Early Indicators of Cognitive Decline, Alzheimer’s Disease, and Related Dementias Captured by Neurophysiological Tools

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2832548148
Total Pages : 177 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Early Indicators of Cognitive Decline, Alzheimer’s Disease, and Related Dementias Captured by Neurophysiological Tools by : Alexandra Wolf

Download or read book Early Indicators of Cognitive Decline, Alzheimer’s Disease, and Related Dementias Captured by Neurophysiological Tools written by Alexandra Wolf and published by Frontiers Media SA. This book was released on 2024-04-19 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: Major neurocognitive disorders are one of the leading causes of disability and dependency among the elderly worldwide. Notably, their far-reaching impact extends beyond the estimated 50 million people currently living with a major neurocognitive disorder. As the conversion to Alzheimer's disease (AD) progresses, patients’ symptoms (e.g., memory loss, severe impairments in thinking and behavior) place a heavy toll on their caregivers, family, and friends, who face emotional frustration, coupled with great financial stress. Furthermore, in terms of global cost estimation, the World Health Organization predicted that by 2030, the treatment of patients with AD and other forms of acquired cognitive impairment will cost the healthcare system US$1.7 trillion (or US$2.8 trillion, if corrected for the increase in care costs).

Recognition and Initial Assessment of Alzheimer's Disease and Related Dementias

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Publisher :
ISBN 13 :
Total Pages : 156 pages
Book Rating : 4.:/5 (327 download)

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Book Synopsis Recognition and Initial Assessment of Alzheimer's Disease and Related Dementias by :

Download or read book Recognition and Initial Assessment of Alzheimer's Disease and Related Dementias written by and published by . This book was released on 1996 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dementia in the adult U.S. population is a devastating disorder that is often unrecognized or misdiagnosed in its early stages. Despite the current lack of unequivocally effective treatment, recognition of early-stage dementia may offer substantial benefits. These include avoidance of inappropriate treatment related to misdiagnosis and time for the patient and family to address issues of financial, legal, and medical care planning. This Clinical Practice Guideline is intended to help primary care providers recognize and assess Alzheimer's disease and related dementias in the early stages. Differential diagnosis is beyond the scope of the guideline; however, the guidline contains a list of resources for further clinical evaluation once probable dementia has been identified.

Recognition and Initial Assessment of Alzheimer's Disease and Related Dementias

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Publisher :
ISBN 13 :
Total Pages : 158 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Recognition and Initial Assessment of Alzheimer's Disease and Related Dementias by :

Download or read book Recognition and Initial Assessment of Alzheimer's Disease and Related Dementias written by and published by . This book was released on 1996 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dementia in the adult U.S. population is a devastating disorder that is often unrecognized or misdiagnosed in its early stages. Despite the current lack of unequivocally effective treatment, recognition of early-stage dementia may offer substantial benefits. These include avoidance of inappropriate treatment related to misdiagnosis and time for the patient and family to address issues of financial, legal, and medical care planning. This Clinical Practice Guideline is intended to help primary care providers recognize and assess Alzheimer's disease and related dementias in the early stages. Differential diagnosis is beyond the scope of the guideline; however, the guidline contains a list of resources for further clinical evaluation once probable dementia has been identified.

Dementia and Memory

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Author :
Publisher : Psychology Press
ISBN 13 : 1317916573
Total Pages : 318 pages
Book Rating : 4.3/5 (179 download)

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Book Synopsis Dementia and Memory by : Lars-Göran Nilsson

Download or read book Dementia and Memory written by Lars-Göran Nilsson and published by Psychology Press. This book was released on 2013-11-20 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: A negative effect of the ageing population is that more individuals are experiencing cognitive decline and some form of neurodegenerative disease. With the number of people experiencing dementia likely to double in the next 20 years, this change in society presents one of greatest challenges facing public health personnel in the 21st century. The aim of this volume is to describe research that is in progress, and the major findings that have been obtained in the scientific study of dementia. The chapters in the first section of the book focus upon early signs of dementia, and consider several approaches to finding early cognitive signs and biological markers of dementia. The second section considers whether dementia is inevitable for people who become very old, and features chapters on risk factors and proactive influences, cognitive reserve and intervention. Each chapter in the final section describes phenomena which are related to differences in function between memory systems, including anterograde memory in fronto-temporal dementia, and the role semantic memory and semantic cognition may play in developing an understanding of the development of the degenerative processes in dementia. With contributions from world-class researchers in this area, the volume offers a concise overview of key findings in recent research on dementia and memory. It will be of great interest to researchers and advanced students of cognitive psychology, and to those working in related fields, such as gerontology, rehabilitation sciences, and allied health.

The Neuropsychiatry of Alzheimer's Disease and Related Dementias

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Author :
Publisher : CRC Press
ISBN 13 : 9781841842196
Total Pages : 324 pages
Book Rating : 4.8/5 (421 download)

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Book Synopsis The Neuropsychiatry of Alzheimer's Disease and Related Dementias by : Jeffrey L. Cummings

Download or read book The Neuropsychiatry of Alzheimer's Disease and Related Dementias written by Jeffrey L. Cummings and published by CRC Press. This book was released on 2003-01-16 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer's disease and related dementias represent an increasing threat to public health, in addition to the stress they place upon patients, their families and caregivers. While historically the emphasis in studying Alzheimer's disease has been on cognitive decline, this unique, state of the art book rectifies this imbalance and addresses the key behavioral and neuropsychiatric disorders associated with dementing conditions. Written by a world famous leader in the field of dementia and neuropsychiatry, this dynamic text has been richly illustrated with graphs, brain imaging and pathology. Rigorously referenced, it is packed with essential information and will be an excellent resource for clinicians as well as an ideal teaching text.

Improving services and support for people with dementia

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Author :
Publisher : The Stationery Office
ISBN 13 : 0102945616
Total Pages : 76 pages
Book Rating : 4.1/5 (29 download)

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Book Synopsis Improving services and support for people with dementia by : Great Britain: National Audit Office

Download or read book Improving services and support for people with dementia written by Great Britain: National Audit Office and published by The Stationery Office. This book was released on 2007-07-04 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dementia is a term for a range of progressive, terminal organic brain diseases, including Alzheimer's. Some 560,000 people in England are estimated to have dementia, with a steeply rising trend over the coming years. Some 476,000 people are unpaid carers of people with dementia. Direct costs to the NHS and social care are currently at least £3.3 billion a year, but the overall annual economic burden is estimated at £14.3 billion. This report examines what health and social care services are available for people with dementia and their unpaid carers in England and whether they are providing effective and good quality support. Until 2005 the Department of Health attached little priority to dementia, and progress was hampered by a lack of good quality data, by stigma, and by the low level of political and national focus on older people's mental health. The NAO conclude that services are not currently delivering value for money to taxpayers or people with dementia and their families. Whilst health and social care services are spending significantly on dementia, spending is late - too few people are being diagnosed or being diagnosed early enough. Early interventions that are known to be cost-effective, and which would improve quality of life, are not being made widely available. Services in the community, care homes and at the end of life are not delivering consistently or cost-effectively against the objective of supporting people to live independently as long as possible in the place of their choosing. The rapid ageing of the population means costs will rise and services are likely to become increasingly inconsistent and unsustainable without redesign. Recommendations cover: improving diagnosis and early intervention; improving management of services; gearing the system to respond to the major challenges of dementia in the future.

The Neural Bases of Multisensory Processes

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Publisher : CRC Press
ISBN 13 : 1439812179
Total Pages : 800 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis The Neural Bases of Multisensory Processes by : Micah M. Murray

Download or read book The Neural Bases of Multisensory Processes written by Micah M. Murray and published by CRC Press. This book was released on 2011-08-25 with total page 800 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has become accepted in the neuroscience community that perception and performance are quintessentially multisensory by nature. Using the full palette of modern brain imaging and neuroscience methods, The Neural Bases of Multisensory Processes details current understanding in the neural bases for these phenomena as studied across species, stages of development, and clinical statuses. Organized thematically into nine sub-sections, the book is a collection of contributions by leading scientists in the field. Chapters build generally from basic to applied, allowing readers to ascertain how fundamental science informs the clinical and applied sciences. Topics discussed include: Anatomy, essential for understanding the neural substrates of multisensory processing Neurophysiological bases and how multisensory stimuli can dramatically change the encoding processes for sensory information Combinatorial principles and modeling, focusing on efforts to gain a better mechanistic handle on multisensory operations and their network dynamics Development and plasticity Clinical manifestations and how perception and action are affected by altered sensory experience Attention and spatial representations The last sections of the book focus on naturalistic multisensory processes in three separate contexts: motion signals, multisensory contributions to the perception and generation of communication signals, and how the perception of flavor is generated. The text provides a solid introduction for newcomers and a strong overview of the current state of the field for experts.

Dementia

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Publisher : Oxford University Press
ISBN 13 : 0199928460
Total Pages : 400 pages
Book Rating : 4.1/5 (999 download)

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Book Synopsis Dementia by : Bradford Dickerson

Download or read book Dementia written by Bradford Dickerson and published by Oxford University Press. This book was released on 2014-08-01 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dementia: Comprehensive Principles and Practice is a clinically-oriented book designed for clinicians, scientists, and other health professionals involved in the diagnosis, management, and investigation of disease states causing dementia. A "who's who" of internationally-recognized experts contribute chapters emphasizing a multidisciplinary approach to understanding dementia. The organization of the book takes an integrative approach by providing three major sections that (1) establish the neuroanatomical and cognitive framework underlying disorders of cognition, (2) provide fundamental as well as cutting-edge material covering specific diseases associated with dementia, and (3) discuss approaches to the diagnosis and treatment of dementing illnesses.

The Clinical Spectrum of Alzheimer's Disease

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Publisher :
ISBN 13 : 9789535167853
Total Pages : 378 pages
Book Rating : 4.1/5 (678 download)

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Book Synopsis The Clinical Spectrum of Alzheimer's Disease by : Suzanne De La Monte

Download or read book The Clinical Spectrum of Alzheimer's Disease written by Suzanne De La Monte and published by . This book was released on 2011 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Clinical Spectrum of Alzheimer's Disease: The Charge Toward Comprehensive Diagnostic and Therapeutic Strategies is highly informative and current. Acknowledged experts in the field critically review both standard and under-appreciated clinical, behavioral, epidemiological, genetic, and neuroimaging attributes of Alzheimer's disease. The collection covers diverse topics of interest to clinicians and researchers alike. Experienced professionals and newcomers to the field will benefit from the read. The strengths and weaknesses of current clinical, non-invasive, neuro-imaging, and biomarker diagnostic approaches are explained. The perspectives give fresh insights into the process of neurodegeneration. Readers will be enlightened by the evidence that the neural circuits damaged by neurodegeneration are much broader than conventionally taught, suggesting that Alzheimer's could be detected at earlier stages of disease by utilizing multi-pronged diagnostic approaches. This book inspires renewed hope that more effective treatments could be developed based upon the expanding list of potential therapeutic targets.

Textbook of Neural Repair and Rehabilitation

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Publisher : Cambridge University Press
ISBN 13 : 1107011671
Total Pages : 693 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Textbook of Neural Repair and Rehabilitation by : Michael Selzer

Download or read book Textbook of Neural Repair and Rehabilitation written by Michael Selzer and published by Cambridge University Press. This book was released on 2014-04-24 with total page 693 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 1 of the Textbook of Neural Repair and Rehabilitation covers the basic sciences relevant to recovery of function following injury to the nervous system.

Imaging Acute Neurologic Disease

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Publisher : Cambridge University Press
ISBN 13 : 1107035945
Total Pages : 393 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Imaging Acute Neurologic Disease by : Massimo Filippi

Download or read book Imaging Acute Neurologic Disease written by Massimo Filippi and published by Cambridge University Press. This book was released on 2014-09-11 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Acute neurologic diseases encompass a wide spectrum of medical illnesses with neurological manifestations which require rapid clinical, paraclinical and laboratory evaluation as patients are evaluated in the emergency department or acute care clinics. In the last decade, imaging has assumed far greater importance in the initial assessment of these patients, and is responsible for much of the cost and resources in the early, critical evaluation. However the optimal approach to utilization of imaging for thorough, yet efficient and cost-responsible care remains poorly defined for many acute neurologic presentations"--Provided by publisher.

Animal and Translational Models for CNS Drug Discovery

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Publisher : Academic Press
ISBN 13 : 0080920411
Total Pages : 1367 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Animal and Translational Models for CNS Drug Discovery by : Robert A. McArthur

Download or read book Animal and Translational Models for CNS Drug Discovery written by Robert A. McArthur and published by Academic Press. This book was released on 2008-11-27 with total page 1367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal and Translational Models for CNS Drug Discovery combines the experience of academic, clinical and pharmaceutical neuroscientists in a unique collaborative approach to provide a greater understanding of the relevance of animal models of neuropsychiatric disorders and their role as translational tools for the discovery of CNS drugs being developed for the treatment of these disorders. The focus of this three-volume series of essays is to present a consensual picture of the translational value of animal models from leading experts actively involved in the use of animal models for understanding fundamental neurobiology of CNS disorders and the application of this knowledge to CNS drug discovery, and clinical investigators involved in clinical trials, drug development and eventual registration of novel pharmaceuticals. Each volume of the Animal and Translational Models for CNS Drug Discovery series is dedicated to the development and use of animal models in key therapeutic areas in psychiatric, neurologic and reward deficit disorders. Each volume has introductory chapters expressing the view of the role and relevance of animal models for CNS drug discovery and development from the perspective of (a) academic basic neuroscientific research, (b) applied pharmaceutical drug discovery and development, and (c) issues of clinical trial design and regulatory agencies limitations. Each volume examines the rationale, use, robustness and limitations of animal models in relevant therapeutic areas and discusses the use of animal models for target identification and validation. The clinical relevance of animal models is discussed in terms of major limitations in cross-species comparisons, clinical trial design of drug candidates, and how clinical trial endpoints could be improved. The aim of this series of volumes on Animal and Translational Models for CNS Drug Discovery is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery. - Provides clinical, academic, government and industry perspectives fostering integrated communication between principle participants at all stages of the drug discovery process - Critical evaluation of animal and translational models improving transition from drug discovery and clinical development - Emphasizes what results mean to the overall drug discovery process - Explores issues in clinical trial design and conductance in each therapeutic area - Each volume is available for purchase individually.

Dementias

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Publisher : Springer Science & Business Media
ISBN 13 : 8847021499
Total Pages : 311 pages
Book Rating : 4.8/5 (47 download)

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Book Synopsis Dementias by : S. Govoni

Download or read book Dementias written by S. Govoni and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: To a certain extent the dementias have been forgotten diseases until just recen tly when they were brought to the attention of the general public and health authorities as a result of the increasing number of cases in the aging popula tion, especially among famous people, and because of the efforts of private foundations. The goals of the present volume are to present the dementias to health prac titioners, to provide some basic information on their epidemiology and biolo gical basis and to discuss the diagnostic and clinical problems that physicians and institutions face when caring for demented patients. This book explores the various types of dementias and is not limited to Alzheimer's disease although, as expected, more information is available and presented on this pathology. On the other hand, a few fundamental questions on dementia can only be answe red through a comparison of the various forms. Examples of such questions are the following: Is the loss of cerebral tissue sufficient to cause dementia? Are there thresholds or is there a continuous progression toward the irreversible development of dementia? Are there common pathways in the dementing pro cess? Are there common risk factors? Comparative analysis allows the common and distinctive patterns of the various dementias to be defined, ultimately lea ding to more focused therapeutic interventions.

Analyzing Neural Time Series Data

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Publisher : MIT Press
ISBN 13 : 0262019876
Total Pages : 615 pages
Book Rating : 4.2/5 (62 download)

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Book Synopsis Analyzing Neural Time Series Data by : Mike X Cohen

Download or read book Analyzing Neural Time Series Data written by Mike X Cohen and published by MIT Press. This book was released on 2014-01-17 with total page 615 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive guide to the conceptual, mathematical, and implementational aspects of analyzing electrical brain signals, including data from MEG, EEG, and LFP recordings. This book offers a comprehensive guide to the theory and practice of analyzing electrical brain signals. It explains the conceptual, mathematical, and implementational (via Matlab programming) aspects of time-, time-frequency- and synchronization-based analyses of magnetoencephalography (MEG), electroencephalography (EEG), and local field potential (LFP) recordings from humans and nonhuman animals. It is the only book on the topic that covers both the theoretical background and the implementation in language that can be understood by readers without extensive formal training in mathematics, including cognitive scientists, neuroscientists, and psychologists. Readers who go through the book chapter by chapter and implement the examples in Matlab will develop an understanding of why and how analyses are performed, how to interpret results, what the methodological issues are, and how to perform single-subject-level and group-level analyses. Researchers who are familiar with using automated programs to perform advanced analyses will learn what happens when they click the “analyze now” button. The book provides sample data and downloadable Matlab code. Each of the 38 chapters covers one analysis topic, and these topics progress from simple to advanced. Most chapters conclude with exercises that further develop the material covered in the chapter. Many of the methods presented (including convolution, the Fourier transform, and Euler's formula) are fundamental and form the groundwork for other advanced data analysis methods. Readers who master the methods in the book will be well prepared to learn other approaches.

Dementia Registries Around the World

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Publisher :
ISBN 13 : 9780733437557
Total Pages : 158 pages
Book Rating : 4.4/5 (375 download)

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Book Synopsis Dementia Registries Around the World by : Karolina Krysinska

Download or read book Dementia Registries Around the World written by Karolina Krysinska and published by . This book was released on 2016-11-30 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Patient registries are well embedded in many fields of medicine and public health, including cancer and cardiovascular diseases. Still, registries collecting data on patients with dementia are relatively new. Also, despite many advantages and tangible practical outcomes, to-date only a limited number of organisations systematically collect dementia data on a national or local/regional level. This report presents the current situation in regards to dementia registries worldwide. The document is based on a systematic review of dementia registries and a review of the literature on best practice in establishing and operating patient and health services/quality registries."--Page 9.

Evidence-based Dementia Practice

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Publisher : John Wiley & Sons
ISBN 13 : 0470752335
Total Pages : 923 pages
Book Rating : 4.4/5 (77 download)

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Book Synopsis Evidence-based Dementia Practice by : Nawab Qizilbash

Download or read book Evidence-based Dementia Practice written by Nawab Qizilbash and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 923 pages. Available in PDF, EPUB and Kindle. Book excerpt: The era of therapeutic nihilism in dementia has ended, with the emergence of agents for symptomatic treatment, those that delay the course of the disease or prevent the onset of dementia, and new methods to manage symptoms. With the expansion of therapies, there is a clear danger of being overwhelmed by the volume of data. This book is designed to collect this information, distil what is relevant and reliable, and present it in a format that is useful to clinicians who manage and treat people with dementia. The book is designed to bring together the latest, best and practical evidence on all aspects of management, from diagnosis and therapy to social and ethical considerations. The editors are all dynamic clinicians involved in the care of patients with dementia and the evaluation of therapies. Two of the editors are the leaders of the Cochrane Collaboration for the examination of therapies for dementia. There are no other books that take such a practical and problem-oriented or approach to the diagnosis and management of dementia. Furthermore none but this can be described as truely evidence-based.

Imaging in Neurodegenerative Disorders

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Publisher : Oxford University Press, USA
ISBN 13 : 0199671613
Total Pages : 585 pages
Book Rating : 4.1/5 (996 download)

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Book Synopsis Imaging in Neurodegenerative Disorders by : Luca Saba

Download or read book Imaging in Neurodegenerative Disorders written by Luca Saba and published by Oxford University Press, USA. This book was released on 2015 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text summarizes the latest developments in imaging techniques and other new diagnostic methods as applied to the neurodegenerative disorders.