Energy Balance And Hematologic Malignancies

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Energy Balance and Hematologic Malignancies

Author : Steven D Mittelman
Publisher : Springer Science & Business Media
ISBN 13 : 146142402X
Total Pages : 190 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Energy Balance and Hematologic Malignancies by : Steven D Mittelman

Download or read book Energy Balance and Hematologic Malignancies written by Steven D Mittelman and published by Springer Science & Business Media. This book was released on 2012-02-28 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: The obesity pandemic continues to increase on a world-wide basis with over 70% of the United States population being either overweight or obese. Hematologic malignancies have recently been identified among the obesity associated malignancies spanning the lifespan from childhood to the elderly and include leukemia, myeloma, lymphoma and others. In addition to the etiologic association between obesity and hematologic malignancies, the presence of obesity has profound effects on therapy by impacting pharmacokinetics of chemotherapeutic agents, dose, adipocyte metabolism and drug distribution. These may be particularly important in hematopoietic stem cell transplantation. Another important aspect of the association of obesity with hematologic malignancies is the increased incidence of obesity in children who successfully complete therapy for acute lymphoblastic leukemia. This and other observations indicate important relations between the hematopoietic systems and fat metabolism. This volume on Energy Balance in Hematologic Malignancies will provide an important volume in this series and a basis for better understanding etiology, mechanisms, therapeutics implications and experimental approaches. This volume of energy balance and cancer will focus on the relation of obesity to hematologic malignancies, the epidemiology, potential mechanisms, and thereapeutic considerations including effects on pharmacologic and physical approaches as well as the delayed effects of therapy on energy balance.

Impact of Energy Balance on Cancer Disparities

Author : Deborah J. Bowen
Publisher : Springer
ISBN 13 : 3319061038
Total Pages : 316 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Impact of Energy Balance on Cancer Disparities by : Deborah J. Bowen

Download or read book Impact of Energy Balance on Cancer Disparities written by Deborah J. Bowen and published by Springer. This book was released on 2014-07-28 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume reviews disparities in cancer genetics, etiology, treatment and survivorship that are associated with differences in energy balance and how those differences and disparities may be affected by geography, socioeconomic status, ethnicity, biology, behavior and others. State-of-the-art strategies are outlined to alter these problems at the individual, community and policy levels. The book provides a comprehensive assessment of the multiple contributions of disparities in energy balance and how they affect cancer. this volume should constitute a valuable resource to disparity focused investigators at all levels and serves an important guide to professionals that deal with these issues, especially those who determine and implement policy.

Murine Models, Energy Balance, and Cancer

Author : Nathan A. Berger
Publisher : Springer
ISBN 13 : 3319167332
Total Pages : 302 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Murine Models, Energy Balance, and Cancer by : Nathan A. Berger

Download or read book Murine Models, Energy Balance, and Cancer written by Nathan A. Berger and published by Springer. This book was released on 2015-06-19 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a transdisciplinary and translational review of many of the leading murine models used to study the mechanisms, mediators and biomarkers linking energy balance to cancer. It provides a review of murine models that should be of interest to basic, clinical and applied research investigators as well as nutrition scientists and students that work in cancer prevention, cancer control and treatment. The worldwide obesity pandemic has been extensively studied by epidemiologic and observational studies and even, in some cases, by randomized controlled trials. However, the development and control of obesity, its comorbidities and its impact on cancer usually occurs over such long periods that it is difficult, if not impossible to conduct randomized controlled trials in humans to investigate environmental contributions to obesity, energy balance and their impact on cancer. In contrast, model organisms, especially mice and rats, provide valuable assets for performing these studies under rigorously controlled conditions and in sufficient numbers to provide statistically significant results. In this volume, many of the leading and new murine models used to study the mechanisms and mediators linking cancer with obesity, sleep, exercise, their modification by environment and how they may continue to be used to further elucidate these relations as well as to explore preclinical aspects of prevention and/or therapeutic intervention are considered. This volume provides an important compilation and analysis of major experimental systems and principles for further preclinical research with translational impact on energy balance and cancer.

Exercise, Energy Balance, and Cancer

Author : Cornelia M. Ulrich
Publisher : Springer Science & Business Media
ISBN 13 : 1461444934
Total Pages : 240 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Exercise, Energy Balance, and Cancer by : Cornelia M. Ulrich

Download or read book Exercise, Energy Balance, and Cancer written by Cornelia M. Ulrich and published by Springer Science & Business Media. This book was released on 2012-10-10 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: While it is well established that the worldwide pandemic of overweight and obesity has profound effects on promoting cancer, it is now recognized that an alternative aspect of energy balance, namely physical activity and exercise have significant beneficial effects on all aspects of cancer across the spectrum from prevention through treatment and extending through survivorship. Moreover, salutary effects of physical activity and exercise extend across the age span from youth to old age and occur at all stages of cancer extending into palliative care. While the effect of physical activity and exercise on cancer may be partially mediated through obesity control, it is clear that considerable research is required and is ongoing at both the molecular and clinical levels to better understand the associated mechanisms and to develop optimal exercise strategies. This volume will contain chapters on the effect of exercise on biological pathways in tumor growth, state art exercise strategies and cutting edge research focused on different cancers and patient groups. It will provide an important volume in this series on energy balance and cancer and a basis for ongoing research, experimental approaches and application of evidence based practices to clinical care for patients with cancer.

Holland-Frei Cancer Medicine

Author : Robert C. Bast, Jr.
Publisher : John Wiley & Sons
ISBN 13 : 111900084X
Total Pages : 2004 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Holland-Frei Cancer Medicine by : Robert C. Bast, Jr.

Download or read book Holland-Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2004 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Hematology

Author : Ronald Hoffman
Publisher : Elsevier Health Sciences
ISBN 13 : 1437729282
Total Pages : 2789 pages
Book Rating : 4.4/5 (377 download)

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Book Synopsis Hematology by : Ronald Hoffman

Download or read book Hematology written by Ronald Hoffman and published by Elsevier Health Sciences. This book was released on 2013-01-01 with total page 2789 pages. Available in PDF, EPUB and Kindle. Book excerpt: This leading text reflects both the new direction and explosive growth of the field of hematology. Edited and written by practitioners who are the leaders in the field, the book covers basic scientific foundations of hematology while focusing on its clinical aspects. This edition has been thoroughly updated and includes ten new chapters on cellular biology, haploidentical transplantation, hematologic manifestations of parasitic diseases, and more. The table of contents itself has been thoroughly revised to reflect the rapidly changing nature of the molecular and cellular areas of the specialty. Over 1,000 vivid images, now all presented in full color for the first time, include a collection of detailed photomicrographs in every chapter, selected by a hematopathology image consultant. What's more, this Expert Consult Premium Edition includes access to the complete contents of the book online, fully searchable and updated quarterly by Dr. Hoffman himself. - Publisher.

Adipocytokines, Energy Balance, and Cancer

Author : Ofer Reizes
Publisher : Springer
ISBN 13 : 3319416774
Total Pages : 306 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Adipocytokines, Energy Balance, and Cancer by : Ofer Reizes

Download or read book Adipocytokines, Energy Balance, and Cancer written by Ofer Reizes and published by Springer. This book was released on 2016-10-31 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adipocytokines provide the circuitry by which adipose tissue communicates among its component cells which include adipocytes, stromal cells, immune cells and vascular elements, with adipose tissue depots in other locations throughout the body and with other tissues in order to regulate physiologic processes of energy intake, utilization, and distribution. Since disturbances, both qualitative and quantitative, in adipocytokine function contribute significantly to many of the comorbidities associated with obesity, including diabetes, cardiovascular disease and cancer, this volume, which discusses most of the major adipocytokines independently and collectively and their roles in normal and pathologic processes, should be useful to all individuals seeking a deeper understanding of these processes. Moreover, it provides a valuable complement to the series on Energy Balance and Cancer, in which each volume is focused on a specific aspect of this process, which now constitutes an expanding problem as the obesity pandemic continues and more of the population reaches the age where cancer is most prevalent. This volume should provide a valuable resource to all clinicians and scientists engaged in caring for susceptible patients and in exploring the relation between energy balance and cancer as well as an important platform to providing the background for research development.

Strategies for Team Science Success

Author : Kara L. Hall
Publisher : Springer Nature
ISBN 13 : 303020992X
Total Pages : 633 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Strategies for Team Science Success by : Kara L. Hall

Download or read book Strategies for Team Science Success written by Kara L. Hall and published by Springer Nature. This book was released on 2019-11-13 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: Collaborations that integrate diverse perspectives are critical to addressing many of our complex scientific and societal problems. Yet those engaged in cross-disciplinary team science often face institutional barriers and collaborative challenges. Strategies for Team Science Success offers readers a comprehensive set of actionable strategies for reducing barriers and overcoming challenges and includes practical guidance for how to implement effective team science practices. More than 100 experts--including scientists, administrators, and funders from a wide range of disciplines and professions-- explain evidence-based principles, highlight state-of the-art strategies, tools, and resources, and share first-person accounts of how they’ve applied them in their own successful team science initiatives. While many examples draw from cross-disciplinary team science initiatives in the health domain, the handbook is designed to be useful across all areas of science. Strategies for Team Science Success will inspire and enable readers to embrace cross-disciplinary team science, by articulating its value for accelerating scientific progress, and by providing practical strategies for success. Scientists, administrators, funders, and others engaged in team science will also leave equipped to develop new policies and practices needed to keep pace in our rapidly changing scientific landscape. Scholars across the Science of Team Science (SciTS), management, organizational, behavioral and social sciences, public health, philosophy, and information technology, among other areas of scholarship, will find inspiration for new research directions to continue advancing cross-disciplinary team science.

Cancer and Energy Balance, Epidemiology and Overview

Author : Nathan A. Berger
Publisher : Springer Science & Business Media
ISBN 13 : 1441955151
Total Pages : 316 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Cancer and Energy Balance, Epidemiology and Overview by : Nathan A. Berger

Download or read book Cancer and Energy Balance, Epidemiology and Overview written by Nathan A. Berger and published by Springer Science & Business Media. This book was released on 2010-06-16 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Energy Balance and Cancer, Epidemiology and Overview is the first in a series of monographs to address the multiple facets of the world wide pandemic of overweight and obesity and its relation to cancer. This volume, authored by leading experts in their perspective fields, provides a broad and comprehensive overview of the problem from the epidemiologic viewpoint with focus on both general and special populations as well as a description of potential molecular mechanisms and reviews of the latest studies of factors impacting the association of energy balance and cancer including the effects of genetics, caloric restriction, exercise, behavior and the built environment. The collected chapters and the authors contributing to this initial volume represent a transdisciplinary approach to analyze and develop novel approaches to understand and solve what, up to now, is a globally refractory problem. The book is written to be understandable and informative to individuals from all concerned disciplines. It should serve to orient students, investigators, nutritionists, public health officials, community planners, clinicians and policy makers to the extent of the problem, its multiple dimensions and potential approaches for research and corrective interventions.

Hematology: Diagnosis and Treatment E-Book

Author : Ronald Hoffman
Publisher : Elsevier Health Sciences
ISBN 13 : 1455776882
Total Pages : 2789 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Hematology: Diagnosis and Treatment E-Book by : Ronald Hoffman

Download or read book Hematology: Diagnosis and Treatment E-Book written by Ronald Hoffman and published by Elsevier Health Sciences. This book was released on 2013-03-29 with total page 2789 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Hematology: Diagnosis and Treatment eBook is the ideal mobile resource in hematology! It distills the most essential, practical information from Hematology: Basic Principles and Practice, 6th Edition - the comprehensive masterwork by Drs. Hoffman, Benz, Silberstein, Heslop, Weitz, and Anastasi - into a concise, clinically focused resource that's optimized for reference on any e-reader. Focusing on the dependable, state-of-the-art clinical strategies you need to optimally diagnose and manage the full range of blood diseases and disorders, this eBook is a must-have for every hematologist's mobile device! Apply the latest know-how on heparin-induced thrombocytopenia, stroke, acute coronary syndromes, hematologic manifestations of liver disease, hematologic manifestations of cancer, hematology in aging, and many other hot topics. Get quick, focused answers on the diagnosis and management of blood diseases - in a portable digital format that you can carry and consult anytime, anywhere. View abundant images that mirror the pivotal role hematopathology plays in the practice of modern hematology. Count on all the authority that has made Hematology: Basic Principles and Practice, 6th Edition, edited by Drs. Hoffman, Benz, Silberstein, Heslop, Weitz, and Anastasi, the go-to clinical reference for hematologists worldwide. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices.

The Heterogeneity of Cancer Metabolism

Author : Anne Le
Publisher : Springer
ISBN 13 : 331977736X
Total Pages : 186 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis The Heterogeneity of Cancer Metabolism by : Anne Le

Download or read book The Heterogeneity of Cancer Metabolism written by Anne Le and published by Springer. This book was released on 2018-06-26 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.

Hematological Malignancies in Children, Adolescents and Young Adults

Author : Mitchell S. Cairo
Publisher : World Scientific
ISBN 13 : 981429960X
Total Pages : 601 pages
Book Rating : 4.8/5 (142 download)

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Book Synopsis Hematological Malignancies in Children, Adolescents and Young Adults by : Mitchell S. Cairo

Download or read book Hematological Malignancies in Children, Adolescents and Young Adults written by Mitchell S. Cairo and published by World Scientific. This book was released on 2012 with total page 601 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bringing together intellectual and scientific experts from pediatrics, adolescent medicine, general medicine, pathology, biology, nursing and psychology, this book is the first of its kind to cover the topics of leukemias and lymphomas in young patients ranging from infants to young adults. The content is organized and subdivided into four major sections -- under the main headings of General Considerations, Pathobiology, Clinical Manifestations and Treatment, and Supportive Care and Complications -- for ease of reference to readers. Hematological Malignancies in Children, Adolescents and Young Adults presents a comprehensive multidisciplinary review of the field of hematological malignancies and brings forth illuminating perspectives from an internationally recognized group of leading authorities in the field.

Demystifying Drug Dosing in Obese Patients

Author : Brandon R Shank
Publisher : ASHP
ISBN 13 : 1585284831
Total Pages : 346 pages
Book Rating : 4.5/5 (852 download)

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Book Synopsis Demystifying Drug Dosing in Obese Patients by : Brandon R Shank

Download or read book Demystifying Drug Dosing in Obese Patients written by Brandon R Shank and published by ASHP. This book was released on 2016-01-04 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: With Demystifying Drug Dosing in Obese Patients, that resource you need is here, delivering: Fully-referenced dosing recommendations for specific drugs Dedicated chapters on antimicrobial dosing, anticoagulants and antiplatelets, antiepileptics, analgesics, antineoplastic medicines, and more Guidance on immunosuppression and medication absorption in bariatric surgery Tips for adult, pediatric, ambulatory, acute, and critical care Pharmacokinetic parameters in obese patients

Physical Activity and Cancer

Author : Kerry S. Courneya
Publisher : Springer Science & Business Media
ISBN 13 : 3642042317
Total Pages : 389 pages
Book Rating : 4.6/5 (42 download)

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Book Synopsis Physical Activity and Cancer by : Kerry S. Courneya

Download or read book Physical Activity and Cancer written by Kerry S. Courneya and published by Springer Science & Business Media. This book was released on 2010-11-26 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores in depth the relation between physical activity and cancer control, including primary prevention, coping with treatments, recovery after treatments, long-term survivorship, secondary prevention, and survival. The first part of the book presents the most recent research on the impact of physical activity in preventing a range of cancers. In the second part, the association between physical activity and cancer survivorship is addressed. The effects of physical activity on supportive care endpoints (e.g., quality of life, fatigue, physical functioning) and disease endpoints (e.g., biomarkers, recurrence, survival) are carefully analyzed. In addition, the determinants of physical activity in cancer survivors are discussed, and behavior change strategies for increasing physical activity in cancer survivors are appraised. The final part of the book is devoted to special topics, including the relation of physical activity to pediatric cancer survivorship and to palliative cancer care.

Colorectal Cancer, An Issue of Hematology/Oncology Clinics

Author : Leonard B. Saltz
Publisher : Elsevier Health Sciences
ISBN 13 : 0323326536
Total Pages : 166 pages
Book Rating : 4.3/5 (233 download)

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Book Synopsis Colorectal Cancer, An Issue of Hematology/Oncology Clinics by : Leonard B. Saltz

Download or read book Colorectal Cancer, An Issue of Hematology/Oncology Clinics written by Leonard B. Saltz and published by Elsevier Health Sciences. This book was released on 2014-12-10 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Hematology/Oncology Clinics of North America, devoted to Colorectal Cancer, is edited by Dr. Leonard B. Saltz. Articles in this issue include: Diet and Lifestyle Influences on Colorectal Cancer; Diagnosis and Management of Germline and Somatic Mutations in Mismatch Repair-deficient Colorectal Cancer; Adjuvant Chemotherapy in Stage II, III, and Resected Stage IV Colon Cancer; Predictive and Prognostic Markers in the Treatment of Colorectal Cancer; Surgical Management of Hepatic Metastases of Colorectal Cancer; Combination Therapies in Colorectal Cancer Treatment; A Critical Look at Management of Peritoneal Metastases of Colorectal Cancer; Non-surgical Management of Rectal Cancer; and Ablative Therapies for Metastatic Colorectal Cancer.

Targeting the Microenvironment Niche in Hematologic Malignancies

Author : Cirino Botta
Publisher : Frontiers Media SA
ISBN 13 : 2889742679
Total Pages : 193 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Targeting the Microenvironment Niche in Hematologic Malignancies by : Cirino Botta

Download or read book Targeting the Microenvironment Niche in Hematologic Malignancies written by Cirino Botta and published by Frontiers Media SA. This book was released on 2022-02-02 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Childhood Acute Lymphoblastic Leukemia

Author : Ajay Vora
Publisher : Springer
ISBN 13 : 3319397087
Total Pages : 345 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Childhood Acute Lymphoblastic Leukemia by : Ajay Vora

Download or read book Childhood Acute Lymphoblastic Leukemia written by Ajay Vora and published by Springer. This book was released on 2017-04-21 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.