A National Cancer Clinical Trials System for the 21st Century

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Author :
Publisher : National Academies Press
ISBN 13 : 0309157870
Total Pages : 317 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis A National Cancer Clinical Trials System for the 21st Century by : Institute of Medicine

Download or read book A National Cancer Clinical Trials System for the 21st Century written by Institute of Medicine and published by National Academies Press. This book was released on 2010-07-08 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: The National Cancer Institute's (NCI) Clinical Trials Cooperative Group Program has played a key role in developing new and improved cancer therapies. However, the program is falling short of its potential, and the IOM recommends changes that aim to transform the Cooperative Group Program into a dynamic system that efficiently responds to emerging scientific knowledge; involves broad cooperation of stakeholders; and leverages evolving technologies to provide high-quality, practice-changing research.

Screening and Risk Reduction Strategies for Breast Cancer

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Author :
Publisher : Springer Nature
ISBN 13 : 9811976309
Total Pages : 191 pages
Book Rating : 4.8/5 (119 download)

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Book Synopsis Screening and Risk Reduction Strategies for Breast Cancer by : Masakazu Toi

Download or read book Screening and Risk Reduction Strategies for Breast Cancer written by Masakazu Toi and published by Springer Nature. This book was released on 2023-03-01 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides readers with the most up-to-date practical information on breast cancer screening. Since breast cancers are highly heterogeneous, time to clinical onset from the initial carcinogenesis differs diversely between cancers. Pathological germline variants and driver mutations cause a high lifetime risk of breast cancer. The lifetime risks are various according to what genes are pathologically dysfunctional. Integrated omics and imaging technologies have established varying tumour characteristics. Thus, this book suggests that a more individualised scheme is required to improve breast cancer screening. A key aim is to demonstrate how multiple diagnostic imaging modalities such as mammography, ultrasonography, MRI, PET and dbPET improve breast cancer screening accuracy. Mammography screening alone may have a limited impact on breast cancer risk prediction. These issues are crucial to discuss. Clinical experts recommend that new modalities be incorporated for women with dense breasts, like ultrasonography, dynamic mammography, MRI and maybe breast-dedicated PET. Topics on these modalities are going to be summarized in this book. An in-depth review of these modalities is summarised in this book. In addition, new diagnostic modalities, including risk assessment tools, multi-cancer early detection tests using liquid biopsy, the role of protein biomarkers in breast cancer risk screening, challenges, and hopes for future advances, are also covered in this book.

Support and aspiration

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Publisher : The Stationery Office
ISBN 13 : 9780101802727
Total Pages : 136 pages
Book Rating : 4.8/5 (27 download)

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Book Synopsis Support and aspiration by : Great Britain: Department for Education

Download or read book Support and aspiration written by Great Britain: Department for Education and published by The Stationery Office. This book was released on 2011-03-09 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report unveils proposals for the biggest programme of reform in the education and health support for children with special educational needs (SEN) and disabilities in 30 years. The Government wants to fundamentally reform the SEN system to address problems including: parents having to battle to get the support their child needs; SEN statements not joining up education, health and care support; children falling between the gaps in services or having to undergo multiple assessments; multiple layers of paperwork and bureaucracy adding delays to getting support, therapy and vital equipment; confusing and adversarial assessment process, with the perceived conflict of interest where the local authority must provide SEN support as well as assess children's needs; too many children are being over-identified as SEN, preventing them from achieving their potential because teachers have lower expectations of them. The Government proposes to: include parents in the assessment process and introduce a legal right, by 2014, to give them control of funding for the support their child needs; replace statements with a single assessment process and a combined education, health and care plan so that health and social services is included in the package of support; ensure assessment and plans run from birth to 25 years old; replace the existing complicated School Action and School Action Plus system with a simpler new school-based category to help teachers focus on raising attainment; overhaul teacher training and professional development; inject greater independence from local authorities in assessments; give parents a greater choice of school and the power to set up special free schools

Personalised Health Care

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Author :
Publisher : Springer Nature
ISBN 13 : 3030523993
Total Pages : 135 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Personalised Health Care by : Stefania Boccia

Download or read book Personalised Health Care written by Stefania Boccia and published by Springer Nature. This book was released on 2020-11-23 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practitioners are increasingly adopting a personalised medicine approach to individually tailored patient care, especially disease diagnosis and treatment with the use of biomarkers. However, development and implementation of such approaches to chronic disease prevention need further investigation and concerted efforts for proper use in healthcare systems. This book provides high-quality, multidisciplinary knowledge from research in personalised medicine, specifically personalised prevention of chronic disease. It addresses different perspectives of prevention in the field, and is the outcome of a four-year work of the Personalized prevention of Chronic Disease (PRECeDI) Consortium, a multi-disciplinary and multi-professional team of experts. The Consortium jointly agreed to document and address the five aspects or domains of personalised medicine and prevention as individual chapters: Identification of biomarkers for the prevention of chronic disease Evaluation of predictive genomic applications Ethico-legal and policy issues surrounding personalised medicine Roles and responsibilities of stakeholders in informing healthy individuals on their genome: a sociotechnical analysis Identification of organisational models for the provision of predictive genomic applications The book focuses on the Consortium's recommendations that are derived from each of these domains based on up-to-date evidence and research that the authors write, follow, and systematically organise and report. Personalisation of health care is, eventually, a driver of innovation in research and healthcare systems. With this SpringerBrief on Personalised Health Care: Fostering Precision Medicine Advancements for Gaining Population Health Impact, the Consortium provides further evidence of the clinical validity and utility of personalised medicine with special emphasis on the prevention of chronic diseases. The book is a useful resource for policy makers, industry and healthcare professionals, scientists, technology-sector professionals, investors, citizens, and private companies that need proper advice to realise the potential of personalised medicine.

Delivering Personal Health Budgets

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Author :
Publisher : Policy Press
ISBN 13 : 1447312163
Total Pages : 129 pages
Book Rating : 4.4/5 (473 download)

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Book Synopsis Delivering Personal Health Budgets by : Alakeson, Vidhya

Download or read book Delivering Personal Health Budgets written by Alakeson, Vidhya and published by Policy Press. This book was released on 2014-01-07 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt: Personal health budgets are an important new tool to improve the lives of people living with long-term conditions and disabilities by giving them greater choice and control over their healthcare.This is the first step-by-step guide to their implementation. Using current evidence and best practice identified by pilot sites, Delivering personal health budgets contains everything there is to know about the purpose and history of personal health budgets, the evidence for their effectiveness and the challenges they pose to traditional healthcare systems. It describes the essential infrastructure needed for personal health budgets and includes implementation checklists.The book focuses on how personal health budgets can be implemented to achieve the best possible outcomes for individuals, while real life stories from personal health budget holders bring their potential vividly to life. Delivering personal health budgets is essential reading for commissioners, healthcare providers, clinicians and policy makers who are looking for an informative and authoritative guide.

SFPE Guide to Human Behavior in Fire

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Author :
Publisher : Springer
ISBN 13 : 3319946978
Total Pages : 159 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis SFPE Guide to Human Behavior in Fire by : Society of Fire Protection Engineers

Download or read book SFPE Guide to Human Behavior in Fire written by Society of Fire Protection Engineers and published by Springer. This book was released on 2018-11-14 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: This single resource for the fire safety community distills the most relevant and useful science and research into a consensus-based guide whose key factors and considerations impact the response and behavior of occupants of a building during a fire event. The Second Edition of SFPE's Engineering Guide: Human Behavior in Fire provides a common introduction to this field for the broad fire safety community: fire protection engineers/fire safety engineers, human behavior scientists/researchers, design professionals, and code authorities. The public benefits from consistent understanding of the factors that influence the responses and behaviors of people when threatened by fire and the application of reliable methodologies to evaluate and estimate human response in buildings and structures. This Guide also aims to lessen the uncertainties in the "people components" of fire safety and allow for more refined analysis with less reliance on arbitrary safety factors. As with fire science in general, our knowledge of human behavior in fire is growing, but is still characterized by uncertainties that are traceable to both limitation in the science and unfamiliarity by the user communities. The concepts for development of evacuation scenarios for performance-based designs and the technical methods to estimate evacuation response are reviewed with consideration to the limitation and uncertainty of the methods. This Guide identifies both quantitative and qualitative information that constitutes important consideration prior to developing safety factors, exercising engineering judgment, and using evacuation models in the practical design of buildings and evacuation procedures. Besides updating material in the First Edition, this revision includes new information on: Incapacitating Effects of Fire Effluent & Toxicity Analysis Methods Occupant Behavior Scnearios Movement Models and Behavioral Models Egress Model Selection, Verification, and Validation Estimation of Uncertainty and Use of Safety Factors Enhancing Human Response to Emergencies & Notification of Messaging The prediction of human behavior during a fire emergency is one of the most challenging areas of fire protection engineering. Yet, understanding and considering human factors is essential to designing effective evacuation systems, ensuring safety during a fire and related emergency events, and accurately reconstructing a fire.

Central Nervous System Metastases

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Publisher : Springer Nature
ISBN 13 : 3030234177
Total Pages : 411 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Central Nervous System Metastases by : Manmeet Ahluwalia

Download or read book Central Nervous System Metastases written by Manmeet Ahluwalia and published by Springer Nature. This book was released on 2019-11-05 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of brain metastases, from the molecular biology aspects to therapeutic management and perspectives. Due to the increasing incidence of these tumors and the urgent need to effectively control brain metastatic diseases in these patients, new therapeutic strategies have emerged in recent years. The volume discusses all these innovative approaches combined with new surgical techniques (fluorescence, functional mapping, integrated navigation), novel radiation therapy techniques (stereotactic radiosurgery) and new systemic treatment approaches such as targeted- and immunotherapy. These combination strategies represent a new therapeutic model in brain metastatic patients in which each medical practitioner (neurosurgeon, neurologist, medical oncologist, radiation oncologist) plays a pivotal role in defining the optimal treatment in a multidisciplinary approach. Written by recognized experts in the field, this book is a valuable tool for neurosurgeons, neuro-oncologists, neuroradiologists, medical oncologists, radiation oncologists, cognitive therapists, basic scientists and students working in the area of brain tumors.

Access to Justice

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Publisher : Emerald Group Publishing
ISBN 13 : 1848552432
Total Pages : 288 pages
Book Rating : 4.8/5 (485 download)

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Book Synopsis Access to Justice by : Rebecca L. Sanderfur

Download or read book Access to Justice written by Rebecca L. Sanderfur and published by Emerald Group Publishing. This book was released on 2009-03-23 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Around the world, access to justice enjoys an energetic and passionate resurgence as an object both of scholarly inquiry and political contest, as both a social movement and a value commitment motivating study and action. This work evidences a deeper engagement with social theory than past generations of scholarship.

Pathfinder Associative Networks

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Author :
Publisher : Intellect (UK)
ISBN 13 :
Total Pages : 336 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Pathfinder Associative Networks by : Roger W. Schvaneveldt

Download or read book Pathfinder Associative Networks written by Roger W. Schvaneveldt and published by Intellect (UK). This book was released on 1990 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a presentation of the theory and application of Pathfinder networks. These networks are derived from proximity data, and they have various applications in cognitive modelling, user-computer interface design, and knowledge engineering.

The Martian Chronicles

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Author :
Publisher : Simon and Schuster
ISBN 13 : 1451678193
Total Pages : 256 pages
Book Rating : 4.4/5 (516 download)

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Book Synopsis The Martian Chronicles by : Ray Bradbury

Download or read book The Martian Chronicles written by Ray Bradbury and published by Simon and Schuster. This book was released on 2012-04-17 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: The tranquility of Mars is disrupted by humans who want to conquer space, colonize the planet, and escape a doomed Earth.

Ending Violence Against Women

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Author :
Publisher : Oxfam
ISBN 13 : 9780855984380
Total Pages : 390 pages
Book Rating : 4.9/5 (843 download)

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Book Synopsis Ending Violence Against Women by : Francine Pickup

Download or read book Ending Violence Against Women written by Francine Pickup and published by Oxfam. This book was released on 2001 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: 8. Challenging the state.

Fall of Plaguestone

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Publisher :
ISBN 13 : 9781640781740
Total Pages : 0 pages
Book Rating : 4.7/5 (817 download)

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Book Synopsis Fall of Plaguestone by : Jason Bulmahn

Download or read book Fall of Plaguestone written by Jason Bulmahn and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "A group of new adventurers, traveling through the small community of Plaguestone, must come together to solve the murder of a friend. What starts as simple investigation quickly turns sinister with the discovery of forbidden alchemy, mutant animals, and a nearby forest rotting away due to a mysterious blight. It becomes clear that if these young heroes don't get to the heart of the plot, then the fall of Plaguestone is all but certain! The Fall of Plaguestone is the first Second Edition Pathfinder roleplaying game standalone adventure, taking new players and Game Masters on a daring adventure filled with wilderness exploration, dungeon encounters, and much more! This 64-page softcover adventure is designed for 1st-level characters, built using the rules in the Pathfinder Core Rulebook, facing off against monsters found in the Pathfinder Bestiary. The Fall of Plaguestone is the first Second Edition Pathfinder roleplaying game standalone adventure, taking new players and Game Masters on a daring adventure filled with wilderness exploration, dungeon encounters, and much more! This 64-page softcover adventure is designed for 1st-level characters, built using the rules in the Pathfinder Core Rulebook, facing off against monsters found in the Pathfinder Bestiary. "--Provided by publisher.

Research Methods in Human Development

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Author :
Publisher : WCB/McGraw-Hill
ISBN 13 :
Total Pages : 300 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Research Methods in Human Development by : Paul C. Cozby

Download or read book Research Methods in Human Development written by Paul C. Cozby and published by WCB/McGraw-Hill. This book was released on 1989 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: For undergradute social science majors. A textbook on the interpretation and use of research. Annotation copyright Book News, Inc. Portland, Or.

Thomas Sankara Speaks

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Publisher :
ISBN 13 : 9781776421534
Total Pages : 0 pages
Book Rating : 4.4/5 (215 download)

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Book Synopsis Thomas Sankara Speaks by : Thomas Sankara

Download or read book Thomas Sankara Speaks written by Thomas Sankara and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cumulated Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 1856 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1997 with total page 1856 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Guidelines and Metrics for Assessing Space System Cost Estimates

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Author :
Publisher : RAND Corporation
ISBN 13 :
Total Pages : 268 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Guidelines and Metrics for Assessing Space System Cost Estimates by : Bernard Fox

Download or read book Guidelines and Metrics for Assessing Space System Cost Estimates written by Bernard Fox and published by RAND Corporation. This book was released on 2008 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1. Introduction / 2. Space system fundamentals / 3. Reviewing a cost estimate / 4. Space vehicle cost crosschecks / 5. Common issues in estimating space programs / 6. Resources for space system cost estimation / 7. Recommendations.

Learning, Design, and Technology

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Publisher :
ISBN 13 : 9783319177274
Total Pages : pages
Book Rating : 4.1/5 (772 download)

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Book Synopsis Learning, Design, and Technology by : J. Michael Spector

Download or read book Learning, Design, and Technology written by J. Michael Spector and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: