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Examining Tissue Microstructure With Temporal Diffusion Magnetic Resonance Spectroscopy
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Book Synopsis Examining Tissue Microstructure with Temporal Diffusion Magnetic Resonance Spectroscopy by : Daniel Christopher Colvin
Download or read book Examining Tissue Microstructure with Temporal Diffusion Magnetic Resonance Spectroscopy written by Daniel Christopher Colvin and published by . This book was released on 2009 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Assessing Cellular Microstructure in Biological Tissues using In Vivo Diffusion-Weighted Magnetic Resonance by : Julien Valette
Download or read book Assessing Cellular Microstructure in Biological Tissues using In Vivo Diffusion-Weighted Magnetic Resonance written by Julien Valette and published by Frontiers Media SA. This book was released on 2019-05-16 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic resonance imaging (MRI) and spectroscopy (MRS) techniques have opened new doors for examining biological tissues in vivo. By combining sensitization to diffusion using magnetic field gradients with a variety of imaging and localization schemes, diffusion-weighted MRI and diffusion-weighted MRS allow investigating translational diffusion of endogenous molecules, such as water or metabolites, in biological tissues, most commonly the brain but also other organs such as the prostate. The typical voxel resolution of MRI or MRS is in the millimeter to centimeter range, much lower than the cellular scale. However, as molecules are typically diffusing over just a few µm during the duration of the measurement (the “diffusion time”) and encounter numerous biological membranes at these scales, the average cellular microstructure has a critical influence on the measured diffusion signal. Hence, diffusion-weighted MRI and diffusion-weighted MRS are sensitive to tissue microstructure at a scale well below the nominal imaging resolution. However, the connection between diffusion properties and tissue microstructure remains indirect, so any attempt to quantify microstructure will rely on modeling. The goal of this Research Topic was to gather experts in various acquisition and modeling strategies and show how these approaches, despite their own strengths and weaknesses, can yield unique information about cellular microstructure, and sometimes complement each other.
Book Synopsis Towards Quantitative Measurements of Tissue Microstructure Using Temporal Diffusion Spectroscopy by : Hua Li
Download or read book Towards Quantitative Measurements of Tissue Microstructure Using Temporal Diffusion Spectroscopy written by Hua Li and published by . This book was released on 2015 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Diffusion Weighted Magnetic Resonance Imaging by Temporal Diffusion Spectroscopy by : Junzhong Xu
Download or read book Diffusion Weighted Magnetic Resonance Imaging by Temporal Diffusion Spectroscopy written by Junzhong Xu and published by . This book was released on 2008 with total page 85 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Advanced Magnetic Resonance Spectroscopy Techniques and Applications by : Peng Cao
Download or read book Advanced Magnetic Resonance Spectroscopy Techniques and Applications written by Peng Cao and published by Open Dissertation Press. This book was released on 2017-01-27 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Advanced Magnetic Resonance Spectroscopy Techniques and Applications" by Peng, Cao, 曹鹏, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Magnetic resonance (MR) is a well-known non-invasive technique that provides spectra (by MR spectroscopy, MRS) and images (by magnetic resonance imaging, MRI) of the examined tissue with detailed metabolic, structural, and functional information. This doctoral work is focused on advanced methodologies and applications of MRS for probing cellular and molecular changes in vivo. A single-voxel diffusion-weighted (DW) MRS method was first developed for monitoring the size changes of intramyocellular lipid droplets in vivo. This DWMRS technique was then utilized for exploring the vascular origins of the functional blood-oxygen-level-dependent (BOLD) signal. Magnetic resonance spectroscopic imaging (MRSI) enables simultaneous MRS acquisition in multiple voxels. However, MRSI is conventionally time-consuming. Therefore, a compressed sensing (CS) method was proposed in this thesis to accelerate the acquisition speed of the in vivo MRSI. It holds the potential for promoting the realization of multiple-voxel DW-MRS experiments, though the latter is still constrained by hardware in the present. The single-voxel DW-MRS method for probing lipid diffusion was first developed and evaluated in oil and muscle phantoms. The experimental sequence was demonstrated to be sensitive to diffusion restriction and free of significant artifacts. Experiments were then performed in rat hindlimb muscles in vivo. The restricted lipid diffusion behavior was characterized by apparent diffusion coefficient (ADC) changes and utilized for quantifying the sizes of intramyocellular lipid (IMCL) droplets in normal, fasting, diabetic and obese rats. The sizes of IMCL droplets reflect their vital roles in muscle energy metabolism. The IMCL droplet size estimated by ADC here was closely correlated with that measured by transmission electron microscopy. IMCL ADC was sensitive to metabolic alterations, decreasing in the fasting and diabetic groups while increasing in the obese group. These results clearly demonstrate DW MRS as a new means to examine the dynamics of IMCL metabolism in vivo. The DW-MRS technique was then utilized to characterize water ADC during neuronal activation to explore the vascular origins of the BOLD signal in rat brains. MRS experiments with acoustic stimulation were performed with a dynamic point-resolved spectroscopy (PRESS) acquisition on conditions with or without the diffusion gradient for blood suppression in the same voxel and same experimental session, which enabled the simultaneous T2/T2*/diffusion measurements. The T2*% changes with and without diffusion gradient showed no significant difference, while the spin echo (SE)-BOLD% (T2%) change significantly decreased after applying the diffusion gradient, suggesting an intravascular component in the SE-BOLD signal. This intravascular component was not venous blood, as the T2* of this component was comparable with the T2* of the brain tissue. These results provide new insights into the vascular origins of BOLD signals. A CS approach was developed to accelerate in vivo magnetic resonance spectroscopic imaging (MRSI) which enables multi-voxel MRS measurements. The CS undersampling was performed by acquiring a pseudo-random and density-varying subset of phase encodings. The proposed CS approach preserved the spectral and spatial resolution, while substantially reduced the number of phase encodings with accelerations up to seven fold for phantom and up to six fold
Book Synopsis Investigating Microstructure in the Brain Using Diffusion Weighted Magnetic Resonance Imaging by : Seyed Hamed Yousefi Mesri
Download or read book Investigating Microstructure in the Brain Using Diffusion Weighted Magnetic Resonance Imaging written by Seyed Hamed Yousefi Mesri and published by . This book was released on 2014 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Investigation of Biological Tissues by Diffusion Weighted Magnetic Resonance Spectroscopy by : 王旻
Download or read book Investigation of Biological Tissues by Diffusion Weighted Magnetic Resonance Spectroscopy written by 王旻 and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Methods of Diffusion-weighted MR Spectroscopy as a Probe for Brain-tissue-microstructure by : Andre Doering
Download or read book Methods of Diffusion-weighted MR Spectroscopy as a Probe for Brain-tissue-microstructure written by Andre Doering and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Brain Network Analysis by : Moo K. Chung
Download or read book Brain Network Analysis written by Moo K. Chung and published by Cambridge University Press. This book was released on 2019-06-27 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: This coherent mathematical and statistical approach aimed at graduate students incorporates regression and topology as well as graph theory.
Book Synopsis Introduction to Diffusion Tensor Imaging by : Susumu Mori
Download or read book Introduction to Diffusion Tensor Imaging written by Susumu Mori and published by Academic Press. This book was released on 2013-08-02 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concepts behind diffusion tensor imaging (DTI) are commonly difficult to grasp, even for magnetic resonance physicists. To make matters worse, a many more complex higher-order methods have been proposed over the last few years to overcome the now well-known deficiencies of DTI. In Introduction to Diffusion Tensor Imaging: And Higher Order Models, these concepts are explained through extensive use of illustrations rather than equations to help readers gain a more intuitive understanding of the inner workings of these techniques. Emphasis is placed on the interpretation of DTI images and tractography results, the design of experiments, and the types of application studies that can be undertaken. Diffusion MRI is a very active field of research, and theories and techniques are constantly evolving. To make sense of this constantly shifting landscape, there is a need for a textbook that explains the concepts behind how these techniques work in a way that is easy and intuitive to understand—Introduction to Diffusion Tensor Imaging fills this gap. Extensive use of illustrations to explain the concepts of diffusion tensor imaging and related methods Easy to understand, even without a background in physics Includes sections on image interpretation, experimental design, and applications Up-to-date information on more recent higher-order models, which are increasingly being used for clinical applications
Book Synopsis Quantitative Magnetic Resonance Imaging by : Nicole Seiberlich
Download or read book Quantitative Magnetic Resonance Imaging written by Nicole Seiberlich and published by Academic Press. This book was released on 2020-11-18 with total page 1094 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative Magnetic Resonance Imaging is a ‘go-to’ reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: The basic physics behind tissue property mapping How to implement basic pulse sequences for the quantitative measurement of tissue properties The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* The pros and cons for different approaches to mapping perfusion The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor maps and more complex representations of diffusion How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance Fingerprinting can be used to accelerate or improve tissue property mapping schemes How tissue property mapping is used clinically in different organs Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches
Book Synopsis Visualization and Processing of Tensor Fields by : David H. Laidlaw
Download or read book Visualization and Processing of Tensor Fields written by David H. Laidlaw and published by Springer Science & Business Media. This book was released on 2009-03-30 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides researchers an inspirational look at how to process and visualize complicated 2D and 3D images known as tensor fields. With numerous color figures, it details both the underlying mathematics and the applications of tensor fields.
Author :Committee on the Mathematics and Physics of Emerging Dynamic Biomedical Imaging Publisher :National Academies Press ISBN 13 :0309552923 Total Pages :261 pages Book Rating :4.3/5 (95 download)
Book Synopsis Mathematics and Physics of Emerging Biomedical Imaging by : Committee on the Mathematics and Physics of Emerging Dynamic Biomedical Imaging
Download or read book Mathematics and Physics of Emerging Biomedical Imaging written by Committee on the Mathematics and Physics of Emerging Dynamic Biomedical Imaging and published by National Academies Press. This book was released on 1996-03-13 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: This cross-disciplinary book documents the key research challenges in the mathematical sciences and physics that could enable the economical development of novel biomedical imaging devices. It is hoped that the infusion of new insights from mathematical scientists and physicists will accelerate progress in imaging. Incorporating input from dozens of biomedical researchers who described what they perceived as key open problems of imaging that are amenable to attack by mathematical scientists and physicists, this book introduces the frontiers of biomedical imaging, especially the imaging of dynamic physiological functions, to the educated nonspecialist. Ten imaging modalities are covered, from the well-established (e.g., CAT scanning, MRI) to the more speculative (e.g., electrical and magnetic source imaging). For each modality, mathematics and physics research challenges are identified and a short list of suggested reading offered. Two additional chapters offer visions of the next generation of surgical and interventional techniques and of image processing. A final chapter provides an overview of mathematical issues that cut across the various modalities.
Download or read book Diffusion MRI written by Derek K Jones and published by Oxford University Press. This book was released on 2010-11-11 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: Professor Derek Jones, a world authority on diffusion MRI, has assembled most of the world's leading scientists and clinicians developing and applying diffusion MRI to produce an authorship list that reads like a "Who's Who" of the field and an essential resource for those working with diffusion MRI. Destined to be a modern classic, this definitive and richly illustrated work covers all aspects of diffusion MRI from basic theory to clinical application. Oxford Clinical Neuroscience is a comprehensive, cross-searchable collection of resources offering quick and easy access to eleven of Oxford University Press's prestigious neuroscience texts. Joining Oxford Medicine Online these resources offer students, specialists and clinical researchers the best quality content in an easy-to-access format.
Book Synopsis Psychiatric Neuroimaging by : Virginia Ng
Download or read book Psychiatric Neuroimaging written by Virginia Ng and published by IOS Press. This book was released on 2003 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis New Techniques for Management of ‘Inoperable’ Gliomas by : Michael E. Sughrue
Download or read book New Techniques for Management of ‘Inoperable’ Gliomas written by Michael E. Sughrue and published by Academic Press. This book was released on 2019-08-03 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Techniques for Management of 'Inoperable' Gliomas radically challenges the assumption that certain gliomas cannot be removed with modern techniques, contesting stereotypical thinking and establishing new paradigms in the field. Gliomas are primary brain tumors which are often fatal. Recent data has demonstrated that despite the fact that surgery cannot cure gliomas, patient survival is substantially improved by removing as much of the tumor as possible. This fact has raised the imperative that neurologists try to improve techniques to bring surgical resection to as many patients as possible. This book brings new insights and technologies to the forefront, giving hope to patients. Provides the first comprehensive book to discuss techniques for removing gliomas that are traditionally deemed ‘inoperable’ Presents a great reference tool that challenges stereotypical thinking by offering techniques by innovative surgeons Includes chapters that are organized by different glioma types and surgery/techniques
Book Synopsis Neuroimaging in Developmental Clinical Neuroscience by : Judith M. Rumsey
Download or read book Neuroimaging in Developmental Clinical Neuroscience written by Judith M. Rumsey and published by Cambridge University Press. This book was released on 2009-02-19 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern neuroimaging offers tremendous opportunities for gaining insights into normative development and a wide array of developmental neuropsychiatric disorders. Focusing on ontogeny, this text covers basic processes involved in both healthy and atypical maturation, and also addresses the range of neuroimaging techniques most widely used for studying children. This book will enable you to understand normative structural and functional brain maturation and the mechanisms underlying basic developmental processes; become familiar with current knowledge and hypotheses concerning the neural bases of developmental neuropsychiatric disorders; and learn about neuroimaging techniques, including their unique strengths and limitations. Coverage includes normal developmental processes, atypical processing in developmental neuropsychiatric disorders, ethical issues, neuroimaging techniques and their integration with psychopharmacologic and molecular genetic research approaches, and future directions. This comprehensive volume is an essential resource for neurologists, neuropsychologists, psychiatrists, pediatricians, and radiologists concerned with normal development and developmental neuropsychiatric disorders.
