Excitation Contraction Coupling In Smooth Muscle

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Smooth Muscle Excitation

Author : T. B. Bolton
Publisher :
ISBN 13 :
Total Pages : 568 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Smooth Muscle Excitation by : T. B. Bolton

Download or read book Smooth Muscle Excitation written by T. B. Bolton and published by . This book was released on 1996 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a compendium of the latest electrophysiological research on smooth muscles from an international collection of authors. It includes recent discoveries in calcium stores and their relationship to contraction and to electrical changes in the membrane. A major section of the book concentrates on calcium release mechanisms in the cell, their control, and the consequences of calcium release in the cell for membrane events. Smooth Muscle Excitation also covers the effects of chemicals released from adjacent cells. Key Features * State-of-the-art volume that represents a synopsis of all work currently being undertaken in this area throughout the world * Content covers both basic and clinical research * Provides a range of drug development studies * Presents contributions from many internationally recognized smooth muscle physiologists

Excitation-Contraction Coupling in Skeletal, Cardiac, and Smooth Muscle

Author : George B. Frank
Publisher : Springer Science & Business Media
ISBN 13 : 1461533627
Total Pages : 450 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Excitation-Contraction Coupling in Skeletal, Cardiac, and Smooth Muscle by : George B. Frank

Download or read book Excitation-Contraction Coupling in Skeletal, Cardiac, and Smooth Muscle written by George B. Frank and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Third International Symposium on Excitation-Contraction Coupling in Skeletal, Cardiac, and Smooth Muscle, organized by George Frank, C. Paul Bianchi, and Henk E. DJ. ter Keurs, was held in Banff Centre, Banff, Alberta, Canada during June 26 to June 30, 1991. The theme of these symposia has been to recognize the similarities and dissimilarities of excitation-contraction coupling in skeletal, cardiac, and smooth muscle. Cross fertilization of concepts of excitation-contraction coupling in these three types of muscle has occurred since the early studies in the late fifties and early sixties on skeletal muscle. Investigators in each field meet only at specialized symposia which exclude investigators in the other fields. The purpose of the symposia has been to bring together international investigators studying excitation-contraction coupling in skeletal, cardiac, and smooth muscle so that we may learn from each other and hence provide a more global concept of excitation-contraction. The Third International Symposia has accomplished its objective as we recognize that calcium channels of the sarcolemma and the sarcoplasmic reticulum play key essential roles in excitation-contraction coupling in all three types of muscles. In skeletal muscle the recognition that E-C coupling consists of two parallel mechanisms, one dependent upon a dihydropyridine voltage-sensitive sensors coupled to calcium release from the terminal cisternae via the ryanodine sensitive channel in the foot structure of the triad.

Excitation-Contraction Coupling and Cardiac Contractile Force

Author : Donald Bers
Publisher : Springer Science & Business Media
ISBN 13 : 9780792371588
Total Pages : 458 pages
Book Rating : 4.3/5 (715 download)

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Book Synopsis Excitation-Contraction Coupling and Cardiac Contractile Force by : Donald Bers

Download or read book Excitation-Contraction Coupling and Cardiac Contractile Force written by Donald Bers and published by Springer Science & Business Media. This book was released on 2001-08-31 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: How is the heartbeat generated? What controls the strength of contraction of heart muscle? What are the links between cardiac structure and function? How does our understanding of skeletal and smooth muscle and non-muscle cells influence our thinking about force development in the heart? Are there important species differences in how contraction is regulated in the heart? How do the new molecular data fit together in understanding the heart beat? What goes wrong in ischemia, hypertrophy, and heart failure? This book paints a modern `portrait' of how the heart works and in this picture the author shows a close-up of the structural, biochemical, and physiological links between excitation and contraction. The author takes the reader through a series of important, interrelated topics with great clarity and continuity and also includes many useful illustrations and tables. The book starts by considering the cellular structures involved in excitation-contraction coupling and then described the characteristics of the myofilaments as the end effector of excitation-contraction coupling. A general scheme of calcium regulation is described and the possible sources and sinks of calcium are discussed in simple, but quantitative terms. The cardiac action potential and its many underlying currents are reviewed. Then the characteristics of some key calcium transport systems (calcium channels, sodium/calcium exchange and SR calcium uptake and release) are discussed in detail. This is then built into a more integrated picture of calcium regulation in succeeding chapters by detailed discussions of excitation-calcium coupling mechanisms (in skeletal, cardiac, and smooth muscle), the interplay between calcium regulatory processes, and finally mechanisms of cardiac inotropy, calcium overload, and dysfunction (e.g., ischemia, hypertrophy, and heart failure). Excitation-Contraction Coupling and Cardiac Contractile Force – Second Edition is an invaluable source of information for anyone who is interested in how the heart beat is controlled and especially suited for students of the cardiovascular system at all levels from medical/graduate students through senior investigators in related fields.

Keynes & Aidley's Nerve and Muscle

Author : Christopher L.-H. Huang
Publisher : Cambridge University Press
ISBN 13 : 1108495052
Total Pages : 327 pages
Book Rating : 4.1/5 (84 download)

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Book Synopsis Keynes & Aidley's Nerve and Muscle by : Christopher L.-H. Huang

Download or read book Keynes & Aidley's Nerve and Muscle written by Christopher L.-H. Huang and published by Cambridge University Press. This book was released on 2020-11-19 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: A complete, yet accessible and up-to-date, introduction to the cellular physiology of nerve, and skeletal, cardiac and smooth muscle.

Colonic Motility

Author : Sushil K. Sarna
Publisher : Biota Publishing
ISBN 13 : 1615041516
Total Pages : 159 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Colonic Motility by : Sushil K. Sarna

Download or read book Colonic Motility written by Sushil K. Sarna and published by Biota Publishing. This book was released on 2010-11-01 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: Three distinct types of contractions perform colonic motility functions. Rhythmic phasic contractions (RPCs) cause slow net distal propulsion with extensive mixing/turning over. Infrequently occurring giant migrating contractions (GMCs) produce mass movements. Tonic contractions aid RPCs in their motor function. The spatiotemporal patterns of these contractions differ markedly. The amplitude and distance of propagation of a GMC are several-fold larger than those of an RPC. The enteric neurons and smooth muscle cells are the core regulators of all three types of contractions. The regulation of contractions by these mechanisms is modifiable by extrinsic factors: CNS, autonomic neurons, hormones, inflammatory mediators, and stress mediators. Only the GMCs produce descending inhibition, which accommodates the large bolus being propelled without increasing muscle tone. The strong compression of the colon wall generates afferent signals that are below nociceptive threshold in healthy subjects. However, these signals become nociceptive; if the amplitudes of GMCs increase, afferent nerves become hypersensitive, or descending inhibition is impaired. The GMCs also provide the force for rapid propulsion of feces and descending inhibition to relax the internal anal sphincter during defecation. The dysregulation of GMCs is a major factor in colonic motility disorders: irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and diverticular disease (DD). Frequent mass movements by GMCs cause diarrhea in diarrhea predominant IBS, IBD, and DD, while a decrease in the frequency of GMCs causes constipation. The GMCs generate the afferent signals for intermittent short-lived episodes of abdominal cramping in these disorders. Epigenetic dysregulation due to adverse events in early life is one of the major factors in generating the symptoms of IBS in adulthood.

Smooth Muscle Spontaneous Activity

Author : Hikaru Hashitani
Publisher : Springer
ISBN 13 : 9811358958
Total Pages : 434 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Smooth Muscle Spontaneous Activity by : Hikaru Hashitani

Download or read book Smooth Muscle Spontaneous Activity written by Hikaru Hashitani and published by Springer. This book was released on 2019-06-10 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the commonality and heterogeneity of the mechanisms underlying smooth muscle spontaneous activity in various smooth muscle organs and in addition discusses their malfunctions in disease and their potential as novel therapeutic targets. To facilitate understanding, the volume is divided into five parts and covers 16 organs: airways, gastrointestinal tract (phasic muscle, tonic muscle), renal pelvis, ureter, urinary bladder, urethra, corporal tissue, prostate, uterus, oviducts, seminal vesicle, artery, vein, microvasculature, and lymphatic vessels. This structure will help readers to comprehend the most up-to-date information on the similarities and differences in the contractile mechanisms driving various smooth muscles as well as their potential manipulations in particular visceral organ pathologies. The vast advancements in gene, electrical recording, and imaging technologies in this field are also discussed, with review of past achievements and consideration of likely future developments. This book will be of worldwide interest to clinicians, students, and researchers alike.

Nerve and Muscle

Author : R. D. Keynes
Publisher : Cambridge University Press
ISBN 13 : 9780521805841
Total Pages : 196 pages
Book Rating : 4.8/5 (58 download)

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Book Synopsis Nerve and Muscle by : R. D. Keynes

Download or read book Nerve and Muscle written by R. D. Keynes and published by Cambridge University Press. This book was released on 2001-03-15 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential textbook for all undergraduate students of neurobiology, physiology, cell biology and preclinical medicine.

Fundamentals of Anaesthesia

Author : Colin Pinnock
Publisher : Cambridge University Press
ISBN 13 : 9780521690799
Total Pages : 990 pages
Book Rating : 4.6/5 (97 download)

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Book Synopsis Fundamentals of Anaesthesia by : Colin Pinnock

Download or read book Fundamentals of Anaesthesia written by Colin Pinnock and published by Cambridge University Press. This book was released on 2002-12 with total page 990 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Fundamentals of Anaesthesia builds upon the success of the first edition, and encapsulates the modern practice of anaesthesia in a single volume. Written and edited by a team of expert contributors, it provides a comprehensive but easily readable account of all of the information required by the FRCA Primary examination candidate and has been expanded to include more detail on all topics and to include new topics now covered in the examination. As with the previous edition, presentation of information is clear and concise, with the use of lists, tables, summary boxes and line illustrations where necessary to highlight important information and aid the understanding of complex topics. Great care has been taken to ensure an unrivalled consistency of style and presentation throughout.

Core Topics in Cardiac Anesthesia

Author : Jonathan H. Mackay
Publisher : Cambridge University Press
ISBN 13 : 9780521196857
Total Pages : 0 pages
Book Rating : 4.1/5 (968 download)

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Book Synopsis Core Topics in Cardiac Anesthesia by : Jonathan H. Mackay

Download or read book Core Topics in Cardiac Anesthesia written by Jonathan H. Mackay and published by Cambridge University Press. This book was released on 2012-03-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the first edition of Core Topics in Cardiac Anaesthesia, the clinical landscape has undergone significant change. Recent developments include the increased use of electrophysiology, the resurgence of primary percutaneous intervention in acute coronary syndromes, the use of percutaneous devices in patients previously considered inoperable, and the withdrawal of aprotinin. Against this landscape, this invaluable resource has been fully updated. New chapters are dedicated to right heart valves, pulmonary vascular disease, cardiac tumours and cardiac trauma. All other chapters have been updated according to the latest international guidelines. Written and edited by an international author team with a wealth of expertise in all aspects of the perioperative care of cardiac patients, topics are presented in an easy to digest and a readily accessible manner. Core Topics in Cardiac Anaesthesia, Second Edition is essential reading for residents and fellows in anaesthesia and cardiac surgery and clinical perfusionists.

Functional Movement Development Across the Life Span

Author : Donna Joy Cech
Publisher : Elsevier Health Sciences
ISBN 13 : 1437715486
Total Pages : 385 pages
Book Rating : 4.4/5 (377 download)

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Book Synopsis Functional Movement Development Across the Life Span by : Donna Joy Cech

Download or read book Functional Movement Development Across the Life Span written by Donna Joy Cech and published by Elsevier Health Sciences. This book was released on 2011-09-06 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing a solid foundation in the normal development of functional movement, Functional Movement Development Across the Life Span, 3rd Edition helps you recognize and understand movement disorders and effectively manage patients with abnormal motor function. It begins with coverage of basic theory, motor development and motor control, and evaluation of function, then discusses the body systems contributing to functional movement, and defines functional movement outcomes in terms of age, vital functions, posture and balance, locomotion, prehension, and health and illness. This edition includes more clinical examples and applications, and updates data relating to typical performance on standardized tests of balance. Written by physical therapy experts Donna J. Cech and Suzanne "Tink" Martin, this book provides evidence-based information and tools you need to understand functional movement and manage patients' functional skills throughout the life span. - Over 200 illustrations, tables, and special features clarify developmental concepts, address clinical implications, and summarize key points relating to clinical practice. - A focus on evidence-based information covers development changes across the life span and how they impact function. - A logical, easy-to-read format includes 15 chapters organized into three units covering basics, body systems, and age-related functional outcomes respectively. - Expanded integration of ICF (International Classification of Function) aligns learning and critical thinking with current health care models. - Additional clinical examples help you apply developmental information to clinical practice. - Expanded content on assessment of function now includes discussion of participation level standardized assessments and assessments of quality-of-life scales. - More concise information on the normal anatomy and physiology of each body system allows a sharper focus on development changes across the lifespan and how they impact function.

Mechanisms of Vascular Disease

Author : Robert Fitridge
Publisher : University of Adelaide Press
ISBN 13 : 1922064009
Total Pages : 589 pages
Book Rating : 4.9/5 (22 download)

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Book Synopsis Mechanisms of Vascular Disease by : Robert Fitridge

Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Anatomy & Physiology

Author : Lindsay Biga
Publisher :
ISBN 13 : 9781955101158
Total Pages : pages
Book Rating : 4.1/5 (11 download)

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Book Synopsis Anatomy & Physiology by : Lindsay Biga

Download or read book Anatomy & Physiology written by Lindsay Biga and published by . This book was released on 2019-09-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: A version of the OpenStax text

Basic Physiology for Anaesthetists

Author : David Chambers
Publisher : Cambridge University Press
ISBN 13 : 1108463991
Total Pages : 469 pages
Book Rating : 4.1/5 (84 download)

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Book Synopsis Basic Physiology for Anaesthetists by : David Chambers

Download or read book Basic Physiology for Anaesthetists written by David Chambers and published by Cambridge University Press. This book was released on 2019-07-25 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: Easily understood, up-to-date and clinically relevant, this book provides junior anaesthetists with an essential physiology resource.

Anatomy and Physiology

Author : J. Gordon Betts
Publisher :
ISBN 13 : 9781947172807
Total Pages : 0 pages
Book Rating : 4.1/5 (728 download)

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Book Synopsis Anatomy and Physiology by : J. Gordon Betts

Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Signal Transduction and Smooth Muscle

Author : Mohamed Trebak
Publisher : CRC Press
ISBN 13 : 1351650610
Total Pages : 326 pages
Book Rating : 4.3/5 (516 download)

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Book Synopsis Signal Transduction and Smooth Muscle by : Mohamed Trebak

Download or read book Signal Transduction and Smooth Muscle written by Mohamed Trebak and published by CRC Press. This book was released on 2018-08-06 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: All hollow organs, such as blood vessels, the gastrointestinal tract, airways, male and female reproductive systems, and the urinary bladder are primarily composed of smooth muscle. Such organs regulate flow, propulsion and mixing of luminal contents and storage by the contraction and relaxation of smooth muscle cells. Smooth muscle cells respond to numerous inputs, including pressure, shear stress, intrinsic and extrinsic innervation, hormones and other circulating molecules, as well as autocrine and paracrine factors. This book is a review of smooth muscle cell regulation in the cardiovascular, reproductive, GI, and other organ systems with emphasis on calcium and receptor signaling. Key selling features: Focuses on smooth muscles of different types Describes ion channel signaling mechanisms Reviews calcium and receptor signaling Includes novel, cutting-edge methodologies Summarizes studies of mice with genetically encoding sensors in smooth muscle Chapter 9 of this book is freely available as a downloadable Open Access PDF under a CC-BY 4.0 license. https://s3-us-west-2.amazonaws.com/tandfbis/rt-files/docs/Open+Access+Chapters/9781498774222_oachapter9.pdf

Sports-Specific Rehabilitation

Author : Robert A. Donatelli, PhD, PT, OCS
Publisher : Elsevier Health Sciences
ISBN 13 : 0443066426
Total Pages : 368 pages
Book Rating : 4.4/5 (43 download)

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Book Synopsis Sports-Specific Rehabilitation by : Robert A. Donatelli, PhD, PT, OCS

Download or read book Sports-Specific Rehabilitation written by Robert A. Donatelli, PhD, PT, OCS and published by Elsevier Health Sciences. This book was released on 2006-10-11 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive resource for focusing on returning injured athletes to their optimal performance! This book discusses exercise principles; muscle fatigue, muscle damage, and overtraining concepts; pathophysiology of overuse injuries; core evaluation in sports-specific testing; physiological basis of exercise specific to sport; and special considerations for the athlete. Secial features such as evidence-based clinical application boxes provide the reader with a solid body of research upon which to base their practice. Aligned to the Guide to Physical Therapy Practice to help learn how to work with athletes' injuries and help them make a physical comeback while following best practices. Incorporation of muscle physiology demonstrates it as the basis for athlete's exercise prescription. Coverage of pathophysiology of overuse injuries illustrates the damage to the musculoskeletal system. Inclusion of treatment and training approaches for athletic rehabilitation shows how to restore the musculoskeletal system back to full flexibility, strength, power, and endurance. Evidence-based clinical application boxes found throughout the book cite key studies and provide real-world application to a clinical setting. Extensive photographs show hands-on demonstrations of important rehabilitation techniques, helping the cinician to accurately apply them during treatment.

Muscle Cells

Author : Mani T. Valarmathi
Publisher : BoD – Books on Demand
ISBN 13 : 1789239672
Total Pages : 182 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Muscle Cells by : Mani T. Valarmathi

Download or read book Muscle Cells written by Mani T. Valarmathi and published by BoD – Books on Demand. This book was released on 2020-01-22 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: The three different types of muscle tissue found in the animal kingdom are cardiac, skeletal, and smooth. The muscle cells are not only complex but also fascinating. In recent years there has been substantial advances in our understanding of muscle cell biology, especially in areas of molecular anatomy, basic physiology, understanding disease mechanisms, and therapeutic targets. Consequently, this book mainly focuses not only on the biology of myocytes, but also on all-encompassing disciplines pertaining to muscle tissue, such as fundamental physiology, molecular mechanisms of diseases, muscle regeneration, etc. for all three types of muscle, namely, skeletal, cardiac, and smooth muscle. As a result, the goal of this book is to consolidate the recent advances in the area of muscle biology/diseases/regeneration covering a broad range of interrelated topics in a timely fashion and to disseminate that knowledge in a lucid way to a greater scientific audience. This book will prove highly useful for students, researchers, and clinicians in muscle cell biology, exercise physiology/science, stem cell biology, developmental biology, cancer biology, pathology, oncology, as well as tissue engineering and regenerative medicine. This quick reference will benefit anyone desiring a thorough knowledge pertaining to recent advances in muscle biology in the context of health and disease.