Effects Of Renal Denervation Vs Sham In Resistant Hypertension After Medication Escalation

Download Effects Of Renal Denervation Vs Sham In Resistant Hypertension After Medication Escalation full books in PDF, epub, and Kindle. Read online Effects Of Renal Denervation Vs Sham In Resistant Hypertension After Medication Escalation ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Effects of Renal Denervation Vs Sham in Resistant Hypertension After Medication Escalation

Author : Michel Azizi
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (137 download)

DOWNLOAD NOW!

Book Synopsis Effects of Renal Denervation Vs Sham in Resistant Hypertension After Medication Escalation by : Michel Azizi

Download or read book Effects of Renal Denervation Vs Sham in Resistant Hypertension After Medication Escalation written by Michel Azizi and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: Importance Although early trials of endovascular renal denervation (RDN) for patients with resistant hypertension (RHTN) reported inconsistent results, ultrasound RDN (uRDN) was found to decrease blood pressure (BP) vs sham at 2 months in patients with RHTN taking stable background medications in the Study of the ReCor Medical Paradise System in Clinical Hypertension (RADIANCE-HTN TRIO) trial. Objectives To report the prespecified analysis of the persistence of the BP effects and safety of uRDN vs sham at 6 months in conjunction with escalating antihypertensive medications. Design, Setting, and Participants This randomized, sham-controlled, clinical trial with outcome assessors and patients blinded to treatment assignment, enrolled patients from March 11, 2016, to March 13, 2020. This was an international, multicenter study conducted in the US and Europe. Participants with daytime ambulatory BP of 135/85 mm Hg or higher after 4 weeks of single-pill triple-combination treatment (angiotensin-receptor blocker, calcium channel blocker, and thiazide diuretic) with estimated glomerular filtration rate (eGFR) of 40 mL/min/1.73 m2 or greater were randomly assigned to uRDN or sham with medications unchanged through 2 months. From 2 to 5 months, if monthly home BP was 135/85 mm Hg or higher, standardized stepped-care antihypertensive treatment starting with aldosterone antagonists was initiated under blinding to treatment assignment. Interventions uRDN vs sham procedure in conjunction with added medications to target BP control. Main Outcomes and Measures Six-month change in medications, change in daytime ambulatory systolic BP, change in home systolic BP adjusted for baseline BP and medications, and safety. Results A total of 65 of 69 participants in the uRDN group and 64 of 67 participants in the sham group (mean [SD] age, 52.4 [8.3] years; 104 male [80.6%]) with a mean (SD) eGFR of 81.5 (22.8) mL/min/1.73 m2 had 6-month daytime ambulatory BP measurements. Fewer medications were added in the uRDN group (mean [SD], 0.7 [1.0] medications) vs sham (mean [SD], 1.1 [1.1] medications; P = .045) and fewer patients in the uRDN group received aldosterone antagonists at 6 months (26 of 65 [40.0%] vs 39 of 64 [60.9%]; P = .02). Despite less intensive standardized stepped-care antihypertensive treatment, mean (SD) daytime ambulatory BP at 6 months was 138.3 (15.1) mm Hg with uRDN vs 139.0 (14.3) mm Hg with sham (additional decreases of −2.4 [16.6] vs −7.0 [16.7] mm Hg from month 2, respectively), whereas home SBP was lowered to a greater extent with uRDN by 4.3 mm Hg (95% CI, 0.5-8.1 mm Hg; P = .03) in a mixed model adjusting for baseline and number of medications. Adverse events were infrequent and similar between groups. Conclusions and Relevance In this study, in patients with RHTN initially randomly assigned to uRDN or a sham procedure and who had persistent elevation of BP at 2 months after the procedure, standardized stepped-care antihypertensive treatment escalation resulted in similar BP reduction in both groups at 6 months, with fewer additional medications required in the uRDN group. Trial Registration ClinicalTrials.gov Identifier: NCT02649426

Renal Denervation

Author : Richard R. Heuser
Publisher : Springer
ISBN 13 : 1447152239
Total Pages : 203 pages
Book Rating : 4.4/5 (471 download)

DOWNLOAD NOW!

Book Synopsis Renal Denervation by : Richard R. Heuser

Download or read book Renal Denervation written by Richard R. Heuser and published by Springer. This book was released on 2014-11-11 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hypertension remains the leading cause of cardiovascular morbidity and mortality in spite of current medical therapies. It has been estimated that 50% of Western civilization has hypertension and approximately 20% of patients have resistant hypertension. Renal denervation (RDN) is a minimally invasive, endovascular catheter based procedure using radiofrequency ablation aimed at treating resistant hypertension. Early studies show a high degree of effectiveness in renal denervation to treat hypertension. This book examines renal pathophysiology and the rationale for renal denervation, as well as possible long term benefits and risks of this new therapy. The myriad of devices involved in the evolution of this therapy are discussed and the book concludes with analyses of the cost effectiveness and future applications.

Renal denervation

Author : Flavio L. RIBICHINI
Publisher : Edizioni Minerva Medica SpA
ISBN 13 : 885532232X
Total Pages : 154 pages
Book Rating : 4.8/5 (553 download)

DOWNLOAD NOW!

Book Synopsis Renal denervation by : Flavio L. RIBICHINI

Download or read book Renal denervation written by Flavio L. RIBICHINI and published by Edizioni Minerva Medica SpA. This book was released on 2024-02-27 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Renal Denervation handbook is a practical “all you need to know” guide to treating patients with hypertension. Renal Denervation is a revolutionary, minimally invasive trans-catheter intervention that has emerged as a safe and effective therapeutic companion for the limited number of patients with resistant hypertension and the huge population of those who “resist” to take their prescribed medications. Written by the world’s most recognized experts in the field, the handbook provides a review of the scientific bases of the therapy, reveals practical instructions on how to select the right patients and perform the procedure, and analyzes clinical results in a direct, easy to understand style. This guide is the resource for all healthcare providers interested in the modern management of hypertension and successfully managing the number one risk factor for stroke, myocardial infarction, and heart failure worldwide.

Renal Denervation for Treatment-Resistant Hypertension

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (1 download)

DOWNLOAD NOW!

Book Synopsis Renal Denervation for Treatment-Resistant Hypertension by :

Download or read book Renal Denervation for Treatment-Resistant Hypertension written by and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Diabetes and Hypertension

Author : Samy I. McFarlane
Publisher : Springer Science & Business Media
ISBN 13 : 1603273573
Total Pages : 196 pages
Book Rating : 4.6/5 (32 download)

DOWNLOAD NOW!

Book Synopsis Diabetes and Hypertension by : Samy I. McFarlane

Download or read book Diabetes and Hypertension written by Samy I. McFarlane and published by Springer Science & Business Media. This book was released on 2012-10-19 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes and hypertension have evolved as two of the modern day epidemics affecting millions of people around the world. These two common co-morbidities lead to substantial increase in cardiovascular disease, the major cause of morbidity and mortality of adults around the world. In Diabetes and Hypertension: Evaluation and Management, a panel of renowned experts address a range of critical topics -- from basic concepts in evaluation and management of diabetes and hypertension, such as dietary interventions, to evaluation and management of secondary hypertension in clinical practice. Other chapters focus on high cardiovascular risk populations such as those with coronary heart disease, chronic kidney disease and minority patients. In addition, evolving concepts and new developments in the field are presented in other chapters, such as prevention of type 2 diabetes and the epidemic of sleep apnea and its implication for diabetes and hypertension evaluation and management. An important title covering two of the most troubling disorders of our time, Diabetes and Hypertension: Evaluation and Management will provide the busy practitioner with cutting edge knowledge in the field as well as practical information that can translate into better care provided to the high-risk population of diabetics and hypertensive patients.

Pain Management and the Opioid Epidemic

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309459575
Total Pages : 483 pages
Book Rating : 4.3/5 (94 download)

DOWNLOAD NOW!

Book Synopsis Pain Management and the Opioid Epidemic by : National Academies of Sciences, Engineering, and Medicine

Download or read book Pain Management and the Opioid Epidemic written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-09-28 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

Prevention and Treatment of Atherosclerosis

Author : Arnold von Eckardstein
Publisher : Springer Nature
ISBN 13 : 3030860760
Total Pages : 537 pages
Book Rating : 4.0/5 (38 download)

DOWNLOAD NOW!

Book Synopsis Prevention and Treatment of Atherosclerosis by : Arnold von Eckardstein

Download or read book Prevention and Treatment of Atherosclerosis written by Arnold von Eckardstein and published by Springer Nature. This book was released on 2022 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book is supported by the European Atherosclerosis Society Association (EAS). This follow-up edition of the well-received Handbook volume 'Atherosclerosis: Diet and Drugs' reflects the state-of-the-art and most recent developments in atherosclerosis research. Outstanding international experts give a comprehensive overview of the field covering topics, such as improving the treatment focusing on established targets, novel drug developments addressing pre-defined targets, hypothesis-based and hypothesis-free approaches to unravel novel targets.

Drug Adherence in Hypertension and Cardiovascular Protection

Author : Michel Burnier
Publisher : Springer
ISBN 13 : 3319765930
Total Pages : 305 pages
Book Rating : 4.3/5 (197 download)

DOWNLOAD NOW!

Book Synopsis Drug Adherence in Hypertension and Cardiovascular Protection by : Michel Burnier

Download or read book Drug Adherence in Hypertension and Cardiovascular Protection written by Michel Burnier and published by Springer. This book was released on 2018-06-27 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a critical and comprehensive review of the methodologies available for measuring drug adherence in clinical practice, including those relying on emerging technologies. The authors discuss the risk factors of non-adherence and shed light on how to identify patients at risk of poor adherence. Drug therapies in chronic diseases rely heavily on the patient's adherence, since drugs that are not taken are ineffective and leave the patient at high risk of developing clinical complications. Given the absence of new drugs for the treatment of hypertension, drug adherence is particularly important in these patients to improve blood pressure control. The book further investigates a new aspect, namely the importance of drug adherence in clinical trials and studies and draws attention to the limits of developing drugs without significant information on drug adherence. Several chapters are dedicated to the importance of adherence in specific forms of hypertension, such as resistant hypertension, dyslipidemia and hypertension associated with cardiovascular risk. As experts confronted with drug adherence in their daily practice, the authors analyse the real effectiveness of several interventions aimed at improving drug adherence and put particular emphasis on the importance of an interdisciplinary approach involving nurses and pharmacists. The volume also includes a careful analysis of the health and economic impact of poor adherence. The book is aimed at physicians, pharmacists, students and all health professionals dealing not only with hypertension or dyslipidemia, but also with chronic asymptomatic diseases such as diabetes, HIV or chronic respiratory diseases.

Essentials of Hypertension

Author : Flávio Danni Fuchs
Publisher : Springer
ISBN 13 : 3319632728
Total Pages : 161 pages
Book Rating : 4.3/5 (196 download)

DOWNLOAD NOW!

Book Synopsis Essentials of Hypertension by : Flávio Danni Fuchs

Download or read book Essentials of Hypertension written by Flávio Danni Fuchs and published by Springer. This book was released on 2017-11-20 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: The main purpose of this book is to select and present the most essential information about hypertension. It aims to select all the more relevant data to guide the attitudes to prevent, diagnose, and treat hypertension. Hypertension accounts for more than 50% of deaths from stroke and ischemic heart disease worldwide. New blood pressure (BP) diagnostic thresholds for hypertension were released, which were set at 130/80 mmHg. As a consequence, millions of individuals in the world will be diagnosed as hypertensive, recognizing that they are at greater risk of presenting a CV event. Prevention and control of high BP will become the main focus for reducing the burden of CV disease, requiring a changing of cultural beliefs in some way similar to what happened in the last century with smoking. Strategies for prevention of the rising of BP with age, and the BP reduction in individuals already with high levels, are more complex than those related to smoking control. These strategies involve solid evidence to be implemented in populations. The extensive scientific literature dealing with hypertension and BP regulation is among the top dedicated to a single disease. The chapters and contents follow the clinical reasoning pathways. The characterization of the risks of high blood pressure is presented in the first chapter, discussing the evidence that led to changes in diagnostic thresholds and to the recommendations for maintaining BP within these limits in populations. Reasons for BP rising with age will follow, identifying the causes that must be fought to preventing the incidence of hypertension. Diagnosis of hypertension deserves a special chapter. The final chapter presents the fundamentals to select drug and non-drug therapies indicated in the prevention and controlling of high blood pressure.

The Pain Management Handbook

Author : M. Eric Gershwin
Publisher : Springer Science & Business Media
ISBN 13 : 9780896034235
Total Pages : 400 pages
Book Rating : 4.0/5 (342 download)

DOWNLOAD NOW!

Book Synopsis The Pain Management Handbook by : M. Eric Gershwin

Download or read book The Pain Management Handbook written by M. Eric Gershwin and published by Springer Science & Business Media. This book was released on 1998-03-10 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Seasoned clinicians comprehensively, yet succinctly, summarize their years of experience in the diagnosis and treatment of acute and chronic pain across a wide variety of medical conditions. Drawing on their extensive personal knowledge of internal medicine, family practice, rheumatology, neurology, cardiology, as well as of urology, oncology, neurology, physical medicine, and gastroenterology, they provide all the practical information needed by busy practitioners to initiate appropriate diagnostic tests and therapy-without having to consult other references. Treatment is presented in practical terms, with specific but full information given on medications and dosages.

Handbook of ICU Therapy

Author : Ian McConachie
Publisher : Cambridge University Press
ISBN 13 : 0521678579
Total Pages : 453 pages
Book Rating : 4.5/5 (216 download)

DOWNLOAD NOW!

Book Synopsis Handbook of ICU Therapy by : Ian McConachie

Download or read book Handbook of ICU Therapy written by Ian McConachie and published by Cambridge University Press. This book was released on 2006-01-12 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of ICU Therapy provides rapid access to important information on the treatment of the critically ill patient. It comprises a series of 'cutting edge' reviews of the most advanced treatment concepts available in the modern ICU. Whilst assuming a basic knowledge of underlying conditions, it nonetheless outlines key physiological principles where necessary, and critically reviews current literature and best practice. The heart of the book is aimed at providing key practical information on treatment techniques to the busy clinician in an easily accessible style. In addition to conventional drug therapy, ventilator, fluid and physical therapies are also discussed in detail. All of the authors are directly involved in ICU research and practice and are familiar with all of the latest developments in this fast-moving field of medicine.

Academic Pain Medicine

Author : Yury Khelemsky
Publisher : Springer
ISBN 13 : 3030180050
Total Pages : 386 pages
Book Rating : 4.0/5 (31 download)

DOWNLOAD NOW!

Book Synopsis Academic Pain Medicine by : Yury Khelemsky

Download or read book Academic Pain Medicine written by Yury Khelemsky and published by Springer. This book was released on 2019-07-23 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive text is the definitive academic pain medicine resource for medical students, residents and fellows. Acting as both an introduction and continued reference for various levels of training, this guide provides practitioners with up-to-date academic standards. In order to comprehensively meet the need for such a contemporary text—treatment options, types of pain management, and variables affecting specific conditions are thoroughly examined across 48 chapters. Categories of pain conditions include orofacial, neuropathic, visceral, neck, acute, muscle and myofascial, chronic urogenital and pelvic, acute, and regional. Written by renowned experts in the field, each chapter is supplemented with high-quality color figures, tables and images that provide the reader with a fully immersive educational experience. Academic Pain Medicine: A Practical Guide to Rotations, Fellowship, and Beyond is an unprecedented contribution to the literature that addresses the wide-spread requisite for a practical guide to pain medicine within the academic environment.

Postural Tachycardia Syndrome

Author : Nicholas Gall
Publisher : Springer Nature
ISBN 13 : 3030541657
Total Pages : 316 pages
Book Rating : 4.0/5 (35 download)

DOWNLOAD NOW!

Book Synopsis Postural Tachycardia Syndrome by : Nicholas Gall

Download or read book Postural Tachycardia Syndrome written by Nicholas Gall and published by Springer Nature. This book was released on 2020-10-21 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the varying clinical manifestations of postural tachycardia syndrome (PoTS) and provides a robust yet practical set of clinical tools for those managing patients suffering with this syndrome. Guidance is provided by a range of disciplines relevant to PoTS including general and specialist assessments, associated conditions, diagnostic considerations, therapy and service models. Postural Tachycardia Syndrome: A Concise and Practical Guide to Management and Associated Conditions presents the scientific background and practical information for the busy medical professional, illustrating key features with care-based materials to help them manage this condition, which can be a challenge for patients and clinicians alike.

Home Blood Pressure Monitoring

Author : George S. Stergiou
Publisher : Springer Nature
ISBN 13 : 3030230651
Total Pages : 174 pages
Book Rating : 4.0/5 (32 download)

DOWNLOAD NOW!

Book Synopsis Home Blood Pressure Monitoring by : George S. Stergiou

Download or read book Home Blood Pressure Monitoring written by George S. Stergiou and published by Springer Nature. This book was released on 2019-10-31 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hypertension remains a leading cause of disability and death worldwide. Self-monitoring of blood pressure by patients at home is currently recommended as a valuable tool for the diagnosis and management of hypertension. Unfortunately, in clinical practice, home blood pressure monitoring is often inadequately implemented, mostly due to the use of inaccurate devices and inappropriate methodologies. Thus, the potential of the method to improve the management of hypertension and cardiovascular disease prevention has not yet been exhausted. This volume presents the available evidence on home blood pressure monitoring, discusses its strengths and limitations, and presents strategies for its optimal implementation in clinical practice. Written by distinguished international experts, it offers a complete source of information and guide for practitioners and researchers dealing with the management of hypertension.

Low Back Disorders

Author : Stuart McGill
Publisher : Human Kinetics
ISBN 13 : 9780736066921
Total Pages : 336 pages
Book Rating : 4.0/5 (669 download)

DOWNLOAD NOW!

Book Synopsis Low Back Disorders by : Stuart McGill

Download or read book Low Back Disorders written by Stuart McGill and published by Human Kinetics. This book was released on 2007 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition of 'Low Back Disorders' provides research information on low back problems and shows readers how to interpret the data for clinical applications.

A Case-Based Guide to Neuromuscular Pathology

Author : Lan Zhou
Publisher : Springer Nature
ISBN 13 : 3030256820
Total Pages : 408 pages
Book Rating : 4.0/5 (32 download)

DOWNLOAD NOW!

Book Synopsis A Case-Based Guide to Neuromuscular Pathology by : Lan Zhou

Download or read book A Case-Based Guide to Neuromuscular Pathology written by Lan Zhou and published by Springer Nature. This book was released on 2019-10-24 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a practical guide to the field of neuromuscular pathology including muscle, peripheral nerve, and skin biopsies with biopsy interpretation. Divided into three parts, the book begins with introductory chapters that review muscle, nerve, and skin biopsy indications and procedures, normal muscle and nerve histology, and common muscle and nerve pathology. The 28 myopathy case chapters in Part 2 and 11 neuropathy case chapters in Part 3 illustrate the clinical and pathological features of many neuromuscular diseases, demonstrate the indications and utilities of biopsies, discuss clinical and pathological differential diagnosis, update the individual disease management, and summarize pertinent clinical and pathology pearls for each case. A Case-Based Guide to Neuromuscular Pathology will function as an indispensable reference for neurologists and pathologists looking to understand the utility of muscle, nerve, and skin biopsies. This book will also aid neurology residents, neuromuscular fellows and neuropathology fellows in preparing for questions related to the muscle and nerve pathology in their in-service and board exams.

Applied Cardiovascular Physiology

Author : Michael Pinsky
Publisher : Springer Science & Business Media
ISBN 13 : 3642606962
Total Pages : 405 pages
Book Rating : 4.6/5 (426 download)

DOWNLOAD NOW!

Book Synopsis Applied Cardiovascular Physiology by : Michael Pinsky

Download or read book Applied Cardiovascular Physiology written by Michael Pinsky and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise yet complete overview of the treatment of cardiovascular instability in the critically ill patient. The authors consider all aspects, ranging from basic physiology and pathophysiology to diagnostic tools and established and novel forms of therapy. The whole is rounded off with an integration of these principles into a series of clinically relevant scenarios.