Emerging Roles of Circular RNAs in the Tumor: Functions and Potential Applications

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Publisher : Frontiers Media SA
ISBN 13 : 2889745554
Total Pages : 315 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Emerging Roles of Circular RNAs in the Tumor: Functions and Potential Applications by : Mingli Liu

Download or read book Emerging Roles of Circular RNAs in the Tumor: Functions and Potential Applications written by Mingli Liu and published by Frontiers Media SA. This book was released on 2022-03-02 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt:

RNA-protein Interactions

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Publisher : Oxford University Press, USA
ISBN 13 :
Total Pages : 302 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis RNA-protein Interactions by : Kiyoshi Nagai

Download or read book RNA-protein Interactions written by Kiyoshi Nagai and published by Oxford University Press, USA. This book was released on 1994 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of RNA-protein interactions is crucial to understanding the mechanisms and control of gene expression and protein synthesis. The realization that RNAs are often far more biologically active than was previously appreciated has stimulated a great deal of new research in this field. Uniquely, in this book, the world's leading researchers have collaborated to produce a comprehensive and current review of RNA-protein interactions for all scientists working in this area. Timely, comprehensive, and authoritative, this new Frontiers title will be invaluable for all researchers in molecular biology, biochemistry and structural biology.

Circular RNAs

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Publisher : Springer
ISBN 13 : 9789811346323
Total Pages : 0 pages
Book Rating : 4.3/5 (463 download)

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Book Synopsis Circular RNAs by : Junjie Xiao

Download or read book Circular RNAs written by Junjie Xiao and published by Springer. This book was released on 2018-12-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an essential overview of the rapidly advancing field of circular RNAs – newly discovered RNAs that are generated by back-splicing precursor mRNA and perform regulatory functions in many biological processes. Although many aspects of circular RNAs’ biology and mechanisms of gene regulation remain unclear, they have been found to be abundant, evolutionally conserved, and stable in cells; further, they have numerous potential functions. The book consists of eight parts:1) An overview of circular RNAs, 2) Bioinformatics for circular RNAs, 3) Biogenesis of circular RNAs, 4) Molecular mechanisms and gene regulation of circular RNAs, 5) Circular RNAs as potential disease biomarkers, 6) Circular RNAs and human diseases, 7) Circular RNAs in Plants and in Archaea, and 8) Future prospects. Given its focus, the book will be especially useful for researchers and students in the fields of biochemistry, molecular biology, cell biology, and medicine.

Cancer and Noncoding RNAs

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Publisher : Academic Press
ISBN 13 : 0128134372
Total Pages : 578 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Cancer and Noncoding RNAs by : Jayprokas Chakrabarti

Download or read book Cancer and Noncoding RNAs written by Jayprokas Chakrabarti and published by Academic Press. This book was released on 2017-10-13 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer and Noncoding RNAs offers an in-depth exploration of noncoding RNAs and their role in epigenetic regulation of complex human disease, most notably cancer. In addition to examining microRNAs, this volume provides a unique evaluation of more recently profiled noncoding RNAs now implicated in carcinogenesis, including lncRNAs, piRNAs, circRNAs, and tRNAs, identifying differences in function between these noncoding RNAs and how they interact with the rest of the epigenome. A broad range of chapters from experts in the field detail epigenetic regulation of various cancer types, along with recent next generation sequencing technologies, genome-wide association studies (GWAS) and bioinformatics approaches. This book will help researchers in genomic medicine and cancer biology better understand the role of noncoding RNAs in epigenetics, aiding in the development of useful biomarkers for diagnosis, prognosis and new RNA-based disease therapies. - Provides a comprehensive analysis of noncoding RNAs implicated in epigenetic regulation of gene expression and chromatin dynamics - Educates researchers and graduate students by highlighting, in addition to miRNAs, a range of noncoding RNAs newly associated with carcinogenesis - Applies current knowledge of noncoding RNAs and epigenomics towards developing cancer and RNA-based disease therapies - Features contributions by leading experts in the field

Gene Expression and Phenotypic Traits

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Publisher : BoD – Books on Demand
ISBN 13 : 183880031X
Total Pages : 212 pages
Book Rating : 4.8/5 (388 download)

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Book Synopsis Gene Expression and Phenotypic Traits by : Yuan-Chuan Chen

Download or read book Gene Expression and Phenotypic Traits written by Yuan-Chuan Chen and published by BoD – Books on Demand. This book was released on 2020-04-01 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gene expression is the most fundamental level at which genotype gives rise to phenotype, which is an obvious, observable, and measurable trait. Phenotype is dependent on genetic makeup of the organism and influenced by environmental conditions. This book explores the significance, mechanism, function, characteristic, determination, and application of gene expression and phenotypic traits.

RNA/DNA and Cancer

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Publisher : Springer
ISBN 13 : 3319222791
Total Pages : 807 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis RNA/DNA and Cancer by : Joseph G. Sinkovics

Download or read book RNA/DNA and Cancer written by Joseph G. Sinkovics and published by Springer. This book was released on 2016-04-01 with total page 807 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, the author Joseph G. Sinkovics liberally shares his views on the cancer cell which he has been observing in vivo and in vitro, over a life time. Readers will learn how, as an inherent faculty of the RNA/DNA complex, the primordial cell survival pathways are endogenously reactivated in an amplified or constitutive manner in the multicellular host, and are either masquerading as self-elements or as placentas, to which the multicellular host is evolutionarily trained to extend full support. The host obliges. The author explains that there is no such evidence that “malignantly transformed” human cells survive in nature. However, when cared for in the laboratory, these cells live and replicate as immortalized cultures. These cells retain their vitality upon storage in liquid nitrogen. One can only imagine an astrophysical environment in which such cells could survive; perhaps, first their seemingly humble exosomes would populate that environment. Immortal cell populations so created may survive as individuals, or may even re-organize themselves into multicellular colonies, as representatives of life for the duration of the Universe. This thought-provoking book is the work of a disciplined investigator and clinician with an impeccable reputation, and he enters a territory that very few if any before him have approached from the same angles. It will appeal to researchers with an interest in cell survival pathways and those researching cancer cells.

Breast Cancer Metastasis and Drug Resistance

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Publisher : Springer Nature
ISBN 13 : 3030203018
Total Pages : 427 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Breast Cancer Metastasis and Drug Resistance by : Aamir Ahmad

Download or read book Breast Cancer Metastasis and Drug Resistance written by Aamir Ahmad and published by Springer Nature. This book was released on 2019-08-27 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Resistance to therapies, both targeted and systemic, and metastases to distant organs are the underlying causes of breast cancer-associated mortality. The second edition of Breast Cancer Metastasis and Drug Resistance brings together some of the leading experts to comprehensively understand breast cancer: the factors that make it lethal, and current research and clinical progress. This volume covers the following core topics: basic understanding of breast cancer (statistics, epidemiology, racial disparity and heterogeneity), metastasis and drug resistance (bone metastasis, trastuzumab resistance, tamoxifen resistance and novel therapeutic targets, including non-coding RNAs, inflammatory cytokines, cancer stem cells, ubiquitin ligases, tumor microenvironment and signaling pathways such as TRAIL, JAK-STAT and mTOR) and recent developments in the field (epigenetic regulation, microRNAs-mediated regulation, novel therapies and the clinically relevant 3D models). Experts also discuss the advances in laboratory research along with their translational and clinical implications with an overarching goal to improve the diagnosis and prognosis, particularly that of breast cancer patients with advanced disease.

NanoBioMedicine

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Publisher : Springer Nature
ISBN 13 : 9813298987
Total Pages : 510 pages
Book Rating : 4.8/5 (132 download)

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Book Synopsis NanoBioMedicine by : Shailendra K. Saxena

Download or read book NanoBioMedicine written by Shailendra K. Saxena and published by Springer Nature. This book was released on 2020-02-03 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the recent trends in various Nanotechnology-based therapeutics and challenges associated with its development. Nanobiotechnology is an interdisciplinary research that has wide applications in the various fields of biomedical research. The book discusses the various facets of the application of Nanotechnology in drug delivery, clinical diagnostics, Nanomedicine and treatment of infectious and chronic diseases. The book also highlights the recent advancements on important devices and applications that are based on Nanotechnology in medicine and brief the regulatory and ethical issues related to nanomedical devices. It also reviews the toxicological profile of various nanomaterials and emphasizes the need for safe nanomaterials for clinical use. Finally, the book discusses the recent developments of potential commercial applications of Nanotechnology.

RNA Technologies and Their Applications

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Publisher : Springer Science & Business Media
ISBN 13 : 3642121683
Total Pages : 460 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis RNA Technologies and Their Applications by : Volker A. Erdmann

Download or read book RNA Technologies and Their Applications written by Volker A. Erdmann and published by Springer Science & Business Media. This book was released on 2010-09-02 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: RNA technologies are the driving forces of modern medicine and biotechnology. They combine the fields of biochemistry, chemistry, molecular biology, cell biology, physics, nanotechnology and bioinformatics. The combination of these topics is set to revolutionize the medicine of tomorrow. After more than 15 years of extensive research in the field of RNA technologies, the first therapeutics are ready to reach the first patients. Thus we are witnessing the birth of a very exciting time in the development of molecular medicine, which will be based on the methods of RNA technologies. This volume is the first of a series. It covers various aspects of RNA interference and microRNAs, although antisense RNA applications, hammerhead ribozyme structure and function as well as non-coding RNAs are also discussed. The authors are internationally highly respected experts in the field of RNA technologies.

Nanopharmaceuticals: Principles and Applications Vol. 3

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Publisher : Springer Nature
ISBN 13 : 3030471209
Total Pages : 340 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Nanopharmaceuticals: Principles and Applications Vol. 3 by : Vinod Kumar Yata

Download or read book Nanopharmaceuticals: Principles and Applications Vol. 3 written by Vinod Kumar Yata and published by Springer Nature. This book was released on 2020-08-19 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the third volume on this subject and focuses on the recent advances of nanopharmaceuticals in cancer, dental, dermal and drug delivery applications and presents their safety, toxicity and therapeutic efficacy. The book also includes the transport phenomenon of nanomaterials and important pathways for drug delivery applications. It goes on to explain the toxicity of nanoparticles to different physiological systems and methods used to assess this for different organ systems using examples of in vivo systems.

The Molecular Biology of Cancer

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Publisher : John Wiley & Sons
ISBN 13 : 1444309080
Total Pages : 544 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis The Molecular Biology of Cancer by : Stella Pelengaris

Download or read book The Molecular Biology of Cancer written by Stella Pelengaris and published by John Wiley & Sons. This book was released on 2009-03-12 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive text provides a detailed overview of the molecular mechanisms underpinning the development of cancer and its treatment. Written by an international panel of researchers, specialists and practitioners in the field, the text discusses all aspects of cancer biology from the causes, development and diagnosis through to the treatment of cancer. Written by an international panel of researchers, specialists and practitioners in the field Covers both traditional areas of study and areas of controversy and emerging importance, highlighting future directions for research Features up-to-date coverage of recent studies and discoveries, as well as a solid grounding in the key concepts in the field Each chapter includes key points, chapter summaries, text boxes, and topical references for added comprehension and review Supported by a dedicated website at www.blackwellpublishing.com/pelengaris An excellent text for upper-level courses in the biology of cancer, for medical students and qualified practitioners preparing for higher exams, and for researchers and teachers in the field

Oral Cancer Detection

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Publisher : Springer
ISBN 13 : 3319612557
Total Pages : 314 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Oral Cancer Detection by : Prashanth Panta

Download or read book Oral Cancer Detection written by Prashanth Panta and published by Springer. This book was released on 2019-01-04 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph equips clinicians with the knowledge required to detect oral cancer at the earliest possible stage while simultaneously inspiring researchers to work on novel methods of detection. All the methods employed in the oral cancer context are considered, from simple ones like oral screening to more complex emerging optical methods and biomarker identification strategies. Individual chapters focus on conventional oral screening and application of vital stains, optical methods like white light based fluorescence-reflectance imaging, narrow band imaging, direct-oral-microscopy, and more advanced methods like optical coherence tomography, an in-vivo optical biopsy technique, and photo-acoustic imaging that allows visualization of deeper tissue changes. Novel electrical methods like bio-impedance assessment, occult biophysical methods like crystallization test, and the most promising salivary biomarkers and point-of-care opportunities are covered. Helpful information is also provided on essential topics including, oral potentially malignant disorders, biological aspects and molecular mechanisms underlying oral cancer progression, global epidemiology, concept of diagnostic delays, traditional imaging, and classic histopathology and microscopic features. The newer techniques are currently of active research interest, and can soon become powerful chair-side tools with potential to reduce diagnostic delays and improve survival.

Drug Resistance in the Treatment of Cancer

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Publisher : Cambridge University Press
ISBN 13 : 9780521473217
Total Pages : 344 pages
Book Rating : 4.4/5 (732 download)

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Book Synopsis Drug Resistance in the Treatment of Cancer by : Herbert M. Pinedo

Download or read book Drug Resistance in the Treatment of Cancer written by Herbert M. Pinedo and published by Cambridge University Press. This book was released on 1998-03-26 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: International authorities review the mechanisms and clinical implications of drug resistance in cancer.

Archaeal Ribosomes: Biogenesis, Structure and Function

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Publisher : Frontiers Media SA
ISBN 13 : 2889741419
Total Pages : 164 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Archaeal Ribosomes: Biogenesis, Structure and Function by : Paola Londei

Download or read book Archaeal Ribosomes: Biogenesis, Structure and Function written by Paola Londei and published by Frontiers Media SA. This book was released on 2022-01-24 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt:

MiRNomics

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Publisher :
ISBN 13 : 9781627037488
Total Pages : 333 pages
Book Rating : 4.0/5 (374 download)

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Book Synopsis MiRNomics by : Malik Yousef

Download or read book MiRNomics written by Malik Yousef and published by . This book was released on 2014 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: In miRNomics: MicroRNA Biology and Computational Analysis, expert researchers in the field present an overview of the current state of the art and aim to put the respective areas of research into a larger perspective. These include methods and techniques ranging from miRNA biogenesis, their biological function, computational analyses to their medical implications and applications. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, miRNomics: MicroRNA Biology and Computational Analysis seeks to aid scientists in the further study into miRNA research and statistics.

Circular RNAs

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Publisher : Humana Press
ISBN 13 : 9781493975617
Total Pages : 220 pages
Book Rating : 4.9/5 (756 download)

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Book Synopsis Circular RNAs by : Christoph Dieterich

Download or read book Circular RNAs written by Christoph Dieterich and published by Humana Press. This book was released on 2018-01-10 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides established approaches for identifying, characterizing, and manipulating circRNAs in vitro, in vivo, and in silico. Chapters highlight the breakthroughs and the challenges in this new field of research. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Circular RNAs: Methods and Protocols aims to useful and informative for further study into this vital field.

Emerging Molecular Mechanisms of Cell Cycle Regulation in Cancer: Functions and Potential Applications

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Publisher : Frontiers Media SA
ISBN 13 : 2889717690
Total Pages : 291 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Emerging Molecular Mechanisms of Cell Cycle Regulation in Cancer: Functions and Potential Applications by : Yueming Sun

Download or read book Emerging Molecular Mechanisms of Cell Cycle Regulation in Cancer: Functions and Potential Applications written by Yueming Sun and published by Frontiers Media SA. This book was released on 2022-03-07 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: