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Effective Optimization Algorithms For Fragment Assembly Based Protein Structure Prediction
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Book Synopsis Computational Systems Bioinformatics - Proceedings Of The Conference Csb 2006 by : Peter Markstein
Download or read book Computational Systems Bioinformatics - Proceedings Of The Conference Csb 2006 written by Peter Markstein and published by World Scientific. This book was released on 2006-07-28 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains about 40 papers covering many of the latest developments in the fast-growing field of bioinformatics. The contributions span a wide range of topics, including computational genomics and genetics, protein function and computational proteomics, the transcriptome, structural bioinformatics, microarray data analysis, motif identification, biological pathways and systems, and biomedical applications. There are also abstracts from the keynote addresses and invited talks.The papers cover not only theoretical aspects of bioinformatics but also delve into the application of new methods, with input from computation, engineering and biology disciplines. This multidisciplinary approach to bioinformatics gives these proceedings a unique viewpoint of the field./a
Book Synopsis Computational Systems Bioinformatics by : Peter Markstein
Download or read book Computational Systems Bioinformatics written by Peter Markstein and published by Imperial College Press. This book was released on 2006 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains about 40 papers covering many of the latest developments in the fast-growing field of bioinformatics. The contributions span a wide range of topics, including computational genomics and genetics, protein function and computational proteomics, the transcriptome, structural bioinformatics, microarray data analysis, motif identification, biological pathways and systems, and biomedical applications. There are also abstracts from the keynote addresses and invited talks. The papers cover not only theoretical aspects of bioinformatics but also delve into the application of new methods, with input from computation, engineering and biology disciplines. This multidisciplinary approach to bioinformatics gives these proceedings a unique viewpoint of the field. Sample Chapter(s). Chapter 1: Exploring the Ocean''s Microbes: Sequencing the Seven Seas (122 KB). Contents: Exploring the Ocean''s Microbes: Sequencing the Seven Seas (M E Frazier et al.); Protein Network Comparative Genomics (T Ideker); Bioinformatics at Microsoft Research (S Mercer); Protein Fold Recognition Using Gradient Boost Algorithm (F Jiao et al.); Efficient Annotation of Non-Coding RNA Structures Including Pseudoknots via Automated Filters (C Liu et al.); Efficient Generalized Matrix Approximations for Biomarker Discovery and Visualization in Gene Expression Data (W Li et al.); Sorting Genomes by Translocations and Deletions (X Qi et al.); Detection of Cleavage Sites for HIV-1 Protease in Native Proteins (L You); Identifying Biological Pathways via Phase Decomposition and Profile Extraction (Y Zhang & Z Deng); Complexity and Scoring Function of MS/MS Peptide De Novo Sequencing (C Xu & B Ma); Simulating In Vitro Epithelial Morphogenesis in Multiple Environments (M R Grant et al.); and other papers. Readership: Research and application community in bioinformatics, systems biology, medicine, pharmacology and biotechnology. A useful reference for graduate researchers in bioinformatics and computational biology.
Book Synopsis Computational Methods for Protein Structure Prediction and Modeling by : Ying Xu
Download or read book Computational Methods for Protein Structure Prediction and Modeling written by Ying Xu and published by Springer Science & Business Media. This book was released on 2010-05-05 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume Two of this two-volume sequence presents a comprehensive overview of protein structure prediction methods and includes protein threading, De novo methods, applications to membrane proteins and protein complexes, structure-based drug design, as well as structure prediction as a systems problem. A series of appendices review the biological and chemical basics related to protein structure, computer science for structural informatics, and prerequisite mathematics and statistics.
Book Synopsis Journal of the Royal Society Interface by :
Download or read book Journal of the Royal Society Interface written by and published by . This book was released on 2008 with total page 734 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Constrained Optimization and Lagrange Multiplier Methods by : Dimitri P. Bertsekas
Download or read book Constrained Optimization and Lagrange Multiplier Methods written by Dimitri P. Bertsekas and published by Academic Press. This book was released on 2014-05-10 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computer Science and Applied Mathematics: Constrained Optimization and Lagrange Multiplier Methods focuses on the advancements in the applications of the Lagrange multiplier methods for constrained minimization. The publication first offers information on the method of multipliers for equality constrained problems and the method of multipliers for inequality constrained and nondifferentiable optimization problems. Discussions focus on approximation procedures for nondifferentiable and ill-conditioned optimization problems; asymptotically exact minimization in the methods of multipliers; duality framework for the method of multipliers; and the quadratic penalty function method. The text then examines exact penalty methods, including nondifferentiable exact penalty functions; linearization algorithms based on nondifferentiable exact penalty functions; differentiable exact penalty functions; and local and global convergence of Lagrangian methods. The book ponders on the nonquadratic penalty functions of convex programming. Topics include large scale separable integer programming problems and the exponential method of multipliers; classes of penalty functions and corresponding methods of multipliers; and convergence analysis of multiplier methods. The text is a valuable reference for mathematicians and researchers interested in the Lagrange multiplier methods.
Book Synopsis Application of Advanced Optimization Techniques for Healthcare Analytics by : Mohamed Abdel-Basset
Download or read book Application of Advanced Optimization Techniques for Healthcare Analytics written by Mohamed Abdel-Basset and published by CRC Press. This book was released on 2023-04-11 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: Application of Advanced Optimization Techniques for Healthcare Analytics, 1st Edition, is an excellent compilation of current and advanced optimization techniques which can readily be applied to solve different hospital management problems. The healthcare system is currently a topic of significant investigation to make life easier for those who are disabled, old, or sick, as well as for young children. The emphasis of the healthcare system has evolved throughout time due to several emerging beneficial technologies, such as personal digital assistants (PDAs), data mining, the internet of things, metaheuristics, fog computing, and cloud computing. Metaheuristics are strong technology for tackling several optimization problems in various fields, especially healthcare systems. The primary advantage of metaheuristic algorithms is their ability to find a better solution to a healthcare problem and their ability to consume as little time as possible. In addition, metaheuristics are more flexible compared to several other optimization techniques. These algorithms are not related to a specific optimization problem but could be applied to any optimization problem by making some small adaptations to become suitable to tackle it. The successful outcome of this book will enable a decision-maker or practitioner to pick a suitable optimization approach when making decisions to schedule patients under crowding environments with minimized human errors.
Book Synopsis Prediction of Protein Structures, Functions, and Interactions by : Janusz M. Bujnicki
Download or read book Prediction of Protein Structures, Functions, and Interactions written by Janusz M. Bujnicki and published by John Wiley & Sons. This book was released on 2008-12-23 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: The growing flood of new experimental data generated by genome sequencing has provided an impetus for the development of automated methods for predicting the functions of proteins that have been deduced by sequence analysis and lack experimental characterization. Prediction of Protein Structures, Functions and Interactions presents a comprehensive overview of methods for prediction of protein structure or function, with the emphasis on their availability and possibilities for their combined use. Methods of modeling of individual proteins, prediction of their interactions, and docking of complexes are put in the context of predicting gene ontology (biological process, molecular function, and cellular component) and discussed in the light of their contribution to the emerging field of systems biology. Topics covered include: first steps of protein sequence analysis and structure prediction automated prediction of protein function from sequence template-based prediction of three-dimensional protein structures: fold-recognition and comparative modelling template-free prediction of three-dimensional protein structures quality assessment of protein models prediction of molecular interactions: from small ligands to large protein complexes macromolecular docking integrating prediction of structure, function, and interactions Prediction of Protein Structures, Functions and Interactions focuses on the methods that have performed well in CASPs, and which are constantly developed and maintained, and are freely available to academic researchers either as web servers or programs for local installation. It is an essential guide to the newest, best methods for prediction of protein structure and functions, for researchers and advanced students working in structural bioinformatics, protein chemistry, structural biology and drug discovery.
Book Synopsis Searching for Molecular Solutions by : Ian S. Dunn
Download or read book Searching for Molecular Solutions written by Ian S. Dunn and published by John Wiley & Sons. This book was released on 2010-01-05 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive look at empirical approaches to molecular discovery, their relationships with rational design, and the future of both Empirical methods of discovery, along with serendipitous and rational design approaches, have played an important role in human history. Searching for Molecular Solutions compares empirical discovery strategies for biologically useful molecules with serendipitous discovery and rational design, while also considering the strengths and limitations of empirical pathways to molecular discovery. Logically arranged, this text examines the different modes of molecular discovery, empha-sizing the historical and ongoing importance of empirical strategies. Along with a broad overview of the subject matter, Searching for Molecular Solutions explores: The differing modes of molecular discovery Biological precedents for evolutionary approaches Directed evolutionary methods and related areas Enzyme evolution and design Functional nucleic acid discovery Antibodies and other recognition molecules General aspects of molecular recognition Small molecule discovery approaches Rational molecular design The interplay between empirical and rational strategies and their ongoing roles in the future of molecular discovery Searching for Molecular Solutions covers several major areas of modern research, development, and practical applications of molecular sciences. This text offers empirical-rational principles of broad relevance to scientists, professionals, and students interested in general aspects of molecular discovery, as well as the thought processes behind experimental approaches.
Book Synopsis Protein-based Therapeutics by : Dev Bukhsh Singh
Download or read book Protein-based Therapeutics written by Dev Bukhsh Singh and published by Springer Nature. This book was released on 2023-03-01 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of the essential characteristics and clinical applications of therapeutic proteins against human diseases, including cancers, immune disorders, infections, and other diseases. It presents the latest advancements in protein engineering techniques for producing desirable therapeutic proteins. The book also covers the strategies used to formulate and deliver systemic therapeutic proteins, approved protein therapeutics and their targets, and pharmacogenetic biomarkers. Further, it discusses challenges associated with the clinical implications of therapeutic proteins, including safety, immunogenicity, protein stability, degradation, and efficacy. It illustrates the development of biosimilar antibodies, optimization strategies for producing biobetter antibodies, and presents fundamental concepts about biosuperior therapeutics. Lastly, it includes a discussion about protein-based vaccines against bacterial and viral infections.
Book Synopsis Computational Science - ICCS 2007 by : Yong Shi
Download or read book Computational Science - ICCS 2007 written by Yong Shi and published by Springer. This book was released on 2007-07-14 with total page 1285 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of a four-volume set, this book constitutes the refereed proceedings of the 7th International Conference on Computational Science, ICCS 2007, held in Beijing, China in May 2007. The papers cover a large volume of topics in computational science and related areas, from multiscale physics to wireless networks, and from graph theory to tools for program development.
Book Synopsis Pacific Symposium on Biocomputing 2004 by : Russ Altman
Download or read book Pacific Symposium on Biocomputing 2004 written by Russ Altman and published by World Scientific. This book was released on 2003 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Pacific Symposium on Biocomputing (PSB 2004) is an international, multidisciplinary conference for the presentation and discussion of current research on the theory and application of computational methods in problems of biological significance. The rigorously peer-reviewed papers and presentations are collected in this archival proceedings volume. PSB is a forum for the presentation of work on databases, algorithms, interfaces, visualization, modeling and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology. PSB 2004 brings together top researchers from the US, the Asia-Pacific region and the rest of the world to exchange research findings and address open issues in all aspects of computational biology. The proceedings have been selected for coverage in: . OCo Biochemistry & Biophysics Citation IndexOao. OCo Index to Scientific & Technical Proceedings- (ISTP- / ISI Proceedings). OCo Index to Scientific & Technical Proceedings (ISTP CDROM version / ISI Proceedings)."
Book Synopsis Biocomputing 2004 - Proceedings Of The Pacific Symposium by : A Keith Dunker
Download or read book Biocomputing 2004 - Proceedings Of The Pacific Symposium written by A Keith Dunker and published by World Scientific. This book was released on 2003-12-12 with total page 611 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Pacific Symposium on Biocomputing (PSB 2004) is an international, multidisciplinary conference for the presentation and discussion of current research on the theory and application of computational methods in problems of biological significance. The rigorously peer-reviewed papers and presentations are collected in this archival proceedings volume.PSB is a forum for the presentation of work on databases, algorithms, interfaces, visualization, modeling and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology. PSB 2004 brings together top researchers from the US, the Asia-Pacific region and the rest of the world to exchange research findings and address open issues in all aspects of computational biology.The proceedings have been selected for coverage in:
Book Synopsis Harmony Search and Nature Inspired Optimization Algorithms by : Neha Yadav
Download or read book Harmony Search and Nature Inspired Optimization Algorithms written by Neha Yadav and published by Springer. This book was released on 2018-08-23 with total page 1209 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book covers different aspects of real-world applications of optimization algorithms. It provides insights from the Fourth International Conference on Harmony Search, Soft Computing and Applications held at BML Munjal University, Gurgaon, India on February 7–9, 2018. It consists of research articles on novel and newly proposed optimization algorithms; the theoretical study of nature-inspired optimization algorithms; numerically established results of nature-inspired optimization algorithms; and real-world applications of optimization algorithms and synthetic benchmarking of optimization algorithms.
Book Synopsis The Journal of the Korean Physical Society by :
Download or read book The Journal of the Korean Physical Society written by and published by . This book was released on 2008 with total page 1020 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Optimization Techniques for Solving Complex Problems by : Enrique Alba
Download or read book Optimization Techniques for Solving Complex Problems written by Enrique Alba and published by John Wiley & Sons. This book was released on 2009-02-17 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Real-world problems and modern optimization techniques to solve them Here, a team of international experts brings together core ideas for solving complex problems in optimization across a wide variety of real-world settings, including computer science, engineering, transportation, telecommunications, and bioinformatics. Part One—covers methodologies for complex problem solving including genetic programming, neural networks, genetic algorithms, hybrid evolutionary algorithms, and more. Part Two—delves into applications including DNA sequencing and reconstruction, location of antennae in telecommunication networks, metaheuristics, FPGAs, problems arising in telecommunication networks, image processing, time series prediction, and more. All chapters contain examples that illustrate the applications themselves as well as the actual performance of the algorithms.?Optimization Techniques for Solving Complex Problems is a valuable resource for practitioners and researchers who work with optimization in real-world settings.
Book Synopsis Computational Protein Design by : Ilan Samish
Download or read book Computational Protein Design written by Ilan Samish and published by Humana. This book was released on 2016-12-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim this volume is to present the methods, challenges, software, and applications of this widespread and yet still evolving and maturing field. Computational Protein Design, the first book with this title, guides readers through computational protein design approaches, software and tailored solutions to specific case-study targets. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Computational Protein Design aims to ensure successful results in the further study of this vital field.
Book Synopsis Computational Structural Biology by : Torsten Schwede
Download or read book Computational Structural Biology written by Torsten Schwede and published by World Scientific. This book was released on 2008 with total page 790 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive introduction to Landau-Lifshitz equations and Landau-Lifshitz-Maxwell equations, beginning with the work by Yulin Zhou and Boling Guo in the early 1980s and including most of the work done by this Chinese group led by Zhou and Guo since. The book focuses on aspects such as the existence of weak solutions in multi dimensions, existence and uniqueness of smooth solutions in one dimension, relations with harmonic map heat flows, partial regularity and long time behaviors. The book is a valuable reference book for those who are interested in partial differential equations, geometric analysis and mathematical physics. It may also be used as an advanced textbook by graduate students in these fields.
