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Expanding Applications Of Iron Oxide Nanoparticles By Surface Functionalization
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Book Synopsis Expanding Applications of Iron Oxide Nanoparticles by Surface Functionalization by : Chuansong Duanmu
Download or read book Expanding Applications of Iron Oxide Nanoparticles by Surface Functionalization written by Chuansong Duanmu and published by . This book was released on 2009 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this dissertation, research efforts mainly focused on exploring the applications of superparamagnetic iron oxide nanoparticles (SPIONs) in MR imaging and nanocatalysis via surface functionalization.
Book Synopsis Synthesis and Surface Functionalization of Iron Oxide Nanoparticles Towards Radiolabelling for the Application in Molecular Imaging by : Aladdin Hussein
Download or read book Synthesis and Surface Functionalization of Iron Oxide Nanoparticles Towards Radiolabelling for the Application in Molecular Imaging written by Aladdin Hussein and published by . This book was released on 2012 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Iron Oxide Nanoparticles for Biomedical Applications by : Sophie Laurent
Download or read book Iron Oxide Nanoparticles for Biomedical Applications written by Sophie Laurent and published by Elsevier. This book was released on 2017-10-20 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Iron Oxide Nanoparticles for Biomedical Applications: Synthesis, Functionalization and Application begins with several chapters covering the synthesis, stabilization, physico-chemical characterization and functionalization of iron oxide nanoparticles. The second part of the book outlines the various biomedical imaging applications that currently take advantage of the magnetic properties of iron oxide nanoparticles. Brief attention is given to potential iron oxide based therapies, while the final chapter covers nanocytotoxicity, which is a key concern wherever exposure to nanomaterials might occur. This comprehensive book is an essential reference for all those academics and professionals who require thorough knowledge of recent and future developments in the role of iron oxide nanoparticles in biomedicine. Unlocks the potential of iron oxide nanoparticles to transform diagnostic imaging techniques Contains full coverage of new developments and recent research, making this essential reading for researchers and engineers alike Explains the synthesis, processing and characterization of iron oxide nanoparticles with a view to their use in biomedicine
Book Synopsis Synthesis, Surface Functionalization, and Biological Testing of Iron Oxide Nanoparticles for Development as a Cancer Therapeutic by : Stanley Eugene Gilliland (III)
Download or read book Synthesis, Surface Functionalization, and Biological Testing of Iron Oxide Nanoparticles for Development as a Cancer Therapeutic written by Stanley Eugene Gilliland (III) and published by . This book was released on 2015 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Iron oxide nanoparticles are highly researched for their use in biomedical applications such as drug delivery, diagnosis, and therapy. The inherent biodegradable and biocompatible nanoparticle properties make them highly advantageous in nanomedicine. The magnetic properties of iron oxide nanoparticles make them promising candidates for magnetic fluid hyperthermia applications. Designing an efficient iron oxide nanoparticle for hyperthermia requires synthetic, surface functionalization, stability, and biological investigations. This research focused on the following three areas: optimizing synthesis conditions for maximum radiofrequency induced magnetic hyperthermia, designing a simple and modifiable surface functionalization method for specific or broad biological stability, and in vitro and in vivo testing of surface functionalized iron oxide nanoparticles in delivering effective hyperthermia or radiotherapy. The benzyl alcohol modified seed growth method of synthesizing iron oxide nanoparticles using iron acetylacetonate as an iron precursor was investigated to identify significant nanoparticle properties that effect radiofrequency induced magnetic hyperthermia. Investigation of this synthesis under atmospheric conditions revealed a combination of thermal decomposition and oxidation-reduction mechanisms that can produce nanoparticles with larger crystallite sizes and decreased size distributions. Nanoparticles were easily surface functionalized with (3-Glycidyloxypropyl)trimethoxysilane (GLYMO) without the need for organic-aqueous phase transfer methods. The epoxy ring on GLYMO facilitated post-modifications via a base catalyzed epoxy ring opening to obtain nanoparticles with different terminal groups. Glycine, serine, [gamma]-aminobutryic acid (ABA), (S)-( - )-4-amino-2-hydroxybutyric acid (SAHBA), ethylenediamine, and tetraethylenepentamine were successful in modifying GLYMO coated-iron oxide nanoparticles to provide colloidal and varying biological stability while also allowing for further conjugation of chemotherapeutics or radiotherapeutics. The colloidal stability of cationic and anionic nanoparticles in several biologically relevant media was studied to address claims of increased cellular uptake for cationic nanoparticles. The surface functionalized iron oxide nanoparticles were investigated to determine effects on cellular uptake and viability. In vitro tests were used to confirm the ability of iron oxide nanoparticles to provide effective hyperthermia treatment. S-2-(4-Aminobenzyl)-1,4,7,10-tetraazacyclododecane tetraacetic acid (DOTA) was coupled to SAHBA and carboxymethylated polyvinyl alcohol surface functionalized iron oxide nanoparticles and radiolabeled with 177Lu. The capability of radiolabeled iron oxide nanoparticles for delivering radiation therapy to a U87MG murine orthotopic xenograft model of glioblastoma was initially investigated.
Book Synopsis Functionalization of Iron Oxide Nanoparticles and the Impact on Surface Reactive Oxygen Species Generation for Potential Biomedical and Environmental Applications by : Trang Thi Thu Mai
Download or read book Functionalization of Iron Oxide Nanoparticles and the Impact on Surface Reactive Oxygen Species Generation for Potential Biomedical and Environmental Applications written by Trang Thi Thu Mai and published by . This book was released on 2019 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Green Nanochemistry written by and published by . This book was released on 2012 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Iron Oxide Nanoparticles for Biomedical Applications by : Sophie Laurent
Download or read book Iron Oxide Nanoparticles for Biomedical Applications written by Sophie Laurent and published by Elsevier. This book was released on 2017-10-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Iron Oxide Nanoparticles for Biomedical Applications: Synthesis, Functionalization and Application begins with several chapters covering the synthesis, stabilization, physico-chemical characterization and functionalization of iron oxide nanoparticles. The second part of the book outlines the various biomedical imaging applications that currently take advantage of the magnetic properties of iron oxide nanoparticles. Brief attention is given to potential iron oxide based therapies, while the final chapter covers nanocytotoxicity, which is a key concern wherever exposure to nanomaterials might occur. This comprehensive book is an essential reference for all those academics and professionals who require thorough knowledge of recent and future developments in the role of iron oxide nanoparticles in biomedicine.
Book Synopsis Functionalization of Iron Oxide Nanoparticles for Bio Applications by : Fereshta Hafizi
Download or read book Functionalization of Iron Oxide Nanoparticles for Bio Applications written by Fereshta Hafizi and published by . This book was released on 2021 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Iron Oxide Nanoparticle Surface Modification by : Richard Hoff
Download or read book Iron Oxide Nanoparticle Surface Modification written by Richard Hoff and published by . This book was released on 2019 with total page 65 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multifunctional nanomaterials can be engineered to aid in the diagnosis of diseases, enable efficient drug delivery, monitor treatment progress over time, and evaluate treatment outcomes. This strategy, known as theranostics, focuses on the combination of diagnostic and therapeutic techniques to provide new clinically safe and efficient personalized treatments. The evaluation of different nanomaterials' properties and their customization for specific medical applications has therefore been a significant area of interest within the scientific community. Iron oxide nanoparticles, specifically those based on iron (II, III) oxide (magnetite, Fe3O4), have been prominently investigated for biomedical, theranostic applications due to their documented superparamagnetism, high biocompatibility, and other unique physicochemical properties. The aim of this thesis is to establish a viable set of methods for preparing magnetite (iron oxide) nanoparticles through hydrothermal synthesis and modifying their surfaces with organic functional groups in order to both modulate surface chemistry and facilitate the attachment of molecules such as peptides via covalent bond formations. Modifying their surfaces with biomolecules such as peptides can further increase their uptake into cells, which is a necessary step in the mechanisms of their desired biomedical applications. The methods of nanoparticle synthesis, surface functionalization, and characterization involving electron microscopy (e.g., SEM, TEM), zeta potential measurements, size analysis (i.e., DLS), and FT-IR spectroscopy will be presented.
Book Synopsis Iron Oxide Nanoparticles and Their Applications by : Patricia Villegas
Download or read book Iron Oxide Nanoparticles and Their Applications written by Patricia Villegas and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Iron oxide nanoparticles demonstrate a number of unique properties, including superparamagnetism, biocompatibility, and non-toxicity, which make them an ideal candidate for a variety of applications, as described in this book. Chapter One deals with the recent advances in various synthetic procedures of iron oxide-based nanocomposites, their characterization methods, and their potential applications in energy storage devices, supercapacitors, fuel cells, and more. Chapter Two summarizes current applications of immobilized enzymes based on iron oxide magnetic nanoparticles and discusses future growth prospects. Chapter Three reviews the properties and applications of enzymatic sensors in exploiting tyrosinase, glucose oxidase, and other enzymes for sensing a broad range of biomedical species. Chapter Four discusses magnetic magnetite and maghemite iron oxide nanoparticles from a variety of perspectives. Chapter Five describes how nano iron oxides could be used to remove pollutants from the environment. Chapter Six provides a comprehensive review of the catalytic applications of iron oxide nanoparticles in organic synthesis, high temperature reactions, gas-phase processes, wastewater treatment and supercritical upgradation of heavy petroleum oils. Chapter Seven details the photocatalytic degradation of a class of toxic, aromatic pollutants, namely, phenols and substituted phenols using different types of photocatalysts in the nano size range for effective removal these compounds from water bodies. Lastly, Chapter Eight elucidates various magnetic nanomaterials-based adsorbents used in adsorption techniques for wastewater treatment.
Book Synopsis Functionalization of Silica-coated Iron Oxide Nanoparticles Via the Silanol-alcohol Condensation Reaction by : Henry J. H Kang
Download or read book Functionalization of Silica-coated Iron Oxide Nanoparticles Via the Silanol-alcohol Condensation Reaction written by Henry J. H Kang and published by . This book was released on 2019 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: The surface properties of nanoparticles play an important role in their interactions with their surroundings. Silane reagents have been used for surface modifications to silica shells on iron oxide nanoparticles, but using these reagents presents some challenges. Some of these challenges include the moisture sensitivity of silane reagents and the formation of multilayers. An alternative approach to modifying the surfaces of these silica shells was developed to impart different terminal functional groups, such as a thiol, alcohol, or carboxylic acid, through the use of alcohol-based reagents. This reaction was initiated through convective heating and microwave-assisted heating. This approach to surface functionalization of the core-shell particles was verified through analytical measurements and the attachment of gold nanoparticles. The silanol-alcohol condensation reaction was also extended to the mixed functionalization of the silica-coated iron oxide nanoparticles with both thiol and carboxylic acid functionalized alcohol reagents. The processes and results for the silanol-alcohol condensation reaction were also compared with silanization process. The use of the silanol-alcohol condensation reaction could be extended further to other surface functionalization through the use of additional alcohol-based reagents.
Book Synopsis Synthesis and Functionalization of Iron Oxide Nanoparticles and Their Application in Hybrid Materials by : Phillip Georg Daniel
Download or read book Synthesis and Functionalization of Iron Oxide Nanoparticles and Their Application in Hybrid Materials written by Phillip Georg Daniel and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Iron Oxide-Based Nanocomposites and Nanoenzymes by : Harekrushna Sahoo
Download or read book Iron Oxide-Based Nanocomposites and Nanoenzymes written by Harekrushna Sahoo and published by Springer Nature. This book was released on 2024-01-01 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: This contributed volume provides a comprehensive understanding of synthetic protocols, characterization techniques, and current applications of iron oxide-based nanocomposite and nanoenzyme materials. It covers basic concepts and recent advancements in iron oxide-based nanocomposites and nanoenzymes, focusing on their synthesis, characterization, and functionalization for specific research applications. The different chapters in the book highlight key characterization techniques including Fourier Transform Infrared Spectroscopy, X-ray diffraction, Scanning Electron Microscopy, and Transmission Electron Microscopy, among others while it also explores various applications of these materials, such as adsorption of heavy metals and dyes, gas sensors, biomedical applications, photo-catalysis, and photovoltaic sensors. This book serves as a valuable resource for researchers and graduate students working in the fields of materials science, chemistry, physics, and biotechnology.
Book Synopsis Characterization and Functionalization of Iron-oxide Nanoparticles for Use as Potential Agents for Cancer Thermotherapy by :
Download or read book Characterization and Functionalization of Iron-oxide Nanoparticles for Use as Potential Agents for Cancer Thermotherapy written by and published by . This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis presents experimental studies of iron oxide nanoparticle synthesis, functionalization, and intracellular hyperthermal effects on murine macrophages as a model in vitro system. Colloidal suspensions of magnetic nanoparticles (MNPs) are of particular interest in Magnetic Fluid Hyperthermia (MFH). Iron oxide nanoparticles (IONPs) have garnered great interest as economical, biocompatible hyperthermia agents due to their superparamagnetic activity. Here we seek to optimize the synthetic reproducibility and in vitro utilization of IONPs for application in MFH. We compared aqueous synthetic protocols and various protective coating techniques using various analytical techniques and in vitro assays to assess the biocompatibility and feasibility of the various preparations of nanoparticles. Using a co-precipitation of iron salts methodology, iron oxide nanoparticles (IONPs) with an average diameter of 6-8nm were synthesized and stabilized with carboxylates. By performing calorimetry measurements in an oscillating magnetic field (OMF) with a frequency of 500 kHz and field strength of 0.008Tesla the superparamagnetic behavior of these particles was confirmed. To further investigate these IONPs in a biological application, citric acid-stabilized particles, in conjunction with heat generated by these IONPs when exposed to an OMF, were assessed to determine their effects on cell viability in a RAW 267.4 murine macrophage model system. Our results show that 91.5-97% of cells that have ingested IONPs die follow exposure to an OMF. Importantly, neither the IONPs (at applicable concentrations) nor the OMF show cytotoxic effects. These particular particles have promising preliminary results as hyperthermic agents in both the current literature and simple, proof-of-concept experiments in our laboratory setting. We present experimental results for the synthesis, characterization, and utilization of iron oxide nanoparticles in MFH. Our results show that while IONPs have potential in MFH, efforts to advance IONPs from laboratory to clinical contexts, where reliable generative techniques and consistent performance properties are necessary, will require an understanding of the influence of the diverse intrinsic structural and magnetic characteristics as well as surface chemistry of nanoparticles, as well as the mechanisms of particle uptake and cell death due to intracellular hyperthermia.
Book Synopsis Superparamagnetic Iron Oxide Nanoparticles by : Morteza Mahmoudi
Download or read book Superparamagnetic Iron Oxide Nanoparticles written by Morteza Mahmoudi and published by . This book was released on 2010-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the fabrication of nanoparticles and exploration of their properties have attracted the attention of physicists, chemists, biologists and engineers. Interest in nanoparticles arise from the fact that the mechanical, chemical, electrical, optical, magnetic, electro-optical and magneto-optical properties of these particles are different from their bulk properties and depend on the particle size. There are numerous areas where nanoparticulate systems are of scientific and technological interest. This book reviews research on the various components of superparamagnetic iron oxide nanoparticles.
Book Synopsis Surface Functionalized Iron Oxide Nanoparticles for Applications in Biomedical Sciences by : Joel Kuhn
Download or read book Surface Functionalized Iron Oxide Nanoparticles for Applications in Biomedical Sciences written by Joel Kuhn and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Superparamagnetic Iron Oxide Nanoparticles by : Morteza Mahmoudi
Download or read book Superparamagnetic Iron Oxide Nanoparticles written by Morteza Mahmoudi and published by . This book was released on 2011 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt:
