Sleep Disorders and Sleep Deprivation

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Author :
Publisher : National Academies Press
ISBN 13 : 0309101115
Total Pages : 425 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Sleep Disorders and Sleep Deprivation by : Institute of Medicine

Download or read book Sleep Disorders and Sleep Deprivation written by Institute of Medicine and published by National Academies Press. This book was released on 2006-10-13 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical practice related to sleep problems and sleep disorders has been expanding rapidly in the last few years, but scientific research is not keeping pace. Sleep apnea, insomnia, and restless legs syndrome are three examples of very common disorders for which we have little biological information. This new book cuts across a variety of medical disciplines such as neurology, pulmonology, pediatrics, internal medicine, psychiatry, psychology, otolaryngology, and nursing, as well as other medical practices with an interest in the management of sleep pathology. This area of research is not limited to very young and old patientsâ€"sleep disorders reach across all ages and ethnicities. Sleep Disorders and Sleep Deprivation presents a structured analysis that explores the following: Improving awareness among the general public and health care professionals. Increasing investment in interdisciplinary somnology and sleep medicine research training and mentoring activities. Validating and developing new and existing technologies for diagnosis and treatment. This book will be of interest to those looking to learn more about the enormous public health burden of sleep disorders and sleep deprivation and the strikingly limited capacity of the health care enterprise to identify and treat the majority of individuals suffering from sleep problems.

Sleep-Wake Disorders

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9780306457715
Total Pages : 232 pages
Book Rating : 4.4/5 (577 download)

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Book Synopsis Sleep-Wake Disorders by : K. Meier-Ewert

Download or read book Sleep-Wake Disorders written by K. Meier-Ewert and published by Springer Science & Business Media. This book was released on 1997 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of a Japanese-German International Symposium held in Erfurt, Germany, October 9-10, 1996

The ASAM Principles of Addiction Medicine

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Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1496371003
Total Pages : 1984 pages
Book Rating : 4.4/5 (963 download)

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Book Synopsis The ASAM Principles of Addiction Medicine by : Shannon Miller

Download or read book The ASAM Principles of Addiction Medicine written by Shannon Miller and published by Lippincott Williams & Wilkins. This book was released on 2018-11-26 with total page 1984 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Thoroughly updated with the latest international evidence-based research and best practices, the comprehensive sixth edition of the American Society of Addiction Medicine’s (ASAM) official flagship textbook reviews the science and art behind addiction medicine and provides health care providers with the necessary information to not only properly diagnose and treat their patients, but to also serve as change agents to positively impact clinical service design and delivery, as well as global health care policy.

Why We Sleep

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Publisher : Simon and Schuster
ISBN 13 : 1501144316
Total Pages : 368 pages
Book Rating : 4.5/5 (11 download)

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Book Synopsis Why We Sleep by : Matthew Walker

Download or read book Why We Sleep written by Matthew Walker and published by Simon and Schuster. This book was released on 2017-10-03 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Sleep is one of the most important but least understood aspects of our life, wellness, and longevity ... An explosion of scientific discoveries in the last twenty years has shed new light on this fundamental aspect of our lives. Now ... neuroscientist and sleep expert Matthew Walker gives us a new understanding of the vital importance of sleep and dreaming"--Amazon.com.

The Craving Mind

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Publisher : Yale University Press
ISBN 13 : 0300227604
Total Pages : 227 pages
Book Rating : 4.3/5 (2 download)

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Book Synopsis The Craving Mind by : Judson Brewer

Download or read book The Craving Mind written by Judson Brewer and published by Yale University Press. This book was released on 2017-03-07 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: A leading neuroscientist and pioneer in the study of mindfulness explains why addictions are so tenacious and how we can learn to conquer them We are all vulnerable to addiction. Whether it’s a compulsion to constantly check social media, binge eating, smoking, excessive drinking, or any other behaviors, we may find ourselves uncontrollably repeating. Why are bad habits so hard to overcome? Is there a key to conquering the cravings we know are unhealthy for us? This book provides groundbreaking answers to the most important questions about addiction. Dr. Judson Brewer, a psychiatrist and neuroscientist who has studied the science of addictions for twenty years, reveals how we can tap into the very processes that encourage addictive behaviors in order to step out of them. He describes the mechanisms of habit and addiction formation, then explains how the practice of mindfulness can interrupt these habits. Weaving together patient stories, his own experience with mindfulness practice, and current scientific findings from his own lab and others, Dr. Brewer offers a path for moving beyond our cravings, reducing stress, and ultimately living a fuller life.

Magnesium in the Central Nervous System

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Publisher : University of Adelaide Press
ISBN 13 : 0987073052
Total Pages : 354 pages
Book Rating : 4.9/5 (87 download)

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Book Synopsis Magnesium in the Central Nervous System by : Robert Vink

Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Dopamine Nation

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Publisher : Penguin
ISBN 13 : 1524746746
Total Pages : 305 pages
Book Rating : 4.5/5 (247 download)

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Book Synopsis Dopamine Nation by : Dr. Anna Lembke

Download or read book Dopamine Nation written by Dr. Anna Lembke and published by Penguin. This book was released on 2023-01-03 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: INSTANT NEW YORK TIMES and LOS ANGELES TIMES BESTSELLER “Brilliant . . . riveting, scary, cogent, and cleverly argued.”—Beth Macy, author of Dopesick, as heard on Fresh Air This book is about pleasure. It’s also about pain. Most important, it’s about how to find the delicate balance between the two, and why now more than ever finding balance is essential. We’re living in a time of unprecedented access to high-reward, high-dopamine stimuli: drugs, food, news, gambling, shopping, gaming, texting, sexting, Facebooking, Instagramming, YouTubing, tweeting . . . The increased numbers, variety, and potency is staggering. The smartphone is the modern-day hypodermic needle, delivering digital dopamine 24/7 for a wired generation. As such we’ve all become vulnerable to compulsive overconsumption. In Dopamine Nation, Dr. Anna Lembke, psychiatrist and author, explores the exciting new scientific discoveries that explain why the relentless pursuit of pleasure leads to pain . . . and what to do about it. Condensing complex neuroscience into easy-to-understand metaphors, Lembke illustrates how finding contentment and connectedness means keeping dopamine in check. The lived experiences of her patients are the gripping fabric of her narrative. Their riveting stories of suffering and redemption give us all hope for managing our consumption and transforming our lives. In essence, Dopamine Nation shows that the secret to finding balance is combining the science of desire with the wisdom of recovery.

Addiction

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Author :
Publisher : Routledge
ISBN 13 : 1317684745
Total Pages : 308 pages
Book Rating : 4.3/5 (176 download)

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Book Synopsis Addiction by : Shahram Heshmat

Download or read book Addiction written by Shahram Heshmat and published by Routledge. This book was released on 2015-05-22 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addiction: A Behavioral Economic Perspective focuses on the behavioral economics of addiction to explain why someone decides and act against her own well-being. It answers the questions of what accounts for self-defeating behavior patterns and how do we best motivate individuals to act according with their long-term goals. A better understanding of decision processes will lead to an improved knowledge of why people engage in self-destructive behaviors and better policy interventions in areas of addiction and obesity. The approach also promises to be valuable as a framework for understanding decisions for an addict’s professional and business life. This book will be of particular use to clinicians, students, and researchers in the fields of addiction, public health, and behavior therapy.

Substance and Non-substance Addiction

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Publisher : Springer
ISBN 13 : 9811055629
Total Pages : 357 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Substance and Non-substance Addiction by : Xiaochu Zhang

Download or read book Substance and Non-substance Addiction written by Xiaochu Zhang and published by Springer. This book was released on 2017-11-02 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the similarities and differences between substance and non-substance addictions. It discusses in detail the mechanisms, diagnosis and treatment of substance and non-substance addictions, and addresses selected prospects that will shape future studies on addiction. Addiction is a global problem that costs millions of lives tremendous damage year after year. There are mainly two types of addition: substance addiction (e.g., nicotine, alcohol, cannabis, heroin, stimulants, etc.) and non-substance addiction (e.g., gambling, computer gaming, Internet, etc.). Based on existing evidence, both types of addiction produce negative impacts on individuals’ physical, mental, social and financial well-being, and share certain common mechanisms, which involve a dysfunction of the neural reward system and specific gene transcription factors. However, there are also key differences between these two types of addiction. Covering these aspects systematically, the book will provide researchers and graduate students alike a better understanding of drug and behavioral addictions.

Bright Line Eating

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Author :
Publisher : Hay House, Inc
ISBN 13 : 1401952550
Total Pages : 322 pages
Book Rating : 4.4/5 (19 download)

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Book Synopsis Bright Line Eating by : Susan Peirce Thompson, PHD

Download or read book Bright Line Eating written by Susan Peirce Thompson, PHD and published by Hay House, Inc. This book was released on 2021-01-05 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: A NEW YORK TIMES BESTSELLER Foreword by John Robbins, author of the international bestseller Diet for A New America In this book, Susan Peirce Thompson, Ph.D. shares the groundbreaking weight-loss solution based on her highly acclaimed Bright Line Eating Boot Camps. Rooted in cutting-edge neuroscience, psychology, and biology, Bright Line Eating explains why people who are desperate to lose weight fail again and again: it’s because the brain blocks weight loss. Bright Line Eating (BLE) is a simple approach designed to reverse that process. By working with four "Bright Lines"—clear, unambiguous, boundaries—Susan Peirce Thompson shows us how to heal our brain and shift it into a mode where it is ready to shed pounds, release cravings, and stop sabotaging our weight loss goals.Best of all, it is a program that understands that willpower cannot be relied on, and sets us up to be successful anyway. Through the lens of Susan’s own moving story, and those of her Bright Lifers, you’ll discover firsthand why traditional diet and exercise plans have failed in the past. You’ll also learn about the role addictive susceptibility plays in your personal weight-loss journey, where cravings come from, how to rewire your brain so they disappear, and more. Susan guides you through the phases of Bright Line Eating—from weight loss to maintenance and beyond—and offers a dynamic food plan that will work for anyone, whether you’re vegan, gluten-free, paleo, or none of the above. Bright Line Eating frees us from the obesity cycle and introduces a radical plan for sustainable weight loss. It’s a game changer in a game that desperately needs changing.

Opium Fiend

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Publisher : Villard
ISBN 13 : 0345517857
Total Pages : 417 pages
Book Rating : 4.3/5 (455 download)

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Book Synopsis Opium Fiend by : Steven Martin

Download or read book Opium Fiend written by Steven Martin and published by Villard. This book was released on 2012-06-26 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: NEW YORK TIMES BESTSELLER A renowned authority on the secret world of opium recounts his descent into ruinous obsession with one of the world’s oldest and most seductive drugs, in this harrowing memoir of addiction and recovery. A natural-born collector with a nose for exotic adventure, San Diego–born Steven Martin followed his bliss to Southeast Asia, where he found work as a freelance journalist. While researching an article about the vanishing culture of opium smoking, he was inspired to begin collecting rare nineteenth-century opium-smoking equipment. Over time, he amassed a valuable assortment of exquisite pipes, antique lamps, and other opium-related accessories—and began putting it all to use by smoking an extremely potent form of the drug called chandu. But what started out as recreational use grew into a thirty-pipe-a-day habit that consumed Martin’s every waking hour, left him incapable of work, and exacted a frightful physical and financial toll. In passages that will send a chill up the spine of anyone who has ever lived in the shadow of substance abuse, Martin chronicles his efforts to control and then conquer his addiction—from quitting cold turkey to taking “the cure” at a Buddhist monastery in the Thai countryside. At once a powerful personal story and a fascinating historical survey, Opium Fiend brims with anecdotes and lore surrounding the drug that some have called the methamphetamine of the nineteenth-century. It recalls the heyday of opium smoking in the United States and Europe and takes us inside the befogged opium dens of China, Thailand, Vietnam, and Laos. The drug’s beguiling effects are described in vivid detail—as are the excruciating pains of withdrawal—and there are intoxicating tales of pipes shared with an eclectic collection of opium aficionados, from Dutch dilettantes to hard-core addicts to world-weary foreign correspondents. A compelling tale of one man’s transformation from respected scholar to hapless drug slave, Opium Fiend puts us under opium’s spell alongside its protagonist, allowing contemporary readers to experience anew the insidious allure of a diabolical vice that the world has all but forgotten.

Not Eating Enough

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Author :
Publisher : National Academies Press
ISBN 13 : 0309053412
Total Pages : 498 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Not Eating Enough by : Institute of Medicine

Download or read book Not Eating Enough written by Institute of Medicine and published by National Academies Press. This book was released on 1995-10-01 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eating enough food to meet nutritional needs and maintain good health and good performance in all aspects of lifeâ€"both at home and on the jobâ€"is important for all of us throughout our lives. For military personnel, however, this presents a special challenge. Although soldiers typically have a number of options for eating when stationed on a base, in the field during missions their meals come in the form of operational rations. Unfortunately, military personnel in training and field operations often do not eat their rations in the amounts needed to ensure that they meet their energy and nutrient requirements and consequently lose weight and potentially risk loss of effectiveness both in physical and cognitive performance. This book contains 20 chapters by military and nonmilitary scientists from such fields as food science, food marketing and engineering, nutrition, physiology, psychology, and various medical specialties. Although described within a context of military tasks, the committee's conclusions and recommendations have wide-reaching implications for people who find that job-related stress changes their eating habits.

The Molecule of More

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Publisher : BenBella Books
ISBN 13 : 1946885290
Total Pages : 240 pages
Book Rating : 4.9/5 (468 download)

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Book Synopsis The Molecule of More by : Daniel Z. Lieberman

Download or read book The Molecule of More written by Daniel Z. Lieberman and published by BenBella Books. This book was released on 2018-08-14 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why are we obsessed with the things we want only to be bored when we get them? Why is addiction perfectly logical to an addict? Why does love change so quickly from passion to indifference? Why are some people die-hard liberals and others hardcore conservatives? Why are we always hopeful for solutions even in the darkest times—and so good at figuring them out? The answer is found in a single chemical in your brain: dopamine. Dopamine ensured the survival of early man. Thousands of years later, it is the source of our most basic behaviors and cultural ideas—and progress itself. Dopamine is the chemical of desire that always asks for more—more stuff, more stimulation, and more surprises. In pursuit of these things, it is undeterred by emotion, fear, or morality. Dopamine is the source of our every urge, that little bit of biology that makes an ambitious business professional sacrifice everything in pursuit of success, or that drives a satisfied spouse to risk it all for the thrill of someone new. Simply put, it is why we seek and succeed; it is why we discover and prosper. Yet, at the same time, it's why we gamble and squander. From dopamine's point of view, it's not the having that matters. It's getting something—anything—that's new. From this understanding—the difference between possessing something versus anticipating it—we can understand in a revolutionary new way why we behave as we do in love, business, addiction, politics, religion—and we can even predict those behaviors in ourselves and others. In The Molecule of More: How a Single Chemical in Your Brain Drives Love, Sex, and Creativity—and will Determine the Fate of the Human Race, George Washington University professor and psychiatrist Daniel Z. Lieberman, MD, and Georgetown University lecturer Michael E. Long present a potentially life-changing proposal: Much of human life has an unconsidered component that explains an array of behaviors previously thought to be unrelated, including why winners cheat, why geniuses often suffer with mental illness, why nearly all diets fail, and why the brains of liberals and conservatives really are different.

Still Alive

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Author :
Publisher : AuthorHouse
ISBN 13 : 1468500163
Total Pages : 351 pages
Book Rating : 4.4/5 (685 download)

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Book Synopsis Still Alive by : Rusty Lee

Download or read book Still Alive written by Rusty Lee and published by AuthorHouse. This book was released on 2011-12-07 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Im quite certain that before you fi nish this book, you will not like me. I do not fl atter myself for I have discovered looking back on my life, I made many poor decisions. Nevertheless, Ive been told by many is that war veterans, addicts and those who face deadly disease and those who have lost all hope can benefi t from what Ive learned. You, my friends, like I continue striving to do, can persevere even when it seems the road before you leads to nothingness.

Hooked

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Publisher : Random House
ISBN 13 : 0812997301
Total Pages : 278 pages
Book Rating : 4.8/5 (129 download)

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Book Synopsis Hooked by : Michael Moss

Download or read book Hooked written by Michael Moss and published by Random House. This book was released on 2021-03-02 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: NEW YORK TIMES BESTSELLER • From the author of Salt Sugar Fat comes a “gripping” (The Wall Street Journal) exposé of how the processed food industry exploits our evolutionary instincts, the emotions we associate with food, and legal loopholes in their pursuit of profit over public health. “The processed food industry has managed to avoid being lumped in with Big Tobacco—which is why Michael Moss’s new book is so important.”—Charles Duhigg, author of The Power of Habit Everyone knows how hard it can be to maintain a healthy diet. But what if some of the decisions we make about what to eat are beyond our control? Is it possible that food is addictive, like drugs or alcohol? And to what extent does the food industry know, or care, about these vulnerabilities? In Hooked, Pulitzer Prize–winning investigative reporter Michael Moss sets out to answer these questions—and to find the true peril in our food. Moss uses the latest research on addiction to uncover what the scientific and medical communities—as well as food manufacturers—already know: that food, in some cases, is even more addictive than alcohol, cigarettes, and drugs. Our bodies are hardwired for sweets, so food giants have developed fifty-six types of sugar to add to their products, creating in us the expectation that everything should be cloying; we’ve evolved to prefer fast, convenient meals, hence our modern-day preference for ready-to-eat foods. Moss goes on to show how the processed food industry—including major companies like Nestlé, Mars, and Kellogg’s—has tried not only to evade this troubling discovery about the addictiveness of food but to actually exploit it. For instance, in response to recent dieting trends, food manufacturers have simply turned junk food into junk diets, filling grocery stores with “diet” foods that are hardly distinguishable from the products that got us into trouble in the first place. As obesity rates continue to climb, manufacturers are now claiming to add ingredients that can effortlessly cure our compulsive eating habits. A gripping account of the legal battles, insidious marketing campaigns, and cutting-edge food science that have brought us to our current public health crisis, Hooked lays out all that the food industry is doing to exploit and deepen our addictions, and shows us why what we eat has never mattered more.

Not Weakness

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Author :
Publisher : Simon and Schuster
ISBN 13 : 164742478X
Total Pages : 130 pages
Book Rating : 4.6/5 (474 download)

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Book Synopsis Not Weakness by : Francesca Grossman

Download or read book Not Weakness written by Francesca Grossman and published by Simon and Schuster. This book was released on 2023-04-18 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: After thyroid cancer, Crohn’s disease, and a slew of other autoimmune conditions ransacked her body in her twenties and thirties, Francesca was left feeling completely alone in her chronic pain. Constant, relentless, often indescribable, and always exhausting, it affected her whole life—intimacy, motherhood, friendship, work, and mental health. Yet it was also fairly invisible—and because of that, Francesca felt entirely alone in the centrifuge of her own pain. But after twenty-plus years of living this way, isolated and depressed, she started to wonder: if she lived in pain, others must too—so why couldn't she name one person in her community who suffered like she did? On a whim, Francesca started asking women in her community if they had chronic pain—only to find that she was surrounded by women also battling in silence. The more she spoke to people, the more she found common themes and experiences, proving that her stories of pain were not unique, and neither were her feelings of loneliness and seclusion. Liberated by this discovery, Francesca realized something: while she couldn’t alleviate anyone's pain, maybe she could lift the shadows surrounding it—bring these common stories into the light, with the goal of helping her fellow chronic pain sufferers feel a little less alone. Imbued with a deep respect for the women who tell their stories in its pages, as well as a healthy skepticism of the healthcare world and how it can silence, shame, and ignore women in pain, Not Weakness is galvanizing memoir about living and loving with chronic pain.

The Health Effects of Cannabis and Cannabinoids

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Author :
Publisher : National Academies Press
ISBN 13 : 0309453070
Total Pages : 487 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis The Health Effects of Cannabis and Cannabinoids by : National Academies of Sciences, Engineering, and Medicine

Download or read book The Health Effects of Cannabis and Cannabinoids written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-03-31 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significant changes have taken place in the policy landscape surrounding cannabis legalization, production, and use. During the past 20 years, 25 states and the District of Columbia have legalized cannabis and/or cannabidiol (a component of cannabis) for medical conditions or retail sales at the state level and 4 states have legalized both the medical and recreational use of cannabis. These landmark changes in policy have impacted cannabis use patterns and perceived levels of risk. However, despite this changing landscape, evidence regarding the short- and long-term health effects of cannabis use remains elusive. While a myriad of studies have examined cannabis use in all its various forms, often these research conclusions are not appropriately synthesized, translated for, or communicated to policy makers, health care providers, state health officials, or other stakeholders who have been charged with influencing and enacting policies, procedures, and laws related to cannabis use. Unlike other controlled substances such as alcohol or tobacco, no accepted standards for safe use or appropriate dose are available to help guide individuals as they make choices regarding the issues of if, when, where, and how to use cannabis safely and, in regard to therapeutic uses, effectively. Shifting public sentiment, conflicting and impeded scientific research, and legislative battles have fueled the debate about what, if any, harms or benefits can be attributed to the use of cannabis or its derivatives, and this lack of aggregated knowledge has broad public health implications. The Health Effects of Cannabis and Cannabinoids provides a comprehensive review of scientific evidence related to the health effects and potential therapeutic benefits of cannabis. This report provides a research agendaâ€"outlining gaps in current knowledge and opportunities for providing additional insight into these issuesâ€"that summarizes and prioritizes pressing research needs.