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Elucidating The Energetics Of Bacterial Signal Transduction
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Book Synopsis Molecular Mechanisms of Bacterial Virulence by : C.I. Kado
Download or read book Molecular Mechanisms of Bacterial Virulence written by C.I. Kado and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 676 pages. Available in PDF, EPUB and Kindle. Book excerpt: The growing body of information on bacteria pathogenic for humans, mammals and plants generated within the past ten years has shown the interesting conservation of newly identified genes that playa direct role in the pathogenic mechanism. In addition to these genes, there are also genes that confer host specificities and other traits important in pathogenesis on these pathogens. In this volume, we have organized the subject areas to best fit the concept on the way bacterial pathogens recognize, interact and invade the host, on the regulation of genes involved in virulence, on the genes involved in the elaboration of toxins and other pathogenic components such as iron sequestering proteins, and on the mechanisms of circumventing the host defense systems. These areas are divided into Sections. Section I covers the first step when the pathogen seeks its host, and Sections II through VI cover subsequent steps leading to pathogenesis while avoiding host defenses. We conclude this work with a chapter summarizing information on examples of virulence mechanisms that are highly conserved.
Book Synopsis Bacterial Energetics by : Terry Krulwich
Download or read book Bacterial Energetics written by Terry Krulwich and published by Elsevier. This book was released on 2012-12-02 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacterial Energetics deals with bacterial energetics and the molecular basis of how ions move between and within energy-transducing molecules. Topics covered range from respiration-driven proton pumps and primary sodium pumps to light-driven primary ionic pumps, bacterial transport ATPases, and bacterial photosynthesis. Sodium-coupled cotransport and ion-exchange systems in prokaryotes are also considered. This volume is comprised of 17 chapters and begins with an analysis of the pumps and processes that establish electrochemical ion gradients across bacterial membranes, followed by a discussion on the major types of bioenergetic work that utilize these gradients. The energetics of periplasmic transport systems, chemolithotrophs, methanogens, and protein insertion and translocation into or across membranes are also examined, along with bioenergetics in extreme environments such as high-pressure and high-temperature environments; energetic problems of bacterial fermentations; energetics of bacterial motility; and energetics of the bacterial phosphotransferase system in sugar transport and the regulation of carbon metabolism. This book should be of interest to molecular biologists and biochemists.
Book Synopsis Prokaryotic Metabolism and Physiology by : Byung Hong Kim
Download or read book Prokaryotic Metabolism and Physiology written by Byung Hong Kim and published by Cambridge University Press. This book was released on 2019-05-16 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensive and up-to-date review of key metabolic processes in bacteria and archaea and how metabolism is regulated under various conditions.
Download or read book Microbial Mats written by Yehuda Cohen and published by Wiley-Blackwell. This book was released on 1989 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprises the scientific presentation at Bat-Sheva de Rothschild seminar held at the H. Steinitz Marine Biology Lab in Eilat, Israel, Sept. 1987. Topics covered include: environments of depositions; structure and function of benthic microbial communities; regulation of adhesion and hydrophobicity of cell surfaces in the formation of microbial mats; physiology of major mat-building microorganisms. Forty contributions. Nicely produced on coated stock. Annotation copyrighted by Book News, Inc., Portland, OR
Book Synopsis Autotrophic Bacteria by : Hans Günter Schlegel
Download or read book Autotrophic Bacteria written by Hans Günter Schlegel and published by . This book was released on 1989 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Protein Sequencing and Identification Using Tandem Mass Spectrometry by : Michael Kinter
Download or read book Protein Sequencing and Identification Using Tandem Mass Spectrometry written by Michael Kinter and published by John Wiley & Sons. This book was released on 2005-04-12 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: How to design, execute, and interpret experiments for protein sequencing using mass spectrometry The rapid expansion of searchable protein and DNA databases in recent years has triggered an explosive growth in the application of mass spectrometry to protein sequencing. This timely and authoritative book provides professionals and scientists in biotechnology research with complete coverage of procedures for analyzing protein sequences by mass spectrometry, including step-by-step guidelines for sample preparation, analysis, and data interpretation. Michael Kinter and Nicholas Sherman present their own high-quality, laboratory-tested protocols for the analysis of a wide variety of samples, demonstrating how to carry out specific experiments and obtain fast, reliable results with a 99% success rate. Readers will get sufficient experimental detail to apply in their own laboratories, learn about the proper selection and operation of instruments, and gain essential insight into the fundamental principles of mass spectrometry and protein sequencing. Coverage includes: * Peptide fragmentation and interpretation of product ion spectra * Basic polyacrylamide gel electrophoresis * Preparation of protein digests for sequencing experiments * Mass spectrometric analysis using capillary liquid chromatography * Techniques for protein identification by database searches * Characterization of modified peptides using tandem mass spectrometry And much more
Book Synopsis The Bacteria: Bacterial energetics by : Irwin Clyde Gunsalus
Download or read book The Bacteria: Bacterial energetics written by Irwin Clyde Gunsalus and published by . This book was released on 1960 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Histidine Kinases in Signal Transduction by : Masayori Inouye
Download or read book Histidine Kinases in Signal Transduction written by Masayori Inouye and published by Elsevier. This book was released on 2002-11-13 with total page 539 pages. Available in PDF, EPUB and Kindle. Book excerpt: Living cells are constantly sensing environmental changes, and their abilities to sense these changes and adapt to them are essential for their survival. In bacteria, histidine kinases are the major sensors for these environmental stresses, enabling cells to adapt to new growth conditions. Written by leading experts in the field, this book provides an up-to-date and comprehensive review on the structure and function of histidine kinases. It also provides extensive information on the physiological roles of histidine kinases in bacteria and eukaryotes. An an essential reference for cell biologists, microbiologists, molecular biologists, and biochemists interested in signal transduction. Experimental biologists and pharmacologists studying signal transduction systems in living organisms will also find it a valuable research tool. - The first comprehensive book on the roles of histidine kinases in cells - 23 in-depth chapters written by leading experts in the field - Describes the most recent advances in the field of signal transduction
Book Synopsis The Science and Applications of Synthetic and Systems Biology by : Institute of Medicine
Download or read book The Science and Applications of Synthetic and Systems Biology written by Institute of Medicine and published by National Academies Press. This book was released on 2011-12-30 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.
Book Synopsis Antimicrobial Resistance and Implications for the 21st Century by : I.W. Fong
Download or read book Antimicrobial Resistance and Implications for the 21st Century written by I.W. Fong and published by Springer Science & Business Media. This book was released on 2007-11-15 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive, up-to-date volume defines the issues and offers potential solutions to the challenges of antimicrobial resistance. The chapter authors are leading international experts on antimicrobial resistance among a variety of bacteria, viruses including HIV and herpes, parasites and fungi. The chapters explore the molecular mechanisms of drug resistance, the immunology and epidemiology of resistance strains, clinical implications and implications on research and lack thereof, and prevention and future directions.
Download or read book Lasso Peptides written by Yanyan Li and published by Springer. This book was released on 2014-10-21 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lasso peptides form a growing family of fascinating ribosomally-synthesized and post-translationally modified peptides produced by bacteria. They contain 15 to 24 residues and share a unique interlocked topology that involves an N-terminal 7 to 9-residue macrolactam ring where the C-terminal tail is threaded and irreversibly trapped. The ring results from the condensation of the N-terminal amino group with a side-chain carboxylate of a glutamate at position 8 or 9, or an aspartate at position 7, 8 or 9. The trapping of the tail involves bulky amino acids located in the tail below and above the ring and/or disulfide bridges connecting the ring and the tail. Lasso peptides are subdivided into three subtypes depending on the absence (class II) or presence of one (class III) or two (class I) disulfide bridges. The lasso topology results in highly compact structures that give to lasso peptides an extraordinary stability towards both protease degradation and denaturing conditions. Lasso peptides are generally receptor antagonists, enzyme inhibitors and/or antibacterial or antiviral (anti-HIV) agents. The lasso scaffold and the associated biological activities shown by lasso peptides on different key targets make them promising molecules with high therapeutic potential. Their application in drug design has been exemplified by the development of an integrin antagonist based on a lasso peptide scaffold. The biosynthesis machinery of lasso peptides is therefore of high biotechnological interest, especially since such highly compact and stable structures have to date revealed inaccessible by peptide synthesis. Lasso peptides are produced from a linear precursor LasA, which undergoes a maturation process involving several steps, in particular cleavage of the leader peptide and cyclization. The post-translational modifications are ensured by a dedicated enzymatic machinery, which is composed of an ATP-dependent cysteine protease (LasB) and a lactam synthetase (LasC) that form an enzymatic complex called lasso synthetase. Microcin J25, produced by Escherichia coli AY25, is the archetype of lasso peptides and the most extensively studied. To date only around forty lasso peptides have been isolated, but genome mining approaches have revealed that they are widely distributed among Proteobacteria and Actinobacteria, particularly in Streptomyces, making available a rich resource of novel lasso peptides and enzyme machineries towards lasso topologies.
Book Synopsis Microbial Evolution and Co-Adaptation by : Institute of Medicine
Download or read book Microbial Evolution and Co-Adaptation written by Institute of Medicine and published by National Academies Press. This book was released on 2009-05-10 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Joshua Lederberg - scientist, Nobel laureate, visionary thinker, and friend of the Forum on Microbial Threats - died on February 2, 2008. It was in his honor that the Institute of Medicine's Forum on Microbial Threats convened a public workshop on May 20-21, 2008, to examine Dr. Lederberg's scientific and policy contributions to the marketplace of ideas in the life sciences, medicine, and public policy. The resulting workshop summary, Microbial Evolution and Co-Adaptation, demonstrates the extent to which conceptual and technological developments have, within a few short years, advanced our collective understanding of the microbiome, microbial genetics, microbial communities, and microbe-host-environment interactions.
Book Synopsis Signal Transduction by : Bastien D. Gomperts
Download or read book Signal Transduction written by Bastien D. Gomperts and published by Gulf Professional Publishing. This book was released on 2003-10-15 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Signal Transduction is a text reference on cellular signalling processes. Starting with the basics, it explains how cells respond to external cues (hormones, cytokines, neurotransmitters, adhesion molecules, extracellular matrix etc), and shows how these inputs are integrated and co-ordinated. The first half of the book provides the conceptual framework, explaining the formation and action of second messengers, particularly cyclic nucleotides and calcium, and the mediation of signal pathways by GTP-binding proteins. The remaining chapters deal with the formation of complex signalling cascades employed by cytokines and adhesion molecules, starting at the membrane and ending in the nucleus, there to regulate gene transcription. In this context, growth is an important potential outcome and this has relevance to the cellular transformations that underlie cancer. The book ends with a description at the molecular level of how signalling proteins interact with their environment and with each other through their structural domains. Each main topic is introduced with a historical essay, detailing the sources, key observations and experiments that set the scene for recent and current work.
Book Synopsis Bacterial Energetics by : Irwin Clyde Gunsalus
Download or read book Bacterial Energetics written by Irwin Clyde Gunsalus and published by . This book was released on 1990 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis A Textbook of Molecular Biotechnology by : Ashok K. Chauhan
Download or read book A Textbook of Molecular Biotechnology written by Ashok K. Chauhan and published by I. K. International Pvt Ltd. This book was released on 2009 with total page 1310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Textbook of Molecular Biotechnology covers an amazing range of topics from the basic structure of the cell and diversity of microorganisms to the latest techniques in the field of biotechnology. Various topics have been included for the benefit of graduate and postgraduate students. In addition, the book will be of immense help for the researchers and can be used as a laboratory manual for various biotechnological techniques. A number of reputed subject experts, scientists, academicians, and researchers have contributed their chapters to this volume. This book describes the role of basic biotechnological tools in various spheres of human society, namely, agriculture, nutraceuticals, pharmaceuticals, nanobiotechnology, proteomics, metagenomics and Intellectual Property rights.
Book Synopsis Bacterial Physiology and Metabolism by : Byung Hong Kim
Download or read book Bacterial Physiology and Metabolism written by Byung Hong Kim and published by Cambridge University Press. This book was released on 2008-02-21 with total page 934 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent determination of genome sequences for a wide range of bacteria has made in-depth knowledge of prokaryotic metabolic function essential in order to give biochemical, physiological, and ecological meaning to the genomic information. Clearly describing the important metabolic processes that occur in prokaryotes under different conditions and in different environments, this advanced text provides an overview of the key cellular processes that determine bacterial roles in the environment, biotechnology, and human health. Prokaryotic structure is described as well as the means by which nutrients are transported into cells across membranes. Glucose metabolism through glycolysis and the TCA cycle are discussed, as well as other trophic variations found in prokaryotes, including the use of organic compounds, anaerobic fermentation, anaerobic respiratory processes, and photosynthesis. The regulation of metabolism through control of gene expression and control of the activity of enzymes is also covered, as well as survival mechanisms used under starvation conditions.
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
