Endothelium and Cardiovascular Diseases

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Author :
Publisher : Academic Press
ISBN 13 : 0128125519
Total Pages : 760 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Endothelium and Cardiovascular Diseases by : Protasio L. Da Luz

Download or read book Endothelium and Cardiovascular Diseases written by Protasio L. Da Luz and published by Academic Press. This book was released on 2018-02-03 with total page 760 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endothelium and Cardiovascular Diseases: Vascular Biology and Clinical Syndromes provides an in-depth examination of the role of endothelium and endothelial dysfunction in normal vascular function, and in a broad spectrum of clinical syndromes, from atherosclerosis, to cognitive disturbances and eclampsia. The endothelium is a major participant in the pathophysiology of diseases, such as atherosclerosis, diabetes and hypertension, and these entities are responsible for the largest part of cardiovascular mortality and morbidly. Over the last decade major new discoveries and concepts involving the endothelium have come to light. This important reference collects this data in an easy to reference resource. Written by known experts, and covering all aspects of endothelial function in health and disease, this reference represents an assembly of recent knowledge that is essential to both basic investigators and clinicians. - Provides a complete overview of endothelial function in health and diseases, along with an assessment of new information - Includes coverage of groundbreaking areas, including the artificial LDL particle, the development of a new anti-erectile dysfunction agent, a vaccine for atherosclerosis, coronary calcification associated with red wine, and the interplay of endoplasmic reticulum/oxidative stress - Explores the genetic features of endothelium and the interaction between basic knowledge and clinical syndromes

Endothelium and Cardiovascular Diseases

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Author :
Publisher : Academic Press
ISBN 13 : 9780128123485
Total Pages : 0 pages
Book Rating : 4.1/5 (234 download)

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Book Synopsis Endothelium and Cardiovascular Diseases by : Protasio Lemos Da Luz

Download or read book Endothelium and Cardiovascular Diseases written by Protasio Lemos Da Luz and published by Academic Press. This book was released on 2018-01-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endothelium and Cardiovascular Diseases: Vascular Biology and Clinical Syndromes provides an in-depth examination of the role of endothelium and endothelial dysfunction in normal vascular function, and in a broad spectrum of clinical syndromes, from atherosclerosis, to cognitive disturbances and eclampsia. The endothelium is a major participant in the pathophysiology of diseases, such as atherosclerosis, diabetes and hypertension, and these entities are responsible for the largest part of cardiovascular mortality and morbidly. Over the last decade major new discoveries and concepts involving the endothelium have come to light. This important reference collects this data in an easy to reference resource. Written by known experts, and covering all aspects of endothelial function in health and disease, this reference represents an assembly of recent knowledge that is essential to both basic investigators and clinicians.

Endothelium and Cardiovascular Diseases

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Author :
Publisher : Academic Press
ISBN 13 : 044324037X
Total Pages : 0 pages
Book Rating : 4.4/5 (432 download)

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Book Synopsis Endothelium and Cardiovascular Diseases by : Protasio L. Da Luz

Download or read book Endothelium and Cardiovascular Diseases written by Protasio L. Da Luz and published by Academic Press. This book was released on 2025-06-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endothelium and Cardiovascular Diseases: Vascular Biology and Clinical Syndromes, Second Edition offers new discoveries in clinical settings, cellular, molecular, genetic, and epigenetic mechanisms which have led to novel understanding of the key role of endothelium in both cardiovascular and non-cardiovascular diseases. The innovations it presents have implications for both pathophysiological concepts and clinical decisions. Among other topics, cardiovascular and pulmonary medicine, immunity and inflammation, genetics and epigenetics, heart failure, renal disease, familial hypercholesterolemia, diabetes, and hypertension are discussed at length. Thus, readers will find relevant information from a wide array of fields in one volume, rather than scouring numerous sources. With 20 new chapters covering everything from endothelium transition to connective tissue disorders, this second edition of Endothelium and Cardiovascular Diseases: Vascular Biology and Clinical Syndromes is sure to be indispensable to anyone wishing to learn the importance of endothelium to every facet of health. - Examines the ways in which endothelium relates to almost every cardiovascular and systemic disease - Provides a critical, in depth, pathophysiological review of endothelium which cannot be found in any other single volume - Offers cutting-edge, critical knowledge for investigators and practioners alike; information which has evolved rapidly since the previous edition

The Endothelium

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Author :
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1615041230
Total Pages : 309 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis The Endothelium by : Michel Félétou

Download or read book The Endothelium written by Michel Félétou and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References

Mechanisms of Vascular Disease

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Author :
Publisher : University of Adelaide Press
ISBN 13 : 1922064009
Total Pages : 589 pages
Book Rating : 4.9/5 (22 download)

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Book Synopsis Mechanisms of Vascular Disease by : Robert Fitridge

Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Endothelial Dysfunction

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 1789842530
Total Pages : 432 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Endothelial Dysfunction by : Helena Lenasi

Download or read book Endothelial Dysfunction written by Helena Lenasi and published by BoD – Books on Demand. This book was released on 2018-10-24 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: The endothelium enables communication between blood and tissues and is actively involved in cardiovascular homeostasis. Endothelial dysfunction has been recognized as an early step in the development of cardiovascular diseases: respectively, endothelium represents a potential therapeutic niche with multiple targets. The purpose of the book is to point out some recent findings of endothelial physiology and pathophysiology emphasizing various aspects of endothelial dysfunction connected to the body's internal and external environment. While basic features of the endothelium are presented in an introductory chapter, the authors of the following 17 chapters have provided extensive insight into some selected topics of endothelial (dys)function. The book would hopefully be useful for anyone interested in recapitulating endothelial (patho)physiology and expanding knowledge of molecular mechanisms involved in endothelial dysfunction, relevant also for further clinical investigations.

How Tobacco Smoke Causes Disease

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Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis How Tobacco Smoke Causes Disease by : United States. Public Health Service. Office of the Surgeon General

Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Endothelial Dysfunction and Inflammation

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3034601689
Total Pages : 243 pages
Book Rating : 4.0/5 (346 download)

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Book Synopsis Endothelial Dysfunction and Inflammation by : Shauna Dauphinee

Download or read book Endothelial Dysfunction and Inflammation written by Shauna Dauphinee and published by Springer Science & Business Media. This book was released on 2010-09-24 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endothelial dysfunction is broadly defined as a disruption of the balance between vasoactive mediators and a propensity towards an inflammatory state. This volume provides an overview of the fields of endothelial dysfunction and inflammation through the discussion of topics ranging from the molecular biology of activated endothelial cells to the endothelium in inflammatory disease and therapeutic approaches targeting endothelial dysfunction. Topics include: Heterogeneity of the endothelium during inflammation, oxidative stress and endothelial dysfunction, biology and regulation of nitric oxide in inflammatory pathologies, endothelial dysfunction in inflammatory diseases, such as diabetes and atherosclerosis and Clinical methods used to assess endothelial function. This book brings together basic and clinical research to assist the reader in bridging connections from bench-to-bedside. Written by expert researchers in the fields of endothelial biology, inflammation research and clinical science, it serves as a useful reference for academic and industrial researchers, clinicians, and trainees in the medical profession.

Microcirculation

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Publisher : Springer
ISBN 13 : 9783030281984
Total Pages : 298 pages
Book Rating : 4.2/5 (819 download)

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Book Synopsis Microcirculation by : Maria Dorobantu

Download or read book Microcirculation written by Maria Dorobantu and published by Springer. This book was released on 2019-11-18 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive reference book of coronary microcirculation broadly covers theoretical aspects, clinical cases and therapeutic considerations from an innovative perspective. Topics covered include: ischemic heart disease, silent cerebral damage, heart failure, left ventricular hypertrophy arrhythmias, and cerebral and renal microcirculation. Microcirculation: From Bench to Bedside underlines the clinical importance of addressing coronary microcirculation with relevant clinical examples that are often encountered by practitioners. It therefore provides a critical resource on microcirculation for both specialist and non-specialist practitioners.

Manual of Neurosonology

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Publisher : Cambridge University Press
ISBN 13 : 1107659159
Total Pages : 333 pages
Book Rating : 4.1/5 (76 download)

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Book Synopsis Manual of Neurosonology by : László Csiba

Download or read book Manual of Neurosonology written by László Csiba and published by Cambridge University Press. This book was released on 2016-04-28 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurosonology is non-invasive, portable, and has excellent temporal resolution, making it a valuable and increasingly popular tool for the diagnosis and monitoring of neurological conditions when compared to other imaging techniques. This guide looks beyond the use of neurovascular ultrasound in stroke to encompass a wide range of other neurological diseases and emergencies. It offers a practical approach to the examination of patients, interpretation of ultrasound studies, and the application of neurosonology to the development of management and treatment strategies. Each chapter incorporates a thorough and clear procedural methodology alongside scanning tips for trainees; this step-by-step approach is further enhanced by example images and focused diagnostic questions. Authored and edited by international experts, this practical manual of neurosonology is an invaluable resource for neurologists, neurosurgeons, intensivists, radiologists, and ultrasonographers.

Pediatric Hypertension

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Publisher : Springer Science & Business Media
ISBN 13 : 1627034900
Total Pages : 597 pages
Book Rating : 4.6/5 (27 download)

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Book Synopsis Pediatric Hypertension by : Joseph Flynn

Download or read book Pediatric Hypertension written by Joseph Flynn and published by Springer Science & Business Media. This book was released on 2013-06-26 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of pediatric hypertension has undergone important changes in the time since the second edition of Pediatric Hypertension published. Much new information on hypertension in the young has become available. Previous chapters have been fully revised and new chapters have been added to cover important topics of recent interest such as consensus recommendations, the prevalence of hypertension in the young due to the obesity epidemic, studies of antihypertensive agents, and ambulatory blood pressure monitoring. Pediatric Hypertension, Third Edition is a comprehensive volume featuring 38 chapters covering the breadth of the current knowledge. It is divided into four sections: Regulation of Blood Pressure in Children; Assessment of Blood Pressure in Children: Measurement, Normative Data, Epidemiology; and Hypertension in Children: Predictors, Risk Factors, and Special Populations; Evaluation and Management of Pediatric Hypertension. Filled with the most up-to-date information, Pediatric Hypertension, Third Edition is an invaluable resource for clinicians and researchers interested in childhood hypertension.

Prevent and Reverse Heart Disease

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Author :
Publisher : Penguin
ISBN 13 : 1583333002
Total Pages : 329 pages
Book Rating : 4.5/5 (833 download)

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Book Synopsis Prevent and Reverse Heart Disease by : Caldwell B. Esselstyn Jr. M.D.

Download or read book Prevent and Reverse Heart Disease written by Caldwell B. Esselstyn Jr. M.D. and published by Penguin. This book was released on 2008-01-31 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: The New York Times bestselling guide to the lifesaving diet that can both prevent and help reverse the effects of heart disease Based on the groundbreaking results of his twenty-year nutritional study, Prevent and Reverse Heart Disease by Dr. Caldwell Esselstyn illustrates that a plant-based, oil-free diet can not only prevent the progression of heart disease but can also reverse its effects. Dr. Esselstyn is an internationally known surgeon, researcher and former clinician at the Cleveland Clinic and a featured expert in the acclaimed documentary Forks Over Knives. Prevent and Reverse Heart Disease has helped thousands across the country, and is the book behind Bill Clinton’s life-changing vegan diet. The proof lies in the incredible outcomes for patients who have followed Dr. Esselstyn's program, including a number of patients in his original study who had been told by their cardiologists that they had less than a year to live. Within months of starting the program, all Dr. Esselstyn’s patients began to improve dramatically, and twenty years later, they remain free of symptoms. Complete with more than 150 delicious recipes perfect for a plant-based diet, the national bestseller Prevent and Reverse Heart Disease explains the science behind the simple plan that has drastically changed the lives of heart disease patients forever. It will empower readers and give them the tools to take control of their heart health.

Endocardial Endothelium

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Author :
Publisher :
ISBN 13 :
Total Pages : 154 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Endocardial Endothelium by : Stanislas U. Sys

Download or read book Endocardial Endothelium written by Stanislas U. Sys and published by . This book was released on 1995 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: Places the discovery of the key role of cardiac endothelial cells in the control and modulation of heart performance in historical perspective, emphasizing the contributions of numerous investigators since 1986. Summarizes the major morphological, embryological, and comparative physiological features of the cells, and details the two main hypotheses for understanding the underlying mechanisms of the interaction between cardiac endothelial cells and cardiomyocytes. Includes bandw photos. Annotation copyright by Book News, Inc., Portland, OR

Oxidative Stress and Vascular Disease

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Publisher : Springer Science & Business Media
ISBN 13 : 9780792386780
Total Pages : 404 pages
Book Rating : 4.3/5 (867 download)

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Book Synopsis Oxidative Stress and Vascular Disease by : John F. Keaney Jr.

Download or read book Oxidative Stress and Vascular Disease written by John F. Keaney Jr. and published by Springer Science & Business Media. This book was released on 1999-12-31 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the major biomedical triumphs of the post-World War II era was the defmitive demonstration that hypercholesterolemia is a key causative factor in atherosclerosis; that hypercholesterolemia can be effectively treated; and that treatment significantly reduces not only coronary disease mortality but also all cause mortality. Treatment to lower plasma levels of cholesterol - primarily low density lipoprotein (LDL) cholesterol - is now accepted as best medical practice and both physicians and patients are being educated to take aggressive measures to lower LDL. We can confidently look forward to important decreases in the toll of coronary artery disease over the coming decades. However, there is still uncertainty as to the exact mechanisms by which elevated plasma cholesterol and LDL levels initiate and favor the progression of lesions. There is general consensus that one of the earliest responses to hypercholesterolemia is the adhesion of monocytes to aortic endothelial cells followed by their penetration into the subendothelial space, where they differentiate into macrophages. These cells, and also medial smooth muscle cells that have migrated into the subendothelial space, then become loaded with mUltiple, large droplets of cholesterol esters . . . the hallmark of the earliest visible atherosclerotic lesion, the so-called fatty streak. This lesion is the precursor of the more advanced lesions, both in animal models and in humans. Thus the centrality of hypercholesterolemia cannot be overstated. Still, the atherogenic process is complex and evolves over a long period of time.

Vascular Endothelium in Human Physiology and Pathophysiology

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Author :
Publisher : CRC Press
ISBN 13 : 0203304950
Total Pages : 302 pages
Book Rating : 4.2/5 (33 download)

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Book Synopsis Vascular Endothelium in Human Physiology and Pathophysiology by : Patrick J Vallance

Download or read book Vascular Endothelium in Human Physiology and Pathophysiology written by Patrick J Vallance and published by CRC Press. This book was released on 2003-09-02 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endothelial dysfunction is now regarded as an early marker of vascular disease and therefore an important target for therapeutic intervention and discovery of novel treatments. Ideal for both basic and clinical scientists, whether in industry or academia, and physicians, Vascular Endothelium in Human Physiology and Pathophysiology provides an up-to-date review of the vascular functions of the endothelium and its role in key areas of cardiovascular disease. It focuses on evidence from studies in humans.

Hemodynamics and Mechanobiology of Endothelium

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Author :
Publisher : World Scientific
ISBN 13 : 9814280410
Total Pages : 380 pages
Book Rating : 4.8/5 (142 download)

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Book Synopsis Hemodynamics and Mechanobiology of Endothelium by : Tzung K. Hsiai

Download or read book Hemodynamics and Mechanobiology of Endothelium written by Tzung K. Hsiai and published by World Scientific. This book was released on 2010 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book represents a paradigm shift from the traditional static model of investigation of oxidative biology to the dynamic model of vascular oxidative stress. The investigation of vascular biology and cardiovascular medicine is made possible by the use of tissue engineering, nanotechnology and stem cell research. This is the first textbook to target a wide readership from academia to industry and government agencies in the field of cardiovascular diseases.

PanVascular Medicine

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Publisher : Springer
ISBN 13 : 9783642370779
Total Pages : 5004 pages
Book Rating : 4.3/5 (77 download)

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Book Synopsis PanVascular Medicine by : Peter Lanzer

Download or read book PanVascular Medicine written by Peter Lanzer and published by Springer. This book was released on 2015-03-30 with total page 5004 pages. Available in PDF, EPUB and Kindle. Book excerpt: ​Vascular management and care has become a truly multidisciplinary enterprise as the number of specialists involved in the treatment of patients with vascular diseases has steadily increased. While in the past, treatments were delivered by individual specialists, in the twenty-first century a team approach is without doubt the most effective strategy. In order to promote professional excellence in this dynamic and rapidly evolving field, a shared knowledge base and interdisciplinary standards need to be established. Pan Vascular Medicine, 2nd edition has been designed to offer such an interdisciplinary platform, providing vascular specialists with state-of-the art descriptive and procedural knowledge. Basic science, diagnostics, and therapy are all comprehensively covered. In a series of succinct, clearly written chapters, renowned specialists introduce and comment on the current international guidelines and present up-to-date reviews of all aspects of vascular care.