pages : 357 pages
Book Rating : 4.0/5 (4 download)

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Book Synopsis The Art and Science of Physiologically-Based Pharmacokinetics Modeling by : Rodrigo Cristofoletti

Download or read book The Art and Science of Physiologically-Based Pharmacokinetics Modeling written by Rodrigo Cristofoletti and published by CRC Press. This book was released on 2024-07-15 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: This state-of-the-art text describes the science behind the system and drug-dependent components of PBPK models, its applications in translational and regulatory science, e.g., guiding drug discovery and development, and supporting precision medicine initiatives. To incorporate state-of-the-art knowledge, each chapter is written by leaders in the field and illustrated by clear case studies. Connecting basic and applied science, this book explores the potential of PBPK modeling for improving therapeutics and is designed for a wide audience encompassing graduate students as well as biopharmaceutics scientists and clinical pharmacologists. Features: 1. Provides a basic understanding of the physiologically-based pharmacokinetic modeling and its applications 2. Assists the reader in understanding product performance to allow for rapid product development and establish bioequivalence 3. Well-constructed content and added value of real examples 4. Illustrates how using available resources via modeling and simulation leads to a reduction in the costs related to drug development, which directly affects the costs to patients

Applied Biopharmaceutics & Pharmacokinetics

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Publisher : McGraw-Hill/Appleton & Lange
ISBN 13 :
Total Pages : 800 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Applied Biopharmaceutics & Pharmacokinetics by : Leon Shargel

Download or read book Applied Biopharmaceutics & Pharmacokinetics written by Leon Shargel and published by McGraw-Hill/Appleton & Lange. This book was released on 1999 with total page 800 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work emphasizes the application and understanding of core areas involving bioavailability, population pharmacokinetics, pharmacodynamics, metabolism and drug delivery.

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Author :
Publisher : Pharma Career Publications
ISBN 13 :
Total Pages : 159 pages
Book Rating : 4./5 ( download)

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Book Synopsis by :

Download or read book written by and published by Pharma Career Publications. This book was released on with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Shargel and Yu's Applied Biopharmaceutics & Pharmacokinetics, 8th Edition

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Author :
Publisher : McGraw Hill Professional
ISBN 13 : 1260143007
Total Pages : 1035 pages
Book Rating : 4.2/5 (61 download)

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Book Synopsis Shargel and Yu's Applied Biopharmaceutics & Pharmacokinetics, 8th Edition by : Leon Shargel

Download or read book Shargel and Yu's Applied Biopharmaceutics & Pharmacokinetics, 8th Edition written by Leon Shargel and published by McGraw Hill Professional. This book was released on 2022-01-24 with total page 1035 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authoritative textbook on the principles and practical applications of biopharmaceutics and pharmacokinetics Shargel & Yu's Applied Biopharmaceutics & Pharmacokinetics has been the standard textbook in its field for over 40 years. This eighth edition includes recent scientific developments in the field and embodies the collective contribution of experts with deep knowledge and experience in the selected subject areas. Shargel & Yu's Applied Biopharmaceutics & Pharmacokinetics, Eighth Edition provides the reader with a fundamental understanding of biopharmaceutics and pharmacokinetics principles that can be applied to patient drug therapy and rational drug product development. Shargel & Yu's Applied Biopharmaceutics & Pharmacokinetics, Eighth Edition has been expanded and revised to include advancements in biopharmaceutics and pharmacokinetics. The chapter sequence has been reorganized into four main sections, providing a more logical sequence for students. The textbook starts with fundamental concepts, followed by application of these principles to optimize drug therapy and to the rational development of drug products. Each chapter includes theoretical concepts with practical examples and clinical applications. Frequently asked questions provide a discussion of overall concepts. Features: Expanded and revised chapters to include scientific advances in biopharmaceutics and pharmacokinetics Four main sections providing a natural buildup of knowledge: introduction to biopharmaceutics and pharmacokinetics, fundamentals of biopharmaceutics, pharmacokinetic calculations, clinical pharmacokinetics and pharmacodynamics, and biopharmaceutics and pharmacokinetics in drug product development Additional chapters for this edition include: o Physiological factors related to drug absorption o Approaches to pharmacokinetics and pharmacodynamics calculations o Novel and complex dosage Forms o Clinical Development and Therapeutic Equivalence of Generic Drug and Biosimilar Products o Pharmacokinetics and Pharmacodynamics in Clinical Drug Product Development Additional information on drug therapy, drug product performance, and other related topics Frequently asked questions, practice problems, clinical examples and learning questions