Elastic Filaments Of The Cell

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Elastic Filaments of the Cell

Author : H.L. Granzier
Publisher : Springer Science & Business Media
ISBN 13 : 1461542677
Total Pages : 427 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Elastic Filaments of the Cell by : H.L. Granzier

Download or read book Elastic Filaments of the Cell written by H.L. Granzier and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Elastic filaments refer mainly to titin, the largest of all known proteins. Titin was discovered initially in muscle cells, where it interconnects the thick filament with the Z-line. Titin forms a molecular spring that is responsible for maintaining the structural integrity of contracting muscle, ensuring efficient muscle contraction. More recently, it has become clear that titin is not restricted to muscle cells alone. For example, titin is found in chromosomes of neurons and also in blood platelets. This topic is fast becoming a focal point for research in understanding viscoelastic properties at the molecular, cellular, and tissue levels. In titin may lie a generic basis for biological viscoelasticity. It has become clear that titin may hold the key to certain clinical anomalies. For example, it is clear that titin-based ventricular stiffness is modulated by calcium and that titin is responsible for the altered stiffness in cardiomyopathies. It is also clear from evidence from a group of Finnish families that titin mutations may underlie some muscular dystrophies and that with other mutations chromatids fail to separate during mitosis. Thus, it is clear that this protein will have important clinical implications stemming from its biomechanical role. One aspect of this field is the bringing together of bioengineers with clinical researchers and biologists. Genetic and biochemical aspects of titin-related proteins are being studied together with front-line engineering approaches designed to measure the mechanics of titin either in small aggregates or in single molecules.

Molecular Biology of The Cell

Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of The Cell by : Bruce Alberts

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cell Biology by the Numbers

Author : Ron Milo
Publisher : Garland Science
ISBN 13 : 1317230698
Total Pages : 400 pages
Book Rating : 4.3/5 (172 download)

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Book Synopsis Cell Biology by the Numbers by : Ron Milo

Download or read book Cell Biology by the Numbers written by Ron Milo and published by Garland Science. This book was released on 2015-12-07 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid

Fascia: The Tensional Network of the Human Body - E-Book

Author : Robert Schleip
Publisher : Elsevier Health Sciences
ISBN 13 : 0702052280
Total Pages : 566 pages
Book Rating : 4.7/5 (2 download)

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Book Synopsis Fascia: The Tensional Network of the Human Body - E-Book by : Robert Schleip

Download or read book Fascia: The Tensional Network of the Human Body - E-Book written by Robert Schleip and published by Elsevier Health Sciences. This book was released on 2013-02-26 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the product of an important collaboration between clinicians of the manual therapies and scientists in several disciplines that grew out of the three recent International Fascia Research Congresses (Boston, Amsterdam, and Vancouver). The book editors, Thomas Findley MD PhD, Robert Schleip PhD, Peter Huijing PhD and Leon Chaitow DO, were major organizers of these congresses and used their extensive experience to select chapters and contributors for this book. This volume therefore brings together contributors from diverse backgrounds who share the desire to bridge the gap between theory and practice in our current knowledge of the fascia and goes beyond the 2007, 2009 and 2012 congresses to define the state-of-the-art, from both the clinical and scientific perspective. Prepared by over 100 specialists and researchers from throughout the world, Fascia: The Tensional Network of the Human Body will be ideal for all professionals who have an interest in fascia and human movement - physiotherapists, osteopathic physicians, osteopaths, chiropractors, structural integration practitioners, manual therapists, massage therapists, acupuncturists, yoga or Pilates instructors, exercise scientists and personal trainers - as well as physicians involved with musculoskeletal medicine, pain management and rehabilitation, and basic scientists working in the field. Reflects the efforts of almost 100 scientists and clinicians from throughout the world Offers comprehensive coverage ranging from anatomy and physiology, clinical conditions and associated therapies, to recently developed research techniques Explores the role of fascia as a bodywide communication system Presents the latest information available on myofascial force transmission which helps establish a scientific basis for given clinical experiences Explores the importance of fascia as a sensory organ - for example, its important proprioceptive and nociceptive functions which have implications for the generation of low back pain Describes new imaging methods which confirm the connectivity of organs and tissues Designed to organize relevant information for professionals involved in the therapeutic manipulation of the body’s connective tissue matrix (fascia) as well as for scientists involved in basic science research Reflects the increasing need for information about the properties of fascia, particularly for osteopaths, massage therapists, physiotherapists and other complementary health care professionals Offers new insights on the fascial related foundations of Traditional Chinese Medicine Meridians and the fascial effects of acupuncture

Designing Foods

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309037980
Total Pages : 384 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Designing Foods by : National Research Council

Download or read book Designing Foods written by National Research Council and published by National Academies Press. This book was released on 1988-02-01 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: This lively book examines recent trends in animal product consumption and diet; reviews industry efforts, policies, and programs aimed at improving the nutritional attributes of animal products; and offers suggestions for further research. In addition, the volume reviews dietary and health recommendations from major health organizations and notes specific target levels for nutrients.

Anatomy & Physiology

Author : Lindsay Biga
Publisher :
ISBN 13 : 9781955101158
Total Pages : pages
Book Rating : 4.1/5 (11 download)

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Book Synopsis Anatomy & Physiology by : Lindsay Biga

Download or read book Anatomy & Physiology written by Lindsay Biga and published by . This book was released on 2019-09-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: A version of the OpenStax text

Size Limits of Very Small Microorganisms

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309172748
Total Pages : 171 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Size Limits of Very Small Microorganisms by : National Research Council

Download or read book Size Limits of Very Small Microorganisms written by National Research Council and published by National Academies Press. This book was released on 1999-09-13 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: How small can a free-living organism be? On the surface, this question is straightforward-in principle, the smallest cells can be identified and measured. But understanding what factors determine this lower limit, and addressing the host of other questions that follow on from this knowledge, require a fundamental understanding of the chemistry and ecology of cellular life. The recent report of evidence for life in a martian meteorite and the prospect of searching for biological signatures in intelligently chosen samples from Mars and elsewhere bring a new immediacy to such questions. How do we recognize the morphological or chemical remnants of life in rocks deposited 4 billion years ago on another planet? Are the empirical limits on cell size identified by observation on Earth applicable to life wherever it may occur, or is minimum size a function of the particular chemistry of an individual planetary surface? These questions formed the focus of a workshop on the size limits of very small organisms, organized by the Steering .Group for the Workshop on Size Limits of Very Small Microorganisms and held on October 22 and 23, 1998. Eighteen invited panelists, representing fields ranging from cell biology and molecular genetics to paleontology and mineralogy, joined with an almost equal number of other participants in a wide-ranging exploration of minimum cell size and the challenge of interpreting micro- and nano-scale features of sedimentary rocks found on Earth or elsewhere in the solar system. This document contains the proceedings of that workshop. It includes position papers presented by the individual panelists, arranged by panel, along with a summary, for each of the four sessions, of extensive roundtable discussions that involved the panelists as well as other workshop participants.

Wound Healing

Author : Vlad Alexandrescu
Publisher : BoD – Books on Demand
ISBN 13 : 9535126784
Total Pages : 546 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Wound Healing by : Vlad Alexandrescu

Download or read book Wound Healing written by Vlad Alexandrescu and published by BoD – Books on Demand. This book was released on 2016-10-12 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: Outstanding scientific advances over the last decades unceasingly reveal real complexity of wound-healing process, astonishing in its staged progression, as life is unfolding itself. This natural course of tissue repair seems to bear thousands of overlapping molecular and macroscopic processes that nowadays only start to unfold to our knowledge. The present volume collecting recent scientific references proposes to readers a two-folded audacious goal. First, an updated design of intimate cellular mechanisms is entailed in tissue regeneration that emanates from the first section of the book. Next, a multidisciplinary therapeutic perspective that focuses on macroscopic healing throughout the second part of this work adds clinically integrated observation. Practical diagnostic and treatment information is appended in each chapter that may equally help experienced clinicians or dedicated students and researchers in broadening essential breaking points of their work. It is the wish of all multidisciplinary experts who gather prominent author's panel of this volume to incorporate latest medical reports and compel limits of current understanding for better tissue regeneration, limb salvage, and improved quality of life of our patients.

Prokaryotic Cytoskeletons

Author : Jan Löwe
Publisher : Springer
ISBN 13 : 331953047X
Total Pages : 450 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Prokaryotic Cytoskeletons by : Jan Löwe

Download or read book Prokaryotic Cytoskeletons written by Jan Löwe and published by Springer. This book was released on 2017-05-11 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the structures and functions of active protein filaments, found in bacteria and archaea, and now known to perform crucial roles in cell division and intra-cellular motility, as well as being essential for controlling cell shape and growth. These roles are possible because the cytoskeletal and cytomotive filaments provide long range order from small subunits. Studies of these filaments are therefore of central importance to understanding prokaryotic cell biology. The wide variation in subunit and polymer structure and its relationship with the range of functions also provide important insights into cell evolution, including the emergence of eukaryotic cells. Individual chapters, written by leading researchers, review the great advances made in the past 20-25 years, and still ongoing, to discover the architectures, dynamics and roles of filaments found in relevant model organisms. Others describe one of the families of dynamic filaments found in many species. The most common types of filament are deeply related to eukaryotic cytoskeletal proteins, notably actin and tubulin that polymerise and depolymerise under the control of nucleotide hydrolysis. Related systems are found to perform a variety of roles, depending on the organisms. Surprisingly, prokaryotes all lack the molecular motors associated with eukaryotic F-actin and microtubules. Archaea, but not bacteria, also have active filaments related to the eukaryotic ESCRT system. Non-dynamic fibres, including intermediate filament-like structures, are known to occur in some bacteria.. Details of known filament structures are discussed and related to what has been established about their molecular mechanisms, including current controversies. The final chapter covers the use of some of these dynamic filaments in Systems Biology research. The level of information in all chapters is suitable both for active researchers and for advanced students in courses involving bacterial or archaeal physiology, molecular microbiology, structural cell biology, molecular motility or evolution. Chapter 3 of this book is open access under a CC BY 4.0 license.

The Extracellular Matrix: an Overview

Author : Robert Mecham
Publisher : Springer Science & Business Media
ISBN 13 : 3642165559
Total Pages : 429 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis The Extracellular Matrix: an Overview by : Robert Mecham

Download or read book The Extracellular Matrix: an Overview written by Robert Mecham and published by Springer Science & Business Media. This book was released on 2011-02-16 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the series “Biology of Extracellular Matrix” provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment. Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.

Actin-based Motility

Author : Marie-France Carlier
Publisher : Springer Science & Business Media
ISBN 13 : 904819301X
Total Pages : 434 pages
Book Rating : 4.0/5 (481 download)

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Book Synopsis Actin-based Motility by : Marie-France Carlier

Download or read book Actin-based Motility written by Marie-France Carlier and published by Springer Science & Business Media. This book was released on 2010-09-23 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the discovery of actin by Straub in the 1950’s and the pioneering work of Oosawa on actin self-assembly in helical laments in the 1960’s, many books and conference proceedings have been published. As one of the most essential p- teins in life, essential for movement in organisms rangingfrom bacteria to higher eukaryotes, it is no surprise that actin has fascinated generations of scientists from many different elds. Actin can be considered as a “living treasure” of biology; the kinetics and thermodynamics of self-assembly, the dissipative nature of actin po- merization, the molecular interactions of monomeric and polymerized actin with regulators, the mechanical properties of actin gels, and more recently the force p- ducing motile and morphogenetic processes organized by the actin nanomachine in response to signaling, are all milestones in actin research. Discoveries that directly derive from and provide deeper insight into the fundamental properties of actin are constantly being made, making actin an ever appealing research molecule. At the same time, the explosion in new technologies and techniques in biological sciences has served to attract researchers from an expanding number of disciplines, to study actin. This book presents the latest developments of these new multiscale approaches of force and movement powered by self-assembly processes, with the hope to opening our perspectives on the many areas of actin-based motility research.

Mechanics of the Cell

Author : David H. Boal
Publisher : Cambridge University Press
ISBN 13 : 0521113768
Total Pages : 623 pages
Book Rating : 4.5/5 (211 download)

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Book Synopsis Mechanics of the Cell by : David H. Boal

Download or read book Mechanics of the Cell written by David H. Boal and published by Cambridge University Press. This book was released on 2012-01-19 with total page 623 pages. Available in PDF, EPUB and Kindle. Book excerpt: New edition exploring the mechanical features of biological cells for advanced undergraduate and graduate students in physics and biomedical engineering.

Fundamentals of Biomechanics

Author : Dawn L. Leger
Publisher : Springer Science & Business Media
ISBN 13 : 1475730675
Total Pages : 420 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Fundamentals of Biomechanics by : Dawn L. Leger

Download or read book Fundamentals of Biomechanics written by Dawn L. Leger and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensively revised from a successful first edition, this book features a wealth of clear illustrations, numerous worked examples, and many problem sets. It provides the quantitative perspective missing from more descriptive texts, without requiring an advanced background in mathematics, and as such will be welcomed for use in courses such as biomechanics and orthopedics, rehabilitation and industrial engineering, and occupational or sports medicine.

Nanoscale Photonic Imaging

Author : Tim Salditt
Publisher : Springer Nature
ISBN 13 : 3030344134
Total Pages : 634 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Nanoscale Photonic Imaging by : Tim Salditt

Download or read book Nanoscale Photonic Imaging written by Tim Salditt and published by Springer Nature. This book was released on 2020-06-09 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book, edited and authored by a team of world-leading researchers, provides a broad overview of advanced photonic methods for nanoscale visualization, as well as describing a range of fascinating in-depth studies. Introductory chapters cover the most relevant physics and basic methods that young researchers need to master in order to work effectively in the field of nanoscale photonic imaging, from physical first principles, to instrumentation, to mathematical foundations of imaging and data analysis. Subsequent chapters demonstrate how these cutting edge methods are applied to a variety of systems, including complex fluids and biomolecular systems, for visualizing their structure and dynamics, in space and on timescales extending over many orders of magnitude down to the femtosecond range. Progress in nanoscale photonic imaging in Göttingen has been the sum total of more than a decade of work by a wide range of scientists and mathematicians across disciplines, working together in a vibrant collaboration of a kind rarely matched. This volume presents the highlights of their research achievements and serves as a record of the unique and remarkable constellation of contributors, as well as looking ahead at the future prospects in this field. It will serve not only as a useful reference for experienced researchers but also as a valuable point of entry for newcomers.

Liquid Cell Electron Microscopy

Author : Frances M. Ross
Publisher : Cambridge University Press
ISBN 13 : 1107116570
Total Pages : 529 pages
Book Rating : 4.1/5 (71 download)

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Book Synopsis Liquid Cell Electron Microscopy by : Frances M. Ross

Download or read book Liquid Cell Electron Microscopy written by Frances M. Ross and published by Cambridge University Press. This book was released on 2017 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: 2.6.2 Electrodes for Electrochemistry

The Cytoskeleton

Author : James Spudich
Publisher :
ISBN 13 : 9780824331733
Total Pages : 0 pages
Book Rating : 4.3/5 (317 download)

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Book Synopsis The Cytoskeleton by : James Spudich

Download or read book The Cytoskeleton written by James Spudich and published by . This book was released on 1996 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Understanding Pulmonary Pathology

Author : Richard L. Kradin
Publisher : Academic Press
ISBN 13 : 0128014466
Total Pages : 358 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Understanding Pulmonary Pathology by : Richard L. Kradin

Download or read book Understanding Pulmonary Pathology written by Richard L. Kradin and published by Academic Press. This book was released on 2016-10-14 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding Pulmonary Pathology: Applying Pathological Findings in Therapeutic Decision Making provides a much needed reference tool for pathologists, practicing pulmonologists, and pulmonologist researchers. The unique approach to pulmonary pathology combines the multi-perspective views of the author who was trained formally as both a pulmonologist and as a pathologist. The book addresses what is often lost in translation when conveying the experience of pulmonary pathology in practicing pulmonary medicine. This important tool conveys detailed information concerning the anatomic basis of disease to those oriented towards thinking about diseases physiologically, providing the opportunity for optimal diagnosis, treatment of patients, and advancement of research. Bridges the knowledge gap between the pathologist, practicing pulmonologist, and pulmonologist researcher Contains a one-of-a-kind index that lists pathological terms and describes how they relate to disease diagnosis and impact pulmonary function Includes the current international guidelines with a critical analysis of how pathology is reflected within them Provides full-color, microscopic pictures on referenced topics