The Prevention and Treatment of Missing Data in Clinical Trials

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Author :
Publisher : National Academies Press
ISBN 13 : 030918651X
Total Pages : 163 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Prevention and Treatment of Missing Data in Clinical Trials by : National Research Council

Download or read book The Prevention and Treatment of Missing Data in Clinical Trials written by National Research Council and published by National Academies Press. This book was released on 2010-12-21 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: Randomized clinical trials are the primary tool for evaluating new medical interventions. Randomization provides for a fair comparison between treatment and control groups, balancing out, on average, distributions of known and unknown factors among the participants. Unfortunately, these studies often lack a substantial percentage of data. This missing data reduces the benefit provided by the randomization and introduces potential biases in the comparison of the treatment groups. Missing data can arise for a variety of reasons, including the inability or unwillingness of participants to meet appointments for evaluation. And in some studies, some or all of data collection ceases when participants discontinue study treatment. Existing guidelines for the design and conduct of clinical trials, and the analysis of the resulting data, provide only limited advice on how to handle missing data. Thus, approaches to the analysis of data with an appreciable amount of missing values tend to be ad hoc and variable. The Prevention and Treatment of Missing Data in Clinical Trials concludes that a more principled approach to design and analysis in the presence of missing data is both needed and possible. Such an approach needs to focus on two critical elements: (1) careful design and conduct to limit the amount and impact of missing data and (2) analysis that makes full use of information on all randomized participants and is based on careful attention to the assumptions about the nature of the missing data underlying estimates of treatment effects. In addition to the highest priority recommendations, the book offers more detailed recommendations on the conduct of clinical trials and techniques for analysis of trial data.

Collective Student Efficacy

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Author :
Publisher : Corwin Press
ISBN 13 : 1544383479
Total Pages : 185 pages
Book Rating : 4.5/5 (443 download)

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Book Synopsis Collective Student Efficacy by : John Hattie

Download or read book Collective Student Efficacy written by John Hattie and published by Corwin Press. This book was released on 2021-05-11 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: This innovative book details how knowledge, skills, and dispositions entangle to create collective and individual beliefs, and leads educators to mobilize collective efficacy in the classroom.

Efficacy of Drug Abuse Treatment Programs

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Publisher :
ISBN 13 :
Total Pages : 140 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis Efficacy of Drug Abuse Treatment Programs by : United States. Congress. House. Select Committee on Narcotics Abuse and Control

Download or read book Efficacy of Drug Abuse Treatment Programs written by United States. Congress. House. Select Committee on Narcotics Abuse and Control and published by . This book was released on 1989 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Self-efficacy

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Publisher :
ISBN 13 :
Total Pages : 604 pages
Book Rating : 4.:/5 (641 download)

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Book Synopsis Self-efficacy by : Albert Bandura

Download or read book Self-efficacy written by Albert Bandura and published by . This book was released on 1972 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Caffeine for the Sustainment of Mental Task Performance

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Author :
Publisher : National Academies Press
ISBN 13 : 0309082587
Total Pages : 172 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Caffeine for the Sustainment of Mental Task Performance by : Institute of Medicine

Download or read book Caffeine for the Sustainment of Mental Task Performance written by Institute of Medicine and published by National Academies Press. This book was released on 2002-01-07 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report from the Committee on Military Nutrition Research reviews the history of caffeine usage, the metabolism of caffeine, and its physiological effects. The effects of caffeine on physical performance, cognitive function and alertness, and alleviation of sleep deprivation impairments are discussed in light of recent scientific literature. The impact of caffeine consumption on various aspects of health, including cardiovascular disease, reproduction, bone mineral density, and fluid homeostasis are reviewed. The behavioral effects of caffeine are also discussed, including the effect of caffeine on reaction to stress, withdrawal effects, and detrimental effects of high intakes. The amounts of caffeine found to enhance vigilance and reaction time consistently are reviewed and recommendations are made with respect to amounts of caffeine appropriate for maintaining alertness of military personnel during field operations. Recommendations are also provided on the need for appropriate labeling of caffeine-containing supplements, and education of military personnel on the use of these supplements. A brief review of some alternatives to caffeine is also provided.

The Anthrax Vaccine

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Publisher : National Academies Press
ISBN 13 : 0309182743
Total Pages : 288 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Anthrax Vaccine by : Institute of Medicine

Download or read book The Anthrax Vaccine written by Institute of Medicine and published by National Academies Press. This book was released on 2002-04-18 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: The vaccine used to protect humans against the anthrax disease, called Anthrax Vaccine Adsorbed (AVA), was licensed in 1970. It was initially used to protect people who might be exposed to anthrax where they worked, such as veterinarians and textile plant workers who process animal hair. When the U. S. military began to administer the vaccine, then extended a plan for the mandatory vaccination of all U. S. service members, some raised concerns about the safety and efficacy of AVA and the manufacture of the vaccine. In response to these and other concerns, Congress directed the Department of Defense to support an independent examination of AVA. The Anthrax Vaccine: Is It Safe? Does It Work? reports the study's conclusion that the vaccine is acceptably safe and effective in protecting humans against anthrax. The book also includes a description of advances needed in main areas: improving the way the vaccine is now used, expanding surveillance efforts to detect side effects from its use, and developing a better vaccine.

Self-Efficacy in Changing Societies

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Publisher : Cambridge University Press
ISBN 13 : 9780521586962
Total Pages : 356 pages
Book Rating : 4.5/5 (869 download)

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Book Synopsis Self-Efficacy in Changing Societies by : Albert Bandura

Download or read book Self-Efficacy in Changing Societies written by Albert Bandura and published by Cambridge University Press. This book was released on 1997-05-13 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volume addresses important issues of human adaptation and change.

Efficacy of Stress Inoculation Training in improving the overall well-being of school students

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Publisher : Archers & Elevators Publishing House
ISBN 13 : 9388805100
Total Pages : pages
Book Rating : 4.3/5 (888 download)

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Book Synopsis Efficacy of Stress Inoculation Training in improving the overall well-being of school students by : Dr. Bani LekhaPhukan Dr. K. ArockiaMaraichelvi

Download or read book Efficacy of Stress Inoculation Training in improving the overall well-being of school students written by Dr. Bani LekhaPhukan Dr. K. ArockiaMaraichelvi and published by Archers & Elevators Publishing House. This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Gulf War Veterans

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Publisher : National Academies Press
ISBN 13 : 0309170494
Total Pages : 162 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Gulf War Veterans by : Institute of Medicine

Download or read book Gulf War Veterans written by Institute of Medicine and published by National Academies Press. This book was released on 2001-08-30 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ten years after the end of the Gulf War, questions continue to be raised about the health of U.S. service personnel who fought in that war. A primary concern is whether Gulf War veterans are receiving effective treatments for their health problems. Section 105 of the Veterans Program Enhancement Act of 1998 mandates that the Department of Veterans Affairs (VA) ask the Institute of Medicine (IOM) to convene a committee that would identify a method for assessing treatment effectiveness and describe already-validated treatments for Gulf War veterans' health problems, including the problem of medically unexplained symptoms. The specific charge to the committee is to (1) identify and describe approaches for assessing treatment effectiveness; (2) identify illnesses and conditions among veterans of the Gulf War, using data obtained from the VA and the Department of Defense (DoD) Gulf War Registries, as well as information in published articles; and (3) for these identified conditions and illnesses, identify validated models of treatment (to the extent that such treatments exist), or identify new approaches, theories, or research on the management of patients with these conditions if validated treatment models are not available.

Self-efficacy in Sport

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Author :
Publisher : Human Kinetics
ISBN 13 : 9780736059992
Total Pages : 424 pages
Book Rating : 4.0/5 (599 download)

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Book Synopsis Self-efficacy in Sport by : Deborah L. Feltz

Download or read book Self-efficacy in Sport written by Deborah L. Feltz and published by Human Kinetics. This book was released on 2008 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Self-belief, known as 'self-efficacy' by sports psychologists is widely believed to be an essential component of sporting success. This volume examines the nature of efficacy as it applies to sporting behaviour in coaches, athletes and teams.

Efficacy of Sound

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Publisher : University of Chicago Press
ISBN 13 : 0226828948
Total Pages : 255 pages
Book Rating : 4.2/5 (268 download)

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Book Synopsis Efficacy of Sound by : Ruthie Meadows

Download or read book Efficacy of Sound written by Ruthie Meadows and published by University of Chicago Press. This book was released on 2023-11-06 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book-length ethnographic study on music and Ifá divination in Cuba and Nigeria. Hailing from Cuba, Nigeria, and various sites across Latin America and the Caribbean, Ifá missionary-practitioners are transforming the landscape of Ifá divination and deity (òrìṣà/oricha) worship through transatlantic travel and reconnection. In Cuba, where Ifá and Santería emerged as an interrelated, Yorùbá-inspired ritual complex, worshippers are driven to “African traditionalism” by its promise of efficacy: they find Yorùbá approaches more powerful, potent, and efficacious. In the first book-length study on music and Ifá, Ruthie Meadows draws on extensive, multisited fieldwork in Cuba and Yorùbáland, Nigeria, to examine the controversial “Nigerian-style” ritual movement in Cuban Ifá divination. Meadows uses feminist and queer of color theory along with critical studies of Africanity to excavate the relation between utility and affect within translocal ritual music circulations. Meadows traces how translocal Ifá priestesses (ìyánífá), female batá drummers (bataleras), and priests (babaláwo) harness Yorùbá-centric approaches to ritual music and sound to heighten efficacy, achieve desired ritual outcomes, and reshape the conditions of their lives. Within a contentious religious landscape marked by the idiosyncrasies of revolutionary state policy, Nigerian-style Ifá-Òrìṣà is leveraged to transform femininity and masculinity, state religious policy, and transatlantic ritual authority on the island.

Self-Efficacy Beliefs of Adolescents

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Author :
Publisher : IAP
ISBN 13 : 1607527502
Total Pages : 379 pages
Book Rating : 4.6/5 (75 download)

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Book Synopsis Self-Efficacy Beliefs of Adolescents by : Tim Urdan

Download or read book Self-Efficacy Beliefs of Adolescents written by Tim Urdan and published by IAP. This book was released on 2006-02-01 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: The introduction of the psychological construct of self-efficacy is widely acknowledged as one of the most important developments in the history of psychology. Today, it is simply not possible to explain phenomena such as human motivation, learning, self-regulation, and accomplishment without discussing the role played by self-efficacy beliefs. In this, the fifth volume of our series on adolescence and education, we focus on the self-efficacy beliefs of adolescents. We are proud and fortunate to be able to bring together the most prominent voices in the study of self-efficacy, including that of the Father of Social Cognitive Theory and of self-efficacy, Professor Albert Bandura. It is our hope, and our expectation, that this volume will become required reading for all students and scholars in the areas of adolescence and of motivation and, of course, for all who play a pivotal role in the education and care of youth.

The Efficacy of Augmentative and Alternative Communication

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Author :
Publisher : BRILL
ISBN 13 : 0585492263
Total Pages : 651 pages
Book Rating : 4.5/5 (854 download)

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Book Synopsis The Efficacy of Augmentative and Alternative Communication by : Ralf W. Schlosser

Download or read book The Efficacy of Augmentative and Alternative Communication written by Ralf W. Schlosser and published by BRILL. This book was released on 2023-02-06 with total page 651 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides the essential tools for appraising evidence and outlining steps for planning and implementing better efficacy research. This book aims to help researchers and practitioners develop the necessary skills for moving the augmentative and alternative communication field toward evidence-based practice.

Beyond the HIPAA Privacy Rule

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Publisher : National Academies Press
ISBN 13 : 0309124999
Total Pages : 334 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Beyond the HIPAA Privacy Rule by : Institute of Medicine

Download or read book Beyond the HIPAA Privacy Rule written by Institute of Medicine and published by National Academies Press. This book was released on 2009-03-24 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the realm of health care, privacy protections are needed to preserve patients' dignity and prevent possible harms. Ten years ago, to address these concerns as well as set guidelines for ethical health research, Congress called for a set of federal standards now known as the HIPAA Privacy Rule. In its 2009 report, Beyond the HIPAA Privacy Rule: Enhancing Privacy, Improving Health Through Research, the Institute of Medicine's Committee on Health Research and the Privacy of Health Information concludes that the HIPAA Privacy Rule does not protect privacy as well as it should, and that it impedes important health research.

Safe and Effective Medicines for Children

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Publisher : National Academies Press
ISBN 13 : 0309225493
Total Pages : 432 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Safe and Effective Medicines for Children by : Institute of Medicine

Download or read book Safe and Effective Medicines for Children written by Institute of Medicine and published by National Academies Press. This book was released on 2012-10-13 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Best Pharmaceuticals for Children Act (BPCA) and the Pediatric Research Equity Act (PREA) were designed to encourage more pediatric studies of drugs used for children. The FDA asked the IOM to review aspects of pediatric studies and changes in product labeling that resulted from BPCA and PREA and their predecessor policies, as well as assess the incentives for pediatric studies of biologics and the extent to which biologics have been studied in children. The IOM committee concludes that these policies have helped provide clinicians who care for children with better information about the efficacy, safety, and appropriate prescribing of drugs. The IOM suggests that more can be done to increase knowledge about drugs used by children and thereby improve the clinical care, health, and well-being of the nation's children.

The Dark Lord

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Publisher : Tor Books
ISBN 13 : 0765390817
Total Pages : 975 pages
Book Rating : 4.7/5 (653 download)

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Book Synopsis The Dark Lord by : Thomas Harlan

Download or read book The Dark Lord written by Thomas Harlan and published by Tor Books. This book was released on 2016-01-12 with total page 975 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tom Harlan brings his Oath of Empire series to a shattering conclusion in The Dark Lord. In what would be the 7th Century AD in our history, the Roman Empire still stands, supported by the twin pillars of the Legions and Thaumaturges of Rome. The Emperor of the West, the Augustus Galen Atreus, came to the aid of the Emperor of the East, the Avtokrator Heraclius, in his war with the Sassanad Emperor of Persia. But despite early victories, that war has not gone well, and now Rome is hard-pressed. Constantinople has fallen before the dark sorceries of the Lord Dahak and his legions of the living and dead. Now the new Emperor of Persia marches on Egypt, and if he takes that ancient nation, Rome will be starved and defeated. But there is a faint glimmer of hope. The Emperor Galen's brother Maxian is a great sorcerer, perhaps the equal of Dahak, lord of the seven serpents. He is now firmly allied with his Imperial brother and Rome. And though they are caught tight in the Dark Lord's net of sorcery, Queen Zoe of Palmyra and Lord Mohammed have not relinquished their souls to evil. Powerful, complex, engrossing --Thomas Harlan's Oath of Empire series has taken fantasy readers by storm. The first three volumes, The Shadow of Ararat, The Gate of Fire, and The Storm of Heaven have been universally praised. At the Publisher's request, this title is being sold without Digital Rights Management Software (DRM) applied.

Observation and Experiment

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Publisher : Harvard University Press
ISBN 13 : 067497557X
Total Pages : 395 pages
Book Rating : 4.6/5 (749 download)

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Book Synopsis Observation and Experiment by : Paul Rosenbaum

Download or read book Observation and Experiment written by Paul Rosenbaum and published by Harvard University Press. This book was released on 2017-08-14 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: A daily glass of wine prolongs life—yet alcohol can cause life-threatening cancer. Some say raising the minimum wage will decrease inequality while others say it increases unemployment. Scientists once confidently claimed that hormone replacement therapy reduced the risk of heart disease but now they equally confidently claim it raises that risk. What should we make of this endless barrage of conflicting claims? Observation and Experiment is an introduction to causal inference by one of the field’s leading scholars. An award-winning professor at Wharton, Paul Rosenbaum explains key concepts and methods through lively examples that make abstract principles accessible. He draws his examples from clinical medicine, economics, public health, epidemiology, clinical psychology, and psychiatry to explain how randomized control trials are conceived and designed, how they differ from observational studies, and what techniques are available to mitigate their bias. “Carefully and precisely written...reflecting superb statistical understanding, all communicated with the skill of a master teacher.” —Stephen M. Stigler, author of The Seven Pillars of Statistical Wisdom “An excellent introduction...Well-written and thoughtful...from one of causal inference’s noted experts.” —Journal of the American Statistical Association “Rosenbaum is a gifted expositor...an outstanding introduction to the topic for anyone who is interested in understanding the basic ideas and approaches to causal inference.” —Psychometrika “A very valuable contribution...Highly recommended.” —International Statistical Review