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Author : Anna Healy
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (139 download)
Download or read book Enantioselective Synthesis of Beta-amino Acids for Inclusion Into Natural Products written by Anna Healy and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Eusebio Juaristi
Publisher : John Wiley & Sons
ISBN 13 : 0471698474
Total Pages : 658 pages
Book Rating : 4.4/5 (716 download)
Download or read book Enantioselective Synthesis of Beta-Amino Acids written by Eusebio Juaristi and published by John Wiley & Sons. This book was released on 2005-05-06 with total page 658 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers all facets of the synthesis of ß-amino acids As evidenced by an exponential increase in the literature published on the subject, interest in ß-amino acids has grown over the past several years. With major pharmaceutical applications, these amino acids are now studied across multiple lines of research, including combinatorial chemistry, medicinal chemistry, molecular design, proteomics, and others. This Second Edition of Enantioselective Synthesis of ß-Amino Acids updates reviews included in the First Edition while also covering new developments since its publication. The book presents detailed discussions of the most important methods for the synthesis of ß-amino acids. In most cases, the lead chemist who originally developed a method provides an authoritative description of it. In addition, Enantioselective Synthesis of ß-Amino Acids, Second Edition: * Features introductory overviews on the structural types of relevant ß-amino acid targets and salient ß-amino acids present in natural products * Dedicates several chapters to advances in the synthesis of oligomers from ß-amino acids * Includes general and practical procedures for the preparation of ß-amino acids in each chapter * Discusses the most important methods that have been recently developed for the asymmetric synthesis of cyclic and open-chain ß-amino acids * Includes a report on the preparation of libraries of enantiopure ß-amino acids using combinatorial approaches The only book of its kind available today, Enantioselective Synthesis of ß-Amino Acids, Second Edition offers upper-level students and professionals an essential resource for pharmaceutical development, medicinal chemistry, and biochemistry.
Author : Ashot S. Saghyan
Publisher : John Wiley & Sons
ISBN 13 : 3527804471
Total Pages : 450 pages
Book Rating : 4.5/5 (278 download)
Download or read book Asymmetric Synthesis of Non-Proteinogenic Amino Acids written by Ashot S. Saghyan and published by John Wiley & Sons. This book was released on 2016-09-23 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authored by two internationally recognized experts with an excellent track record, this much-needed reference summarizes latest research in the rapidly developing field of stereoselective synthesis of enantiomerically enriched amino acids, particularly of non-proteinogenic origin. It highlights several different catalytic and stoichiometric asymmetric methods for their synthesis and also provides information on origin, biological properties, different synthetic strategies and important applications in medicine and pharmacology. Essential reading for synthetic chemists working in the field of asymmetric synthesis, natural products and peptide synthesis, stereochemistry, medicinal chemistry, biochemistry, pharmacology, and biotechnology.
![Download Asymmetric Synthesis of [beta]-amino Acid Containing Natural Products PDF Online Free](https://books.google.com/books/content/images/frontcover/Wg6B0AEACAAJ?fife=w200-h370)
Author : Peter M. Kelly
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (592 download)
Download or read book Asymmetric Synthesis of [beta]-amino Acid Containing Natural Products written by Peter M. Kelly and published by . This book was released on 2004 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Eusebio Juaristi
Publisher : Wiley
ISBN 13 : 9780471186274
Total Pages : 0 pages
Book Rating : 4.1/5 (862 download)
Download or read book Enantioselective Synthesis of ß-Amino Acids written by Eusebio Juaristi and published by Wiley. This book was released on 1996-12-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an overview of the importance of ß-amino acids in pharmaceutical sciences, and discusses the most important methods that have been developed for the preparation of enantiomerically pure compounds. Each method is described by the organic chemist who developed it, and so will be written with authoritative, first-hand knowledge. This title is the first book to summarize new available methodologies for preparing ß-amino acids in optically pure form, a recent development in this field. The title also provides methods for synthesizing optically pure precursors to pharmacologically active substances, including ß-lacatams.
Author : Caroline Evans
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (824 download)
Download or read book A Novel Methodology for the Asymmetric Synthesis of Beta-lactams and Beta-amino Acids written by Caroline Evans and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The first example of an intramolecular ester enolate-imine cyclisation reaction for the asymmetric synthesis of polycyclic ~-Iactams and cyclic ~-amino acid derivatives has been developed. In Chapter 1, the synthesis of monocyclic ~-Iactams using intermolecular ester enolate- imine cyclisation reactions is reviewed. The use of chiral auxiliaries contained within the ester or imino functionality to control the diastereoselectivity of the reaction is discussed, as well as enantioselective approaches. The utilization of this methodology for the synthesis of natural products such as Taxol is described, as well as the use of polymer support protocols to improve the efficiency of this reaction. In Chapter 2, the synthesis of an appropriate cyclisation substrate containing an ester and imino functionality with a chiral auxiliary fragment is reported. Appropriate conditions were established that enabled an intramolecular enolate-imine cyclisation reaction to be used for the synthesis of the tricyclic ~-Iactam benzocispentacin in good yield and excellent de. The formation of ~-amino ester side products was investigated and an explanation for the production of ~-Iactams as major products over their corresponding ~-amino esters is proposed. This protocol was then applied to the asymmetric synthesis of six benzocispentacin derivatives all with good yields and excellent de, with the configuration of one of these derivatives being confirmed by X-ray crystallography. A deprotection methodology was then established to afford their corresponding tricyclic NH-~-Iactams and cis and trans bicyclic ~-amino esters. In Chapter 3, the newly devised methodology was also applied to acyclic substrates for the synthesis of the antifungal cispentacin. The ability to access both cis- and transpentacin in both high yields and excellent de as monomers for foldamer synthesis is reported.
![Download Enantioselective Synthesis of [Beta]-Amino Alcohols and [Beta]-Amino Acids PDF Online Free](https://books.google.com/books/content/images/frontcover/3NNANAAACAAJ?fife=w200-h370)
Author : Andrew Craig Donohue
Publisher :
ISBN 13 :
Total Pages : 368 pages
Book Rating : 4.:/5 (225 download)
Download or read book Enantioselective Synthesis of [Beta]-Amino Alcohols and [Beta]-Amino Acids written by Andrew Craig Donohue and published by . This book was released on 1997 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt:
![Download The Effects of Solvent on Enantioselective Synthesis of [beta]-amino Acids PDF Online Free](https://books.google.com/books/content/images/frontcover/yEiPHAAACAAJ?fife=w200-h370)
Author : Elizabeth A. Cormier
Publisher :
ISBN 13 :
Total Pages : 174 pages
Book Rating : 4.:/5 (564 download)
Download or read book The Effects of Solvent on Enantioselective Synthesis of [beta]-amino Acids written by Elizabeth A. Cormier and published by . This book was released on 2004 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt:
![Download Novel Methodologies for Enantioselective Synthesis of [beta]-amino Acid Derivatives PDF Online Free](https://books.google.com/books/content/images/frontcover/dN9qNwAACAAJ?fife=w200-h370)
Author : Mei Liu
Publisher :
ISBN 13 :
Total Pages : 696 pages
Book Rating : 4.:/5 (546 download)
Download or read book Novel Methodologies for Enantioselective Synthesis of [beta]-amino Acid Derivatives written by Mei Liu and published by . This book was released on 2002 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Ari M. P. Koskinen
Publisher :
ISBN 13 :
Total Pages : 234 pages
Book Rating : 4.:/5 (755 download)
Download or read book Asymmetric Synthesis of Natural Products written by Ari M. P. Koskinen and published by . This book was released on 1995 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Osamu Ichihara
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (62 download)
Download or read book Asymmetric Synthesis of Beta-amino Acids written by Osamu Ichihara and published by . This book was released on 1995 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
![Download Synthesis of Optically Active [alpha]-amino Acids PDF Online Free](https://books.google.com/books/content/images/frontcover/HLP2RAAACAAJ?fife=w200-h370)
Author : Robert Michael Williams
Publisher : Pergamon
ISBN 13 : 9780080359397
Total Pages : 410 pages
Book Rating : 4.3/5 (593 download)
Download or read book Synthesis of Optically Active [alpha]-amino Acids written by Robert Michael Williams and published by Pergamon. This book was released on 1989 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to review and critically evaluate the best new methods to synthesize alpha-amino acids in optically active form. There is so much new literature on amino acid synthesis that the experimentalist will undoubtedly have difficulty in selecting the most appropriate methodology for constructing the amino acid of immediate interest. This book is a guide for steering the scientist through the maze of existing reports on the subject and contains the most up-to-date critical reviews of methods of asymmetric synthesis of amino acids. In areas that are relatively new conceptually and less studied experimentally, an effort has been made to review the most salient works with an eye towards future development. Over 330 schemes and figures are presented with references for rapid visual retrieval of information. The book will be of great value to academic and industrial organic research chemists, especially those concerned with medicinal and agricultural chemistry, as well as to graduate and post graduate students, biochemists and biologists.
Download or read book Rare Americana a Very Unusual Collection of Books & Pamphlets Relating to the American Revolution, French and Indian War... Vente À New York, Le 8 Juillet 1919 Heartman's written by and published by . This book was released on 1919 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kent Sinching Chu
Publisher :
ISBN 13 :
Total Pages : 352 pages
Book Rating : 4.:/5 (47 download)
Download or read book Asymmetric Synthesis of Beta-aryl-beta-amino Acids and Completion of Total Synthesis of (+)-jasplakinolide written by Kent Sinching Chu and published by . This book was released on 1991 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Vivek Kothari
Publisher : Daya Books
ISBN 13 : 9788176221726
Total Pages : 284 pages
Book Rating : 4.2/5 (217 download)
Download or read book Biocatalytic Preparation of Amino Acids written by Vivek Kothari and published by Daya Books. This book was released on 2007 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amino Acids Are The Molecular Units That Make Up Proteins. All Proteins Are Various Compositions Of Twenty Specific Naturally Occurring Amino Acids. Amino Acids Are Found In All Foods Except Oil. There Are About Eighty Amino Acids Found In Nature, But Only Twenty To Twenty-Nine Are Required For Human Growth. Amino Acids Play A Pivotal Role In Living Systems, And Therefore Synthetic Amino Acids Have Been Of Significant Interest To Researchers Working Towards The Understanding And Modification Of Physiological Processes. Currently, The Amino Acids Used In Amino Acid Products Are Mainly Manufactured By Biocatalytic Methods. The Book Presents Detailed Discussion Of The Preparation Of Amino Acids By Biocatalysis. It Provides Examples Of Recently Developed Biocatalytic Methods For The Production Of Amino Acids And Its Derivatives. It Offers Upper Level Students And Professionals An Essential Resource For Pharmaceutical Development, Medicinal Chemistry And Biochemistry. Contents Chapter 1: Basics Of Biocatalysis; Chapter 2: Production Of Amino Acids; Chapter 3: Asymmetric Synthesis Of Amino Acids; Chapter 4: Amino Acids And Derivatives; Chapter 5: Strategies For Efficient Biocatalysis; Chapter 6: Synthesis Of Cage Amino Acids; Chapter 7: Types Of B-Amino Acids; Chapter 8: Extremophiles And Extremozymes; Chapter 9: Immobilised Enzymes; Chapter 10: Enzymatic Peptide Synthesis; Chapter 11: Synthesis Of Enantiomerically Pure (S)-Amino Acids And (R)-Amines; Chapter 12: Cloning And Sequence Analysis; Chapter 13: Bioseparation And Biocatalytic Applications.
Author : Naresh Theddu
Publisher :
ISBN 13 :
Total Pages : 238 pages
Book Rating : 4.:/5 (128 download)
Download or read book APPLICATIONS OF ENANTIOPURE SULFINIMINE DERIVED CHIRAL AMINE BUILDING BLOCKS FOR THE ASYMMETRIC SYNTHESIS OF TROPANE ALKALOIDS AND CYCLIC CIS BETA-AMINO ACID DERIVATIVES written by Naresh Theddu and published by . This book was released on 2011 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chiral amines are ubiquitous in natural products and are found in many drugs and drug candidates. Enantiopure sulfinimines [RS(O)N=CHR1] are useful chiral building blocks for the stereoselective synthesis of amines and amine derivatives. The aim of this thesis research is to develop new methods to access chiral amine building blocks for applications in the synthesis of nitrogen-heterocycles including ring-substituted tropinones, tropanes, cyclic cis-beta-amino acid derivatives, and amino-cyclopentitols.
Author : Andrew Sutherland
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (62 download)
Download or read book The Enantioselective Synthesis of Amino Acids for the Investigation of Protein Structure written by Andrew Sutherland and published by . This book was released on 1997 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
