Author : Dulmelis Gonzalez
Publisher :
ISBN 13 :
Total Pages : 222 pages
Book Rating : 4.:/5 (3 download)
Book Synopsis Effect of Dietary Fatty Acids, Time of Feeding and Immune Response in Poultry by : Dulmelis Gonzalez
Download or read book Effect of Dietary Fatty Acids, Time of Feeding and Immune Response in Poultry written by Dulmelis Gonzalez and published by . This book was released on 2008 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the presence of internal or external stressors, the body requires sources of energy that aide cells to combat inflammation. Fatty acids are an important source of energy and are vital components of cell membranes. Dietary fatty acids (n-6 and n-3) are of importance in immune function because they are precursors to metabolites that are potent mediators of inflammation. Poultry diets are high in n-6 fatty acids, which exert pro-inflammatory effects, and low in n-3 fatty acids, which tend to be less inflammatory. Delayed access to feed after hatching has been reported to impact the development of organs associated with immunity. Based on this information, two experiments were conducted in broiler chickens to determine the effect of dietary polyunsaturated fatty acid (PUFA) and the influence of time of feeding on bird performance, tissue lipid status, immune responses and expression of cyclooxygenase 2 (COX-2) upon challenge. In experiment 1, birds were fed diets that contained 3.5% oxidized yellow grease (low n-3) or 3.5% canola oil (high n-3). Birds were fed early (5 hrs post-hatch) or late (24 hrs post-hatch). Intramuscular injection of lipopolysaccharide (LPS) or phosphate buffered saline (control) was used as the immune challenge. Feeding high n-3 diets resulted in an increase in n-3 fatty acids in the liver in all treatment groups upon LPS challenge (P0.05). LPS injection led to a decrease in total n-6 fatty acids in the liver when compared with control birds (P0.05) fed early high n-3 and late low n-3. However, in spleen tissue, upon LPS challenge, increase in total n-3 fatty acids was observed only in birds fed early high n-3 and birds fed late high n-3. Plasma non-esterified fatty acids were lowest in high n-3 birds fed early (P0.05). The spleen tissue total fat content was lowest in early high and late high n-3 birds (P0.05). Breast muscle thiobarbituric acid reactive substances (TBARS) were higher in birds fed high n-3 compared to birds fed diets low in n-3 (P
