Epistasis And The Evolutionary Process

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Epistasis and the Evolutionary Process

Author : Jason B. Wolf
Publisher : Oxford University Press, USA
ISBN 13 : 9780195128062
Total Pages : 348 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Epistasis and the Evolutionary Process by : Jason B. Wolf

Download or read book Epistasis and the Evolutionary Process written by Jason B. Wolf and published by Oxford University Press, USA. This book was released on 2000 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last two decades, research into epistasis has seen explosive growth and has moved the focus of research in evolutionary genetics from a traditional additive approach. We now know the effects of genes are rarely independent, and to reach a fuller understanding of the process of evolution we need to look at gene interactions as well as gene-environment interactions. This book is an overview of non-additive evolutionary genetics, integrating all work to date on all levels of evolutionary investigation of the importance of epistasis in the evolutionary process in general. It includes a historical perspective on this emerging field, in-depth discussion of terminology, discussions of the effects of epistasis at several different levels of biological organization and combinations of theoretical and experimental approaches to analysis.

Epistasis and the Evolutionary Process

Author : Alex Thomas Kalinka
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (66 download)

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Book Synopsis Epistasis and the Evolutionary Process by : Alex Thomas Kalinka

Download or read book Epistasis and the Evolutionary Process written by Alex Thomas Kalinka and published by . This book was released on 2006 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Epistasis and the Evolutionary Process

Author : Alex Thomas Kalinka
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (66 download)

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Book Synopsis Epistasis and the Evolutionary Process by : Alex Thomas Kalinka

Download or read book Epistasis and the Evolutionary Process written by Alex Thomas Kalinka and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pillars of Evolution

Author : Douglas W. Morris
Publisher : Oxford University Press
ISBN 13 : 0198568797
Total Pages : 281 pages
Book Rating : 4.1/5 (985 download)

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Book Synopsis Pillars of Evolution by : Douglas W. Morris

Download or read book Pillars of Evolution written by Douglas W. Morris and published by Oxford University Press. This book was released on 2011-07-14 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a perspective on adaptive evolution.

Microevolution Rate, Pattern, Process

Author : Andrew P. Hendry
Publisher : Springer Science & Business Media
ISBN 13 : 9401005850
Total Pages : 528 pages
Book Rating : 4.4/5 (1 download)

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Book Synopsis Microevolution Rate, Pattern, Process by : Andrew P. Hendry

Download or read book Microevolution Rate, Pattern, Process written by Andrew P. Hendry and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: From guppies to Galapagos finches and from adaptive landscapes to haldanes, this compilation of contributed works provides reviews, perspectives, theoretical models, statistical developments, and empirical demonstrations exploring the tempo and mode of microevolution on contemporary to geological time scales. New developments, and reviews, of classic and novel empirical systems demonstrate the strength and diversity of evolutionary processes producing biodiversity within species. Perspectives and theoretical insights expand these empirical observations to explore patterns and mechanisms of microevolution, methods for its quantification, and implications for the evolution of biodiversity on other scales. This diverse assemblage of manuscripts is aimed at professionals, graduate students, and advanced undergraduates who desire a timely synthesis of current knowledge, an illustration of exciting new directions, and a springboard for future investigations in the study of microevolution in the wild.

Evolutionary Genetics

Author : Charles W. Fox
Publisher : Oxford University Press
ISBN 13 : 9780199775040
Total Pages : 618 pages
Book Rating : 4.7/5 (75 download)

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Book Synopsis Evolutionary Genetics by : Charles W. Fox

Download or read book Evolutionary Genetics written by Charles W. Fox and published by Oxford University Press. This book was released on 2006-04-27 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Charles Fox and Jason Wolf have brought together leading researchers to produce a cutting-edge primer introducing readers to the major concepts in modern evolutionary genetics. This book spans the continuum of scale, from studies of DNA sequence evolution through proteins and development to multivariate phenotypic evolution, and the continuum of time, from ancient events that lead to current species diversity to the rapid evolution seen over relatively short time scales in experimental evolution studies. Chapters are accessible to an audience lacking extensive background in evolutionaryy genetics but also current and in-depth enough to be of value to established researchers in evolution biology.

On the Prevalence and Role of Epistasis in Shaping Fitness Within and Between Populations

Author : Onuralp Söylemez
Publisher :
ISBN 13 :
Total Pages : 144 pages
Book Rating : 4.:/5 (112 download)

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Book Synopsis On the Prevalence and Role of Epistasis in Shaping Fitness Within and Between Populations by : Onuralp Söylemez

Download or read book On the Prevalence and Role of Epistasis in Shaping Fitness Within and Between Populations written by Onuralp Söylemez and published by . This book was released on 2015 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: The role of epistasis – inter-dependent contributions of alleles to fitness – in shaping genetic variation within and between populations is an important question in evolutionary biology with significant implications for our understanding of the factors contributing to phenotypic variation. While epistasis has been shown to play an important role in evolutionary processes such as speciation and adaptive evolution, many aspects of this role remains poorly understood. In particular, there is much debate on whether observing prevalent epistasis in evolution can be taken as evidence for functional epistasis that is relevant to selectable variation. Here, we studied the nature of epistasis in protein evolution, and found a high prevalence of epistatic interactions between amino acid sites in the human genome. We showed that these interactions can help improve accuracy of predicting the impact of genetic variation on the protein structure and function. We also showed that hypothesis-driven search for epistasis in natural populations can detect genomic signatures of epistasis in humans.

Information and Meaning in Evolutionary Processes

Author : William F. Harms
Publisher : Cambridge University Press
ISBN 13 : 1139451626
Total Pages : 282 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Information and Meaning in Evolutionary Processes by : William F. Harms

Download or read book Information and Meaning in Evolutionary Processes written by William F. Harms and published by Cambridge University Press. This book was released on 2004-04-26 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is intended to help transform epistemology - the traditional study of knowledge - into a rigorous discipline by removing conceptual roadblocks and developing formal tools required for a fully naturalized epistemology. The evolutionary approach which Harms favours begins with the common observation that if our senses and reasoning were not reliable, then natural selection would have eliminated them long ago. The challenge for some time has been how to transform these informal musings about evolutionary epistemology into a rigorous theoretical discipline capable of complementing current scientific studies of the evolution of cognition with a philosophically defensible account of meaning and justification.

The Basics of Selection

Author : Graham Bell
Publisher : Springer Science & Business Media
ISBN 13 : 146155991X
Total Pages : 397 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis The Basics of Selection by : Graham Bell

Download or read book The Basics of Selection written by Graham Bell and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new textbook for students taking courses in evolution is addressed to one of the most difficult questions evolutionary biology, that of selection. Covering both artificial and natural selection, the author has written a short, readable text that will appeal to students and professionals alike. how the nature of the process determines the nature of evolutionary change.

The Princeton Guide to Evolution

Author : David A. Baum
Publisher : Princeton University Press
ISBN 13 : 1400848067
Total Pages : 888 pages
Book Rating : 4.4/5 (8 download)

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Book Synopsis The Princeton Guide to Evolution by : David A. Baum

Download or read book The Princeton Guide to Evolution written by David A. Baum and published by Princeton University Press. This book was released on 2013-11-04 with total page 888 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Princeton Guide to Evolution is a comprehensive, concise, and authoritative reference to the major subjects and key concepts in evolutionary biology, from genes to mass extinctions. Edited by a distinguished team of evolutionary biologists, with contributions from leading researchers, the guide contains some 100 clear, accurate, and up-to-date articles on the most important topics in seven major areas: phylogenetics and the history of life; selection and adaptation; evolutionary processes; genes, genomes, and phenotypes; speciation and macroevolution; evolution of behavior, society, and humans; and evolution and modern society. Complete with more than 100 illustrations (including eight pages in color), glossaries of key terms, suggestions for further reading on each topic, and an index, this is an essential volume for undergraduate and graduate students, scientists in related fields, and anyone else with a serious interest in evolution. Explains key topics in some 100 concise and authoritative articles written by a team of leading evolutionary biologists Contains more than 100 illustrations, including eight pages in color Each article includes an outline, glossary, bibliography, and cross-references Covers phylogenetics and the history of life; selection and adaptation; evolutionary processes; genes, genomes, and phenotypes; speciation and macroevolution; evolution of behavior, society, and humans; and evolution and modern society

Mutation and Evolution

Author : Ronny C. Woodruff
Publisher : Springer Science & Business Media
ISBN 13 : 9401152101
Total Pages : 561 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Mutation and Evolution by : Ronny C. Woodruff

Download or read book Mutation and Evolution written by Ronny C. Woodruff and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 561 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although debated since the time of Darwin, the evolutionary role of mutation is still controversial. In over 40 chapters from leading authorities in mutation and evolutionary biology, this book takes a new look at both the theoretical and experimental measurement and significance of new mutation. Deleterious, nearly neutral, beneficial, and polygenic mutations are considered in their effects on fitness, life history traits, and the composition of the gene pool. Mutation is a phenomenon that draws attention from many different disciplines. Thus, the extensive reviews of the literature will be valuable both to established researchers and to those just beginning to study this field. Through up-to-date reviews, the authors provide an insightful overview of each topic and then share their newest ideas and explore controversial aspects of mutation and the evolutionary process. From topics like gonadal mosaicism and mutation clusters to adaptive mutagenesis, mutation in cell organelles, and the level and distribution of DNA molecular changes, the foundation is set for continuing the debate about the role of mutation, fitness, and adaptability. It is a debate that will have profound consequences for our understanding of evolution.

Experimental Evolution

Author : Theodore Garland
Publisher : Univ of California Press
ISBN 13 : 052094447X
Total Pages : 750 pages
Book Rating : 4.5/5 (29 download)

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Book Synopsis Experimental Evolution by : Theodore Garland

Download or read book Experimental Evolution written by Theodore Garland and published by Univ of California Press. This book was released on 2009-12-03 with total page 750 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experimental approaches to evolution provide indisputable evidence of evolution by directly observing the process at work. Experimental evolution deliberately duplicates evolutionary processes—forcing life histories to evolve, producing adaptations to stressful environmental conditions, and generating lineage splitting to create incipient species. This unique volume summarizes studies in experimental evolution, outlining current techniques and applications, and presenting the field’s full range of research—from selection in the laboratory to the manipulation of populations in the wild. It provides work on such key biological problems as the evolution of Darwinian fitness, sexual reproduction, life history, athletic performance, and learning.

Environmental Epigenetics

Author : L. Joseph Su
Publisher : Springer
ISBN 13 : 1447166787
Total Pages : 327 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Environmental Epigenetics by : L. Joseph Su

Download or read book Environmental Epigenetics written by L. Joseph Su and published by Springer. This book was released on 2015-05-18 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.

Principles of Biology

Author : Lisa Bartee
Publisher :
ISBN 13 : 9781636350417
Total Pages : pages
Book Rating : 4.3/5 (54 download)

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Book Synopsis Principles of Biology by : Lisa Bartee

Download or read book Principles of Biology written by Lisa Bartee and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Principles of Biology sequence (BI 211, 212 and 213) introduces biology as a scientific discipline for students planning to major in biology and other science disciplines. Laboratories and classroom activities introduce techniques used to study biological processes and provide opportunities for students to develop their ability to conduct research.

Epistasis

Author : Ka-Chun Wong
Publisher :
ISBN 13 : 9781071609477
Total Pages : 402 pages
Book Rating : 4.6/5 (94 download)

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Book Synopsis Epistasis by : Ka-Chun Wong

Download or read book Epistasis written by Ka-Chun Wong and published by . This book was released on 2021 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Crumbling Genome

Author : Alexey S. Kondrashov
Publisher : John Wiley & Sons
ISBN 13 : 1118952111
Total Pages : 309 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis Crumbling Genome by : Alexey S. Kondrashov

Download or read book Crumbling Genome written by Alexey S. Kondrashov and published by John Wiley & Sons. This book was released on 2017-07-12 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thought-provoking exploration of deleterious mutations in the human genome and their effects on human health and wellbeing Despite all of the elaborate mechanisms that a cell employs to handle its DNA with the utmost care, a newborn human carries about 100 new mutations, originated in their parents, about 10 of which are deleterious. A mutation replacing just one of the more than three billion nucleotides in the human genome may lead to synthesis of a dysfunctional protein, and this can be inconsistent with life or cause a tragic disease. Several percent of even young people suffer from diseases that are caused, exclusively or primarily, by pre ]existing and new mutations in their genomes, including both a wide variety of genetically simple Mendelian diseases and diverse complex diseases such as birth anomalies, diabetes, and schizophrenia. Milder, but still substantial, negative effects of mutations are even more pervasive. As of now, we possess no means of reducing the rate at which mutations appear spontaneously. However, the recent flood of genomic data made possible by next-generation methods of DNA sequencing, enabled scientists to explore the impacts of deleterious mutations on humans with previously unattainable precision and begin to develop approaches to managing them. Written by a leading researcher in the field of evolutionary genetics, Crumbling Genome reviews the current state of knowledge about deleterious mutations and their effects on humans for those in the biological sciences and medicine, as well as for readers with only a general scientific literacy and an interest in human genetics. Provides an extensive introduction to the fundamentals of evolutionary genetics with an emphasis on mutation and selection Discusses the effects of pre-existing and new mutations on human genotypes and phenotypes Provides a comprehensive review of the current state of knowledge in the field and considers crucial unsolved problems Explores key ethical, scientific, and social issues likely to become relevant in the near future as the modification of human germline genotypes becomes technically feasible Crumbling Genome is must-reading for students and professionals in human genetics, genomics, bioinformatics, evolutionary biology, and biological anthropology. It is certain to have great appeal among all those with an interest in the links between genetics and evolution and how they are likely to influence the future of human health, medicine, and society.

Protein Physics

Author : Alexei V. Finkelstein
Publisher : Elsevier
ISBN 13 : 0081012365
Total Pages : 530 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Protein Physics by : Alexei V. Finkelstein

Download or read book Protein Physics written by Alexei V. Finkelstein and published by Elsevier. This book was released on 2016-06-22 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein Physics: A Course of Lectures covers the most general problems of protein structure, folding and function. It describes key experimental facts and introduces concepts and theories, dealing with fibrous, membrane, and water-soluble globular proteins, in both their native and denatured states. The book systematically summarizes and presents the results of several decades of worldwide fundamental research on protein physics, structure, and folding, describing many physical models that help readers make estimates and predictions of physical processes that occur in proteins. New to this revised edition is the inclusion of novel information on amyloid aggregation, natively disordered proteins, protein folding in vivo, protein motors, misfolding, chameleon proteins, advances in protein engineering & design, and advances in the modeling of protein folding. Further, the book provides problems with solutions, many new and updated references, and physical and mathematical appendices. In addition, new figures (including stereo drawings, with a special appendix showing how to use them) are added, making this an ideal resource for graduate and advanced undergraduate students and researchers in academia in the fields of biophysics, physics, biochemistry, biologists, biotechnology, and chemistry. Fully revised and expanded new edition based on the latest research developments in protein physics Written by the world's top expert in the field Deals with fibrous, membrane, and water-soluble globular proteins, in both their native and denatured states Summarizes, in a systematic form, the results of several decades of worldwide fundamental research on protein physics and their structure and folding Examines experimental data on protein structure in the post-genome era